... maximum rate of glucose consumption [MRGluc MAX ] by multiplying K i and (K M + [glucose] ), where K M is a half-saturation Michaelis constant for glucose uptake. Results were computed for 112 separate ... blood glucose levels, for example the Akt inhibitors [1], and sought a metric of tumor glucose uptake that had minimal glucose bias. Inverse correlations of blood glucose with tumor FDG uptake ... are highly glucose- addicted, glucose uptake capacity may well be a more important tissue characteristic to consider than the glucose uptake rate. MRGluc MAX reduces glucose bias by emphasizing
Ngày tải lên: 21/06/2014, 17:20
... probucol (pCRLPs) on the uptake of the particles by the cells, intracellular lipid synthesis, and the expression of mRNA for genes believed to play a part in foam cell formation, including those ... density of 3–9 · 105 cells per mL at 37 °C in 5% air/95% CO2 The cells were induced to differentiate into macrophages by incubation for 72 h in the presence of PMA (200 ngỈmL)1) Then, cells adhering ... 48 h before the cells were harvested and their lipid content determined For uptake studies, DiI-labelled CRLPs or pCRLPs (30 lgỈmL)1 cholesterol) were incubated with THP-1 macrophages for various
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells pdf
... should promote glucose consumption by the cells, we checked the effect of DIF-1 on glucose uptake in confluent 3T3-L1 cells (Fig 3C,D) The cellular activity of the 2-deoxy -glucose uptake was promoted ... for the glucose uptake promoted by DIF-1 to reach a maximum rate (Fig 3C) DIF-1 promotes glucose uptake in mammalian cells Thus, to obtain reliable and comparable data for the rates of glucose ... insulin on glucose uptake in 3T3-L1 adipocytes As shown in Fig 9A, DIF-1, as well as insulin, promoted the glucose uptake by two to three-fold However, while the insulin-promoted glucose uptake and
Ngày tải lên: 23/03/2014, 09:20
Báo cáo khoa học: " Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial pithelial cells" pot
... apoptosis Apoptosis was determined by staining the cells with annexin V for phosphatidylserine (PS) exposure and propidium iodide (PI) for cell permeability. Cells were incubated on ice with cold ... treated with 50, 100, and 200 µ M of NNK for 2 hrs with/without rapamycin pretreatment. For concentration-dependent study, cells were treated with 200 mM of NNK for 4, 12, and 24 hrs with/without rapamycin. ... Therefore, selective cap-independent translation can be produced in rapamycin-treated cells [2]. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone (NNK) is formed by
Ngày tải lên: 07/08/2014, 18:20
MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells
... miR-26a effects in glucose usage for colon cancer cells, the glucose uptake in HCT116 cells was compared either under the condition of miR-26a overexpression or inhibition The glucose consumption ... SW480 to SW620 cells The lactate content in NCM460 cells was much lower than each of CRC cells Especially for SW620 cells, it showed more than 5-fold of lactate production than NCM460 cells In combination ... Figure The miR-26a regulates glucose metabolism in HCT116 cells (A) Overexpression of miR-26a, by transfection of pENTR-miR-26a in HCT116 cells, elevated glucose uptake The empty vector pENTR-MIRNA
Ngày tải lên: 14/10/2020, 17:19
AgNi@ZnO nanorods grown on graphene as an anodic catalyst for direct glucose fuel cells
... [3,4] Currently, glucose has been exploited as a potential fuel in applications for enzymatic and direct fuel cells Enzymatic fuel cells utilizing glucose oxidation [5] and glucose dehydrogenase ... bio -glucose fuel cells [9,10] To date, some reported electrical power outputs have been performed using several direct glucose fuel cell (DGFC) types [5,7,11-15] It has been observed that glucose ... generation of fuel cells with non-Pt, low mass loading of catalyst, and 3D nanostructure electrodes for high electrochemical performances Keywords: 3D Nanostructures, CVD Graphene, Direct Glucose Fuel
Ngày tải lên: 22/11/2022, 14:09
inhibition of egf uptake by nephrotoxic antisense drugs in vitro and implications for preclinical safety profiling
... timedependent reduced uptake by the EGF receptor (EGFR) We further explored the regulation of EGFR transcriptional signature by tubulotoxic AONs M AN U RESULTS SC signaling by LNA-AONs and uncovered ... a growth factor for the cells, and 2) EP proximal tubule cells are known to express the EGF receptor (EGFR) and respond to EGF [18] More importantly, in vivo, EGF is produced by distal but not ... AON-free medium (scheme Fig 3d) EGF uptake and intracellular accumulation was visible in the form of green foci in vehicle-treated cells and was fully blocked by simultaneous incubation with Cetuximab,
Ngày tải lên: 04/12/2022, 14:59
Some suggestions for correcting errors made by english non major first year students at HPU of pronouncing ending sounds
... Miss Nguyen Quynh Hoa from Foreign Language Department for her help and encouragement My sincere thank also goes to Ms Tran Ngoc Lien, Dean of Foreign Language Department for her permission to take ... views, new directions Alexandria, VA: TESOL Oxford Advance Learner’s Encyclopedic Oxford University Press 10 Oxford Advanced Learner’s Dictionary.(2008) Oxford University Press 11 Roach,P.(2000) English ... pronunciation Oxford University Press Collins English Dictionary.(2003) HarperCollins Dulay, Burt and Krashen.(1982) Language Two Oxford University Press Ellis, R.(1997) Second Language Acquisition Oxford
Ngày tải lên: 17/12/2013, 20:37
Strategies for learning english writing by 10th form students at high schools = các chiến lược ngôn ngữ được ứng dụng trong việc học môn viết tiếng anh cho học sinh lớp 10 tại các trường THPT
... of foreign languages for their supports in providing with constructive suggestions for this thesis. I would like to thank the students at Nguyen Xuan On high school for their impartial help by ... university department of foreign language ------------------------------------------------ vơng thị thu hiền Graduation thesis strategies for Learning english writing by 10 TH FORM students at high ... better writer in English. For the above- mentioned reasons, the author is encouraged to undertake the study entitled" Strategies for learning English writing by 10 th form students at high schools"
Ngày tải lên: 20/12/2013, 18:33
21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx
... support without endless form-filling and waiting Reforming delivery Our ideas for structural reform have significant implications for the way support is delivered and for how individuals interact ... Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty July 2010 Cm 7913 £14.75 21st Century Welfare Presented to Parliament by the Secretary of State for Work and ... report All information contained in your response may be subject to publication or disclosure if requested under the Freedom of Information Act 2000 By providing personal information for the purposes
Ngày tải lên: 06/03/2014, 08:20
A Business and Co-operative Future For Weaver Street Market By Geoffrey Gilson docx
... the appropriate senior management present at each open forum, so that matters raised could immediately be addressed by those responsible for resolving them. My theme throughout this document, ... learned useful practices... Owner Programs, the open forums, the Marketing Messenger, the WSM Newsletter, the local media (both formal and informal – forums and blogs) and special meetings of ... responsiveness and accountability works best – namely, “Informal Intimacy.” “Informal Intimacy”: The Essence of Co-operation Look, I could jabber on for pages about charts, and lines of responsiveness
Ngày tải lên: 06/03/2014, 14:21
Báo cáo khoa học: Haptoglobin binds the antiatherogenic protein apolipoprotein E – impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes pdf
... factor for ApoA-I and ApoE function or a proatherogenic agent during the acute phase. Fig. 9. Effect of Hpt on the uptake of ApoE-containing or ApoA-I- containing liposomes by HepG2 cells. HepG2 cells ... way by which inflammation worsens the onset and the rate of progression of atherosclerosis. We evaluated the negative effects of Hpt on LCAT activity and cholesterol uptake by hepatocytes by using molar ... 37 °C with the primary antibody for 1 h, and then with the secondary antibody for 1 h. Goat anti-ApoE IgG followed by rabbit anti-goat HRP-conjugated IgG was used for detection of blotted ApoE,
Ngày tải lên: 07/03/2014, 00:20
IN THIS ISSUE: LIABILITY VS EQUITY CLASSIFICATION FOR FINANCIAL INSTRUMENTS ISSUED BY INVESTMENT FUNDS doc
... (ii) met for the whole instrument? Is the definition of (i) (ii) met for the whole compound instrument? or Is definition (ii) met the entire liability component? for Is definition (ii) met for part of ... Ye s No 5 IFRS for Investment Funds | 5 © 2012 KPMG IFRG Limited, a UK company, limited by guarantee. All rights reserved. Conditions required for equity classification Required for puttable instruments? Required ... entity Instruments issued by the sub-funds are assessed for equity classification from the perspective of the umbrella fund structure as a whole. Instruments issued by each sub-fund cannot qualify for equity
Ngày tải lên: 07/03/2014, 16:20
Báo cáo Y học: Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N -acyl-D-amino acid amidohydrolase responsible for D-amino acid production pdf
... at 37 °C overnight The transformants were screened for enzyme activity by adding to each well 10 lL mgỈmL)1 lysozyme and incubating at 37 °C for 30 This was followed by the addition 110 lL 25 mM ... coli A DNA fragment coding for the N-D-AAase was obtained by PCR using the Pfu DNA polymerase (Promega) PCR amplification was carried out as follows: 94 °C for followed by 30 cycles of 30 s at 94 ... activity was defined as the formation of lmol )1 D-methioninmin SDS/PAGE and Western analysis The proteins were separated by SDS/PAGE (10% acrylamide) as described by Laemmli [41] For Western blotting,
Ngày tải lên: 08/03/2014, 16:20
For Young Women Only by Shaunti Feldhahn and Lisa A. Rice potx
... 30356 © 2006 by Veritas Enterprises, Inc International Standard Book Number: 1-59052-650-3 Cover design by StudioGearbox.com Cover photo by Robin Nelson Interior design and typeset by Katherine ... retrieval system, or transmitted, in any form or by any means—electronic, mechanical, photocopying, recording, or otherwise—without prior written permission For information: MULTNOMAH PUBLISHERS 12265 ... FYWO.intr.fnl2 7/22/08 8:44 AM Page Excerpted from For Young Women Only by Shaunti Feldhan and Lisa Rice Copyright © 2006 by Veritas Enterprises, Inc Excerpted by permission of Multnomah Books, a division
Ngày tải lên: 14/03/2014, 18:20
Báo cáo khoa học: The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi potx
... WÆm )2 for different times before mycelia filtration. For carotenoid analysis of the strains used in the expression experiments, incubations were per- formed for 7 days in the dark at 22 °C. For ... with that of any formerly known carotenoid in Fusarium. The TLC carotenoid pattern for the three strains was confirmed by HPLC. T3 and T4 exhibited identi- cal profiles (results for T3 are displayed ... evi- dence for this function, transformation experiments were carried out to obtain null carD mutants of F. fujikuroi by targeted gene replacement with a hygromycin resistance cassette (Fig. 6A). For
Ngày tải lên: 14/03/2014, 22:20
Effects of compost and phosphate amendments on arsenic mobility in soils and arsenic uptake by the hyper
... favorable for the conversion of As (V) to the mobile As (III), thereby facilitating As uptake by the fern. In contrast, As adsorption onto organic matter applied in acidic soil may be responsible for ... As-contaminated soils, by increasing As uptake and decreasing As leaching. Published by Elsevier Ltd. Keywords: Phosphate; Biosolid compost; Municipal solid waste; Arsenic mobility; Arsenic uptake; Chinese ... capability of Chinese brake fern reported by Ma et al. (2001). The PR treatment enhanced As uptake by the Chinese brake fern, with frond concentrations increasing by 256% and 15.4% in the CCA and ASC
Ngày tải lên: 16/03/2014, 00:07
Effects of ph on cd and zn uptake by plant
... data were tested for homogeneity of variance by the log- anova test and for normality by the Kol- mogorov– Smirnov test for goodness of fit. Significance levels of tests are indicated by aster- isks ... respectively for cadmium and zinc) uptake is still relatively high. An explanation for this relative high metal uptake at pH 10.0 might be that an increase in pH alters the metal uptake process by decreasing ... re- gression analysis for cadmium uptake by midge larvae. Relating cadmium uptake to the free cad- mium ion activity describes only 6% of the total variation in cadmium uptake. When the term
Ngày tải lên: 16/03/2014, 00:07
Báo cáo khoa học: Structural basis for recognition of Co2+ by RNA aptamers pot
... of Co 2+ ; L, formamide ladder; T1, limited hydrolysis by RNase T 1 . Guanine residues are labeled on the right. Sites of interference are denoted with arrows. Recognition of Co 2+ by RNA aptamers ... propagate to nucleotides involved in the formation of the helix. The strong preference for the 5 ¢-side of the loops in comparison with the 3 ¢ -side may be explained by different sequences of both sides. ... necessary for enzyme activity (Fig. 8). The inhibition constants, determined as the concentration of Co 2+ at which the extent of RNase H digestion was reduced by half, were approximately 0.5 mm for
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation pdf
... activation by the thrombin-thrombo- modulin complex [6]. Activated protein C (APC) exerts its anticoagulant activity by inactivating factors Va (FVa) and VIIIa by limited proteolysis, thereby attenuating ... nm for QGNSEDY) for endothelial cell surface activation by thrombin. Interestingly, these vari- ants had greatly reduced (R9H) or greatly enhanced (QGNSEDY) ability to inactivate FVa. Therefore, ... characterized by slight increases in the V max for this reaction, with the increase for QGNSEDY being approximately twofold (Fig. 1A, Table 1). To further investigate this, the activation of QGNSEDY by
Ngày tải lên: 16/03/2014, 18:20