i phase ii funding commitment commercial contribution optional

... percent of Phase I awardees submitting a Phase II application will successfully receive a Phase II award Instructions and eligibility requirements for submitting Phase II grant applications will be ... begin thinking about and seeking commitments from private sector or Federal non-SBIR/STTR funding sources in anticipation of Phases II and III The commitments should be obtained prior to the Phase ... Phase II grant application submission The commitment for Phase III may be made contingent on the DOE-supported research or R&D meeting some specific technical objectives in Phase II, which, if met,...

Ngày tải lên: 23/03/2014, 03:20

... Đèn báo nước vào lọc nhiên liệu 42 Đèn báo tắt hệ thống t i khí 43 Đèn báo l i xe 44 Đèn báo bật đèn cos 45 Đèn báo lọc gió bị bẩn 46 Đèn báo chế độ l i tiết kiệm nhiên liệu 47 Đèn báo bật hệ ... thông tin 11 Đèn báo sấy nóng bugi/dầu diesel 12 Đèn cảnh báo tr i sương giá 13 Đèn báo bật công tắc khóa i n 14 Đèn báo chìa khóa không nằm ổ 15 Đèn cảnh báo khóa bấm i u khiển từ xa hết pin 16 ... mức thấp 22 Đèn báo thông tin đèn xi-nhan 23 Đèn báo l i đèn ngo i thất 24 Đèn cảnh báo đèn phanh 25 Đèn cảnh báo lọc hạt diesel 26 Đèn báo l i móc kéo 27 Đèn cảnh báo l i hệ thống treo 28 Đèn cảnh...

Ngày tải lên: 15/03/2015, 21:24

... (since – for) Vd: I ve played video games since I was six Diễn tả việc xảy lặp l i nhiều lần khứ (once, twice, third times…) Vd: I ve watched Harry potter six times Trạng từ: Ngo i trạng từ n i ... pass this test (cơ h i khoang 50% cao hơn) You might pass this test (cơ h i 50% trở xuống) II Các câu giao tiếp I d like to invite you to… Thank you I d be delighted to acccept Would you join us…? ... dụng N i chung tùy duyên! XEM VÀ LÀM B I TẬP TRANG 69 GHI NHỚ CÁC GI I TỪ THEO SAU ĐỘNG TỪ Dạng câu ý kiến đề nghị (p 72) II III S + suggest + S +(should) V1 How about + Ving What about + Ving Why...

Ngày tải lên: 15/03/2015, 21:25

... issued from large burls, are difficult to identify with respect to their age, and it is virtually impossible to define the proportions of contribution of root and stem issue With these restrictions ... physical work and time [3] This makes it difficult to increase the study area The total root biomass for the excavated area is presented in table III The dry weight values are subdivided into ... Quercus coccifera shrublands to the Mediterranean region and its capacity to live in hard climatic and edaphic conditions The continuity of belowground biomass after the fire in this vegetation probably...

Ngày tải lên: 08/08/2014, 14:22

... 6.3 Livelihood activities, strategies and financial capital 150 6.3.1 Income and livelihood activities 151 6.3.2 Livelihood changes 154 6.3.3 Livelihood capabilities 155 6.4 Natural and physical ... Man, Li Jianfeng, Ifeanyi Nduka, Cui Yuanzheng, Sally Duan, Lin Lijie, Sunil KC, Pan Jian, Yang Minxing, Xu Jiaxing, Xue Jie, Liu Ye, Wu Dan, Si Fung Hoi, Danica Chan, Chen Yanyan, Cai Jixuan, ... also to the ones I failed to mention here VII TABLE OF CONTENT Abstract in English I Abstract in Chinese III Published papers during PhD study IV Acknowledgements V List of Figures, Tables, Boxes...

Ngày tải lên: 29/03/2016, 14:20

... Arg in the a-helix and the residues are located at positions (i, i + 3) or (i, i + 4), which is believed to be stabilizing [42] In addition, CTX has Met and Phe side chains at positions (i, i + ... increase (higher Thr : Ser ratio) The a-helix region of thermophilic xylanases is stabilized by various strategies including additional hydrogen bonding, salt bridges or disulfide bridges It is ... Rouvinen, J & Leisola, M (2001) Combination of weakly stabilizing mutations with a disulfide-bridge in the a-helix region of Trichoderma reesei endo-1,4-b-xylanase II increases the thermal stability...

Ngày tải lên: 20/02/2014, 23:20

... (FITC)-conjugated Gri€onia simplicifolia lectin II (GSII) or peanut agglutinin (PNA) (EY Laboratories, San Mateo, CA, USA), and further incubated with monoclonal anti-HA Ig to detect the transporter protein expressed ... speci®cÕ residues described previously [15] The solid asterisks indicate ÔUGT-speci®cÕ residues conserved in DmUGT Underlining indicates a potential glycosylation site of DmUGT Fig Expression ... with an appropriate plasmid as speci®ed below were stained with FITC-GS -II lectin and anti-HA antibody as in Fig in (A); and cell extracts were subjected to Western blot analysis as in Fig in...

Ngày tải lên: 21/02/2014, 15:20

... Interestingly, silencing of CrkII reduced the elongation of protrusions but did not disrupt the reorientation of the Golgi Cas ⁄ CrkII association regulates the activation of Rac via a functional ... Polarization CrkII Rac1 Protrusion Cell migration Fig Schematic presentation of regulation of cell migration by Cas Cas utilizes Nck2 to activate Cdc42 and induce cell polarization Cas also utilizes ... transfectants during wound healing, whereas depletion of CrkII did not affect Cdc42 activation Discussion Polarization of cells in the direction of migration is required for the organized movement...

Ngày tải lên: 23/03/2014, 03:20

... on Hsp90 inhibitor sensitivity This raises the intriguing possibility that the a ⁄ b isoform ratio may be an important determinant of such inhibitor sensitivity in mammalian cells In an independent ... sensitivity to the Hsp90 inhibitor radicicol The most striking finding was that it is only expression of Hsp90b, not comparable expression of Hsp90a, which renders yeast highly sensitive to radicicol ... sensitivity is normally associated with compromised activity of the Hsf1p CT domain [14,22], the compromised heat activation of this domain with Hsp90b present in the yeast (Fig 1C) is a plausible...

Ngày tải lên: 23/03/2014, 07:20

... with EDTA Residual activity of antithrombin was analyzed using the chromogenic Actichrome AT III (American Diagnostica, Greenwich, CT, USA) kit, which quantifies antithrombin III activity as follows ... catalyzes peptidyl arginine to citrulline, is closely associated with RA [33] We recently found that recombinant human PADI4 protein inactivated human antithrombin III via citrullination in vitro We ... heparin-binding region of antithrombin However, such binding did not stimulate the activity of antithrombin as did heparin and heparan; in fact, it blocked the ability of antithrombin to inhibit...

Ngày tải lên: 09/08/2014, 06:22

... varicella vaccine Pediatrics 2000, 105:84-88 Salzman MB, Garcia C: Postexposure varicella vaccination in siblings of children with active varicella Pediatr Infect Dis J 1998, 17:256-257 Kohl I, ... ovalbumin either alone, with MPL™ (10 μg, Sigma) or adsorbed onto Aluminium hydroxide (200 μg, 5) Five of the 15 mice were bled every days in rotation, and anti-ovalbumin IgG endpoint titers determined ... size proteoliposomes derived from Neisseria meningitidis: An effective adjuvant for generation of CTL responses to peptide and protein antigens Vaccine 2006, 24:2692-2699 Singh M, Chakrapani...

Ngày tải lên: 11/08/2014, 08:21

... mental health Integrated service models require integrated funding In addition to feasibility issues of this model with regards to recurrent funding, the sustainability of what was identified as an ... sufficient and multidisciplinary clinical supervision and adequate initial competency are prerequisites for a successful program There are limitations to this study that are worth noting It is ... this service In addition, the evaluation aims to provide addiction and HCV specialists with information to facilitate improved health care relationships when treating patients with substance...

Ngày tải lên: 11/08/2014, 18:20

... Shortcourse empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit A proposed solution for indiscriminate antibiotic prescription Am J Respir Crit Care Med ... Wedzicha JA: Nasal intermittent positive-pressure ventilation in weaning intubated patients with chronic respiratory disease from assisted intermittent, positive-pressure ventilation Respir Med ... similar gas parameters, which is consistent with the literature [11] In addition, there were no statistically significant differences in cardiorespiratory parameters measured in the first minute...

Ngày tải lên: 13/08/2014, 10:20

... with extensive clinical experience with trial design and with patients with Turner syndrome ◦ ethicist who was also a pediatrician endocrinologist ◦ nurse with extensive clinical experience with ... psychosocial functioning of individuals with short stature is largely indistinguishable from their peers Opportunity costsefficiency* Considering maximizing impact on health for a given level ... small patients, there is a medical utility in facilitating normal functioning (reaching car pedals, kitchen cabinets etc), which would impact positively on the intrinsic value of the intervention...

Ngày tải lên: 13/08/2014, 11:22

... DNA-binding domain The E/F domain is the ligand-binding domain, which contains the AF2 ligand-dependent activation domain The amino-terminal A/B domain contains the AF1 ligand-independent activation ... apolipoprotein C-III [54] Furthermore, PPARα up-regulates apolipoprotein AI and A -II in humans, which leads to an increase in plasma high-density lipoprotein (HDL) cholesterol Additional PPARα ... non-steroidal anti-inflammatory drug (NSAID) aspirin Moreover, in individuals with familial adenomatous polyposis, an inherited predisposition to multiple colorectal polyps, the NSAID sulindac can...

Ngày tải lên: 13/08/2014, 13:20

... other uncertainties, utilizing this simplification is justified Based on this, the probability Pn,t x that individual n becomes infected during simulation time step tx can be derived as I ⎛ Pn,t ... are Figure Relationship between contact duration and intensity Relationship between contact duration and intensity This figure shows the relationship between contact intensity (I, II, III) and ... http://www.tbiomed.com/content/6/1/25 Every ingested infectious organism has a certain probability to survive until it reaches its target tissue and can initiate infection [18,27] We assume that this survival probability is a constant,...

Ngày tải lên: 13/08/2014, 16:20

... Milli Georgiadis for providing reagents In final, I would like to thank the Biochemistry and Molecular Biology Department at Indiana University iii Abstract Steven B Cogill PURIFICATION OF SIMPL ... pathway is inhibited by inactivation of IRAK-1 catalytic activity, and the IL-1 signaling pathway is maintained by the structural presence of the IRAK-1 protein independent of its catalytic activity ... Medicine) The purified ∆23SIMPL protein lacks the first 22 amino acids of SIMPL and contains four additional amino terminal residues The AminoLink® Immobilization Kit was purchased from Thermo Scientific...

Ngày tải lên: 24/08/2014, 12:43

... social group (social class, regional identity, ethnic minorities) b) Social interaction (differing levels of formality; as outsider and insider) c) Belief and behavior (moral, religious beliefs; ... of societal and individual interaction Values or critical cultural awareness is an ability to evaluate critically on the basis of explicit criteria, perspectives, practices andproducts in one‟s ... part in classroom activities When I organize games or competitions in the class, not every student really joins the activities It is not because of they are passive or don‟t find the activities interesting...

Ngày tải lên: 25/12/2015, 17:18

... different stakeholders demand different priorities The most simple prioritization is dividing requirements into mandatory and nice-to-have type of requirements Other possibility is to use an integer ... modules, etc.), (iii) establishing relationships to system modeling, analysis, and verification The main contribution of this paper is the definition of a meta-model and UML profile for requirements management ... main phases shown in Figure Requirements elicitation is the first phase of the process It involves investigating possible stakeholders and listing their main requirements for the product The discovery...

Ngày tải lên: 21/06/2014, 05:20

... are described in more detail in Appendix B Copyright © 2007, IGI Global Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited Simpo PDF ... required in Copyright © 2007, IGI Global Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited Simpo PDF Merge and Split Unregistered Version ... engineering practices The novelty of XP is based Copyright © 2007, IGI Global Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited Simpo...

Ngày tải lên: 27/06/2014, 06:20