identification of rease with potential activity against hsv 2 genome

Báo cáo y học: " Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination" pps

Báo cáo y học: " Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination" pps

... 0. 021 2 0.0104 0.0 120 0.0 125 0. 029 0 0.0156 0.0184 — — — 1. 725 8 2. 05 82 2.5 722 6 .25 41 4.8909 10.019 9 .23 66 8 .25 60 3.9387 5.1585 6.3008 — — — a c 0.0700 0.0799 0.0165 0. 025 3 0.0038 0.0135 0.0 42 0.0073 ... 0. 620 0.475 0.456 0.483 0.573 0.446 0.630 0 .29 1 0.579 — — — 0.1350 0.1000 0.1 620 0 .28 20 0. 320 0 0 .27 30 0.1610 0.3360 0.0790 0.3 820 0 .20 70 — — — 0.853 0 .22 0 0.031 0.0 32 0.017 0.0148 0.0138 0. 021 8 ... Verapamil Talinolol Rifampicin UK 22 4,671 854 789 670 421 454 363.5 822 544 2. 2 3.8 0.8 4.7 2. 9 2. 7 1.8 2. 1 × 10-6 1.1 × 10-6 2. 2 × 10-6 × 10-6 1.5 × 10-5 1.5 × 10-6 2. 0 × 10-6 3.0 × 10-7 Pappbaa,...

Ngày tải lên: 13/08/2014, 16:21

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Báo cáo khoa học: Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles pdf

Báo cáo khoa học: Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles pdf

... Journal 27 7 (20 10) 3564–3574 ª 20 10 The Authors Journal compilation ª 20 10 FEBS A Yamane et al Preferred substrate peptide for TGase A TGase B 0 10 20 (min) 10 20 (min) 10 20 TGase 2 10 20 Factor ... TGase 2 10 20 Factor XIII 10 20 (min) DMC DMC E6 E8 E46 E 12 E 125 E50 E4 E 42 E10 E18 E111 E21 E115 E18 E51 E115 E1 E2 E8 E 12 E46 E10 E51 Fig Evaluation of the reactivities of the selected peptides ... Chem 26 5, 21 971 21 978 22 Kim I-G, Gorman JJ, Park S-C, Chung S-I & Steinert PM (1993) The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse skin J Biol Chem 26 8, 126 82 126 90...

Ngày tải lên: 29/03/2014, 21:20

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báo cáo hóa học:" Research Article Extremal Values of Half-Eigenvalues for p-Laplacian with Weights in L1 Balls" potx

báo cáo hóa học:" Research Article Extremal Values of Half-Eigenvalues for p-Laplacian with Weights in L1 Balls" potx

... < λL 2m 2m −→ ∞ , 2. 22 R ≤ λ2m · · · −→ ∞ Moreover, R λ0 a, b > ⇐⇒ b t dt < a t dt < or 2. 23 ∀m ∈ Z 2. 24 Proof Compared with results in , we need only prove Σ2m a, b ∈ λL 2m R a, b , λ2m a, ... a, b }2/ p 2. 15 is a solution of 2. 4 Given a, a1 , a2 , b1 , b2 ∈ L1 , write a if a ≥ and a t dt > Write a1 , b1 ≥ a2 , b2 a2 , b2 if a1 , b1 ≥ a2 , b2 and both a1 t > a2 t and if a1 ≥ a2 and ... half-eigenvalue problem of 2. 1 is equivalent to the φp x λa t φp x 0, a.e t ∈ 0, 2. 42 If a 0, then a, a ∈ W1 Theorem 2. 2 shows that all positive Dirichlet eigenvalues of 2. 42 consist of a sequence {λD...

Ngày tải lên: 21/06/2014, 11:20

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Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf

Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf

... Journal 27 8 (20 11) 28 –45 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 31 Regulation of MMP activity E Hadler-Olsen et al prodomain of the enzyme remained intact [24 ] The specific activity of ... knowledge with respect to structural and functional bases for allosteric control of FEBS Journal 27 8 (20 11) 28 –45 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 29 Regulation of MMP activity ... activation of proMMP -2 [28 ] It appears that bone sialoprotein also can regulate the activity of active MMP -2 by modulating the inhibitory effect of TIMP -2 and synthetic MMP-inhibitors [28 ,29 ] The...

Ngày tải lên: 15/03/2014, 00:20

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Báo cáo khoa học: Acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (lyso-PAF AT) activity in cortical and medullary human renal tissue docx

Báo cáo khoa học: Acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (lyso-PAF AT) activity in cortical and medullary human renal tissue docx

... )6 CaCl2 10 M CaCl2 10)5 M CaCl2 10)4 M CaCl2 10)3 M CaCl2 10 )2 M EDTA mM EDTA 10 mM EDTA mM + CaCl2 10)3 EDTA mM + CaCl2 10 )2 MgCl2 10)6 M MgCl2 10)5 M MgCl2 10)4 M MgCl2 10)3 M MgCl2 10 )2 M a ... in the de novo biosynthesis of platelet-activating factor Properties of a unique CDP-choline, 1-alkyl -2- acetyl-sn-glycerol 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 choline-phosphotransferase ... microsomes 15.6 ± 2. 6 (n ¼ 4) 24 .9 (n ¼ 2) 2. 1 ± 0.5 (n ¼ 4) 3. 72 (n ¼ 2) 90.4 ± 14.7 (n ¼ 4) 100.6 (n ¼ 2) 1.49 ± 0 .25 (n ¼ 4) 2. 92 (n ¼ 2) Ó FEBS 20 03 Lyso-PAF acetyltransferase activity in human...

Ngày tải lên: 17/03/2014, 03:20

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báo cáo hóa học: " Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD" pptx

báo cáo hóa học: " Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD" pptx

... Immunol 20 03, 3 :23 -35 Stein M, Keshaw S, Harris N, Gordon S: Interleukin potently enhances murine macrophage mannose receptor activity: a 17 18 19 20 21 22 23 24 25 26 27 28 marker of alternative ... 3: Comparison of alternative activation gene profile Tg -27 56 TNFα NOS2 AG1 CHI3L1 CHI3L2 YM1* FIZZ1** MRC1 Tg-SwDI AD Increased No Change Increased Increased No Change Increased Increased No Change ... revisited J Leukocyte Biol 20 04, 72: 621 - 627 Nguyen M, Julien J, Rivest S: Innate immunity: The missing link in neuroprotection and neurodegeneration Nat Rev Neurosci 20 02, 3 :21 6 -22 6 Adams D, Hamilton...

Ngày tải lên: 19/06/2014, 22:20

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Báo cáo hóa học: " Research Article Power Allocation Strategies for Distributed Space-Time Codes in Amplify-and-Forward Mode" docx

Báo cáo hóa học: " Research Article Power Allocation Strategies for Distributed Space-Time Codes in Amplify-and-Forward Mode" docx

... P2,1 , P2 ,2 , , P2,R ] and the positive definite diagonal matrices U and V are defined as ⎡ U = diag⎣ 2 P1 f2 g2 P1 f1 g1 , σ 21 P1 + N1 σ f2 P1 + N1 f 2 ⎤ P1 fR gR ⎦ , , , σ 2R P1 + N1 f ⎡ 2 ... can express Pe (R) given in (26 ) as ∞ Pe (R) = pr γr = 2Ar e−Br γr K0 Ar γr (21 ) R r =1 , π /2 c π e−g γ/(2sin φ) pmax γ dφdγ π /2 c = π Mmax g − dφ, 2sin2 φ (27 ) (22 ) where Mmax (−s) = Eγ (e−sγ ... in (20 ), the MGF of γmax = max{γ1 , 2 , , γR } is given by Ar = N2 σ 2r P1 + N1 f P1 P2 σ 2r σgr f , Br = N1 , P1 σ 2r f ⎛ Proof The proof is given in Appendix A Define γmax max{γ1 , 2 ,...

Ngày tải lên: 21/06/2014, 19:20

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research report  'using the activity in pairs and in groups to teach writing in english'

research report 'using the activity in pairs and in groups to teach writing in english'

... involved, but not staying too long with any group since the main initiative for writing should rest with students Group activity has two practical benefits in the teaching of writing Firstly, it overcomes ... during the last few years Most of the games below are typical ones to meet the target of teaching writing to the first year students with an intermediate knowledge of English who study in Vinh ... students to exchange their lists, but not their texts, with a pair from the other half of the class Đại học Vinh Tạp chí khoa học, tập XXXVII, số 2b -20 07 - Explain that they must try to reconstruct...

Ngày tải lên: 29/06/2014, 19:15

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Báo cáo toán học: "Asymptotics for the distributions of subtableaux in Young and up-down tableaux" pps

Báo cáo toán học: "Asymptotics for the distributions of subtableaux in Young and up-down tableaux" pps

... Lemma to g(u) after the change of variables, we have C α∈Φ |η |2 |u |2 − α(u)α(η) exp − 2 2 N + the electronic journal of combinatorics 11 (2) (20 06), #R29 g(u) = + O(N −1 /2 ) (43) 13 The only term ... β of N steps, and the number of Young tableaux with N cells which contain a specific subtableau of shape µ is thus the number of walks the electronic journal of combinatorics 11 (2) (20 06), #R29 ... )/(2n + − i − j) = For the terms with i fixed and at most r the electronic journal of combinatorics 11 (2) (20 06), #R29 19 but j > r, we have n ηi + ηj = 2n + − i − j j=r+1 n µi + 2n + − i − j 2n...

Ngày tải lên: 07/08/2014, 08:22

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Báo cáo khoa học: "Surgical treatment for different forms of hernias in sheep and goats" ppt

Báo cáo khoa học: "Surgical treatment for different forms of hernias in sheep and goats" ppt

... peehs ni sainreh lanimodba fo sesaC 03 92 82 72 62 52 42 32 22 12 02 91 81 71 61 51 41 31 21 11 01 1 elba T staog dna peehs ni sainreh fo smrof tnereffid rof tnemtaert lacigruS fo eerged eht dna ... kliS kliS tugtaC tugtaC tugtaC tugtaC tugtaC tugtaC tugtaC lairetam erutuS 2 2 1 1 1 4 4 2 2 2 snoisehda fo eergeD seY M2 elameF Y idgaN seY M8 elameF Y idgaN seY M4 elameF Y idgaN seY M5 elameF ... gnihsilbuP ssegruB ,3 52 p de ht7 yregruS yranireteV RE knarF 3001-999 ,25 1 ,8691 cossA deM teV mA J peehs ni sainreh latinegnoC WH dlopieL ,MS sinneD 22 ,2 ,0791 J teV eniuqE laof eht ni yregrus...

Ngày tải lên: 07/08/2014, 20:23

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Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps

Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps

... 140, 1 42; the neighourhood was composed, on average, of 85.5% sessile oaks; nine pedunculate oaks encircled by trees of the same species (ped/ped); families: 22 0, 22 2, 22 5, 23 7, 24 6, 24 7, 24 9, ... distribution of population types Watsonia 13, 20 9 -22 4 Semerikov LF, Glotov NV, Zhivotovskii LA (1988) Example of effectiveness of analysis of the generalized variance of traits in trees Soviet Journal of ... characters independent of the dimensions of the leaves were considered (character numbers 20 , 23 , 26 , 29 , 32, 33, 35, 36, 37, 39, 40, 41; DFAc) Since we did not dispose of repetitions, it was...

Ngày tải lên: 08/08/2014, 18:21

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Báo cáo khoa hoc:" Genetic relationship between cyclic ovarian activity in heifers and cows and beef traits in males" ppt

Báo cáo khoa hoc:" Genetic relationship between cyclic ovarian activity in heifers and cows and beef traits in males" ppt

... Anim Sci 76 (1998) 22 72 22 78 [22 ] van der Werf J.H.J., de Boer I.J.M., Estimation of additive genetic variance when base populations are selected, J Anim Sci 68 (1990) 3 124 –31 32 [23 ] Wolfe M.W., ... all pedigree information is taken into account, the estimation of genetic parameters would be unbiased [9, 20 ,22 ] 2. 2 .2 Estimation of genetic parameters Variance and covariance components were ... Heifer BW 12 BCS 12 ICP (ICO) 0. 32 ± 0.03 (0.11 ± 0.04) AFP (AFO) 0 .28 ± 0.05 (0.38 ± 0.04) −0 .26 ± 0.05 (−0.06 ± 0.08) −0 .22 ± 0.09 (−0.53 ± 0.11) −0.14 ± 0.10 (0.06 ± 0.14) −0.13 ± 0.08 (−0 .23 ± 0.10)...

Ngày tải lên: 09/08/2014, 18:21

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Báo cáo y học: "Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury" pps

Báo cáo y học: "Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury" pps

... 18 19 20 21 22 23 24 25 26 27 Hanaoka M, Droma Y, Naramoto A, Honda T, Kobayashi T, Kubo K: Vascular endothelial growth factor in patients with high-altitude pulmonary edema J Appl Physiol 20 03, ... of Pathology Experience and Literature Review Mol Diagn 1997, 2( 3) :21 7 -23 0 Godinho SIMA: An animal model of the acute respiratory distress syndrome (ARDS) European Respiratory Journal 20 02, 20 :486s ... with HBSSS and the protein of interest added After 48 hours incubation, cells were washed with PBS and incubated with 100 μl of Trypsin-EDTA (Sigma, Poole, UK) When the cells Table 2: Table of...

Ngày tải lên: 12/08/2014, 14:20

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Báo cáo y học: " G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]" pps

Báo cáo y học: " G-CSF and IL-8 for early diagnosis of sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial [ISRCTN91123847]" pps

... experience of the NICHD Neonatal Research Network Pediatrics 20 02, 110 :28 5 -29 1 Fischer JE, Ramser M, Fanconi S: Use of antibiotics in pediatric intensive care and potential savings Intensive Care Med 20 00, ... J: Incidence and outcome of polymicrobial ventilatorassociated pneumonia Chest 20 02, 121 :1618-1 623 Song JX, Ahn CW: An evaluation of methods for the stratified analysis of clustered binary data ... the stratified analysis of clustered binary data in community intervention trials Stat Med 20 03, 22 :22 05 -22 16 Giamarellos-Bourboulis EJ, Mega A, Grecka P, Scarpa N, Koratzanis G, Thomopoulos G,...

Ngày tải lên: 12/08/2014, 20:20

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Multi-beneficial for mitigation of climate change in Vietnam and Indochina countries by development of biomass energy project

Multi-beneficial for mitigation of climate change in Vietnam and Indochina countries by development of biomass energy project

... 1/5/2C 12 1/5 /2- 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5/2C 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 ... 1/5 /20 12 1/5 /20 12 6:00 AM 8.6 93 93 6:00 AM 8.6 93 6:30 AM 6:30 AM 8.6 8.6 92 92 6:30 AM 7:00 AM 8.6 92 8.7 7:00 AM 8.7 8.7 92 92 92 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 1/5 /20 12 ... 1/16 /20 12 12. -0CPM 28 S38 4.4 0.94 1/16 /20 12 12: 00 PM 28 S38 4.4 0.94 1/16 /20 12 12: 00 PM 1/16 /20 12 1:00 PM 28 4.4 0.94 27 .87 838 684 4.3 0. 92 1:00 PM 27 .87 684 4.3 0. 92 1/16/2C 12 1:00 PM 11/5 /20 11...

Ngày tải lên: 18/03/2015, 13:20

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Regulation of sla2p by activity in endocytosis and actin organization by the ark1 prk1 family of kinases

Regulation of sla2p by activity in endocytosis and actin organization by the ark1 prk1 family of kinases

... 20 1 .2. 2.3 Pan1p 21 1 .2. 2.4 yAP1801 and yAP18 02 22 1 .2. 2.5 Ent1p and Ent2p 22 1 .2. 2.6 Scd5p 23 1 .2. 2.7 Sla2p/HIP1/R ... 1 .2. 2.7 Sla2p/HIP1/R 23 1 .2. 2.7.1 Sla2p 23 1 .2. 2.7 .2 HIP1 and HIP1R .27 1 .2. 2.8 Vesicle Scission 30 1 .2. 2.9 Proteins regulating Clathrin-mediated ... 121 122 133 136 138 LIST OF TABLES Table 2. 1 Table 2. 2 Table 2. 3 Table 5.1 List of Strains List of Plasmids List of Antibodies Result of high-copy suppressor screen ix 47 49 52 130 LIST OF ABBREVIATIONS...

Ngày tải lên: 14/09/2015, 08:50

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Báo cáo khoa học: Function of microRNA-375 and microRNA-124a in pancreas and brain doc

Báo cáo khoa học: Function of microRNA-375 and microRNA-124a in pancreas and brain doc

... 21 9574611 7494 723 2 9798308 6545 426 0 6 128 029 7 6 520 9494 176956 62 180 828 745 21 9574674 7494 729 5 97983 92 65454368 6 128 0383 6 520 9578 176957770 180 828 8 12 position 12 However, miR- 124 b has not been found in ... processing FEBS Journal 27 6 (20 09) 6509–6 521 Journal compilation ª 20 09 FEBS No claim to original French government works N N Baroukh and E Van Obberghen 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 and ... hsa-miR- 124 a1 hsa-miR- 124 a2 hsa-miR- 124 a3 mmu-miR- 124 a1 mmu-miR- 124 a2 mmu-miR- 124 a3 MI0000783 MI00007 92 MI0000443 MI0000444 MI0000445 MI0000716 MI0000717 MI0000150 8 20 14 21 9574611 7494 723 2 9798308...

Ngày tải lên: 29/03/2014, 22:21

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Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf

Tài liệu Báo cáo khoa học: Experimental proof for a signal peptidase I like activity in Mycoplasma pneumoniae, but absence of a gene encoding a conserved bacterial type I SPase pdf

... assembly of the term- FEBS Journal 27 2 (20 05) 28 92 29 00 ª 20 05 FEBS 17 18 19 20 21 22 23 24 25 26 inal organelle of Mycoplasma pneumoniae Mol Microbiol 51, 917– 924 Feldner J, Gobel U & Bredt W (19 82) ... (146–1 52) ATW(ox)VFER (146–1 52) ATW (2 · ox)VFER (146–1 52) TLQDLXVEQPVTPYTPNAGLAR (1 82 20 3) VDGVAQDTVHFGSGQESSWNSQR (20 4 22 6) VNGVAQDTVHFGSGQESSWNSQR (20 4 22 6) Sulfonated at N (position 26 ) Sulfonated ... oxidation of tryptophan or the conversion of asparagine to aspartic acid, as observed for peptide 146–1 52 (ATWVFER) and peptide 20 4 22 6 (VNGVAQDTVHFGSGQESSW FEBS Journal 27 2 (20 05) 28 92 29 00 ª 20 05...

Ngày tải lên: 19/02/2014, 18:20

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Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf

Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf

... 106.3 25 .3 80.9 20 .9 9.5 11.3 21 0.7 23 .2 187.5 82. 0 65.4 16.6 13.7 11.8 1.9 23 2.8 22 5.7 7.1 WT100 DCs ± 2. 15 ± 2. 15 ± 0.19 ± 0.19 ± 0 .24 ± 0 .24 and the quencher group Figure 6B shows the results of ... 20 20 25 25 30 30 30 35 35 35 D Substrate + CF 20 25 .54 E Substrate + LF 25 F Substrate + EF 5 10 Elution time (min) 25 .19 10 10 15 15 15 20 20 25 25 30 30 35 35 G Substrate + CF + PepA 20 22 .87 ... 15 15 20 20 25 25 30 30 35 35 Relative Fluorescence 20 22 .91 25 . 92 25 30 35 Relative Fluorescence Relative Fluorescence Fig RP-HPLC profiles of peptide fragments obtained after digestion of the...

Ngày tải lên: 07/03/2014, 09:20

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