hematopoietic stem cell transplantation reflections on yesterday and thoughts for tomorrow

Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx

Ngày tải lên : 09/08/2014, 01:23

... References 10 11 12 13 14 Marmont AM, van Lint MT, Gualandi F, Bacigalupo A: Autologous marrow stem cell transplantation for severe systemic lupus erythematosus of long duration Lupus 1997, 6:545-548 ... Autoimmune Disease and Lymphoma Working Parties of the European Group for Blood and Marrow Transplantation, the European League Against Rheumatism and the International Stem Cell Project for Autoimmune ... opportunistic infections Patients should be screened for cardiac symptoms, for avascular necrosis and for occult infection prior to registration In addition, aggressive antiviral, fungal and bacterial...

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Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx

Ngày tải lên : 10/08/2014, 21:23

... Hematology & Oncology 2011, 4:9 http://www.jhoonline.org/content/4/1/9 Page of Figure Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation Chronological dates ... QFL: provided the conception and design of the paper, revised it critically for important intellectual content, and final approval of the version to be submitted Authors’ information QFL, MD, Ph.D, ... mofetil (0.5 g twice a day on days to +28) for GVHD prophylaxis; Caspofungin for prophylaxis of fungal infections] Tropisetron was used during the chemotherapy and conditioning (E) period of acute...

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Báo cáo y học: "Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation" pot

Ngày tải lên : 10/08/2014, 21:23

... P: Patterns of T -cell reconstitution by assessment of T -cell receptor excision circle and T -cell receptor clonal repertoire after allogeneic hematopoietic stem cell transplantation in leukemia ... probe, and PCR buffer with 4.5 mM MgCl2 After an initial denaturation at 95°C for min, 45 cycles consisting of 95°C for 30 s and 67°C for were performed The amplification was performed on MJ Research ... precursor cells Because thymic function is necessary for de novo generation of T cells after transplantation, quantification of T -cell receptor excision DNA circles (TRECs) in peripheral blood T cells...

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Báo cáo y học: "Marked increase of procalcitonin after the administration of anti-thymocyte globulin in patients before hematopoietic stem cell transplantation does not indicate sepsis: a prospective study" pptx

Ngày tải lên : 13/08/2014, 16:20

... infection in patients receiving ATG prior to hematopoietic stem cell transplantation We also assessed renal and liver functions and their relationship to PCT and CRP changes Materials and methods ... transferase infection in this population Patients undergoing conditioning before hematopoietic stem cell transplantation represent a distinct population with significantly altered immune response This ... observational non-randomized study, we prospectively evaluated a cohort of 26 adult patients indicated for an ATG conditioning regimen prior to hematopoietic stem cell transplantation The patients...

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báo cáo hóa học: " Function, Adjustment, Quality of Life and Symptoms (FAQS) in Allogeneic Hematopoietic Stem Cell " potx

Ngày tải lên : 20/06/2014, 15:20

... status of hematopoietic cell transplantation Annu Rev Med 2003, 54:491-512 Horowitz MM: Uses and growth of hematopoietic cell transplantation In Thomas’ hematopoietic cell transplantation edition Edited ... screening and preventive practices for long-term survivors after hematopoietic cell transplantation: joint recommendations of the European Group for Blood and Marrow Transplantation, the Center for ... Health and functional status of long-term survivors of bone marrow transplantation EBMT Working Party on Late Effects and EULEP Study Group on Late Effects European Group for Blood and Marrow Transplantation...

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Báo cáo y học: "Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms" pps

Ngày tải lên : 10/08/2014, 21:23

... analyses were performed on genomic DNA from mononuclear cells of the patient pre-transplant, of the AML blast cell sample obtained after transplantation, and of the donor bone marrow cells The 11 ... response; peripheral blood infiltration by blast cells rose to 80% after 14 days Palliative support began and the patient died after 17 months of stem cell infusion Discussions and Conclusions ... repair mechanism Patient cells (pretransplantation) AML cells (posttransplantation) Donor cells XPA A23G NER Homozygous for optimal DRC Homozygous for optimal DRC Homozygous for optimal DRC XPD Lys751Gln...

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báo cáo khoa học: "Multiple Myeloma Involving Skin and Pulmonary Parenchyma after Autologous Stem Cell Transplantation" potx

Ngày tải lên : 10/08/2014, 22:20

... complication of relapsed disease after autologous stem cell transplantation The presence of circulating plasma cells and hyperammonemia are both known to be indicators of advanced disease Plasma cell ... interests Authors' contributions All authors were involved in the provision of clinical care of the patient and the collection of data and the review of the manuscript RW performed immunohistochemical ... proxy for the patient's informed consent for the publication of the manuscript and accompanying images, in light of the fact that the patient had expired A copy of the written documentation of...

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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" doc

Ngày tải lên : 12/08/2014, 04:21

... complications of infections after autologous stem cell transplantation or intensive chemotherapeutic treatment, HHV-6 detection should be included into the diagnostic work-up for these patients and longitudinal ... asymptomatic HHV6 reactivation is frequently reported in patients after allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, ... interests Authors' contributions GJ and BM were responsible for the patients care, PS interpreted the chest-CT and the MRI and added the figures, BM wrote the paper and all authors read and approved...

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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" ppsx

Ngày tải lên : 12/08/2014, 04:22

... complications of infections after autologous stem cell transplantation or intensive chemotherapeutic treatment, HHV-6 detection should be included into the diagnostic work-up for these patients and longitudinal ... asymptomatic HHV6 reactivation is frequently reported in patients after allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, ... interests Authors' contributions GJ and BM were responsible for the patients care, PS interpreted the chest-CT and the MRI and added the figures, BM wrote the paper and all authors read and approved...

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Myocardial protection and therapeutic angiogenesis using peptide and embryonic stem cell transplantation

Ngày tải lên : 14/09/2015, 09:26

... revascularization Cell source PRE-CLINICAL Bone marrow derived Animal model Rat Ligation model Bone marrow derived mononuclear cells Rat ligation model Bone marrow derived mononuclear cells Porcine ligation ... angiogenesis and vasculogenesis: Cellular approach Adult mesenchymal stem cells Smooth muscle cells Hematopoietic stem cells and progenitor cells Endothelial progenitor and endothelial cells Bone marrow-derived ... various cell sources for induction of neovascularization in infarcted myocardium is listed in Table Adult mesenchymal stem cells Mesenchymal stem cells constitute one of the stem cell populations...

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Tài liệu Review of Chronic Graft- Versus-Host Disease in Children After Allogeneic Stem Cell Transplantation: Nursing Perspective pptx

Ngày tải lên : 12/02/2014, 19:20

... odds for chronic GVHD Peripheral blood stem cell transplantation results in an increased risk for chronic GVHD compared with bone marrow transplantation Age at transplantation and a female donor ... marrow transplantation Chronic GVHD is more common after peripheral blood stem cell transplantation than bone marrow transplantation Acute GVHD, malignant disease, recipient age (>10 years), and ... Chronic GVHD (%) Abbreviations: GVHD, graft-versus-host disease; PBSCT, peripheral blood stem cell transplantation; BMT, bone marrow transplantation; UBMT, unrelated bone marrow transplantation; ...

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Tài liệu INNOVATIONS IN STEM CELL TRANSPLANTATION doc

Ngày tải lên : 18/02/2014, 04:20

... fibroblasts and endothelium cells [154] They are ligands for NKG2D [155], a receptor present on NK cells and some T cells, and because of this they can co-stimulate NK cells and T cells and can therefore ... kine gene expression in peripheral blood mononuclear cells and alloreactivity in hematopoietic cell transplantation with nonmyeloblative conditioning Biol Blood Marrow Transplantation 2006;12:48-60 ... must be on Good Manufacturing Proce‐ dures (GMP) and careful monitoring of the long-term effects of transplanted stem cells in the host In conclusion, Cell Transplantation is bridging cell transplantation...

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Tài liệu New Advances in Stem Cell Transplantation Edited by Taner Demirer ppt

Ngày tải lên : 20/02/2014, 08:20

... Cryopreservation of Hematopoietic and Non -Hematopoietic Stem Cells – A Review for the Clinician 231 David Berz and Gerald Colvin Chapter 13 Hematopoietic Stem Cell Transplantation for Adult Acute ... must be on Good Manufacturing Procedures (GMP) and careful monitoring of the long-term effects of transplanted stem cells in the host In conclusion, Cell Transplantation is bridging cell transplantation ... Methods for Stem Cell Transplantation Johan Lundberg and Staffan Holmin 159 Dynamic Relationships of Collagen Extracellular Matrices on Cardiac Differentiation of Human Mesenchymal Stem Cells 183...

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Tài liệu Trade Reforms and Crisis in India’s Plantation Agriculture: Reflections on Tea and Rubber Plantation Sectors pdf

Ngày tải lên : 21/02/2014, 04:20

... of production, employment and trade and changing policy environments Examine differential responses from the plantation sector and their implications on sustainable production systems and livelihoods ... the plantation system, per se, which has lost its relevance as a production system in the context of global economic integration and new trade reform measures II Objectives Understand the macro ... regional contexts: coffee, rubber & spices concentration in the South; tea concentrated in the North, NE and Southern regions Turmoil in the plantation sector means collapse of the regional economies…...

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hematopoietic stem cell protocols

Ngày tải lên : 11/04/2014, 09:45

... donor-derived cells: once at 1–2 mo posttransplantation as a preliminary screening for engraftment, and once at 4–6 mo posttransplantation for true HSC-derived contribution (19) To assay for multilineage ... injected cells is able to home to bone marrow and detectably reconstitute (13) Most clones give transient multilineage reconstitution, and only 15% of clones give long-term reconstitution Fifty-three ... pairs (bp) for LacZ and 245 bp for myogenin The conditions for the YMT-2 male marker-myogenin PCR are: 92oC for min, followed by 30 cycles at 92oC for min, 60oC for min, and 72oC for min, and a final...

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ADVANCES IN HEMATOPOIETIC STEM CELL RESEARCH pot

Ngày tải lên : 27/06/2014, 13:20

... into four sections: 1) Hematopoietic stem cell properties, 2) Regulation of hematopoietic stem cells, 3) Hematopoietic stem cells in aging and disease, and 4) Hematopoietic stem cell therapy The ... differentiation at Cell Stem Cell Cell Stem Cell Jun 5;2(6):510 2 Regulation of Hematopoietic Stem Cell Fate: Self-Renewal, Quiescence and Survival 1Division Yasushi Kubota1,2 and Shinya Kimura1 ... required for homing of HSCs to bone marrow Taken together, Tie receptors seem one group of the likely candidates for localizing stem cells to the stem cell niche Mineral content of bone contributes...

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Báo cáo y học: "Stem cell transplantation for rheumatic autoimmune diseases" potx

Ngày tải lên : 09/08/2014, 10:23

... action of hematopoietic stem cell transplantation in autoimmune disease Autologous hematopoietic stem cell transplantation In autologous HSCT, conditioning with high-dose cyclophosphamide, ATG, and/ or ... increases in T -cell receptor excision circles and CD31+ T cells and normalisation of new T -cell receptor repertoires [53,54] Allogeneic hematopoietic stem cell transplantation The interaction of two ... depend on the conditioning regimen and whether or not TBI is performed [22] With adaptation of eligibility criteria (for example, exclusion of patients with severe pulmonary hypertension) and modificaPage...

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Báo cáo y học: "Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cell" ppsx

Ngày tải lên : 10/08/2014, 10:20

... factors or direct cell contact with host cells; while intracranial transplantation only rescued a smaller portion of PCs and failed to improve motor function Together, transplantation of hMSCs can ... [25,26] hMSCs of passage 810 were used for transplantation Before transplantation, hMSCs were trypsinized with trypsin/EDTA 0.25%, counted for cell number and suspended in 80 μL PBS Animal Model ... stain of whole brain sections and identification of engrafted human cells OKL conceived of the study and participated in its design and coordination All authors read and approved the final manuscript...

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