hematopoietic cell transplantation in myelodysplastic syndromes

... cells survival in the host striatum, we performed HE staining and cytokeratin immunostain- ing. HE staining showed that transplants were accurately placed into the striatum (Fig 6A) and RPE cells ... SH-SY5Y cells from injury in the presence of neurotoxinsFigure 1 RPE-CM protect SH-SY5Y cells from injury in the presence of neurotoxins. (A) SH-SY5Y cells cultured without rotenone (Control), cells ... brain injection on a stereotaxic frame (Myneurolab, USA). 6-OHDA (6 μg in 3 μl) was dissolved in normal saline containing ascorbic acid (0.2 mg/ml), and injected into the right medial forebrain...

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... GVHD is initiated, T-cells produce additional proinflammatory cytokines, including tumor necrosis fac- tor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-2, which in turn attract more T-cells ... (Th2) cells can initiate a response against autoantigens leading to B -cell hyperre- activity and production of autoantibodies, causing target- organ damage, including skin, mucosa, eyes, joints, ... Consensus recom- mends a system for scoring chronic GVHD manifestations in organs and sites, including the skin, mouth, eyes, gastro- intestinal tract, liver, lungs, joints and fascia, genital tract,...

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Ngày tải lên: 18/02/2014, 04:20

... Rehabilitative Interventions in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation 557 M. Jarden New Advances in Stem Cell Transplantation 34 transplantation in a Brazilian ... re g ulator Oct4. Lin 28 Conserved RNA bindin g protein and stem cell marker. Inhibitor of microRNA processing in embryonic stem (ES) and carcinoma (EC) cells. Table 1. Combinations of the ... medicine or reparative medicine. During this last decade, the number of published articles or books investigating the role of stem cells in cell transplantation or regenerative medicine increased...

Ngày tải lên: 20/02/2014, 08:20

... to sickle cell trait includes proliferation retinopathy, worsening of diabetic retinopathy, stroke, myocardial infection, leg ulcers, vascular necrosis, arthritis of the joints and increased ... 1910 (Durham 1991). Sickle cell anemia is a type of sickle cell disease in which there is a single point mutation on the β-globin gene. Sickle cell anemia (SCA) and Hemoglobin SC disease (HbSC) are ... of the bends from driving although there is no convincing evidence that sickle cell trait increases the incidence of these problems. Lesi (1982) identified some types of sickle cell crises as hemolytic...

Ngày tải lên: 12/02/2014, 19:20

... JS. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. J Immunol Methods 1993; ... first observed in dogs, resulting from Ab induced to HuG-CSF crossreacting against canine G-CSF (38) (Table 3). Dogs administered HuG-CSF developed an initial neutrophilia, but with ongoing HuG-CSF administration, ... an increase in the proportion of Gr-1+ cells that have initiated apoptosis as detected by mercocyanine 540 staining (42). G-CSF deficiency results in increased susceptibility to pathogens including...

Ngày tải lên: 16/02/2014, 07:20

... antibiotics may be treated with clarithromycin or clindamycin * Other antibiotics used in other centres include amoxicillin and erythromycin-sulfamethoxazole. In making the recommendations above the ... penicillin prophylaxis, the possibility of Haemophilus influenzae type B infection, and the incremental benefits of these agents in our setting in patients who have broken through penicillin prophylaxis. ... Monitoring Children receiving IV morphine must be carefully monitored for signs of opioid toxicity which may include: hypotension, bradycardia, drowsiness, coma, pinpoint pupils, cold clammy skin,...

Ngày tải lên: 05/03/2014, 12:20