gsk3β tyrosine 216 and β catenin serine 45 threonine 41 phosphorylation but increased β catenin serine 33 37 threonine 41 phosphorylation in response to apf
báo cáo khoa học: " Patient- and delivery-level factors related to acceptance of HIV counseling and testing services among tuberculosis patients in South Africa: a qualitative study with " pdf
Ngày tải lên :
10/08/2014, 10:23
... responsible for developing and maintaining successful TB and HIV/AIDS control programs, in addition to securing financial and organizational support for continuous and uninterrupted supply of ... TBHIV interclinic referral; poor service integration and recording; logistical shortages; and high costs of services Another South African study [16] identifying constraints to integrating TB and ... personnel and professionals Suggestions to alleviate this problem included increasing the number of healthcare facility staff, improving training for professional and lay health workers, and integrating...
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The impact of and responses to HIV/AIDS in the private security and legal services industry in South Africa potx
Ngày tải lên :
22/03/2014, 18:20
... business impact of HIV/AIDS and responses thereto Both Studies and in each sector were preceded by a formative study involving interviews with managers or key people involved in HIV/AIDS in a ... written into the policy, and dedicated staff and funding Introduction 1.1 Background Free download from www.hsrcpress.ac.za In October 2005, the Safety and Security Sector Education and Training ... employees in 34 workplaces involved mainly in mining and manufacturing in Botswana, South Africa and Zambia during 2000–2001, found a national prevalence rate of 14.5% in South Africa and showed...
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Báo cáo y học: "Antiretroviral therapy at a district hospital in Ethiopia prevents death and tuberculosis in a cohort of HIV patients." ppt
Ngày tải lên :
10/08/2014, 05:20
... care and treatment The hospital has been doing HIV counselling and testing since the early 1990's and since January 2002, the services include basic tests to deliver antiretroviral drugs (ARVs) and ... 38.7%) followed by skin rash (41/ 124, 33. 1%) and anaemia (11/124, 8.9%) Two men taking an EFV containing regimen developed breast enlargement One patient, taking a d4T-containing regimen, died ... done when clinically indicated Identified opportunistic diseases were treated according to the standard in the hospital We repeated clinical examinations and CBCs every 12 weeks and encouraged...
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báo cáo khoa học: " The Chinese government’s response to drug use and HIV/AIDS: A review of policies and programs" potx
Ngày tải lên :
11/08/2014, 18:20
... government-supported pilot MMT clinics were established in five provinces in early 2004 [23,30] The program has since grown to 320 clinics, serving a total of 27,000 heroin users in 22 provinces [28] By November ... control, incarceration, voluntary counseling and testing and harm reduction intervention Results Current policies regarding drug use and HIV prevention among drug users In 1990, the Standing Office ... http://www.harmreductionjournal.com/content/7/1/4 Xinjiang, Guangxi and Sichuan provinces are 41. 31%, 16.95% and 15.12% respectively; whereas, HIV infection rates among IDUs in Xingjiang and Yunnan province reached to 52.51% [16]...
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báo cáo khoa học: " HIV/AIDS: global trends, global funds and delivery bottlenecks" ppsx
Ngày tải lên :
11/08/2014, 18:20
... aid • More rapid and reliable testing methods, including 'optout' options, better counseling programmes and facilities, and the inclusion of partners in both testing and counseling programmes • ... strengthening of health systems in order to build capacity and sustainability, thereby redressing the inequities in healthcare delivery due to historical differences in health systems between and within ... Between 2001 and 2003, the percentage of HIV-infected who are women increased in North America from 20% to 25%, and in Oceania from 17% to 19%, suggesting that gender inequalities underpin the transmission...
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Báo cáo y học: "Differential gene expression in HIV/SIV-associated and spontaneous lymphomas"
Ngày tải lên :
02/11/2012, 11:08
... protein forms, TAF-1α and TAF- 1β [31], the latter being the SET protein SET/TAF- 1β is a member of the INHAT (inhibitor of histone acetyltransferase) complex SET is also an inhibitor of protein ... Kurland JF, Meyn RE Protease inhibitors restore radiation-induced apoptosis to Bcl-2-expressing lymphoma cells Int J Cancer 2001; 96: 327 -333 128 28 Wang XD, Rosales JL, Magliocco A, et al Cyclin ... IL5: the interleukin gene; λIg: the λ-chain of immunoglobulin gene; γIg: the γ-chain of immunoglobulin gene; IFN-ind: the interferon-inducible gene 6-16; IL4R: the interleukin receptor gene; TAP2:...
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Tài liệu PEPFAR Guidance on Integrating Prevention of Mother to Child Transmission of HIV, Maternal, Neonatal, and Child Health and Pediatric HIV Services pdf
Ngày tải lên :
12/02/2014, 19:20
... Design, integrate and/ or coordinate training curricula and accompanying materials (including pre-service and ongoing in- service training) for new and existing health care providers • Support mentorship ... counseling and support, including micronutrient supplementation and deworming ● Infant feeding counseling including benefits to mother and infant of exclusive breast feeding (EBF) ● Voluntary FP, including ... capacity in two sectors for a marginal cost increase, as demonstrated in Haiti with syphilis and HIV testing training 6+ Integrating new HIV services into the existing health system and the resulting...
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Tài liệu Sexual and Reproductive Health of HIV Positive Women and Adolescent Girls: A Dialogue on Rights, Policies and Services ppt
Ngày tải lên :
13/02/2014, 10:20
... social factors surrounding this flesh and these bones ’When are we going to start entering into the male dominated universities and change the curricula and prepare medical doctors and nurses and lawyers ... counselling and testing practices need to be re-examined, and that preparation for these programmes is currently inadequate In particular, issues related to “opting in/ opting out” protocols need to be ... results in administering ARVs to both the labouring woman and newborn if needed Responding to the ethical dilemmas posed by this practice, a contributor discussed another protocol being piloted in...
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Tài liệu Báo cáo khoa học: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters docx
Ngày tải lên :
18/02/2014, 04:20
... Dashed lines indicate van ˚ der Waals interactions and dotted lines show C-HÆÆÆO interactions Interatomic distances are shown in A with black lines indicating PRWT and ˚ red lines indicating the ... Dashed ˚ lines indicate van der Waals contacts with interatomic distances in A Dotted lines indicate C-HÆÆÆO interactions Black lines indicate interactions in SQV complexes Red lines indicate interactions ... different inhibitors will give insight into the mechanisms of resistance and help in the design of new inhibitors Results APV inhibition of PR and mutants The kinetic parameters and inhibition constants...
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Failing Women, Failing Children: HIV, Vertical Transmission and Women’s Health ppt
Ngày tải lên :
05/03/2014, 13:20
... should be involved in ongoing advocacy to encourage governments to act more responsibly and consistently, including in regards to addressing stigma, discrimination and violence against women ... society to look beyond the magic bullet of administering a pill each to mother and baby in order to stem the annual toll of preventable infections and deaths in newborns care and support to mothers ... testing and counselling (PITC) was implemented in 2006 within various medical settings including prevention of vertical transmission, STI and tuberculosis clinics This has increased HIV testing...
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Reproductive Choice for Women and Men Living with HIV: Contraception, Abortion and Fertility pdf
Ngày tải lên :
05/03/2014, 17:20
... planning (including vasectomy and condoms), infertility testing and treatment (including HIV testing), sex therapy, sperm counts and hormone, urine and blood testing Men visiting the clinic for ... male and female factors accounting for 40% each, and the remaining 20% either shared or unexplained factors.92 Secondary infertility is often linked to a history of certain STIs and iatrogenic infection ... of counselling and testing for HIV into family planning services can increase access to family planning provision tailored to the needs of women and men living with HIV and possibly to dual protection.115...
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Báo cáo Y học: Functional reconstitution of the HIV receptors CCR5 and CD4 in liposomes pot
Ngày tải lên :
08/03/2014, 09:20
... corresponding sites in the polylinker region of the pcDNA3.1myc-His expression vector (Invitrogen, Groningen, the Netherlands) in order to obtain a recombinant protein containing the C-myc epitope ... expressing gp120/gp41 to proteoliposomes containing CD4 and CCR5 A: Binding of the 35 S-labelled soluble version of gp120/gp41, strain JR-FL to CD4CCR5 or only CCR5 containing proteoliposomes containing ... Linden, J (1997) Reconstitution of bovine A1 adenosine receptors and G proteins in phospholipid vesicles: betagamma-subunit composition in uences guanine nucleotide exchange and agonist binding...
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Comparing HIV prevalence estimates from prevention of mother-to-child HIV transmission programme and the antenatal HIV surveillance in Addis Ababa docx
Ngày tải lên :
15/03/2014, 10:20
... HIV were 66% in 2004, 33% in 2005, 40% in 2006 and 52% in 2007 Following the introduction of routine opt-out testing approach, 75% of the antennal attendees in 2008 and 84% in 2009 were tested ... supervising the data collection and reviewing the manuscript SGH was involved in developing the study proposal and reviewing the manuscript MMS was involved in supervising the data collection and ... surveillance report and has potential to monitor HIV prevalence trends Our findings showed that the proportion of women testing in PMTCT programme increased markedly especially following the introduction...
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Interventions linking gender relations and violence with reproductive health and HIV: rationale, effectiveness and gaps pptx
Ngày tải lên :
22/03/2014, 12:20
... is amenable to change The attitudinal and behavioural constellation constituting femininity and masculinity are acquired and perpetuated by evolving socio-cultural and contextual factors which ... mothers accessing antenatal care in public clinics Approach: Clinic-based couples counselling addressing male partner involvement and support in maternity, STI and HIV prevention Stepping Stones Background: ... educators, coordinators and men who have participated in the workshops, indicate that the programme has been effective in increasing knowledge of HIV/AIDS, changing gender attitudes and norms and...
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Báo cáo khoa học: Peptides that bind the HIV-1 integrase and modulate its enzymatic activity – kinetic studies and mode of action pptx
Ngày tải lên :
22/03/2014, 16:21
... of these, LEDGF 36 1370 and LEDGF 40 1413 , were derived from the loops binding LEDGF p75 to IN, and were found to be inhibitory [54] Two other INinhibitory peptides, Rev 1323 and Rev 5367, were ... of IN and its DNA substrate or inhibit the initial INDNA binding, an observation that explains their inhibitory properties A signicant decrease in Vmax and Kcat values and a slight increase in ... IN- binding domains for the various IN- interacting peptides Binding of the various IN- interacting peptides to an IN- derived peptide library was estimated by an ELISAbased system as described in...
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Báo cáo khoa học: Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir-binding site potx
Ngày tải lên :
23/03/2014, 12:20
... main chain atoms of residues 16¢)18¢, 37 41/ 37 )41 , 43¢)46¢, 70¢)71¢ and 81 (Fig 5) The estimated main chain errors were ˚ ˚ 0 .37 A for Pro81 and 0.16–0.32 A for the other residues, ˚ suggesting ... improved interactions with indinavir In contrast, PRL90M showed fewer van der Waals contacts with indinavir, the main chain atoms of residues 80–82 were further from the indinavir, and the side chain ... atom of indinavir interacted with the carbonyl oxygen of Gly27¢ The indinavir O1 and O3 atoms formed hydrogen bond interactions through a water molecule (OA) to the amides of Ile50 and 50¢ Indinavir...
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Báo cáo khoa học: HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment ppt
Ngày tải lên :
30/03/2014, 13:20
... methods Materials Gp41(24–157) Recombinant ectodomain of gp41 corresponding to amino acids 537 669 of the envelope protein of the LAI isolate (p 0 337 5) with a C-terminal extension of amino acids GGGGSHHHHHH ... corresponding to helix N containing a C-terminal extension encoding the first six amino acids of the helix C and a fragment corresponding to helix C containing an N-terminal extension coding for ... recombinant gp41(24–157) containing the cysteine residues The potent HIV entry inhibitor 5-helix [25], a recombinant gp41 trimer lacking a helix C, has been shown to bind tightly to individual C...
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báo cáo sinh học:" Health workers'''' views on quality of prevention of mother-to-child transmission and postnatal care for HIV-infected women and their children" docx
Ngày tải lên :
18/06/2014, 17:20
... hospital in Thailand that peer counsellors can work in hospital to help health workers doing some administration work, providing counselling, making appointments We may need to think about how to apply ... in nine health facilities, in waiting rooms, counselling rooms, ANC examination wards, delivery wards, postnatal wards, outpatient and inpatient clinics for ARV and OI facilities, and laboratories ... to have advanced PMTCT training All of them asked to be updated routinely on PMTCT "Although training has often been provided to doctors but not nurses, in fact training should be conducted more...
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Báo cáo hóa học: " Sargassum fusiforme fraction is a potent and specific inhibitor of HIV-1 fusion and reverse transcriptase" pot
Ngày tải lên :
20/06/2014, 01:20
... of HIV-1 binding and replication Inhibition of HIV-1 binding and replication GHOST cells were plate at × 105/well in 12-well plates and incubated at 37 C in CO2 atmosphere with increasing concentrations ... of SP42 fraction to directly inhibit HIV-1 binding to cellular surface receptors in culture (Fig 4) HIV-1 infection at 4°C allows only binding of the virus to cellular receptors but not membrane ... HIV-1 S fusiforme inhibits HIV-1 fusion by blocking CD4 receptor Viral entry into cells consists of two distinct steps of 1) virus binding to the cellular receptor and coreceptor, which is followed...
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