hematopoietic stem cell vascular niche

... hematopoietic stem cells. Science 241, 58–62. 10. Uchida, N. and Weissman, I. L. (1992) Searching for hematopoietic stem cells: evidence that Thy-1.11o Lin- Sca-l+ cells are the only stem cells in ... their propensity to mobilize stem and progenitor cells in response to cytokine administration (23). Recent studies have also demonstrated that stem cell pool size and stem cell cycling characteristics ... (12,28). Therefore, a dose-response experiment Cell Cycle Analysis of Stem Cells 93 93 From: Methods in Molecular Medicine, vol. 63: Hematopoietic Stem Cell Protocols Edited by: C. A. Klug and C....

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... tế bào gốc trưởng thành ở giai đoạn biệt hóa thấp. c/ Tế bào gốc trưởng thành (Adult stem cells/Somatic stem cells): Còn gọi là tế bào gốc thân. Là các tế bào chưa biệt hóa được tìm thấy với một ... Các tế bào gốc phôi lấy từ khối tế bào bên trong (inner cell mass) là những tế bào gốc vạn năng. c/ Tế bào gốc đa năng (multipotent stem cells): Là những tế bào có khả năng biệt hóa thành nhiều ... biệt hóa khác nhau của tế bào gốc tạo máu: - Các tế bào gốc tạo máu dài hạn (long-term hematopoietic stem cells): đây là các tế bào gốc tạo máu ít biệt hóa hơn, nói cách khác là “non” hơn, có...

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... disease. Keywords allogeneic hematopoietic stem cell transplantation, chronic graft-versus-host disease, children, incidence, risk factors Introduction Hematopoietic stem cell transplantation (HSCT) ... common after peripheral blood stem cell transplantation than BMT because it is generally accepted that peripheral blood stem cells con- tain greater numbers of infused T-cells (Bishop, 2009; Schmitz ... T cells in graft vs host disease. Journal of Immunol- ogy, 152, 1609-1617. Huang, X., Liu, D., Liu, K., Xu, L., Chen, H., Han, W., . . . Zhang, X. (2009). Haploidentical hematopoietic stem cell...

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... in mouse embryonic stem cells. Stem Cells 27, 3001- 3011. New Advances in Stem Cell Transplantation 14 Fig. 3. Methods for production of induced pluripotent stem cells (iPSCs) by excisable ... Mesenchymal Stem Cells 183 Pearly Yong, Ling Qian, YingYing Chung and Winston Shim Part 2 Clinical Aspects of Stem Cell Transplantation 197 Chapter 11 Sources of Hematopoietic Stem Cells 199 ... Chapter 12 Cryopreservation of Hematopoietic and Non -Hematopoietic Stem Cells – A Review for the Clinician 231 David Berz and Gerald Colvin Chapter 13 Hematopoietic Stem Cell Transplantation for...

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... this report are common to other areas of human stem cell research, such as research with adult stem cells, fetal stem cells, or embryonic germ cells derived from fetal tissue. Institutions and investigators ... reserved. Guidelines for Human Embryonic Stem Cell Research http://www.nap.edu/catalog/11278.html 16 Guidelines for Human Embryonic Stem Cell Research team derived stem cells from primordial gonadal tissue ... (blood-forming) adult stem cells from bone marrow or from umbilical cord blood give rise to all the cells of the blood. Skin cell transplants similarly rely on the transfer of skin stem cells. In both...

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... disruption of Ptb in ES cells. Ptb ) ⁄ flox ES cells were generated by expression of Cre in Ptb ) ⁄ flox-hyg ES cells. Ptb ) ⁄ ) ES cells were generated by infection of Ptb ) ⁄ flox ES cells with a retroviral ... and Systems Biology, Institute of Medical Science, University of Tokyo, Japan Introduction Mouse embryonic stem (ES) cells are established from the inner cell mass (ICM) of blastocysts. ES cells ... the process by which a stem cell divides to generate one or two daughter stem cells with developmental potentials that are indistinguish- able from that of the mother cell. This process is cen- tral...

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... effector T cells upon recognition of the beta -cell- specific peptide bound to MHC class I molecules in the presence of beta -cell- specific CD4 + T helper cells. The cytotoxic CD8 + T cells then ... affect beta -cell damage by releasing perforin and granzyme, and by Fas-mediated apoptosis. In this way, macrophages, CD4+ T cells, and CD8+ T cells synergistically destroy beta-cells, resulting ... that lead to beta -cell- specific T cell activation (The term cross-presentation denotes the ability of certain antigen-presenting cells to take up, process and present extracellular antigens...

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