history and evolution of the computer mouse

... and Lacy [6] and is the mean of the kinship coefficients between that individ- ual and all candidates, including the individual itself. Candidates are defined as reproductive individuals of the ... Icelandic Sheepdog, just three of the 36 founders contributed more than 80% of the alleles of the current population (results not shown). In other words, in about 80% of cases, the pedi- gree of ... of Scandinavia and contains 85% of the total population size. It includes the entire Norwegian and Finnish populations and almost every animal born in Sweden or Denmark, and a large part of the

Ngày tải lên: 14/08/2014, 13:21

... contributes to a better understanding of the mechanisms of evolution and biological functions of the S100 gene family. 2. MATERIALS AND METHODS 2.1. Sequences and positions on the chromosomes or assembly ... of Fig. 2). Differences in the arrangement of the S100A genes were observed between the opossum and the other species examined, i.e. SG1 ( S100A10 and 11) together with S100A1 is located at the ... located at the 3 0 end of opossum chromosome 2 and at the 5 0 end of the corresponding chromosomes in the other s pecies (Fig. 1). Also, in the opossum, the positions of S100A9 and S10012 are reversed

Ngày tải lên: 14/08/2014, 13:22

... the genesis of various schemes of investments; and 4) the expansion in scope of enforcement activities. The resultant effect of the implementation of these developments was the expansion of the bureaucratic ... December 1953, the date of the enactment of the Ordinance.”9 With these rushed amendments passed, the CPF came into implementation on the 1 July 1955, and the state had a foot in the door for the social ... burden to others and the State.”89 The genesis of the rationalities for rescinding and restricting the right for complete withdrawals of CPF savings at the age of 55 can be found in the controversial

Ngày tải lên: 16/10/2015, 15:36

... by the Mayor In order to carry out each of these functions, the ordinance creates the position of the Civil Rights Administrator The position, appointed by the Mayor of the city, would hold the ... consider the ordinary and usual meaning of the language, and to insert the language requested by the State into the statute · where the plain language reads otherwise is beyond the scope of this ... in state law and, therefore, the ordinance does not violate the plain meaning of the language used in the first prong of Act 137 Second Prong of Act 137 The State ':lrgues that the word "basis"

Ngày tải lên: 11/01/2020, 17:03

... by the Mayor In order to carry out each of these functions, the ordinance creates the position of the Civil Rights Administrator The position, appointed by the Mayor of the city, would hold the ... consider the ordinary and usual meaning of the language, and to insert the language requested by the State into the statute · where the plain language reads otherwise is beyond the scope of this ... in state law and, therefore, the ordinance does not violate the plain meaning of the language used in the first prong of Act 137 Second Prong of Act 137 The State ':lrgues that the word "basis"

Ngày tải lên: 13/01/2020, 03:15

... northern contact of the EPC, which have representative ore and gangue paragenesis for the mineralization of the northern contact In these deposits we describe the presence of changing redox conditions ... the EPC and 10 of them were selected, based on their location near the mineralization sites In the QAP molecular normative diagram (Streckeisen 1976), the rocks plot in the monzogranite and granodiorite ... skarn Aplitic dykes of the EPC cross-cut plutonic rocks associated with magnetite deposits at the eastern and southern contacts, whereas in the centre and northern part of the pluton, dykes are

Ngày tải lên: 13/01/2020, 14:48

... Mercian The speech of eastern and northern parts of England was subject to strong Old Norse influence due to Scandinavian rule and settlement beginning in the 9th century Old English is one of the ... number of speakers, plus its worldwide presence, have made English a common language ("lingua franca") "of the airlines, of the sea and shipping, of computer technology, of science and indeed of ... language by number of speakers, and the third mostspoken native language in the world, after Standard Chinese and Spanish It is the most widely learned second language and is either the official language

Ngày tải lên: 21/12/2021, 10:23

... the rest of the world This is part of the reason why people believe English will be the Universal Language of the future Aim of the study Old English, Middle English, and Modern English are the ... habitats and their style of speech which include vocabulary, accent, and even the structure of the language This briefly discussion will be structured around the internal history of the English ... century, the transition from Middle English to Modern English began Much of the transition was due to the expansion of the British Empire throughout the world and to the development of printing The

Ngày tải lên: 21/12/2021, 10:23

... place the MOOC in a sociohistorical context and develop subsequent research questions and instruments to study the model-cumphenomenon THE HISTORY OF THE FIRST MOOCS Tracing the history of the ... creation and development of the disciplines This difference is echoed in the work of Garrison (2009), who sees the history of distance education as supporting the passivity of the learner rather ... activating the learner through the use of telecommunications: The theory and practice of distance education appears to continue to hold to the assumptions and challenges that defined the field in the

Ngày tải lên: 27/10/2022, 17:47

... bottom line and corresponds to the length of the branches Each of the branches has been colour coded corresponding to the place of origin of each of the taxa In the first tree southern African ... strains from the start of the epidemic and applied phylodynamic techniques to determine the history of the southern Africa and South African epidemic from longitudinal sampled data The southern African ... during the 1970s and 1980s for the southern African epidemic The exponential growth of the Ne observed during the 1970s and 1980s for the southern African region is in accordance with the high

Ngày tải lên: 04/12/2022, 10:38

... knowledge of the arts and stratagems of war, but they confessed the strength and courage of the French cavalry, and the infantry of the Germans; ^15 and the strangers are described as an iron race, of Part ... to the humble appellation of Rex, or prince, of the Alemanni; and the vain and feeble Angelus affected to be ignorant of the name of one of the greatest men and monarchs of the age. While they ... sent the hair of his women, a sad emblem of their grief and terror, to excite the pity of the sultan of Damascus By the command of Noureddin, and the sentence of the

Ngày tải lên: 08/03/2014, 18:20

... this book we give an overview of the various areas of software visu- alization, the art and science of generating visual representations of various aspects of software and its development process. ... (Revisited) Further Reading and Resources The Future of Software Visualization Fig 1.2 Organization of this book Chapter 5 covers the visualization of software evolution The techniques ... managers of large software projects need tools to get a quick overview of the state of the whole system, and to find trends in the evolution of the system SeeSoft was developed

Ngày tải lên: 03/07/2014, 21:10

... to the improvement of quality and efficiency of such cooperation in the future  Outcomes of the thesis shall contribute to the research and teaching of the history of the Communist Party of ... process, the Ministry of Education and Training identified the means to increase the scale and the efficiency of international integration of the 2000-2005 period Implementing the mandate of the 6th ... 8th, 2002 on the promulgation of the action plan of the educational field regarding the mandate of the 6th plenum of the 9th Central Committee term and the educational strategy for the 21 2001-2010

Ngày tải lên: 14/07/2014, 13:23

... little is known about the role of humoral immunity in the evolution of the HIV-2 env gene In the present study we analyze, for the first time, the molecular evolution of the env C2V3C3 regions ... investigate, for the first time, the short-term molecular evolution of the HIV-2 C2, V3 and C3 envelope regions and its association with the immune response Clonal sequences of the env C2V3C3 region ... diversity of the C2V3C3 region Variation of the C2V3C3-specific IgA response was inversely associated with variation in the number of N-glycosylation sites Conclusion: The evolutionary dynamics of HIV-2

Ngày tải lên: 13/08/2014, 05:21

... which the initial L593Q change destabilizes the gp120-gp41 interac- tion. Of note is that the crystal structure of the SIV ectodo- main places the side chain of residue 593 on the outside of the ... carried out the initial replication and evolution experiments and drafted the manuscript. MMD carried out part of the evolution experiments and constructed the molecular clones containing the revertant ... is purple. The side chains in fig. C and D, use the same color scheme. Panels A and C depict a side view of the gp41 loop region, panels B and D a top view from the perspective of the target

Ngày tải lên: 13/08/2014, 13:20

... assessments of core- genome were estimates of the pangenome size of each of these groups, and levels of gene gain, loss and duplication on each of the lineages reviews In the ... of the p value heatmap (Figure 5a) and bipartition analyses (Figure 5b). A majority of the genes (around 150 out of 260) show no conflict with each other. Most of them support the monophyly of ... monophyly of the different species and the lineage S. pneumoniae + S. suis, and most of them do not reject the concatenated gene tree. Another set of genes showed some instances of conflict with the aforemen-

Ngày tải lên: 14/08/2014, 07:21

... conditional to the transmission of the QTL Transmission of the QTL was conditional on the phenotype of the offspring and on the QTL genotypes of the parents In that case, we used the Bayes theorem: ... areas, we decided to compare the evolution of microsatellites from the Aviandiv panel (European project on the analysis of diversity in the chicken) and the evolution of microsatellites located ... Goldringer I., Verrier E., On the need of combining complementary analyses to assess the effect of a candidate gene and the evolution of its polymorphism: the example of the Major Histocompatibility

Ngày tải lên: 14/08/2014, 13:21

... beginning of the new century The globalization of finance that took root and expanded during the last quarter of the twentieth century was the natural accompaniment of the growth ... the collapse of the Bretton Woods system in the early 1970s, the international debt crises of the 1980s, and the financial crises of emerging market economies of the ... the end of the book, which provides a brief summary description of each of the committees, groups, and institutions that make up the IFA Key Themes of the Book Many themes are

Ngày tải lên: 01/11/2014, 17:01

... compares the studied network with randomized versions of it with the same size and degree dis- tribution. The so-called Z-score quantifies the difference between the studied network and an ensemble of ... analysis of the topological modules of the Fig. 3 (labelled A–G) shows that they include structural and ⁄or functional features. Table 3 summarizes the main structural and functional features of these groups. ... functions, and topologi- cal features retain functionality and phylogeny. How- ever, the nature of the connections between these factors needs to be understood at the level of the pro- tein domain. The...

Ngày tải lên: 19/02/2014, 07:20

... of the water from this bulb decreases the temperature of the mercury in the tube b in proportion to the dryness of the atmosphere, and the number of degrees the tube b indicates below that of the ... it on the decanter, and lay it in the sun's rays in such a manner that the rays may pass through the spaces cut out of the paper and fall on the surface of the liquor the part of the glass ... Drawing and painting being the natural bent of his mind, be was frequently employed by the professors to make landscape sketches in the manner mentioned. The beauty of the image of these landscapes...

Ngày tải lên: 22/02/2014, 03:20