human fibroblasts for large scale omics investigations of atm gene function

... interactions, we assembled an integrated dataset of 31,609 interactions between 7,748 human proteins, forming a framework for the interpretation of human functional genomics data These data are collected ... establish measures of accuracy that are useful for the evaluation and integration of upcoming datasets We established two benchmarks for assessing the quality of large- scale human protein interaction ... constructed as the sets of numerical codes for the KEGG pathway diagrams associated with each gene The functional annotation benchmark is composed of all pairs of human genes sharing annotation...

Ngày tải lên: 14/08/2014, 14:21

... classification, this is an example of the frame adj-obj -for- to-inf, shown in Figure 2, (using AVM notation in place of COMLEX s-expressions) Part of the output of RASP for this sentence is shown in ... unseen in the output of the classifier (17 vs 28) indicate that the new system is capable of detecting a higher number of SCFs The main reason for better performance is the ability of the new system ... classifier output For adjectives only of the 30 gold standard SCFs are unseen, resulting in better recall (57.6% vs 47.2% for nouns) For verbs, subcategorization acquisition performance often correlates...

Ngày tải lên: 17/03/2014, 04:20

... 368 s for ours) and 7∼12 times faster for decoding (2.881 ms for M ALLET, 5.028 ms for C RF ++, and 0.418 ms for ours) This result demonstrates that learning and decoding CRFs for large- scale ... performs 5∼50 times faster for training (1,774 s for M ALLET, 18,134 s for C RF ++, Experiment We evaluated our method on six large- scale natural language data sets (Table 1): Penn Treebank3 for ... a method of choosing appropriate values for the setting function δ of the active set and for the constant value ω of the inactive set These two problems are closely related The size of the active...

Ngày tải lên: 23/03/2014, 17:20

... after a two-fold increase of metabolite A (+) Perturbation Boundary Static part + + of kinetic properties for large- scale metabolic pathways Therefore, the applicability of the dynamic method has ... employed for large- scale analyses of metabolism [4,15,16] Assuming a steady-state condition, MFA provides a flux distribution as the solution of the mass balance equation without the need for rate ... metabolomics and proteomics allow largescale measurement of flux distributions [22], intracellular metabolite concentrations and amounts of enzymes [23] Figure A pathway map of the erythrocyte model...

Ngày tải lên: 13/08/2014, 23:20

... (wz,t,i,j ) end for wz,t,i+1,0 ← wz,t,i,P end for end for Collect/stack weights W ← [w1,t,S,0 | |wZ,t,S,0 ]T Select top K feature columns of W by norm and for k ← K v[k] = end for end for return ... results for algorithms and on the Europarl data (ep) for different devtest and test sets Europarl data were used in all runs for training and for setting the meta-parameter of number of epochs ... learning for SMT not only to large feature 18 sets but also to large sets of parallel training data Since inference for SMT (unlike many other learning problems) is very expensive, especially on large...

Ngày tải lên: 19/02/2014, 19:20

... hours of video testimonies in 32 languages Starting from an initial out -of- vocabulary (OOV) rate of 85%, we show that a small set of prioritized translations can be elicited from human informants, ... relatively small number of terms provide access to a large portion of the video content Similarly, a great number of highly specific terms describe only a small fraction of content Therefore, not every ... value for access to the archive The hierarchical arrangement of keyword phrases presents another issue: some concepts, while not of great value for access to segments of video, may be important for...

Ngày tải lên: 08/03/2014, 02:21

... consistent with general features of nanomaterials Diffraction peaks of Fig (a) SEM, (b) SEM, (c)TEM images of WO3 nanowires synthesized at 180 °C for 12 h with 40 g K2SO4 Fig XRD patterns of WO3 nanowires ... diameter of these uniform nanowires was about 10 nm and the length was up to several microns (Fig 1b) Therefore, the nanowires reached a high aspect ratio of more than 500 A TEM image of a single ... pressure, and composition of the solution [21] The formations of nanowires first need the anisotropy during the growth process for the nanoparticles In our experiments, the presence of the salts is also...

Ngày tải lên: 20/03/2014, 13:04

... count Dimensions of the vector consist of (the union of) all useful message types across all groups, and the value of a dimension in the vector is the number of appearances of the corresponding ... messages by values of the variables chosen above For each message group, create a message count vector y = [y1 , y2 , , yn ], where yi is the number of appearances of messages of type i (i = ... constant dimension for each vector, its runtime is linear in the number of vectors, so detection can scale to large logs yn = PPT y = Cn y, where P = [v1 , v2 , , vk ], is formed by the first...

Ngày tải lên: 30/03/2014, 16:20

... number of iterations, the worst case complexity of the algorithm is in: pre suc O(I · (2 · B + Nv · Nc · (Nc + Nc ))) When using large corpora with large numbers of bigrams the number of required ... set of words in each cluster, the total number of occurrences of each cluster in the training corpus, and the list of words preceeding each cluster For each word w in the predecessor list of a ... fraction of the words for exchange will increase the number of iterations required to converge In experiments we empirically determined that choosing a subset of roughly a third of the size of the...

Ngày tải lên: 31/03/2014, 00:20

... performance in terms of the expected number of routing hops and the number of messages exchanged as part of a node join operation This section focuses on another aspect of Pastry’s routing performance, ... properties of Pastry under node failures are considered 3.1 Routing performance The first experiment shows the number of routing hops as a function of the size of the Pastry network We vary the number of ... more of the issues and requirements of such applications and systems [1, 2, 5, 8, 10, 15] One of the key problems in large- scale peer-to-peer applications is to provide efficient algorithms for...

Ngày tải lên: 28/04/2014, 13:40

... stochastic gradient method for updating the beamformers 4.1 Stochastic gradient algorithm for beamformer update The algorithm for the beamformer update is a generalization of [14] and is described ... single-run performance of the antenna selection algorithm in [10] is also shown In Figure 5, the average performance of 100 runs for the above schemes is plotted in a larger span of iterations ... performance requirement in order to guarantee that the actual performance of the selected subset meets the requirement with minimum number of selected antenna Performance of adaptive beamforming...

Ngày tải lên: 21/06/2014, 01:20

... divergence of some of the values of Pl (i) (k) However, a rigorous proof of such a divergence is complicated by the interactive nature of the iterations of (6) and (9) As long as λl is large enough, ... convergence, Pl (i) (k) for each l becomes nonzero for some (at least one) of k = 1, 2, , K, and zero for the rest of k = 1, 2, , K Then for each k, there is a subset Sk of the network, corresponding ... values of K and for different values of the uniform link data rate rl = R in bits/s/Hz We see that for this network and the chosen range of data rates 0.2 ≤ R ≤ 0.4 bits/s/Hz, the optimal choice of...

Ngày tải lên: 22/06/2014, 06:20

... analyses The modelling of ring width and volume increment indices as a function of defoliation of the current and the past 10 years was performed using the MIXED procedure of the SAS system that ... model of growth in defoliated fir stands, Can J For Res 11 (1981) 206–214 [19] MacLean D.A., Effects of spruce budworm outbreaks on the productivity and stability of balsam fir forests, For Chron ... calculations Therefore, the general objective of this study is to test the predictive capacity of the historical records of defoliation to explain the growth pattern of individual balsam fir trees...

Ngày tải lên: 08/08/2014, 00:21

... erased The potential for real data loss is great; we should not be lulled into a false sense of security simply because hackers not often take advantage of their attacks There is a large but stratified ... way to backup genomics resources This would require a lot of storage space, but space is relatively cheap today: for example, Google offers free email accounts with gigabytes of storage to anyone ... specifics and scale of how best to aggregate security expertise, personnel, and resources for the use and benefit of all We believe there is great potential in aggregation and we offer the following...

Ngày tải lên: 14/08/2014, 14:22

... 8:R9 information Listed are the numbers and percentages of assembled fire ant sequences and of D melanogaster genes that match at least one of the second-level GO terms for molecular function, ... region of ant-bee homology is part of a conserved gene with a large intron (that is, >5,000 bp), these 23 ant-bee gene pairs are strong candidate Hymenoptera-specific genes Further examination of ... protein-coding genes at a cutoff expectation value (E) of 1e-20 and 1e-5, respectively (Figure 1a) By contrast, 6,431 (54.2%) had no similarity at all to genes in the nr database (E > 1) For many of these...

Ngày tải lên: 14/08/2014, 17:22

... progress of the jobs, and informs the users about the jobs’ statuses As large clusters are especially designed for needs of large scale scientific applications, total of idle cycles of workstations ... of time instead of High-Performance Computing which is highly-tuned systems for small number of jobs executed for short periods of time Condor Project, which began in 1988 in the University of ... using grid resources for large scale applications is managing every part of application manually, such as submission of tasks; waiting for completion of one task or group of tasks in order to...

Ngày tải lên: 30/10/2014, 20:07

Ngày tải lên: 14/11/2014, 06:38

... http://db.cs.yale.edu/hadoopdb/hadoopdb.html http://www.cubrid.org/blog/dev-platform/database-technology -for- large- scaledata/ http://hadoop.apache.org/ http://davidmenninger.ventanaresearch.com/2011/01/19/secrets-revealed-inmassively-parallel-processing-and-database-technology/ ... cung cấp đầu để xử lý tiếp truy vấn SQl viết chúng vào bảng database MapReduce function tích hợp vào SQL: SELECT FROM functionname( ON table-or-query [ PARTITION BY expr ] [ ORDER BY expr ] [...

Ngày tải lên: 08/07/2015, 16:05

... nội dung trình bày    Sự cần thiết MPP Large Scale Database Phương hướng thực thi MPP Một số hệ thống sở liệu thực thi MPP Sự cần thiết MPP Large Scale Database     Có nhiều dịch vụ giới ... http://db.cs.yale.edu/hadoopdb/hadoopd b.html http://www.cubrid.org/blog/devplatform/database-technology -for- largescale-data/ http://hadoop.apache.org/ 17 Xin chân thành cảm ơn! 18 ... SELECT FROM functionname( ON table-or-query [ PARTITION BY expr ] [ ORDER BY expr ] [ clausename ( arg ) ] ) 12 Aster Data Database 13 SQL-MapReduce Function 14 SQL-MapReduce Function 15...

Ngày tải lên: 08/07/2015, 16:08

... show that the positive definiteness of the generalized Hessian of the objective function in the inner subproblem is equivalent to the constraint nondegeneracy of the corresponding xi xii Summary ... results of the general partial PPA studied by Ha [52], we analyze the global and local convergence of our proposed partial PPA for solving (1.2) In [52], Ha presented a modification of the general ... subproblem, due to the presence of inequality constraints, we reformulate the problem as a system of semismooth equations By defining a smoothing function for the soft thresholding operator, we...

Ngày tải lên: 10/09/2015, 08:41