... Page 1Introduction to StemCell and BoneMarrow TransplantationThe pluripotent stem cells from which all committed blood cells arise (Figure I.1) are located in the bone marrow space, the peripheral ... harvesting116 Bone marrow processing116Mobilization and collection of peripheral blood stem cells118Umbilical cord blood collection120Infusion of marrow -stem cells121Chapter 5Management of Stem Cell/ Bone ... Blood Stem Cell, and Umbilical Cord BloodProcurement and InfusionDeborah Branney Davison113Allogeneic bonemarrow harvest113Autologous bonemarrow harvest115Complications of bone marrow...
... patientsundergoing bonemarrow transplantation. Transplantation. 1991;5:630–635.Or R, Mehta J. Nagler A, Cvacium I. Neutropenia enterocolitis associated with autologous bone marrow transplantation. BoneMarrow ... in bonemarrow transplant patients. BoneMarrow Transplant. 1990;5:387–393.HemorrhageAtkinson K, Biggs JC, Golovsky D. Bladder irrigation does not prevent haemorrhagic cystitis in bone marrow ... undergoingautologous bonemarrow transplantation. BoneMarrow Transplant. 1991;7:421–425.Ireland RM, Atkinson K, Conconnon AJ. Serum erythropoietin changes in autologous andallogeneic bonemarrow transplant...
... 113Chapter 4— Bone Marrow, Peripheral Blood Stem Cell, and Umbilical Cord BloodProcurement and InfusionThe term harvest refers to the procurement of bone marrow, peripheral blood stem cells (PBSCs),or ... continue in an effort to improve stemcell expansion techniquesto allow transplantation in an older child or adult.VII. Infusion of MarrowStem CellsA. Marrow or stemcell infusion is planned to ... placental blood hematopoietic stem cells: collection, cryopreservation, and storage. J Hematother. 1992;1:167–173.9. Patterson K. Bonemarrow processing. In: Treleaven J, Wiernik P, eds. Bone Marrow Transplantation....
... numbers of stem cells, ex vivo manipulation of marrow (purging), andcryopreservation.33. Risk factorsa) Recipient of HLA-incompatible marrow graftb) Recipient of matched unrelated donor marrow ... sibling donor recipient is thought toresult from marrow rejection by host T cells not eliminated during conditioning. 9d) T -cell depletion of donor marrow to prevent GVHD also contributes to graftrejection.e) ... pretransplantconditioningg) T -cell depletion of marrow graft orh) Ex vivo marrow manipulation (purging/cryopreservation)4. Clinical featuresa) A complete absence of hematopoietic activity (rise...
... hematopoieticstem cells. Science 241, 58–62.10. Uchida, N. and Weissman, I. L. (1992) Searching for hematopoieticstem cells:evidence that Thy-1.11o Lin- Sca-l+ cells are the only stem cells in ... iodide Negative to low Dead -cell exclusionAbbreviations: FBM, fetal bone marrow; MPB, mobilized peripheral blood; ABM, adult bone marrow; HSC, hematopoieticstem cells; FITC, fluorescein; PE, ... removed, so a Ficoll separation will not en-rich the stem cells relative to the other nucleated cells.Whole bone marrow: Whole aspirated bonemarrow is essentially always con-taminated with variable...
... functioning of adult survivors of allogeneic bone marrow transplantation. BoneMarrow Transplant 1989, 4(5):505-509.34. Molassiotis A: Quality of life following bonemarrow transplant. NursTimes 1995, ... unrelated donor bonemarrow transplantation. Bone Marrow Transplant 1999, 24(2):191-195.50. Wingard JR, Curbow B, Baker F, Zabora J, Piantadosi S: Sexual satisfactionin survivors of bonemarrow transplantation. ... current status of hematopoieticcell transplantation.Annu Rev Med 2003, 54:491-512.6. Horowitz MM: Uses and growth of hematopoieticcell transplantation. InThomas’ hematopoieticcell transplantation...
... without stemcell support.Competing interestsNone declared.References1. Marmont AM, van Lint MT, Gualandi F, Bacigalupo A: Autologous marrow stemcell transplantation for severe systemic lupuserythematosus ... systemic lupus erythe-matosus with high-dose chemotherapy and haemopoietic stem- cell transplantation: a phase I study. Lancet 2000, 356:701-707.4. Traynor A, Burt RK: Haematopoietic stemcell ... hematopoieticstem cells are infused in order toshorten the past transplant neutropenic interval by4–6 days compared with the same dose of cyclophos-phamide without hematopoieticstemcell support,...
... http://www.medsci.org 75 searchers have transplanted the bonemarrowstem cells into the necrotic femoral heads, and results show bone marrowstem cells can remove vascular lesions and promote angiogenesis ... head necrosis; bonemarrow mesenchymal stem cell; migration; safety Introduction Recently, stemcell transplantation has been a focus in the treatment of some diseases. Stem cells have the ... Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types. In the field of cell transplantation, MSCs have many advantages over other cell types...
... support (Figure 1). A stem cells injectate includ-ing a mixed population of endothelial progenitor cells(CD133+), haematopoiet ic stem cells (CD34+), andmesenchymal stem cells (CD105+) was ... injecting directly autologous bone marrow mononuclear stem cells (BMSCs) into thehibernating myocardium. Our aim is to enhance nativemyocardial recovery with the use of stem cells while theheart is ... role of stem cell therapy in HF is that each cell- based study uses aunique protocol regarding the optimal cell type, thenumber of cells to be delivered, and the most suitableroute for cell delivery....
... prepared from rat bonemarrow asdescribed by Friedenstein et al [9]. In brief, we eutha-nized Sprague Dawley (SD) rats weighted 80-100 g andharvested bone marrow. Bonemarrow cells were intro-duced ... befurther improved by transplantation with bone marrow- derived mesenchymal stem cells (MSCs) modified bySurvivin (SVV).Methods: MSCs derived from bonemarrow of male Sprague-Dawley rats were infected ... capacityof cellsCells were scattered in a number of colony distributions3 days after planted. At day 8 ~ 9, the bottle was cov-ered with long-spindle cells. Passaged cells (mostly spin-dle cells)...