glycosphingolipids as effectors of growth and differentiation

... less-ordered’ nature of these effectors contributes to pathogenesis EspB as an effector of actin filament reorganization The EspB (or EarB) gene product was first identified as an important factor ... pedestals, as well as the role of EspB in reorganizing actin filaments and host proteins associated with cell morphology In binding to a-catenin, EspB also promotes the dissociation of a-catenin ... interactions between myosins and actins, EspB can prevent both the initiation of phagocytosis and the production of microvillus effacing [12] It has been reported that deletion of the central domain...

Ngày tải lên: 29/03/2014, 09:20

... an investigation of biophysiology and pathophysiology of cell growth and differentiation of hNESPCs isolated from xii healthy nasal mucosa and NP biopsies, and the implication of this cell model ... human and mice, the donor cells had been sorted into basal and non-basal population based on the surface marker (KRT5), and basal cells successfully showed their ability of self-renew and differentiation ... infectious agents, and air pollutants As the first line of defense, the homeostasis of the nasal epithelium is maintained by a tight balance of stem cell self-renewal and differentiation (Holgate,...

Ngày tải lên: 09/09/2015, 11:29

... Fluorescence emission was recorded at 460 and 580 nm After a 20 sec baseline reading, 0.1 ml of PBS containing 10 µM of the compound investigated was added, and the fluorescence signal was recorder for ... biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism used by larvae of beetles (Chrysomelidae) Their synthesis has been previously ... (A) and CHO cells expressing hSGLT2 (B) was determined by IC50 assessment Different concentrations of thioglycoside I and VII in log scale were plotted against [14C]AMG uptake as percentage of...

Ngày tải lên: 26/10/2012, 10:04

... quite as independent of Hegel as of Kant, of Vico as of Spinoza Of course he has made use of the best of Hegel, just as every thinker makes use of his predecessors and is in his turn made use of ... verisimilar and of naturalism–Critique of ideas in art, of art as thesis, and of the typical–Critique of the symbol and of the allegory–Critique of the theory of artistic and literary categories–Errors ... else The doctrine of the concept and of the organism of the concepts, of definition, of system, of philosophy, and of the various sciences, and the like, will fill the place of these and will constitute...

Ngày tải lên: 07/03/2014, 12:20

... absence of style, of objective and subjective, of classic and romantic, of simple and ornate, of proper and metaphorical, of the fourteen forms of metaphor, of the figures of word and of sentence, and ... quite as independent of Hegel as of Kant, of Vico as of Spinoza Of course he has made use of the best of Hegel, just as every thinker makes use of his predecessors and is in his turn made use of ... HISTORICISM AND INTELLECTUALISM IN AESTHETIC Critique of the verisimilar and of naturalism Critique of ideas in art, of art as thesis, and of the typical Critique of the symbol and of the allegory...

Ngày tải lên: 08/03/2014, 12:20

... (and Y454) can be phosphorylated by a recombinant version of the Src-family kinase c-Fyn Regulation of actin assembly by Tir and EspFU Fig Regulation of actin assembly by EPEC Tir Clustering of ... Tir and binds WASP ⁄ N-WASP to promote actin assembly Two independent studies, one that employed a genome-scale loss -of- function approach [53] and another Regulation of actin assembly by Tir and ... formation and pathogenesis As long as pedestal formation continues to support our ability to learn about the regulation of actin assembly and plasma membrane dynamics, the study of Tir- and EspFU-mediated...

Ngày tải lên: 29/03/2014, 09:20

... EspL2 and Annexin A2 [8] Annexin A2 binds to the cytosolic surface of the cellular membrane and this has been linked to the formation or stabilization of actin assembly sites [9] Localization of ... Identification and cloning of a novel plasmidencoded enterotoxin of enteroinvasive Escherichia coli and Shigella strains Infect Immun 63, 4721–4728 Abe H, Miyahara A, Oshima T, Tashiro K, Ogura ... known as annexin II) may be the target of EspL2 in host cells Coprecipitation of Annexin A2 with EspL2 from a purified mixture of the two in vivo supported the interaction of both proteins and, ...

Ngày tải lên: 29/03/2014, 09:20

... proteins ASYMMETRIC LEAVES1 (AS1 ) and AS2 and the chromatin-remodeling factor HIRA AS1 and AS2 form a repressor complex that binds directly to two DNA motif sites that flank the enhancer element of ... proteins such as CTCF may have acquired additional functions with increased complexity of the genome (reviewed in [4]) In yeast (S cerevisiae), which has a haploid genome size of 13 megabases, the ... thaliana, binding of the ASYMMETRIC LEAVES1 (AS1 ) -AS2 complex at two specific DNA sites flanking the enhancer is required to silence the expression of the BP gene Recruitment of the histone chaperone...

Ngày tải lên: 06/08/2014, 19:20

... (previous years growth + spring growth) and from bud scar to terminal bud (second ush of growth) The whole root, the whole stem of each ush and a sub-sample of preformed and neoformed leaves were ... activity was assayed by monitoring the decrease in absorbance at 340 nm in an assay system coupled with malate dehydrogenase (E.C 1.1.1.37) at 30 C The assay medium was based on that of Tietz and ... the growth and (2) the response of major enzymes of the catabolic pathways of sugar maple seedlings exposed to an extensive gradient of O3 , from to 300 nL.L1 MATERIAL AND METHODS 2.1 Growth of...

Ngày tải lên: 08/08/2014, 00:22

... progeny of each of provenances of blackjack oak (Quercus marilandica Muenchh) was tested in southeastern Pennsylvania The provenances were in Texas, Kansas, Arkansas and New Jersey Height growth ... Provenance variation has been studied in eastern Nebraska and on a smaller scale in eastern Pennsylvania and Ohio Variation in growth rate In eastern Nebraska, sampled the a test of 50 seed species ... pattern of growth rate (Dicke and Bagley, 1980) In eastern Pennsylvania, only seedlots each from Kansas, South Dakota and Minnesota were tested Height growth tended to increase with decreasing...

Ngày tải lên: 08/08/2014, 19:21

... crown and the trunk of the mother trees and their progenies The same was true for stands with good and bad form Oppermann gave the frequency distribution for progenies of good and bad stands at ... sections of this paper Hybridization mosaic pattern of dry and wet areas as in the mountainous regions of Germany, both species are sympatric and show intensive introgression a Leaves A discussion of ... constituted a valuable base for human life in the past The fruits served as a nutritional base for their animals and the wood was invaluable for construction, tools and shipbuilding Oak was therefore extensively...

Ngày tải lên: 08/08/2014, 19:21

... was uniformly scanned up and down and from side to side of the sunfacing side of each sample tree for ≈ 20 s Just prior to each of these measurements, another integrated measure of PPFD was ... total biomass of the stem and branches of each crown section in order to estimate stem and branch growth for each of the years Light measurements On cloudless days during each growing season, the ... Furthermore, the basal area growth for 1988 and 1989 was calculated for each of the crown sections and its percentage in relation to the total basal area was calculated This factor was applied to...

Ngày tải lên: 08/08/2014, 23:21

... goodnessof-fit of TIMP-1, lactic acid, and SOFA scores as criterion variables and mortality as the response variable Relative risk and 95% confidence intervals were calculated as measurements of the ... levels of TIMP-1, reduced Figure and SOFA score as predictors of mortality Receiver operation characteristic analysis using TIMP-1, lactic acid, and SOFA score as predictors of mortality The areas ... specificity into collagenases (MMP-1, -8, and -13), gelatinases (MMP-2 and -9), stromelysins (MMP-3, 10, -11), elastases (MMP-7 and -12), and membrane-type (MT-MMPs, MMP-14, -15, -16, and -17) MMPs have...

Ngày tải lên: 13/08/2014, 19:20

... gardens often assumed to (and ought to) be inclusive? Can we posit community gardens to be necessarily both spaces of inclusions and exclusions, and why? Instead of reifying the simple (and almost ... systems of government through community Exclusion, then, emerges as the “outcome of a mismatch between the norms, aspirations, and communication through threads of social power and control, and the ... framework of this thesis 2.2 Urban community gardens as research space 2.2.1 Community gardens: spaces of inclusions and community bonding There has been a long and rich history of practices associated...

Ngày tải lên: 07/10/2015, 10:10

Ngày tải lên: 14/10/2016, 13:21

... 2002, Thailand Results and Discussion Damage symptom of vegetables by As and Cd As phytotoxicity was shown by growth retardation of radish and lettuce whereas Cd phytotoxicity was shown by growth ... kg-1 of As treated soils As the concentrations of Cd and As in soils were increased, the contents of Cd and As in agricultural products were significantly increased, basically The contents of Cd ... yield of the edible part of chinese cabbage, radish, and lettuce grown at the Cd treated soils Contents of As and Cd in edible part of chinese cabbage, radish, and lettuce The contents of As and...

Ngày tải lên: 16/03/2014, 00:07

... behavior of gold and indium on Si(1 1) has been described and analyzed An explanation based on differences of solubilities of surface atoms in gold and indium and on the different surface energies of ... effects of different diffusion coefficients of gold and indium on silicon, the solubility of substrate atoms in the two metals, the surface tension of gold and indium and the surface energy of silicon ... bare and oxidized substrate as well as on the surface tension of the liquid metal alloys has been presented Silicon nanowires have been grown via VLS mechanism with the use of gold and indium as...

Ngày tải lên: 16/03/2014, 15:17

... export basket By this measure and using Reserve Bank of Zimbabwe (RBZ) data on the portfolio of product exports, the export basket of Zimbabwe has become markedly more concentrated during the past ... Potential, and Problems Table 1.1  Growth of Extensive and Intensive Margins in Zimbabwean Exports and Imports Percentage change from base year Intensive margin Growth Net growth of initial year ... trade as an engine of growth Two bright spots in recent performance are underscoring the promise of Zimbabwean exports for future growth: the surge of mining exports and the emergence of China as...

Ngày tải lên: 25/08/2016, 14:29

... hydrolysis of cellulose microfibrils to release glucose involves synergistic action of three enzymes: endo-glucanase, exo-glucanase and β-glucosidase Endo -and exo-glucanases are commonly referred to as ... pretreatment [22] Degree of lignification and ash content are direct indicators of quality of biomass feedstock As wheat straw leaves contain more ash than other components and nodes are high in ... metals such as sodium and potassium [47] Burning biomass for production of electricity rather than using it as a feedstock for production of biofuels would lead to its greatest utilization as an energy...

Ngày tải lên: 05/09/2013, 15:28

... development of ideas and information, a high degree of accuracy so that there is no ambiguity of meaning, the use of complex grammatical devices for focus and emphasis and a careful choice of vocabulary, ... understanding of the topic and had added benefit of creating a feeling of common ownership of results Table 8: The reasons for the approval of the application of brainstorming in the future As can ... ideas in a variety of ways 10 Having a range of vocabulary As can be seen from the diagram above, ideas and a range of vocabulary are always demonstrated by writers If writers have poor ideas and...

Ngày tải lên: 18/12/2013, 10:08