hematopoietic stem cell differentiation pdf
hematopoietic stem cell protocols
... hematopoietic stem cells. Science 241, 58–62. 10. Uchida, N. and Weissman, I. L. (1992) Searching for hematopoietic stem cells: evidence that Thy-1.11o Lin- Sca-l+ cells are the only stem cells in ... their propensity to mobilize stem and progenitor cells in response to cytokine administration (23). Recent studies have also demonstrated that stem cell pool size and stem cell cycling characteristics ... (12,28). Therefore, a dose-response experiment Cell Cycle Analysis of Stem Cells 93 93 From: Methods in Molecular Medicine, vol. 63: Hematopoietic Stem Cell Protocols Edited by: C. A. Klug and C....
Ngày tải lên: 11/04/2014, 09:45
Báo cáo sinh học: " Risk factors in the development of stem cell therapy" pdf
... accom- panied by cell sorting to mini mise the number of pluri/ multipotent stem cells in the cell preparation [86], or to separate tumourigenic stem cells from non-tumouri- genic stem cells (by e.g. cell ... cultured cells, includ- ing stem cells. These risk factors are not unique to stem cells and apply to all cell based medicinal products. Donor history is of particular importance for stem cell lines ... Approach for the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell 2008, 2:525-528. 81. Uccelli A, Moretta L, Pistoia V: Mesenchymal stem cells in health and disease. Nature Reviews Immunology...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " Function, Adjustment, Quality of Life and Symptoms (FAQS) in Allogeneic Hematopoietic Stem Cell " potx
... EA, Cella DF, Beaumont JL, Brady MJ, Horowitz MM, Sobocinski KA, Rizzo JD, Wingard JR: Long-term health- related quality of life, growth, and spiritual well-being after hematopoietic stem- cell ... [http://www. marrow.org/PATIENT/Survivorship_Ed/assets/pdfs/ Suvivorship_Stages_of_Recovery .pdf] , Accessed April 1, 2011. 5. Appelbaum FR: The current status of hematopoietic cell transplantation. Annu Rev Med 2003, ... transplantation. Annu Rev Med 2003, 54:491-512. 6. Horowitz MM: Uses and growth of hematopoietic cell transplantation. In Thomas’ hematopoietic cell transplantation 4 edition. Edited by: Appelbaum F, Thomas ED....
Ngày tải lên: 20/06/2014, 15:20
Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx
... without stem cell support. Competing interests None declared. References 1. Marmont AM, van Lint MT, Gualandi F, Bacigalupo A: Autologous marrow stem cell transplantation for severe systemic lupus erythematosus ... systemic lupus erythe- matosus with high-dose chemotherapy and haemopoietic stem- cell transplantation: a phase I study. Lancet 2000, 356: 701-707. 4. Traynor A, Burt RK: Haematopoietic stem cell ... hematopoietic stem cells are infused in order to shorten the past transplant neutropenic interval by 4–6 days compared with the same dose of cyclophos- phamide without hematopoietic stem cell support,...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx
Ngày tải lên: 10/08/2014, 21:23
Autoimmune Diseases – Contributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other Therapies pdf
... effector T cells upon recognition of the beta -cell- specific peptide bound to MHC class I molecules in the presence of beta -cell- specific CD4 + T helper cells. The cytotoxic CD8 + T cells then ... affect beta -cell damage by releasing perforin and granzyme, and by Fas-mediated apoptosis. In this way, macrophages, CD4+ T cells, and CD8+ T cells synergistically destroy beta-cells, resulting ... that lead to beta -cell- specific T cell activation (The term cross-presentation denotes the ability of certain antigen-presenting cells to take up, process and present extracellular antigens...
Ngày tải lên: 16/03/2014, 21:20
EMBRYONIC STEM CELLS – DIFFERENTIATION AND PLURIPOTENT ALTERNATIVES pdf
... Alternatives Other Cell Sources Chapters 22-25 describe alternative sources of pluripotent stem cells. These include very small embryonic/epiblast like stem cells, multipotent dental stem cells, pluripotent ... cells, multipotent dental stem cells, pluripotent stem cells from testis and amniotic fluid stem cells. In the book Embryonic Stem Cells - Differentiation and Pluripotent Alternatives, the story ... interesting in two biological contexts with respect to stem cell differentiation: maintenance of pluripotent stem cells and tumorigenesis of cancer stem cells. In the first context, inhibition of PTEN,...
Ngày tải lên: 28/06/2014, 04:20
Chapter 066. Stem Cell Biology (Part 2) pdf
... cultured stem cells. For abbreviations of stem cells, see Table 66-1. Note that stem cells are often abbreviated with or without "cells," e.g., ES cells or ESCs for embryonic stem cells. ... germ cells. Multipotent cells (e.g., HS cells) can form multiple cell lineages but cannot form all of the body's cell lineages. Oligopotent cells (e.g., NS cells) can form more than one cell ... stem cells. Mouse ES cells can form teratomas when injected into immunosuppressed animals. Potency and Differentiation of Stem Cells Potency and source developmental stage of cultured stem...
Ngày tải lên: 07/07/2014, 01:20
Chapter 066. Stem Cell Biology (Part 3) pdf
... Differentiation of Stem Cells Pluripotent stem cells (e.g., ES cells) can differentiate into multiple cell types, but in culture they normally differentiate into heterogeneous cell populations ... reprogramming of somatic cells by transfecting specific genes or by exposing the cells to ES cell extracts is the subject of current research. Stem Cell Plasticity or Transdifferentiation The ... therapeutic uses, it is desirable to direct stem cells into specific cell types (e.g., insulin-secreting beta cells). This is an active area of stem cell research, and protocols are being developed...
Ngày tải lên: 07/07/2014, 01:20
Chapter 068. Hematopoietic Stem Cells (Part 3) pdf
... proliferation. Hematopoietic stem cells have governing mechanisms that are distinct from the cells they generate. Hematopoietic Stem Cell Differentiation Hematopoietic stem cells sit at ... Chapter 068. Hematopoietic Stem Cells (Part 3) Excess Capacity of Hematopoietic Stem Cells In the absence of disease, one never runs out of hematopoietic stem cells. Indeed, serial ... location of stem cells by indirect means, altering molecules such as CXCL12 that tether stem cells to their niche. Molecules shown to be important for altering the proliferation of stem cells, such...
Ngày tải lên: 07/07/2014, 01:20
Chapter 068. Hematopoietic Stem Cells (Part 4) pdf
... blood stem cells have Chapter 068. Hematopoietic Stem Cells (Part 4) Hierarchy of hematopoietic differentiation. Stem cells are multipotent cells that are the source of all descendant cells ... use fewer stem cells or expand limited numbers of stem cells ex vivo, it might be possible to reduce the morbidity and expense of stem cell harvests and enable use of other stem cell sources. ... important function of stem cells because it is critical in regulating the number of stem cells. Stem cell number is a key limiting parameter for both autologous and allogeneic stem cell transplantation....
Ngày tải lên: 07/07/2014, 01:20
Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines ppt
... co-cultured CD34+ hematopoietic stem cells with 3A6 cells, we noted the formation of cobblestone areas from hematopoietic cells that transmigrated beneath the layer of 3A6 cells (Figure 3C). Previously, ... mesenchymal stem cell in vitro. BMC cell biology 2006, 7:14. 5. Hung SC, Chen NJ, Hsieh SL, Li H, Ma HL, Lo WH: Isolation and characterization of size-sieved stem cells from human bone marrow. Stem cells ... associated with differentia- tion of neural stem cells, hematopoietic stem cells and MSCs. However, an increase in Oct4 expression in ESCs causes differentiation into primitive endoderm [29], mesoderm...
Ngày tải lên: 10/08/2014, 05:21