... MPTP (B), in the presence of 200 lM MPTP (C), in the presence of 100 lM MPP+ (D), in the presence of 200 lM MPP+ (E), in the presence of 100 lM MPTP and 50 lM dopamine (F), in the presence of 200 ... cells overexpressing a-synuclein have shown the formation of aggregates of the protein on exposure to dopamine [16] In vitro experiments probably provide a better understanding of the role of various ... 240 h of incubation a-Synuclein incubated (A) alone (k = 245 nm), (B) in the presence of 100 lM MPTP (k = 245 nm), (C) in the presence of 200 lM MPTP (k = 245 nm), (D) in the presence of 100...
Ngày tải lên: 14/02/2014, 19:20
... equations of the first kind (the “hedging equations”) have solutions Furthermore, the integral operators appearing in these equations (the “hedging operators”) turn out to be adjoint of the martingale ... part of the present theorem We now turn to the issue of so called “martingale modelling”, and remark that one of the main morals of the martingale approach to arbitragefree pricing of derivative ... number of values on every compact interval If all functions above are deterministic and analytic also in the t-variable, then the maturities can be chosen to be the same for every t Proof The main...
Ngày tải lên: 16/02/2014, 02:20
Tài liệu Báo cáo khoa học: NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles doc
... respectively retained in the centre of the interhelical linker and at the C-terminus of micelle-associated VpUcyt Position of VpUcyt relative to the micelle NMR signal intensities of individual VpUcyt ... of the observed VpUcyt structure One of the most studied activities of VpU is the induction of CD4 degradation in the endoplasmatic reticulum of infected CD4+ cells Only the cytoplasmic domain ... undetectable in the presence of Mn2+ The solvent-exposed C-terminus of VpUcyt probably pointed away from the surface of the micelle The three amide cross-peaks originating from the hydrophobic...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt
... identify the site of action of the fatty acids in the plasmin molecule, the amidolytic activity of two truncated plasmin variants was examined (Fig 8) Miniplasmin (des-kringle 1-4 plasmin) contains the ... product in the presence of stearate (Fig 5B) In line with earlier observations [6], no autocleavage of plasmin was seen during the activity assay in the presence of enzyme substrate (Fig 5, insets) ... are the rate constants for inactivation of the respective forms of the enzyme In independent measurements with fatty acids we showed that the inactivation of free plasmin for the duration of the...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc
... cofactor activity of the reaction intermediate, FVaint This facilitated the determination of loss of FVa cofactor activity during the initial stage of inactivation and minimized the in uence of the k306 ... Kinetic analysis of the inactivation of FVa by APC in the presence and absence of heparin Initial rates of FVa inactivation were determined at various concentrations of FVa in the presence (d) or ... activated was then determined using S-2238 [2] APC-catalyzed inactivation of FVa Time courses of FVa inactivation by APC were determined by following the loss of FXa cofactor activity of FVa in the prothrombinase...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine pptx
... of the active site may alter the excess-substrate effect Thus the response of cholinesterases to excess-substrate binding appears to involve the intricate interplay of a variety of residues in ... required in order to obtain the dependent variable (k) in terms of the independent variable (pH) Fitting was performed using SIGMAPLOT v. 4.16 kcat is the turnover number in the absence of excess ... behaviour The most obvious indication of this modulation appears at high pH where the limiting value of bkcat tends to approach the limiting value of kcat as the size of the residue at position 328 increases...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt
... parameters of RNase-A in the presence of these amino acids and amino acid derivatives, and values of DGD°, measured in triplicate, are given in Table The effect of polyols on the kinetic parameters ... hydration of the protein domain is the driving force of protein stabilization or folding [3,4] Furthermore, the effect of osmolytes on the functional activity of an enzyme has also been investigated ... efficiency in the presence of this group of osmolytes Interestingly, there is a linear relationship between DDGD° and Dlog(kcat ⁄ Km) in the presence of methylamines and sugar However, the slopes of the...
Ngày tải lên: 07/03/2014, 00:20
large-scale hydrothermal synthesis of wo3 nanowires in the presence of k2so4
... growth of the WO3 nanowires With the addition of different inorganic salts, the compositions and the corresponding properties of the solution are different in the hydrothermal conditions The changes ... need the anisotropy during the growth process for the nanoparticles In our experiments, the presence of the salts is also an important factor influencing the crystallization process and the growth ... the TEM image of the obtained WO3 with the addition of NaNO3, KNO3 and Na2SO4 It can be seen that no WO3 nanowires could be obtained with any content of KNO3 With an increase in the content of...
Ngày tải lên: 20/03/2014, 13:04
WORMS: IDENTIFYING IMPACTS ON EDUCATION AND HEALTH IN THE PRESENCE OF TREATMENT EXTERNALITIES ppt
... Group 1) The change in overall infection rates between the first two years of the program (captured in Xijt in the above model) may also have affected individual deworming treatment decisions Infection ... through the program in 1998 (Table III) .16 Since approximately 80 percent of the students enrolled prior to the start of the proTABLE III PROPORTION OF PUPILS RECEIVING DEWORMING TREATMENT IN PSDPa ... the deworming intervention that we examine allows us to capture the overall effect of deworming even in the presence of externalities across individuals within schools School-level randomization...
Ngày tải lên: 22/03/2014, 15:20
Báo cáo khoa học: Kinetic analysis of zymogen autoactivation in the presence of a reversible inhibitor pptx
... trypsinogen autoactivation in the presence of 100 lM p-amindinobenzamidine As seen in this figure, the presence of p-amindinobenzamidine lengthened the lag time considerably Similarly, the values of ... autoactivation of trypsinogen by trypsin gives a straight line, indicating that p-amindinobenzamidine is a competitive inhibitor for the trypsinogen autoactivation reaction From the slope and intercept ... activation of trypsinogen is quantitative, the increase in trypsin activity shows the appearance of newly processed trypsin during the reaction, and the y scale (ordinate) in Fig can then be expressed...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: "What’s There to Talk About? A Multi-Modal Model of Referring Behavior in the Presence of Shared Visual Information" potx
... model of how collaborative pairs adapt their language in the presence (or absence) of shared visual information A successful computational model of referring behavior in the presence of visual information ... detailed theoretical understanding of human referring behavior in the presence of shared visual information They suggest that shared visual information of the task objects and surrounding workspace ... space For instance, we have varied the proportion of the workspace that is visually shared with the Helper in order to examine the impact of a limited field -of- view We have offset the spatial...
Ngày tải lên: 24/03/2014, 03:20
Báo cáo khoa học: Kinetics of inhibition of acetylcholinesterase in the presence of acetonitrile doc
... were in good agreement with the parameter estimates obtained in the absence of the inhibitors (see above) In the case of gallamine investigated in the presence of MeCN, the calculation of the kinetic ... involvement of PAS in the processes of AD, the use of PAS inhibitors and dual-site inhibitors of AChE allows for the inhibition of the catalytic activity of the enzyme and also lowers the incidence of ... Specic velocity plot for the inhibition of AChE by gallamine in the absence of MeCN (B) Plot of int0 (int0)1) and int1 (int1)1) versus the reciprocal concentrations of gallamine Inhibition kinetics...
Ngày tải lên: 29/03/2014, 23:20
Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt
... the toxicity of Ab [21–25] The in vivo effect of metals can be complex [26,27], and the presence of Cu2+, Zn2+ or Ca2+ significantly accelerates aggregation of Ab in vitro [19,28,29] The binding ... formed in the presence of Cu2+ [(i) and (iii) ] or Zn2+ [(ii) and (iv)], or as fibrils formed in the presence of EDTA [ (v) and (vi)] The amount of amyloid or amyloid-like structure within the different ... analysis of metal-complexed Ab aggregates A E C ever, assembly in the presence of metals is unlikely to involve the same intermolecular interactions as within fibrils, as removal of the metals...
Ngày tải lên: 30/03/2014, 01:20
Báo cáo "Thermomechanical characteristics of rigid poly(vinyl chloride) crosslinked by a peroxide in the presence of trimethylolpropane trimethacrylate " pdf
... concentration is observed in the presence of phr of TMPTMA of the PVC crosslinked samples decreases with increasing concentration of TMPTMA up to 15 phr Therefore, in order to obtain PVC having the highest ... improves the molecular mobility, melting and softening of PVC and a result, Ts decreases with increasing Table 1: Softening point of the PVC samples containing different concentrations of DAPC ... softening depends on the melting of these crystallites, but can be changed by a chemical crosslinked network [5] The crosslinking influences on the softening point (Ts) of the PVC samples in comparing...
Ngày tải lên: 03/04/2014, 15:20
Báo cáo sinh học: " Recombinant Tula hantavirus shows reduced fitness but is able to survive in the presence of a parental virus: analysis of consecutive passages in a cell culture" pot
... variant and that the lower fitness of the recombinant virus can not be increased by pre-passaging in cell culture The observed survival time of the recTULV in the presence of the Page of (page number ... the observed survival time of the recTULV in the presence of the original variant TUL02 seems to be sufficient for transmission of a recombinant virus, in a hypothetical in vivo situation, from ... 3'-noncoding region of the S segment seems to be involved in recombi- nation events, leading, however, to the deletion of the hairpin-forming sequences (A Plyusnin, unpublished observations) The role...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học:" Recombinant Tula hantavirus shows reduced fitness but is able to survive in the presence of a parental virus: analysis of consecutive passages in a cell culture" ppt
... variant and that the lower fitness of the recombinant virus can not be increased by pre-passaging in cell culture The observed survival time of the recTULV in the presence of the Page of (page number ... the observed survival time of the recTULV in the presence of the original variant TUL02 seems to be sufficient for transmission of a recombinant virus, in a hypothetical in vivo situation, from ... 3'-noncoding region of the S segment seems to be involved in recombi- nation events, leading, however, to the deletion of the hairpin-forming sequences (A Plyusnin, unpublished observations) The role...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo hóa học: " Performance analysis of distributed ZF beamforming in the presence of CFO" pptx
... toward the receiver P1 obtained by averaging the instantaneous SNR over the channel realizations and indicates the SNR gain over the single-user (SU) single-input-single-output (SISO) case We derive ... collected at the receiver The diversity order is calculated by evaluating the resulting slope of the average bit error rate curve, and the derivation of the diversity order is proposed in Section 3.2 ... 3.1 Average SNR gain The instantaneous SNR denotes the power of the received signal, after equalization, averaged over the noise and symbols In the following derivations, we assume a zero-forcing...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: "A new low-complexity angular spread estimator in the presence of line-of-sight with angular distribution selection" pptx
... statistics of the instantaneous frequency (IF) of the received signal at the mobile station In [23], ML estimators that only use samples of both the fading envelope and the fading phase are derived In ... reduced even more by averaging the correlation coefficients over all antenna pairs spaced by the same distance, before using the LUT, instead of averaging the individual AS estimates over all ... eigenvalues, but by the product of the characteristic matrix and the eigenvectors En The estimated AoAs are then the arguments of the complex roots of the obtained pseudospectrum One drawback of the...
Ngày tải lên: 20/06/2014, 22:20
báo cáo hóa học: " Topological confinement in an antisymmetric potential in bilayer graphene in the presence of a magnetic field" pptx
... of the states in the kink potential In a semiclassical view, the movement of the carriers is constrained by the potential, which prevents the formation of cyclotron orbits We also calculate the ... y-component of the wavelength ky = ky l and (b,d) the external magnetic field B0 The inset in (a) shows the wavespinors for kyl = proximity of an antikink induces a strong dependence of the states on the ... transition In contrast to the single kink profile the shift in the intragap energies of the kink-antikink potential leads to a non-zero value for the oscillator strength at ky = (red solid curve in (a))...
Ngày tải lên: 21/06/2014, 02:20
báo cáo hóa học: " Joint optimization of MIMO radar waveform and biased estimator with prior information in the presence of clutter" pot
... examine the CRB obtained by only using the prior information In this case, let the matrix D in (6) be equal to 3k× 3k and all the other parameters remain the same as the previous examples The variant ... relative error of the clutter estimate is defined as the ratio of the estimation error of the initial total clutter power to the exact one Figure shows the CRB versus the estimation error of the initial ... receiver (in units of wavelengths), respectively Let the weighted matrix M = I and g = in the case of the weighted norm constraint, and T = I and g = 0.5 in the other case In the following examples,...
Ngày tải lên: 21/06/2014, 02:20