how genes play a role in cancer
Tài liệu StrategieS for SucceSS: How to Write a Grant in Cancer CAM docx
Ngày tải lên :
14/02/2014, 22:20
... Methodological Issues in Cancer CAM Research Multidisciplinary Approaches in Cancer Treatment Investigators are often interested in investigating multidisciplinary approaches in cancer care The advantages ... subgroup analyses See also valid analysis Asian A person having origins in the original peoples of the Far East, Southeast Asia, or the Indian subcontinent including, Cambodia, China, India, Japan, ... realistic in their estimates of accrual rates in clinical CAM research Accrual in clinical investigations using CAM products and interventions may be particularly challenging in accrual, especially...
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Báo cáo Y học: Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? ppt
Ngày tải lên :
23/03/2014, 21:20
... 5357 an anabolic stimulus, may largely induce increased translation across the board of mRNAs that are already actively being translated How could increased phosphorylation of eIF4E actually inhibit ... REGULATED PHOSPHORYLATION In higher animals – mammals and insects (at least in Drosophila) – eIF4E is a phosphoprotein It is phosphorylated by the MAP-kinase signal-integrating kinases Mnk1 and ... phosphorylation in mRNA translation, bearing in mind that the main mechanism governing the actual availability of eIF4E for translation is not its phosphorylation (which probably does not affect its binding...
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báo cáo khoa học: " Do mitochondria play a role in remodelling lace plant leaves during programmed cell death?" pps
Ngày tải lên :
11/08/2014, 11:21
... by asterisk) and showed absolutely no staining (Figure 3J and 3K) These mitochondria appeared to have dramatically degraded cristae and nearly indistinguishable membranes via TEM imaging and also ... significant decrease in perforation formation within the lace plant via CsA application indirectly indicates that the PTP pathway may play a role in cellular death within this system Although the involvement ... stages (M1M4) based on their location in a window stage leaf areole Our findings also indicate that within a single areole of a stage (window stage) leaf a gradient of TUNEL-positive nuclei staining...
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báo cáo hóa học:" Spontaneous regression of curve in immature idiopathic scoliosis - does spinal column play a role to balance? An observation with literature review" pot
Ngày tải lên :
20/06/2014, 04:20
... contributed in acquisition of data, revising the manuscript critically and given the final approval, JYH has contributed in acquisition of data and analysis and interpretation of data; and KPV and NM have ... differential pressure loading on the growth plate [31] Eular’s Law of viscoelastic buckling of a spine in the coronal and transverse planes Page of leading to a lateral bend and axial rotation/torsional ... radiograms by a single radiologist All radiograms were taken on a single X-ray machine to avoid any error By clinical as well as radiological examination, leg length discrepancy was ruled out in the...
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Báo cáo y học: "Migration events play significant role in genetic differentiation: A microsatellite-based study on Sikkim settlers" ppt
Ngày tải lên :
14/08/2014, 14:21
... that migratory events have played a significant role in the differentiation of mongoloids of India Background The origin, dispersal and antiquity of Homo sapiens in the Asian peninsula have attained ... population and exhibit a high level of diversity In India, mongoloids contribute approximately 3% of the total population, mainly inhabiting the hills and adjoining plains of Northeast and Central ... of ancient mongoloid migrations Genetics 1992, 130: 139-152 Saha N, Bhattacaryya SP, Mukhopadhyay B, Bhattacharyya SK, Gupta R, Basu A: A genetic study among the Lepchas of the Darjeeling area...
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Tài liệu Speedwealth - How to make a milion in your own business in 3 years or less doc
Ngày tải lên :
24/01/2014, 07:20
... Today’s interest rates are about the lowest they’ve been in a decade As for getting rich in real estate, that party is over too! That leaves owning your own business as the last bastion remaining ... it again, and again, and again 39 Power Principle: Once you have something that works, you concentrate on duplicating it 40 SPEEDWEALTH PRINCIPLE #5: DUPLICATE Once you have “something” that ... such as giving massages, there is a definite ceiling on your income Let’s face it, there are only so many massages a masseuse can give in a day! The same limitations hold true if you are a counselor,...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
Ngày tải lên :
18/02/2014, 04:20
... with a full-length furin cDNA, were permeabilized and stained with polyclonal antibodies against furin and GRASP55 Arrows show examples of membrane compartment containing GRASP55 and furin Scale ... receptor interacting protein (GRIP1) [55] Role of GRASP55 in MT1-MMP activation or inactivation no afterpotential D (INAD) protein [56] However, it can also be a PDZ-independent mechanism, as for example ... colleagues [35] GRASP55F in pCDNA3.1 Zeo+ contained a C-terminal FLAG tag Full-length GRASP55, GRASP55 PDZ1 (amino acids 1–107), GRASP55 PDZ2 (amino acids 84–172) and GRASP55 region (amino acids...
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Tài liệu Báo cáo khoa học: Differentiation stage-dependent preferred uptake of basolateral (systemic) glutamine into Caco-2 cells results in its accumulation in proteins with a role in cell–cell interaction pptx
Ngày tải lên :
20/02/2014, 01:20
... Glutamine incorporation in Caco-2 proteins determining the relative uptake of glutamine; (b) by searching for changes in the intestinal proteome; and (c) by examining glutamine incorporation into ... the alpha-actinin protein family, alpha-actinin 1, has been shown to be involved in cadherin-mediated cell–cell adhesion via alpha-catenins in adherens junctions of epithelial cells [53] The fact ... cytoplasmic proteins that can bind to the membrane surface in response to elevations in intracellular calcium [45] Annexin A2 is an F-actin binding protein and participates in the formation of...
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Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development docx
Ngày tải lên :
05/03/2014, 17:20
... determine that a putative signal peptide and a cleavage site exist in ePAD and AAH53724 (an egg and embryo abundant peptidylarginine deiminase), indicating they are likely secreted proteins (Fig arrow) ... cortical granules contain PAD To ascertain if mouse cortical granules contain PAD, antibodies made against mouse ePAD and human recombinant PAD V (anti-PAD V (N)) were used to label in vivo matured ... PAD and LCA-binding cortical granule components in in vivo Confocal Confocal scanning laser micrographs comparing distribution of PAD and LCA-binding cortical granule components in in vivo matured...
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Speedwealth: How to Make a Million in Your Own Business in 3 Years or Less docx
Ngày tải lên :
23/03/2014, 14:20
... Conditional Redistribution Rights Welcome to the best selling book, SpeedWealth™, from internationally renowned author and speaker, T Harv Eker You are encouraged to read and forward this book to anyone ... be able to use the information in it to help them toward their own financial independence The conditions for it's redistribution are as follows: 1) You may not sell this book either digitally ... You may not sell this book either digitally or in any printed hard copy format 2) You must forward this book completely intact with all 102 PDF pages included ...
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Báo cáo khoa học: No evidence for a role in signal-transduction of Na+/K+-ATPase interaction with putative endogenous ouabain potx
Ngày tải lên :
23/03/2014, 17:21
... another group in collaboration with Hamlyn [21] by means of two independent assays, a radioimmunoassay using an anti-ouabain Ig and an enzymatic assay using ouabain-sensitive Na+/K+ATPase from dog ... larger changes in intracellular Na+ and Ca2+ may thus be the result of a ouabain interaction with subpopulations of Na+/K+ATPase [27] An overall increase in intracellular Na+ was seen in the experiments ... latter may have a sublocalization critical for the observations looking at ouabain as a signal-transducer Experiments pointing to a pivotal role of ouabain in signal-transduction In the following,...
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báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
Ngày tải lên :
18/06/2014, 15:20
... setting of cancer, tumorigenesis RAGE is the link between inflammatory pathways and pathways promoting tumorigenesis and metastasis Characterizing the role of RAGE in vivo and in vitro can be ... leads to enhanced migration and invasion by colon cancer cell lines Increased RAGE expression in colon cancer has been associated with atypia, adenoma size, and metastasis to other organs Stage ... products in human organs Mod Pathol 2005, 18:1385-1396 Harashima A, Yamamoto Y, Cheng C, Tsuneyama K, Myint KM, Takeuchi A, Yoshimura K, Li H, Watanabe T, Takasawa S, Okamoto H, Yonekura H, Yamamoto...
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Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx
Ngày tải lên :
18/06/2014, 16:20
... treatment significantly attenuated some alterations (i.e increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, ... (TIRdomain-containing adapter-inducing interferon-b) joining the RIG-I/MDA5 pathway In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates IRAK4/IRAK1 These kinases ... prodrug Int J Cancer 2009, 124(11):2520-7 90 Jagan S, Ramakrishnan G, Anandakumar P, Kamaraj S, Devaki T: Antiproliferative potential of gallic acid against diethylnitrosamineinduced rat hepatocellular...
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báo cáo hóa học:" Triple-Nucleoside Analog Antiretroviral Therapy: Is There Still a Role in Clinical Practice? A Review" docx
Ngày tải lên :
20/06/2014, 08:20
... Montaner J, et al.: Abacavir-lamivudinezidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial JAMA 2001, 285:1155-1163 Abstract ... interaction Nonthymidine-Containing ("TAM-Sparing") t-NRTI Regimens as Initial ART Clinical trials that have investigated the use of TDF as part of the NRTI backbone of an ART regimen among treatment-naive ... 27 Ruane P, Mendonca J, Timerman A, et al.: Kaletra vs nelfinavir in antiretroviral-naive subjects: Week 60 comparison in a phase III, blinded, randomized clinical trial Program and abstracts...
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How to Draw a Caricature in Profile potx
Ngày tải lên :
28/06/2014, 21:20
... the hair To draw the ear all you need to is make a curve similar to a backwards "C" shape and then inside that shape draw something that resembles a "D." There are many different ways to draw the ... drawing a woman this upper left definition is essential Add a straight line to the end of this line to show the natural line that happens when someone smiles Draw a slightly curved line to show ... not appear to be too small on the back of the head When you're just starting out learning how to draw a caricature I strongly suggest using a reference point for the back of the head The Hair and...
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Báo cáo y học: "Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases" pdf
Ngày tải lên :
09/08/2014, 06:22
... have utility in disease states beyond atherogenesis Sparrow and colleagues demonstrated that simvastatin had a comparable antiinflammatory effect to that of indomethacin in the carrageenan-induced ... studies are emerging In a murine model of allergic asthma, we recently showed potential benefits of statin therapy on inflammatory airway disease After priming and intra-nasal ovalbumin challenge, ... reductions in inflammatory cell infiltrate and eosinophilia in bronchoalveolar lavage fluid were observed with both oral and intraperitoneal administration of simvastatin [36] Continuing studies are addressing...
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Báo cáo y học: "Endogenous and exogenous stem cells: a role in lung repair and use in airway tissue engineering and transplantation" pdf
Ngày tải lên :
10/08/2014, 05:21
... Komura M, Komura H, Kanamori Y, Tanaka Y, Suzuki K, Sugiyama M, Nakahara S, Kawashima H, Hatanaka A, Hoshi K, Ikada Y, Tabata Y, Iwanaka T: An animal model study for tissue-engineered trachea fabricated ... 82 Omori K, Tada Y, Suzuki T, Nomoto Y, Matsuzuka T, Kobayashi K, Nakamura T, Kanemaru S, Yamashita M, Asato R: Clinical application of in situ tissue engineering using a scaffolding technique ... trachea containing the extracellular cartilaginous matrix [71] The experience with the engineered pig trachea was then used in engineering human trachea produced after dissemination of cartilage-like...
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báo cáo khoa học: "Regulation of cell cycle transition and induction of apoptosis in HL-60 leukemia cells by lipoic acid: role in cancer prevention and therapy" ppt
Ngày tải lên :
10/08/2014, 22:20
... induction of apoptosis was obtained by biochemical analysis showing that PARP cleavage was substantially increased in cells treated for 48 h with increasing doses of LA (Fig 3B) As addi- Figure bax/bcl-2 ... overall feasibility of using LA as a dietary supplement [3] In recent years, LA has gained considerable attention in the cancer field as an anticancer agent [14,15] Results from antiproliferation ... observed as early as 24 h, whereas cytochrome c release and nuclear accumulation occurred at 48 h Recent studies have demonstrated that AIF plays a critical role in caspase-independent induction of apoptosis...
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