histologic types of ovarian cancer

báo cáo hóa học:" Differential hRad17 expression by histologic subtype of ovarian cancer" ppt

Ngày tải lên : 20/06/2014, 07:20

... different subtypes of ovarian cancer While only 42% (30/72) of papillary serous and 47% (9/19) of endometrioid subtypes showed over-expression, 80% (8/10) of clear cell and 100% (6/6) of mucinous ... over-expressed in ovarian cancer, as seen in breast, colon, and lung cancer Further, the pattern of expression differs among subtypes of ovarian epithelial cancers Unlike studies in breast and lung cancer ... over-expression of total and phosphorylated hRad17 protein in ovarian cancer cell lines compared to normal HOSE cell lines Three of four ovarian cancer cell lines were positive for over-expression of hRad17...

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Ovarian cancer: the recognition and initial management of ovarian cancer doc

Ngày tải lên : 22/03/2014, 16:21

... prior probability of undiagnosed ovarian cancer of 0.04% (Hamilton et al., 2009) 17 Ovarian cancer: the recognition and initial management of ovarian cancer Box 2.1 Definitions of terms used in ... (NPV) of a given symptom for ovarian cancer is the proportion of women without that symptom who not have ovarian cancer The positive predictive value of bloating as a symptom of ovarian cancer ... relationship between the duration of symptoms and ovarian cancer outcome 2.1 Awareness of symptoms and signs Early recognition of ovarian cancer symptoms Ovarian cancer has been termed ‘the silent...

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Frequency of Symptoms of Ovarian Cancer in Women Presenting to Primary Care Clinics potx

Ngày tải lên : 29/03/2014, 01:20

... among women with cancers of the ovary Cancer 1985;56:2727-2732 10 Goff BA, Mandel L, Muntz HG, Melancon CH Ovarian cancer diagnosis: results of a national ovarian cancer survey Cancer 2000;89:20682075 ... Table Women With Ovarian Cancer Compared With Those Without Ovarian Cancer OR (95% CI) Cancer vs Benign Ovarian Tumor Cancer vs Clinic Patients* Cancer vs IBS Patients Type of pain Pelvic Abdominal ... women with ovarian cancer with 151 women with ovarian tumors of low malignant potential In that study, symptoms were reported prior to diagnosis by 92% of women with invasive cancer and 86% of women...

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báo cáo hóa học:" Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer" pdf

Ngày tải lên : 18/06/2014, 15:20

... supporting the use of Alemtuzumab as a therapeutic agent for ovarian cancer patients Materials and methods Tissues Stage III epithelial ovarian cancer (n = 10), and ductal breast cancer specimens ... numbers of CD45+/VE-Cadherin+ VLC in stage III ovarian cancer solid tumors [21] We tested whether these cells are unique to ovarian cancer or whether they are present broadly in Co-immunofluorescence ... tumor growth in a murine model of ovarian cancer We next tested the impact of anti-CD52 antibody therapy on ovarian tumor growth in vivo using the ID8-VEGF murine ovarian flank tumor model As above,...

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báo cáo hóa học:" Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB" doc

Ngày tải lên : 20/06/2014, 07:20

... several cancers, including ovarian cancer [4-7] Moreover, mutations may be one of the major factors contributing to the origin of ovarian cancer stem cells Emerging evidence suggests that ovarian cancer ... resistance in ovarian cancer [3] Pretreatment of cisplatin resistant ovarian cancer cells Figure diagram agents chemo-therapeutic of potential mechanism of genistein induced chemo-sensitization of ovarian ... in ovarian cancer cells [20]; however the role of genistein in chemo-resistant ovarian cancer cells has not been investigated Therefore, the intent of this study was to evaluate the effect of...

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báo cáo hóa học:" Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients" pot

Ngày tải lên : 20/06/2014, 07:20

... were analyzed in this study: 21 cases of serous ovarian cancer, 22 cases of serous ovarian cancer metastatic to the omentum, 24 cases of serous ovarian cancer widely metastatic to other regions ... of Ovarian Research 2010, 3:21 http://www.ovarianresearch.com/content/3/1/21 Page of 14 Figure Expression of LRG1 transcripts in ovarian cancer tissues and cell lines A) Microarray analysis of ... low levels in the ovarian cancer tumor extracts and was present in the protein extracts of only a few of the ovarian cancer cell lines It is possible that this ~51 kD glycoform of LRG1 is secreted...

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báo cáo hóa học:" Gene Expression and Pathway Analysis of Ovarian Cancer Cells Selected for Resistance to Cisplatin, Paclitaxel, or Doxorubicin" docx

Ngày tải lên : 20/06/2014, 08:20

... ovarian cancer represents 3% of all the new cancer cases in women, but accounts for 5% of all the cancer deaths [1] This discrepancy is due, in part, to the common resistance of ovarian cancer ... lack of alternatives for the treatment of drug resistant disease are responsible for a 5-year survival of approximately 30% in ovarian cancer patients with advanced disease Indeed, 90% of the ... expression profiling to identify genes and pathways that may be important to the development of drug resistance in ovarian cancer Methods Cell line and generation of drug resistance sub-lines The ovarian...

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Báo cáo khoa học: "Intra-operative intra-peritoneal chemotherapy with cisplatin in patients with peritoneal carcinomatosis of ovarian cancer" pptx

Ngày tải lên : 09/08/2014, 04:21

... World Journal of Surgical Oncology 2009, 7:14 Background Ovarian cancer is the leading cause of gynaecologic cancer- related death in most industrialized countries and the fifth cause of cancer death ... sur- 15 16 Almadrones LA: Treatment advances in ovarian cancer Cancer Nurs 2003, 26:16S-20S Ozols RF: Update on the management of ovarian cancer Cancer J 2002, 8(Suppl 1):S22-30 Carmignani CP, ... treatment of ovarian cancer Cancer Treat Rep 1978, 62:1-11 Look M, Chang D, Sugarbaker PH: Long-term results of cytoreductive surgery for advanced and recurrent epithelial ovarian cancers and...

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Báo cáo khoa học: "Carbonic anhydrase XII expression is associated with histologic grade of cervical cancer and superior radiotherapy outcome" ppsx

Ngày tải lên : 09/08/2014, 09:20

... expression of CA12 in 183 invasive cervical cancers and investigated its possible correlation with conventional histologic differentiation The prognostic value of CA12 and histological grading of the ... with histologic grades of the cervical cancer As CA12 and histologic grade were significantly associated with each other, we then examined whether an application of combined categories of CA12 ... events was 26 months (range, 2-50) Page of 10 Histologic grade and immunohistochemical expression of CA12 in cervical cancer Tissue samples were composed of 2~4 pieces measuring approximately ×...

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báo cáo khoa học: " Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer" ppsx

Ngày tải lên : 10/08/2014, 10:20

... understand biological relevance of SULF1 SNPs in the development of ovarian cancer are needed to validate the role of SULF1 SNPs in age of disease onset and prognosis of ovarian cancer Acknowledgements ... European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl Cancer Inst 2000, 92:205-216 Lee LF, Hellendall ... development of cancer Although several studies reported that SULF1 expression was downregulated in different types of cancer [11-14], SULF1 was upregulated in gastric and pancreatic cancers [24,34]...

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Báo cáo y học: "Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report" ppsx

Ngày tải lên : 11/08/2014, 03:20

... natural history of ovarian cancer, the anatomical and physiological characteristics of the peritoneal cavity and liver, direct intra-peritoneal drug delivery could result in a profound increase ... improved quality of life On the basis of this study we formed a platform for the design of an extensive Phase I study on a larger number of human patients to test the safety of this treatment ... the DT-A gene under the control of H19 regulatory sequences; EOC: epithelial ovarian cancer; IHC: immunohistochemistry; ISH: in situ hybridization; OCAF: ovarian cancer ascites fluid; PCR: polymerase...

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Báo cáo y học: "A Randomized Study of Epithelial Ovarian Cancer: Is Chemotherapy Useful after Complete Remission"

Ngày tải lên : 03/11/2012, 09:57

... for ovarian cancer There were two cases of breast cancer, two cases of sigmoid adenocarcinoma, one case of small cell lung cancer, one case of hypernephroma, and one case of head and neck cancer ... survival in advanced ovarian cancer not vary in relation to the number of cycles of chemotherapy given, (6 vs cycles of PAC [Platinum-Adriamycin-Cyclophosphamide] [19], vs 10 cycles of polychemotherapy ... Fuks Z External radiotherapy of ovarian cancer: Standard approaches and new frontiers Semin Oncol 1975;2:253-266 Dembo AJ Radiotherapeutic management of ovarian cancer Semin Oncol 1984;11:238-250...

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Báo cáo khoa học: MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-jB1 ppt

Ngày tải lên : 07/03/2014, 00:20

... be markedly downregulated in ovarian cancers, and 5538 Fig Dysregulation of miR-9 in ovarian cancer tissues The miR-9 expression level of four pairs of human ovarian cancer tissue samples (Ca) ... MiR-9 inhibits ovarian cancer cell growth L.-M Guo et al Fig Dysregulation of NF-jB1 in ovarian cancer tissue samples The NF-jB1 expression level in the four pairs of human ovarian cancer tissue ... Facility of Tianjin Medical University Cancer Institute and Hospital and National Foundation of Cancer Research for providing human ovarian cancer samples We also thank the College of Public Health of...

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báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc

Ngày tải lên : 18/06/2014, 15:20

... a therapeutic vector for ovarian cancer The level of H19 transcript in human ovarian cancer cell lines We determined the level of H19 RNA in different human ovarian cancer cell lines Total RNA ... National Cancer Institute [http://www .cancer. gov /cancer topics /types/ ovarian] Cannistra SA: Cancer of the ovary N Engl J Med 2004, 351:2519-2529 McGonigle KF, Dudzinski MR: Endometrioid carcinoma of ... study on the expression profile of H19 in epithelial ovarian cancer [19] The therapeutic potential of the toxin vector was evaluated in vitro using different human ovarian cancer cell lines and in...

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Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt

Ngày tải lên : 18/06/2014, 16:20

... functions in the context of estrogen-related signalling in breast cancer and ovarian cancer The potential clinical relevance of this is however less evident as the beneficial effect of high RBM3 expression ... treatment of epithelial ovarian cancer Curr Treat Options Oncol 2009, 10:54-66 Tummala MK, McGuire WP: Recurrent ovarian cancer Clin Adv Hematol Oncol 2005, 3:723-736 Siddik ZH: Cisplatin: mode of cytotoxic ... molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome Clin Cancer Res 2008, 14:5198-5208 18 Bolstad BM, Irizarry RA, Astrand M, Speed TP: A comparison of normalization...

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Báo cáo sinh học: "Peritoneal carcinomatosis from ovarian cancer: chemosensitivity test and tissue markers as predictors of response to chemotherapy" doc

Ngày tải lên : 18/06/2014, 19:20

... vitro results Page of and clinical response was observed in 27 out of the 30 patients analyzed, with a predictivity of 85.7% in terms of sensitivity and of 91.3% in terms of resistance The important ... information of the case series Characteristics No patients Cancer Primary Recurrent 23 Histological type Serous Results of cytoreduction 30 CC0 15 CC1 CC2 Unresectable Peritoneal Cancer Index ... drug toxicity and lower the cost of health care In ovarian cancer, despite the heterogeneity of treatments available for peritoneal carcinomatosis, the majority of patients receive platinum-containing...

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o cáo hóa học:" Peritoneal carcinomatosis from ovarian cancer: chemosensitivity test and tissue markers as predictors of response to chemotherapy" doc

Ngày tải lên : 20/06/2014, 04:20

... vitro results Page of and clinical response was observed in 27 out of the 30 patients analyzed, with a predictivity of 85.7% in terms of sensitivity and of 91.3% in terms of resistance The important ... information of the case series Characteristics No patients Cancer Primary Recurrent 23 Histological type Serous Results of cytoreduction 30 CC0 15 CC1 CC2 Unresectable Peritoneal Cancer Index ... drug toxicity and lower the cost of health care In ovarian cancer, despite the heterogeneity of treatments available for peritoneal carcinomatosis, the majority of patients receive platinum-containing...

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báo cáo hóa học:" Can subjective global assessment of nutritional status predict survival in ovarian cancer?" pptx

Ngày tải lên : 20/06/2014, 07:20

... risk of chemotherapy-induced toxicity and a reduction in survival of cancer patients [11,12] ovarian cancer being no exception [13] The prevalence of malnutrition in patients with ovarian cancer ... Journal of Ovarian Research 2008, 1:5 http://www.ovarianresearch.com/content/1/1/5 ian cancer is the fifth leading cause of cancer deaths in women, the leading cause of death from gynecological ... N = 132 Page of (page number not for citation purposes) Journal of Ovarian Research 2008, 1:5 http://www.ovarianresearch.com/content/1/1/5 Table 4: Prognostic Classes of Ovarian Cancer Patients...

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báo cáo hóa học:" Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype" pptx

Ngày tải lên : 20/06/2014, 07:20

... progression of ovarian cancer Expression profiling of epithelial ovarian cancer of varying histologies has identified genetic signatures that distinguish the major histological types of ovarian carcinoma ... expression of miRNAs in cancer by microarray analysis miRNAs expression profiling can distinguish between different types of cancers and even between different subtypes of tumors from the same cancer ... the context of ovarian cancer Epigenetics of cancer stem cells Promotion and expansion of stem/progenitor cells predisposes cancer development by expanding a pluripotent population of cells that...

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báo cáo hóa học:" Enhancing the efficacy of cisplatin in ovarian cancer treatment – could arsenic have a role" potx

Ngày tải lên : 20/06/2014, 07:20

... platinum-resistant human ovarian cancer cell line CI80-13S and the platinum-sensitive human ovarian cancer cell line OVCAR They also appeared to slow the growth of the cisplatin-sensitive human ovarian cancer ... (MRP) is a member of a family of transport proteins that facilitates the extrusion of a variety of glutathione-coupled and unmodified drugs out of cells but over-expression of MRP alone does ... Journal of Ovarian Research 2009, 2:2 been made in the treatment of EOC, the enigma remains that a disease which is highly sensitive to chemotherapy compared to many other types of cancer is...

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