human papillomavirus hpv vaccine

Bài giảng human papillomavirus (HPV)

Bài giảng human papillomavirus (HPV)

... HVQY HPV HVQY HPV 130 HPV HPV6,11-u nhú sinh dục HPV 16-50%K cổ tử cung HPV1 8-K biểu mô tuyến và thần kinh nội tiết

Ngày tải lên: 10/06/2014, 15:28

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HUMAN PAPILLOMAVIRUS AND RELATED DISEASES – FROM BENCH TO BEDSIDE A DIAGNOSTIC AND PREVENTIVE PERSPECTIVE potx

HUMAN PAPILLOMAVIRUS AND RELATED DISEASES – FROM BENCH TO BEDSIDE A DIAGNOSTIC AND PREVENTIVE PERSPECTIVE potx

... [96,97]. Detection of human papillomavirus (HPV) E6/E7 oncogene expression may be more predictive of cervical cancer risk than test HPV- DNA.Commercial test targeting HPV mRNA has been Human Papillomavirus ... potential Worldwide, HPV- 16 is the most common HPV type across the spectrum of HPV related cervical lesions. In women with ICC (invasive cervical cancer), the most common HPV types are HPV- 16,18,33,45,31 ... 22 HPV types with GP5+/6+ PCR 15 HPV types with YBT L1/GP-1 PCR, and 18 HPV types with GP5+/6+ PCR. These multiplex HPV genotyping (MPG) methods have been compared with other well established HPV...

Ngày tải lên: 08/03/2014, 19:20

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Báo cáo khoa học: Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7 doc

Báo cáo khoa học: Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7 doc

... distantly related HPV E7 proteins. Fragment K D (nM) DG a (kcalặmol )1 ) DDG b (kcalặmol )1 ) Full-length protein HPV1 6 E7 2.4 0.2 )11.6 0.05 – HPV1 8 E7 7.8 ± 0.5 )10.9 ± 0.04 0.7 ± 0.06 HPV1 1 E7 108 ... The human papillomavirus E7 oncoprotein. Virology 384, 335–344. 20 Helt AM, Funk JO & Galloway DA (2002) Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus ... retinoblastoma gene product binding site on human papillomavirus type 16 E7 protein. J Biol Chem 269, 6842–6850. 36 Smotkin D & Wettstein FO (1987) The major human papillomavirus protein in cervical...

Ngày tải lên: 22/03/2014, 21:20

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Báo cáo khoa học: Viral entry mechanisms: human papillomavirus and a long journey from extracellular matrix to the nucleus docx

Báo cáo khoa học: Viral entry mechanisms: human papillomavirus and a long journey from extracellular matrix to the nucleus docx

... infectious entry pathway of human papillomavirus type 33 pseudovirions. Virology 299, 279–287. 65 Bousarghin L, Touze A, Sizaret PY & Coursaget P (2003) Human papillomavirus types 16, 31, ... and accumulation of human papillomavirus type 6B L2 protein. Virology 213, 321–327. 80 Pyeon D, Pearce SM, Lank SM, Ahlquist P & Lambert PF (2009) Establishment of human papillomavirus infection ... matrix; EEA, early endosomal antigen; ER, endoplasmic reticulum; HPV, human papillomavirus; HSPG, heparan sulfate proteoglycan; PV, papillomaviruses; si, small interfering. 7206 FEBS Journal 276...

Ngày tải lên: 23/03/2014, 04:20

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Báo cáo khoa học: Human papillomavirus 16 E7 protein inhibits interferon-c-mediated enhancement of keratinocyte antigen processing and T-cell lysis docx

Báo cáo khoa học: Human papillomavirus 16 E7 protein inhibits interferon-c-mediated enhancement of keratinocyte antigen processing and T-cell lysis docx

... cervical epithelium with one of a range of oncogenic human papillomaviruses (HPVs) can initiate cervical cancer. The majority of high-risk papillomavirus infections of immunocompe- tent individuals ... presentation. Abbreviations CTL, cytotoxic T lymphocyte; E7-KC, keratinocyte expressing HPV 16 E7; HPV, human papillomavirus; IFN, interferon; IRF, interferon regulatory factor; KC, keratinocyte; ... SW, Duerr A, Heilig CM, Shah KV, Klein RS, Cuuvin S & Schuman P et al. (2006) Time to clearance of human papillomavirus infection by type and human immunodeficiency virus serostatus. Int J Cancer...

Ngày tải lên: 29/03/2014, 00:20

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Báo cáo hóa học: " HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future" pdf

Báo cáo hóa học: " HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future" pdf

... the HPV- 010 Study Group: Comparison of the immunogenicity and safety of CervarixTM and Gardasilđ human papillomavirus (HPV) cervical cancer vaccines in healthy women aged 18-45 years. Human Vaccines ... of Quadrivalent Human Papillomavirus (HPV; Types 6, 11, 16, and 18) L1 Virus-Like Particle Vaccine on Infection and Disease Due to Oncogenic Nonvaccine HPV Types in Generally HPV- Naive Women ... with infectious COPVin beagle dogs. Vaccine 2001, 19:2783-92. 32. Margaret Stanley: Immunobiology of HPV and HPV vaccines. Gynecol Oncol 2008, 109:S15-S21. 33. GlaxoSmithKline Vaccine HPV- 007 Study Group: Sustained...

Ngày tải lên: 18/06/2014, 16:20

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Báo cáo sinh học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L" pot

Báo cáo sinh học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L" pot

... papillomavirus- like particle (VLP) vaccine displaying HPV1 6 L2 epitopes induces cross-neutralizing antibodies to HPV1 1. Vaccine 2007, 25:2001-10. 14. Ishii Y, Tanaka K, Kanda T: Mutational analysis of human papil- lomavirus ... maintained Alignment of L1 amino acid sequences of papillomavirusesFigure 1 Alignment of L1 amino acid sequences of papillomaviruses. Numbers to the left represent human papillomavirus types. Numbers on the ... author Abstract Background: A human papillomavirus (HPV) virion is composed of capsid proteins L1 and L2. Several cysteine residues are located on L1 of various HPVs at markedly similar relative...

Ngày tải lên: 18/06/2014, 18:20

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Báo cáo sinh học: " The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient c" pptx

Báo cáo sinh học: " The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient c" pptx

... Alonso A, Auvinen E: Human papillomavirus type 16 E5 protein. Papillomavirus Report 2004, 15:1-6. 55. Cid-Arregui A, Juarez V, zur Hausen H: A synthetic E7 gene of human papillomavirus type 16 ... between infection of certain human papillomavi- rus (HPV) species within the Alphapapillomavirus genus and malignant growth of the human cervix epithelium [1- 3], as HPV sequences have been found ... Antibodies to HPV- 16 E6 and E7 proteins as markers for HPV- 16-associated invasive cervical cancer. Virology 1992, 187:508-514. 16. Dillner J: Mapping of linear epitopes of human papillomavirus type...

Ngày tải lên: 18/06/2014, 18:20

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Báo cáo hóa học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1" pdf

Báo cáo hóa học: " Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1" pdf

... papillomavirus- like particle (VLP) vaccine displaying HPV1 6 L2 epitopes induces cross-neutralizing antibodies to HPV1 1. Vaccine 2007, 25:2001-10. 14. Ishii Y, Tanaka K, Kanda T: Mutational analysis of human papil- lomavirus ... maintained Alignment of L1 amino acid sequences of papillomavirusesFigure 1 Alignment of L1 amino acid sequences of papillomaviruses. Numbers to the left represent human papillomavirus types. Numbers on the ... author Abstract Background: A human papillomavirus (HPV) virion is composed of capsid proteins L1 and L2. Several cysteine residues are located on L1 of various HPVs at markedly similar relative...

Ngày tải lên: 20/06/2014, 01:20

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Báo cáo hóa học: " The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells" ppt

Báo cáo hóa học: " The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells" ppt

... Alonso A, Auvinen E: Human papillomavirus type 16 E5 protein. Papillomavirus Report 2004, 15:1-6. 55. Cid-Arregui A, Juarez V, zur Hausen H: A synthetic E7 gene of human papillomavirus type 16 ... between infection of certain human papillomavi- rus (HPV) species within the Alphapapillomavirus genus and malignant growth of the human cervix epithelium [1- 3], as HPV sequences have been found ... human papillomavirus type 11 E7 protein with TAP- 1 results in the reduction of ATP-dependent peptide trans- port. Clin Immunol 2001, 101:94-99. 53. Alonso A, Reed J: Modelling of the human papillomavirus...

Ngày tải lên: 20/06/2014, 01:20

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Báo cáo hóa học: " p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein" docx

Báo cáo hóa học: " p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein" docx

... inhibit HPV 11 replication [28,29]. Here we have shown that p53 can also inhibit HPV 16 DNA replication. The HPV 16 E2 protein can induce apoptosis in HPV- transformed cells and in some non -HPV- transformed ... with a plasmid containing the HPV 16 origin of replication (pOri) and plasmids expressing HPV 16 E1 and the HPV 16 E2 protein (top panel) or HPV 16 E1 and the HPV 16 E2m1 protein (bottom panel) ... down-regulation The induction of apoptosis in HPV- transformed and non -HPV- transformed cellsFigure 2 The induction of apoptosis in HPV- transformed and non -HPV- transformed cells. (A) HPV- transformed HeLa cells...

Ngày tải lên: 20/06/2014, 01:20

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Báo cáo hóa học: " Transplacental transmission of Human Papillomavirus" pptx

Báo cáo hóa học: " Transplacental transmission of Human Papillomavirus" pptx

... more than two types of HPV DNA (30.6%) were identified. HPV DNA in the placenta HPV DNA was detected in 12 placentas (24.5%) of the 49 HPV DNA positive pregnant women (HPV DNA+) who Table 1: ... future HPV DNA be researched in the normal endometrium of women of reproductive age. The possible consequence of fetal exposure to HPV should be observed. Background Human papillomavirus (HPV) , ... maternal risks of human papillomavirus infection. Cancer Detect Prev 1995, 19:196-205. 52. Fredericks BD, Balkin A, Daniel HW, Schonrock J, Ward B, Frazer IH: Transmission of human papillomaviruses...

Ngày tải lên: 20/06/2014, 01:20

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Báo cáo hóa học: " Sexually transmitted Human Papillomavirus type variations resulting in high grade cervical dysplasia in North-East North Dakota and North-West Minnesota" pot

Báo cáo hóa học: " Sexually transmitted Human Papillomavirus type variations resulting in high grade cervical dysplasia in North-East North Dakota and North-West Minnesota" pot

... infections with HPV 16 and 2 samples (12 %) with HPV 31. Two samples (12%) were doubly infected with HPV 16 and 18, 3 sam- ples (18 %) with HPV 16 and 31 and 1 sample 6 % with HPV 18 and 31. Triple ... detection of sequenced and still unsequenced human papillomavirus HPV Infection in Grand Forks, ND (control group) versus Roseau, MN (experimental group)Figure 1 HPV Infection in Grand Forks, ND (control ... sample (6 %) were doubly infected with HPV 16 and 31 and 4 samples (24 %) were doubly infected with HPV 18 and 31. Two samples (12 %) showed triple infections with HPV 16,18 and 31. One sample tested...

Ngày tải lên: 20/06/2014, 01:20

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Báo cáo hóa học: " Characterization of neutralizing epitopes within the major capsid protein of human papillomavirus type 33" pot

Báo cáo hóa học: " Characterization of neutralizing epitopes within the major capsid protein of human papillomavirus type 33" pot

... versa, HPV3 3-specific sequences were introduced into HPV1 6 L1 for ectopic expression. Ten different hybrid L1 proteins (HPV3 3:16BC; HPV3 3:16DE; HPV3 3:16FGa; HPV3 3:16FGb; HPV3 3:16HI; HPV1 6:33BC; HPV1 6:33DE; ... pseudovirions, formed by HPV1 6 L1 proteins containing amino acids 51–58 of HPV3 3 L1 and HPV1 6 L2, assembled into particles which could be neutralized by both HPV3 3- and HPV1 6-specific antibodies, ... citation purposes) Type-specificity of HPV- reactive antibodiesFigure 1 Type-specificity of HPV- reactive antibodies. A) Infection of human 293TT cells with HPV1 6 and HPV3 3 pseudovirions in the presence...

Ngày tải lên: 20/06/2014, 02:20

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