herb vegetable and fruit inhibit hemolysis and heinz body formation in human erythrocytes
Báo cáo khoa học: Transport of L-arginine and nitric oxide formation in human platelets pdf
Ngày tải lên :
08/03/2014, 02:20
... maximal inhibition, that Ó FEBS 2003 Arginine transport and NO formation in platelets (Eur J Biochem 270) 2007 Fig L-Arginine uptake in human platelets: sensitivity to N-ethylmaleimide and effect ... cationic amino acids lysine, arginine and ornithine at the basolateral membrane of the polar epithelial cells in the intestine and renal tubules LPI is caused by mutations in the SLC7A7 gene encoding ... in which the L-leucine effect was tested (B), L-leucine and L-arginine were added simultaneously After min, incubation was stopped and L-arginine uptake measured as described in Experimental procedures...
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Báo cáo khoa học: cGMP and glutathione-conjugate transport in human erythrocytes The roles of the multidrug resistance-associated proteins, MRP1, MRP4 and MRP5 pot
Ngày tải lên :
23/03/2014, 21:20
... producing 50% inhibition of the inhibitable component, U0 is the uptake in the absence of the inhibitor, Unoninh is the uptake which cannot be inhibited and ni is the Hill coefficient for the inhibitor ... Methotrexate and E217bG were found to inhibit the cGMP uptake in human erythrocyte vesicles with E217bG at 65 lM inhibiting about 90% and methotrexate inhibiting about 75% at 275 lM and completely ... transport in human erythrocytes (Eur J Biochem 270) 3705 Fig Immunodetection of MRP4 and MRP5 in human erythrocytes and COR-L23 cells Inside-out membrane vesicles prepared from human erythrocytes, ...
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Báo cáo y học: "Heat shock protein 70 expression, keratin phosphorylation and Mallory body formation in hepatocytes from griseofulvin-intoxicated mice" pptx
Ngày tải lên :
13/08/2014, 13:20
... during incubation step with secondary antibody For heat shock proteins staining, liver sections were incubated with anti-HSP 70i diluted in TBS containing 10% BSA for 45 at 37°C, washed in TBS and ... A and B indicate clusters of hepatocytes containing both K8 pS79 and K8 pS436 Note: reactivity in nuclei observed in A, B, C and D represents non-specific staining due to the secondary antibody ... treatment Arrows in A and B indicate cells in which HSP70i and K8 pS79 colocalized Arrows in C and D indicate cells in which HSP70i and K8 pS436 colocalized Scale bar = 20 µm keratin phosphoepitope...
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3D Videocommunication Algorithms concepts and real time systems in human centred communication
Ngày tải lên :
12/05/2013, 10:21
... paintings had been a well-known phenomenon since Roman times, and such paintings would create the illusion of, for instance, walls containing a window to the outside world or a ceiling containing ... rendering Image cube trajectory Institute of Electrical and Electronics Engineers Internet Engineering Task Force Interaural intensity difference Interaural level difference Infrared light-emitting ... multidisciplinary perspective that integrates media design and engineering, multisensory perception, and social psychology Add to this the increasingly social nature of interfaces and the increase in...
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Báo cáo khoa học: Intrinsic disorder and coiled-coil formation in prostate apoptosis response factor 4 pptx
Ngày tải lên :
16/03/2014, 02:20
... C-terminal segment, including the androgen receptor [35], F-actin [36], 14-3-3 [26] and the SPRY domain-containing suppressor of cytokine signalling box proteins 1, and [37] Par-4 contains several ... efficient linker protein The majority of the Par-4 binding partners interact with the C-terminus, although a few, such as the SPRY domain and F-actin, have been shown to bind N-terminally [36,37] Indeed, ... post-translational modifications and a plethora of binding partners are characteristics common to many intrinsically disor- Intrinsic disorder in Par-4 dered proteins (IDPs) [39] In the present study, we...
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Báo cáo khoa học: Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, expressed in human embryonic kidney 293T cells ppt
Ngày tải lên :
16/03/2014, 14:20
... proteins into the ER [18] The strong inhibition of the processing of pro-cathepsin E into the mature enzyme by brefeldin A indicates that the processing and maturation of this protein occur in ... propeptides, and N-glycosylation of cathepsin E in its processing, maturation, and trafficking must be of particular importance In this study, to understand the molecular basis of the processing and intracellular ... pro-cathepsin E in the culture Recombinant cathepsin E and its mutants medium (Fig 2C) Given that bafilomycin A1 effectively inhibits acidification of intracellular acidic organelles including endosomes,...
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Báo cáo khoa học: "Characterizing and Recognizing Spoken Corrections in Human-Computer Dialogue" pot
Ngày tải lên :
17/03/2014, 07:20
... In Eurospeech '97 M Swerts and M Ostendorf 1995 Discourse prosody in human- machine interactions In Proceedings of the ECSA Tutorial and Research Workshop on Spoken Dialog Systems - Theories and ... found, and this difference can easily be explained by the combination of two simple trends First, there was a decrease in the number of final rising contours, and second, t h e r e were increases in ... accent and contour had shown some utility in identifying certain discourse relations [ (Pierrehumbert and Hirschberg, 1990), (Hirschberg and Litman, 1993) Although changes in pitch maxima and minima...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
Ngày tải lên :
17/03/2014, 10:20
... data points in the F2 dimension, 16–32 transients and 720–1024 complex increments in the F1 dimension Raw data were multiplied in both dimensions by a pure cosine-squared bell window function and ... studies carried out in 40% TFE in an H2O mixture [38] According to studies of CRH binding to single bilayer egg phosphatidylcholine vesicles, the development of the intramolecular interaction with ... E.B., Insel, T.R., Perrin, M.H., Rivier, J., Vale, W.W & Kuhar, M.J (1985) Differential regulation of corticotropinreleasing factor receptors in anterior and intermediate lobes of pituitary and in...
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Báo cáo khoa học: Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells pot
Ngày tải lên :
23/03/2014, 13:20
... HO-1 in human RPE cell lines In contrast to interferon-c, hypoxia induced the expression levels of HO-1 mRNA in D407 cells and exerted no or only marginal effects in ARPE-19 cells (Fig 2) In D407 ... cultured human RPE cells [35] In this case, interferon-c has been shown to inhibit proliferation of parasites by inducing the expression of indoleamine 2,3-dioxygenase, a heme-containing enzyme ... the HO-1 gene in mice [47] and in cultured human lung cancer cells [27] The expression levels of HO-1 and Bach1 mRNAs are inversely regulated by interferon-c in both RPE cell lines In contrast,...
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Báo cáo khoa học: DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine pptx
Ngày tải lên :
30/03/2014, 02:20
... in cells Harmine is a potent inhibitor of DYRK1A in cells The b-carboline alkaloid harmine has recently been reported as a specific DYRK inhibitor in vitro by Bain et al [19] Harmine inhibits purified ... including malarial infection and Parkinson’s disease [42] Harmine and related b-carbolines have cytotoxic activity towards human tumour cell lines in culture [43], suggesting a possible use in ... suggesting a role in neurogenesis like its Drosophila orthologue, minibrain (mnb) [4] Studies in both mouse and Drosophila have found an important role for DYRK1A ⁄ minibrain kinase in determining...
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Báo cáo khoa học: "INTEGRATING MULTIPLE KNOWLEDGE SOURCES FOR DETECTION AND CORRECTION OF REPAIRS IN HUMAN-COMPUTER DIALOG*" potx
Ngày tải lên :
31/03/2014, 06:20
... can be helpful in detecting repairs is acoustics In this section we describe firsthow prosodic information can help in distinguishing repairs from false positives for patterns involving matched ... Furthermore, pattern matching alone contains insufficient information for reliably correcting these sentences Acoustic features reported in the following analyses were obtained by listening to the sound ... significant And, as system developers move toward more closely modeling human- human interaction, the percentage is likely to rise The basic aspects of the notation include marking the interruption point,...
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Báo cáo hóa học: " Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects" potx
Ngày tải lên :
18/06/2014, 16:20
... where recruited into the study after understanding and signing informed consent Exclusion criteria included: systemic immune-compromised state, ongoing infection or disease conditions, and significant ... subsequent studies have expanded this finding to situations of inflammation [44], and peripheral tissue injury [45-47] Hematopoietic stem cells are being increasingly recognized as having diverse non-hematopoietic ... functions including production of angiogenic cytokines [48], and acting as an “innate” immune cell capable of rapidly differentiating into dendritic cells for protection of the host against infections...
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báo cáo hóa học:" Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes Malinee Pongsavee" docx
Ngày tải lên :
20/06/2014, 00:20
... cells in tissue culture provides a potential mechanism for increasing invasive mammary carcinoma [5] and induced colonic neoplasia in animal models [6] Borax is used as a food additive in some ... (Invitrogen, Carlsbad, CA, USA) and penicillin-streptomycin antibiotic Phytohemagglutinin was added in RPMI medium as the mitogen and incubated for 72 hours After 72 hours incubation, a total of × 105 ... nephrotoxicity and neurotoxicity in human but the borax toxicity about human genetic materials and humoral immune cell still need to be investigated for food additive carcinogenesis The defect in genetic...
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Báo cáo hóa học: " Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector" doc
Ngày tải lên :
20/06/2014, 01:20
... Low) in HCV polyprotein expressing cells and in staurosporine treated cells, in contrast with cells infected with the VT7-HCV7.9 in the absence of IPTG or in uninfected cells These results indicate ... shown in Fig 5A, the cytochrome c remained confined to the mitochondria in both uninfected cells and VT7-HCV7.9infected cells in the absence of IPTG However, in cells infected with VT7HCV7.9 in ... labelling on ultrathin sections Due to the fixation and embedding procedures used in immunostaining, the cell structures are less visible than by embedding in an epoxy resin While in cells infected with...
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Báo cáo lâm nghiệp: " Zygotic embryogenesis and empty seed formation in European larch (Larix decidua Mill.)" pptx
Ngày tải lên :
08/08/2014, 00:21
... inbreeding and genetic variances in a natural population of tamarack (Larix laricina (Du Roi) K Koch) in Eastern Canada, Silvae Genet 31 (1982) 21–26 [27] Paule L., Gömöry D., Mating system in ... studied by nonlinear correlation Pollination efficiency was expressed by the mean number of pollen grains per pollinated ovule, quantified at the end of the pollination period and published in our earlier ... of pollinated, but unfertilized, ovules is almost constant [34] Therefore, the existence of a pre-zygotic incompatibility between ovules and self-pollinating pollen grains is not assumed and, most...
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Báo cáo khoa học: "Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications" doc
Ngày tải lên :
09/08/2014, 07:21
... http://www.wjso.com/content/6/1/59 Intense immunostaining for CAR in tumor cells in representative endometrial adenocarcinoma cases (original magnification Figure ×200) Intense immunostaining for CAR in tumor cells in representative ... (high vs low level of CAR expression) and staining intensity (mild vs moderate and intense CAR staining intensity) in patients with endometrial adenocarcinoma did not reveal statistically significant ... adenovirus, but also to inhibit cell growth in bladder cancer and malignant glioma cells [13,16,18,33] The latter is not in line with the current findings and could be ascribed to the individual characteristics...
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Báo cáo y học: "The relationship between inflammation and new bone formation in patients with ankylosing spondylitis" docx
Ngày tải lên :
09/08/2014, 13:21
... [18,19] given that spinal inflammation was shown to be associated with the presence of TNF-α mRNA [18] and protein [20] in affected joint and bone structures Accordingly, inhibition of TNF-α was ... D van der: Combining information obtained from magnetic resonance imaging and conventional radiographs to detect sacroiliitis in patients with recent onset inflammatory back pain Ann Rheum Dis ... and the lumbar spine in the lateral view at BL and 2yFU were taken Because of the known technical problems in the assessment of the thoracic spine in standard x-rays [4], this part of the spine...
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Báo cáo y học: "Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment" ppt
Ngày tải lên :
09/08/2014, 13:22
... proteins and is involved in disruptive events in the cartilage and bone of inflamed joints [15] Recent publications suggest that it is closely related to inflammation and high disease activity in ... (d_VEGF) and d_CRP, (c) bone-specific alkaline phosphatase (d_BALP) and d_CRP, and (d) protein (d_CRP), (b) vasoenCorrelation of differences in serum levels at baseline and year of (a) metalloproteinase-3 ... in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab: results of a multicenter, randomized, double-blind, placebo-controlled magnetic resonance imaging...
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Báo cáo y học: "Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocyte" ppsx
Ngày tải lên :
09/08/2014, 14:20
... attenuates the inflammatory stimuli-induced activation and DNA binding activity of NF-κB in human chondrocytes In order to gain further insight into the mechanism, we used an in vitro kinase activity ... performing kinase activity assays with recombinant human IKKβ kinase It includes active IKKβ kinase (supplied as GST fusion protein), a biotinylated peptide substrate, and a phospho-serine antibody ... ligands including S100 protein, high-mobility group box chromosomal protein and AGEs (complex and specific AGEs) in OA chondrocytes and synoviocytes results in increased production of various inflammatory...
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Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines ppt
Ngày tải lên :
10/08/2014, 05:21
... 1Bb) Finally, we examined two lineage-specific markers expressed in EBs, the neural (Nestin) and cardiac specific genes (Nkx 2.5 and cTn1) and found P10 had higher expression of Nestin and cTn-1 ... transcriptase (Invitrogen, Carlsbad, CA, http://www.invitrogen.com), Random primer (Invitrogen), 10 mM dNTPs (Invitrogen), 5× First Strand synthesis buffer, 0.1 M DTT, and RNaseOUT ribonuclease RNase inhibitor ... telomere ends [11] In mammals, DNA methylation of cytosines in cytosine guanine dinucleotide (CpG) islands, known to mediate epigenetic gene silencing [12,13], plays pivotal roles in embryonic development...
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