health systems financing the path to universal coverage framework
báo cáo khoa học: " A win-win solution?: A critical analysis of tiered pricing to improve access to medicines in developing countries" pptx
... years; the beginning and tail prices are roughly double the GAVI price GSK has also agreed to transfer technology to the Brazilian public manufacturer BioManguinhos to produce the vaccine by the ... in the public or private sector, and private sector customers are not necessarily wealthier than those who rely on the public sector For example, over 70% of the TB drug market in India and the ... Globalization and Health 2011, 7:39 http://www.globalizationandhealth.com/content/7/1/39 only one other protease inhibitor (PI), atazanavir (ATV), which must be taken together with ritonavir but is...
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Herbal Antibiotics Natural Alternatives for Treating Drug-Resistant Bacteria doc
... are still small numbers of them that can reproduce again into the billions if you stop the antibiotics These growing bacteria, because their ancestors were exposed to the antibiotic you are taking, ... penicillin to protect itself from aggressive bacteria? How about the many other members of the ecosystem that taught us to make many of the antibiotics we use? How are they faring? And how about the health ... all life they adapt to threats to their survival Not only are some bacteria naturally immune to antibiotics, but all of them respond remarkably quickly to changes in their environment They are...
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Báo cáo y học: "Percutaneous laser disc decompression for thoracic disc disease: report of 10 cases"
... lateral to the midline of the spine Caution was necessary due to the lung fields being close to the needle entry site, increasing the risk of pneumothorax Once the entry site was determined, the ... facet joint pain as the underlying cause The patients had positive discograms that correlated to their pain; in the case of the individual with radicular symptoms, 156 she had total relief of her ... of symptoms with palpation The pain was either centralized or radiating to one side There was no facet tenderness present All the patients had negative facet injections, to evaluate for the possibility...
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Advances in StentTherapy for Ischaemic Heart Disease
... Ribozyme Mak Heart Migration inhibitors ECM-modulators Promote healing and reendothelisation Batimastat Prolyl hydroxylase inhibitors Halofuginone C-proteinase inhibitors Probucol BCP671 VEGF Estradiols ... and Healing • The Express2™ Stent strut thickness is 0.0052”, which converts to 0.13mm • Based on the TAXUS trials late loss values, neointima would be sufficient to completely cover the stent struts ... Healing • The Express2™ Stent strut thickness is 0.0052”, which converts to 0.13mm • This is well within the amount of late loss of a bare metal stent, suggesting complete stent strut coverage...
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Tài liệu Báo cáo khoa học: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters docx
... of the flap regions in the structures The complexes with APV are in cyan, and the complexes with SQV are in gray The arrow indicates the shifts between Ca atoms at the residues 50 and 51 in the ... chains, especially due to their location at the active site, as described in [28] The accuracy in the atomic positions was evaluated by the diffraction data precision indicator (DPI), which is calculated ... taken together, strengthen the suggestion that loss of the C-HÆÆÆO interaction of residue 50 with the hydroxyl of Thr80, as well as loss of hydrophobic contacts with inhibitor, are important for the...
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Tài liệu Báo cáo khoa học: Progress for dengue virus diseases Towards the NS2B–NS3pro inhibition for a therapeutic-based approach ppt
... via the histidine to the serine The transfer of the Ser Oc proton to the histidine converts the serine into a strong nucleophile for the attack on the peptidyl carbonyl of the substrate The substrate ... substrate The binding site of the NS2B cofactor could be examined for a view to inhibitor development, and competitive inhibitors of the binding site might be able to inhibit the correct fold of the ... in assisting the folding of NS3pro to the active conformation [105,107] A new construct of the recombinant form of the NS3pro fused to a 40-residue cofactor and corresponding to the hydrophilic...
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Tài liệu EXTERNAL SYMPTOMS FOR DIAGNOSING POULTRY DISEASES ppt
... Nutritional deficiencies-pantothenic acid or biotin Nutritional deficiencies-vitamin D or calcium-phosphorus imbalances White coat over tongue and Wet form of fowl pox in mouth Mycotoxins; chemical injury ... disease (for any length of time) Genetic Feet Symptom Joints fixed Swollen foot pad Toes curled Foot pad cracked, dermatitis Bird walks on toes Toes twisted Possible Cause Tenosynovitis Infectious ... dermatitis, exudative diathesis Erysipelas; fowl cholera Erysipelas; scab; gangrenous dermatitis Self picking, inflicted by other birds Hemmorhage; arthritis; gangrenous dermatitis Northern fowl mite;...
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Tài liệu Báo cáo Y học: Receptor crosstalk Implications for cardiovascular function, disease and therapy ppt
... vasoconstrictors, such as catecholamines and angiotensin II (Ang II), neural regulatory mechanisms, sympathetic vasodilator systems and the vagal tone Locally, the ability of the heart to maintain ... that the ability to concomitantly couple to PLC via the Gi and Gq pathways furnishes at least an auxiliary intraregulatory mechanism that can be mobilized to switch from one pathway to another to ... coupling to the Gi protein, indicating that the former pathway may regulate the b-AR signalling downstream of agonist–receptor interactions [10,14] These studies led to the appreciation of the probability...
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For Chronic Kidney Disease: Evaluation, Classification and Stratification doc
... approved by the Board of Directors of the NKF FRAMEWORK The Work Group defined ‘‘chronic kidney disease’’ to include conditions that affect the kidney, with the potential to cause either progressive ... modifications appropriate to the goals An Evidence Review Team was appointed by the NKF to collaborate with the Work Group to conduct a systematic review of the literature on which to base the guidelines ... that the Work Groups charged with developing the guidelines would be the final authority on their content, subject to the requirements that they be evidence-based whenever possible, and that the...
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FACING THE REALITY OF DRUG-RESISTANT TUBERCULOSIS: CHALLENGES AND POTENTIAL SOLUTIONS IN INDIA pot
... research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has ... of the planning committee, the Forum, the IOM, INSA, or ICMR; however, they have provided valuable input to the Forum and to the IOM and the workshop contributors as they deliberate on future ... identified at the community level and then referred to the district TB officer, who collects a sample from the patient and sends it to the culture and DST laboratory The culture and DST laboratory communicates...
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Medicines for Reproductive Health: Ensuring Access to Quality Assured Products potx
... Introduction At the turn of the millennium, world leaders gathered to ratify the Millennium Development Goals (MDGs) Despite the fact that it took a further six years to include the target of universal ... know or not want to know how they may need to upgrade their facilities and processes Furthermore, their national regulatory agencies may not have updated their GMP requirements and therefore are ... difficult to ascertain what had been the comparator products used and how the investigators applied Good Clinical Practice (GCP) in the conduct of the studies or Good Laboratory Practice (GLP) for the...
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INFLUENZA VIRUS a model for learning about disease
... RNA The capsid and the nucleic acid together are called the nucleocapsid Fully formed virus that is able to establish an infection in a host cell- virion Figure 6.4 The Viral Capsid: The Protective ... into proteins Negative-sense RNA: genomes have to be converted into the proper form to be made into proteins Segmented- individual genes exist on separate pieces of RNA Other Substances in the ... into a suitable host cell Stimulate the immune system to produce antibodies that can protect the host cells against future infections Nucleic Acids: At the Core of a Virus Genome- the sum total...
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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx
... was found in the upper part of the tract including the epithelial cells of the tongue, esophagus and stomach, where it was expressed from the cardiac to the pyloric region, down to the gastroduodenal ... lipid peroxidation [21] In the light of these observations, the detoxification systems in the epithelial lining of the GI tract deserve further investigation as to their possible etiological roles ... complementary, rather than overlapping patterns The Adh1 signal was restricted mainly to the neck of the gastric gland, whereas Adh4 was restricted to the gastric pit closer to the lumen At the gastroduodenal...
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Managing drug resistant tuberculosis ppt
... been culture negative for six continuous months Other second line agents to make the total number of drugs to which the isolate is susceptible up to four or five (table 1) TIPS FOR NON-SPECIALISTS ... referred to the local tuberculosis service The patient failed to attend his first two appointments at the tuberculosis clinic He had a history of substance misuse and several convictions for theft ... most tuberculosis in the UK is acquired outside the country.10 11 If the strain in the north London outbreak had been more extensively resistant, the consequences for public health would have been...
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Radiological Findings of Extensively Drug-Resistant Pulmonary Tuberculosis in Non-AIDS Adults: Comparisons with Findings of Multidrug-Resistant and Drug-Sensitive Tuberculosis docx
... on the monitors for analysis zone if they were located cephalad to the aortic arch, in the lower zone if they were located caudad to the inferior pulmonary vein and in the middle zone if they ... 40detector row scanner was used for five patients (Brilliance 40, Philips Medical Systems, Best, The Netherlands) and a 64-detector row scanner was used for five patients (Aquilion, Toshiba, Tokyo, ... 13), to the best of our knowledge, the imaging findings of XDR TB have not been reported Thus, the purpose of this study was to describe the radiological findings of XDR pulmonary TB and to compare...
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Safe and Effective Medicines for Children: Studies Conducted Under the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act potx
... research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has ... for example, to the “12- to 16- year” age group whether it is referring to children from the ages of years up to but not including 12 years or to children from the ages of years to 12 years inclusive ... strategies to meet these challenges To improve pediatric studies of drugs and biologics and their evaluation, it is important for FDA to continue to expand initiatives to strengthen the science...
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Báo cáo khoa học: Amyloid–cholinesterase interactions Implications for Alzheimer’s disease pot
... addition, other molecules with dual acetylcholinesterase inhibitor activity have been developed from tacrine The acetylcholinesterase and butyrylcholinesterase inhibitory activity, together with the ... required to block the acetylcholinesterase–Ab complex than that needed to block the free acetylcholinesterase The complex with AbVal18 fi Ala showed the highest difference compared with the free ... refolding abnormally into a structure that is able to convert normal molecules of the protein into the abnormally structured form However, the term in itself does not preclude other mechanisms of...
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Addressing the Threat of Drug-Resistant Tuberculosis potx
... research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has ... of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility ... stakeholders The goals of the workshop summarized in this report were to understand the magnitude and nature of the drug resistance problem; to assess the adequacy of the current global response; and to...
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Guideline for Alzheimer’s Disease Management pdf
... right to autonomy and the caregiver’s duty to protect The PCP should assess and assist with the need for balancing these concerns with respect to such decisions as determining the time to stop ... in the rate of decline should trigger an urgent visit to the PCP • Identify the primary caregiver and assess the adequacy of family and other support systems, paying particular attention to the ... acculturation) PCPs need to be vigilant with respect to the health of the primary caregiver as well as that of the patient with Alzheimer’s Disease, whether or not the caregiver is their patient A brief...
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Delamanid for Multidrug-Resistant Pulmonary Tuberculosis pdf
... † The body-mass index is the weight in kilograms divided by the square of the height in meters ‡ The Americas region included Peru (98.3% of the patients) and the United States (1.7%) The Southeast ... for the comparison of the 100-mg group with the placebo group and P = 0.005 for the comparison of the 200-mg group with the placebo group) Furthermore, the Cochran–Armitage trend test used to ... assessments The design included an additional 4-week period of patient monitoring to confirm the sputum-culture status while patients continued to receive the background drug regimen The objective of the...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25