... Results Quantitative analysis of membrane proteins from paired tumoral and adjacent normal tissue of CRC patients A total of eight tumor tissues and eight matched normal tissues were collected ... and molecular function (Fig 3) To better understand the probable roles of the membrane proteomes in terms of their biological functions, the subcellular localization and molecular functions of ... HLA-A1, SLC25A4 and TAPBP The results of the western blot analysis in the tumoral andnormal tissues confirmed the LC-MS ⁄ MS results The expression 3032 levels of CLDN3, HLA-A1 and SLC25A4 were...
... modularization of the system of interest and subsequent application of modular kinetic analysis allows identification of molecular targets of Cd2+ and Cu2+ ions In the first application of the analysis, ... analysis and MCA to determine the effects of low concentrations (5 lm) of CdCl2 and CuCl2 on the kinetics and control of oxidative phosphorylation in isolated rat liver mitochondria respiring on succinate ... noted that the effects of Cd2+ and Cu2+ ions were determined in two separate series of experiments (performed in spring and autumn, respectively) resulting in two sets of flux and Dw values under...
... Pandy MG: Computer modeling and simulation of human movement Annu Rev Biomed Eng 2001, 3:245-273 Shelburne KB, Pandy MG, Anderson FC, Torry MR: Pattern of anterior cruciate ligament force in normal ... The influence of muscles on knee flexion during the swing phase of gait J Biomech 1996, 29:723-733 Anderson FC, Goldberg SR, Pandy MG, Delp SL: Contributions of muscle forces and toe-off kinematics ... differentiate between the roles of gastrocnemius and soleus during the stance phase ofnormal walking Though these muscles are often grouped together functionally as plantarflexors of the ankle, important...
... Onouchi and Akira Hata Chapter The Role of Proteinase and Neutrophils in ANCA-Associated Systemic Vasculitis 93 Mohamed Abdgawad Part Pathogenesis andPathologyof Vasculitis 113 Chapter Pathologyof ... vasculitis and how some antibodies may become pathogenic The following section deals on the pathologyof vasculitis and the potential role of endothelial cells and cytokines in vascular damage and repair ... expression represents the ratio of the number of copy of mRNA of interest versus mRNA of GAPDH All calculations were done using the 2CT model of (Pfaffl, 2001) and experiments were performed according...
... in the field of the pathologyof the head and neck As such they are the main members of the Working Group on Pathologyof the Head and Neck of the European Society of Pathology, one of the first ... Gerhard Seifert and to Leslie Michaels, great pioneers of Head and Neck Pathology in Europe and founding members of the Working Group on Head and Neck Pathologyof the European Society ofPathology ... salivary glands, nasopharynx and Waldeyer`s ring, larynx and hypopharynx, ear and temporal bone, neck and neck dissection, as well as eye and ocular adnexa The pathologyof the thyroid and parathyroid...
... bands at ∼1,460 and ∼1,400 cm could be ascribed to the in-plane bending vibrations of CH3 On the other hand, the vibrational bands at ∼1,235 and ∼1,085 Characterization ofnormaland lung cancer ... were normalized with respect to that of the amide I band at ∼1,650 cm 1 Table Spectral data and vibrational assignments ofnormaland lung cancer cells* Normal cells † (NHBE ) Cancer cells (NCI-H358) ... Infrared spectra of lung cancer cells The infrared spectra of lung cancer cells were recorded as shown in Figs 1b and c It is noteworthy that the νs(PO32) and νs(PO2 ), bands at ∼970 and ∼1,085 cm...
... dosimetric techniques allow estimation of the tumor andliver radiation doses [18] The extent of resection ofliver metastases is restricted by the volume of the future liver remnant (FLR) Among different ... tumors, and its indications have been subsequently extended to patients with metastatic liver tumors [3-9] Induction of hypertrophy of the nondiseased portion of the liver reduces the risk of hepatic ... goal of increasing the volume of the FLR [2] First reported by Makuuchi et al [3], the aim of PVE is to bring about atrophy of the segments to be resected and induce a compensatory hypertrophy of...
... weights and ages of the patients were normally distributed and thus compared with the calculation of means and Student t tests The weight of the articular cartilage samples and quantity of RNA ... calculations of means, standard deviations, and fold changes from normaland paired twotailed t tests (body weight and age) performed in a spreadsheet program (Microsoft Excel 2003; Microsoft Corporation, ... Figures and 2, with all data normalised to the mean of the control values (with a fold change of being no change, a fold change of meaning a doubling of expression, and a fold change of 0.5 meaning...
... associations of between IMRT plans and dose relationships Results Tumour/planning characteristics Eleven patients with primary liver cancer and sixteen with liver metastases having a total of 45 liver ... beam segments in liver IMRT The aim of this study was to determine the minimum number of planned segments in liver IMRT plans that could maintain adequate target coverage andnormal tissue dose ... volume ofnormalliver irradiated to minimise the risk of radiation induced liver disease, however other beam angles are also chosen to create steep radiation gradients near adjacent normal visceral...
... cc and 30 cc of the whole heart volume (the D20 and D30 respectively) was measured The volume of the heart receiving a dose of Gy and higher, 10 Gy and higher and 20 Gy and higher (V5, V10 and ... balloon and surrounding critical normal tissues Axial CT Axial CT images demonstrating the isodose pattern of the MammoSite balloon and surrounding critical normal tissues In the absence of intravenous ... and as a percentage of the total cardiac volume The highest dose received by cc (D5) of the ipsilateral lung was measured The volume of the ipsilateral lung receiving a dose of 10 Gy, 20 Gy and...
... reports of resected cancers, liver ultrasound and x-ray of the thorax Locoregional tumor extention was studied by MRT in all cases Delineation of target volumes andnormal tissues Immobilisation of ... irradiation of the neck and the oro- and nasopharynx Pretreatment evaluation consisted of a complete history and physical examination including endoscopy in unresectable cancers and detailed surgical and ... margin The mandible and oral cavity were not delineated routinely Treatment planning and delivery In patients with tumors of the nasopharynx, the oropharynx, the oral cavity or floor of mouth the...
... reduction) of wind-up scores in the MP group 20 and 40 minutes Figure Effect of IL-1β on C-reflex integrated activity in propentofylline -and saline-treated normaland monoarthritic rats (NS, MS, NP, and ... propentofylline- and saline-treated normaland monoarthritic rats (NS, MS, NP and MP groups) (a) groups) Time course of wind-up scores (% change) 10, 20 and 40 minutes after administration of saline ... standard laboratory conditions and were given food and water ad libitum With the purpose of knowing the monoarthritic and hyperalgesic condition of the rats, we measured the circumference of...
... designed to verify how normaland transformed cell lines respond to exposure to modeled microgravity We therefore used two normal, LB and HSC93, and two transformed, Jurkat and 1310, lymphoblast ... exposure Page of 10 Methods Cell lines, Proliferation and Apoptosis Lymphoblast cell lines LB and HSC93 are normal B and T, respectively, human lymphocytes immortalised with EBV Jurkat and 1310 are ... frames and the platform are driven by means of belts and two electro-motors The RPM is computer managed and a dedicated software permits the settings for modeled microgravity at the value of choice...
... EL and HA: carried out the immunofluorescence assays and drafted the manuscript; JLB and MS: conceived the envelope-derived tagged ligands while; JLB, HA, ML and JT: generated, optimized and ... al.: Regional characterization of energy metabolism in the brain ofnormaland MPTP-intoxicated mice using new markers of glucose and phosphate transport Journal of Biomedical Science 2010 17:91 ... step-size of μm with a specimen magnification of 100× Deconvolution was performed through Huygens professional software (Scientific Volume Imaging, Hilversum, The Netherlands) with 0% background offset...
... The influence of footwear on the prevalence of flat foot A survey of 2300 children J Bone Joint Surg Br 1992, 74:525-7 Page of (page number not for citation purposes) Journal of Foot and Ankle Research ... tuberosity and the line between the markers on calcaneus and first metatarsal head The distance between the floor and the line in standing position between the markers on calcaneus and first metatarsal ... (Table 2) 95% of the population had an ND less than 8.7 mm and greater than 1.7 mm Approximately the same mean ND was observed among women and men (5.2 and 5.3 mm respectively) BMI and age were...
... pattern of expression, that is high expression of ACAN in NP and AC, high expression of type I collagen in AF compared with NP and AC, and high expression of versican (VCAN) in both NP and AF ... or protein profiles of IVD cells and AC cells Hypoxia inducible factor isoforms (HIF1A and HIF1B), glucose transporter type Page of 20 (GLUT-1), matrix metalloproteinase (MMP-2) and vascular ... (FOXF1), and fibulin (FBLN1)) and the chondrogenic marker genes (aggrecan (ACAN) and type II collagen (COL2A1)), was normalised to the housekeeping gene andnormal annulus fibrosus (AF) or NP cells and...
... through a bundle of optical microfibres to the tip of the miniprobe of mm in diameter, which can be inserted into the working channel of a fibreoptic bronchoscope [14] High-quality and real-time ... Lung, and Blood Institute (NHLBI) and the National Institute of Allergy and Infectious Diseases (NIAID) [19] Participants received local anaesthetic by Lignocaine 1% and 10% spray in the nose and ... elastic fibre pattern between histologyand FCFM (weighted kappa w 0.744, Table and 3) There was only discrepancy between histologyand FCFM in the classification of the patterns into scores or...
... clinical research of the University Hospitals of Lyon andof the French Ministries of Health andof Research, and all patients gave their informed written consent Patients and disease controls ... composition of the inflammatory infiltrates, especially the presence of plasma cells and/ or eosinophils; presence, extent and distribution of hepatocellular necrosis; presence, extent and distribution of ... systematic liver biopsies prior to the introduction of long-course lowdose MTX and after year of therapy Eleven cases of hepatic fibrosis were observed prior to the introduction of MTX, with no sign of...