genetic variation in host defenses and viral infections

... are shown in Appendix (equations (1) and (2)) Variation in body maintenance was introduced via the coefficients pmaint and emaint , associated with protein and energy requirements for maintenance, ... traits in sheep infected with gastro-intestinal parasites were examined Altering genetic relationships between underlying input traits and preferences in the allocation of available dietary protein ... found in Vagenas et al [26, 27] Between-animal variation was assumed in animal intrinsic growth abilities, in maintenance requirements, and in animal ability to resist or cope with gastro-intestinal...

Ngày tải lên: 14/08/2014, 13:22

... (SD) and common genetic variation of NPHS1 may influence SD function in diabetic nephropathy (DN) More recently, NPHS1 has also been reported in pancreatic β-cells and was involved in insulin secretion ... corroborating evidence for this earlier finding in Singaporean Chinese patients with T2DM Furthermore, nephrinuria was found to be associated with a decline in eGFR even in normoalbuminuric patients ... renal traits including eGFR and albuminuria in T2DM Chinese patients in Singapore These patients were from the Singapore Diabetes Cohort Study (SDCS) described in Methods 2.1.1 Aim 2: To investigate...

Ngày tải lên: 03/10/2015, 20:58

... the succeeding life stages The genetic multiplicity was very large in all samples investigated including single-population samples This finding concurs with results of a recent study in 32 European ... Particularly in oak species, it appears that large genetic variation should be incorporated in productive populations in order to maintain the potential of these populations to adapt to and to survive in ... the origin of the studied samples, see Müller-Starck and Ziehe (1991) Genotyping proceed Genetic control and inheritance of isoenzymes verified beforehand by utilizing full-sib families and their...

Ngày tải lên: 08/08/2014, 19:21

... Ratios and CI were estimated using logistic regression adjusted for age and sex gene being involved in AD pathology, possibly through oxidation of Aβ or ApoE, promoting their aggregation into insoluble ... possible role of MPO polymorphism in the development of cognitive decline in MS This study was mainly designed to investigate whether some clinical and individual variables and the occurrence of the ... Immunohistochemical and genetic evidence of Myeloperoxidase involvement in Multiple Sclerosis J Neuroimmunol 1997, 78:97-107 Kantarci OH, Atkinson EJ, Hebrink DD, McMurray CT, Weinshenker BG: Association...

Ngày tải lên: 11/08/2014, 08:20

... additive and dominance index values for the relQTL (Xar, Xdr), the additive and dominance index values at other locations (Xa, Xd), and the interactions of the two sets of index values These interactions ... by calculating residuals from the model and adding them to the mean weight in the overall population This procedure was useful in decreasing non -genetic sources of body size variation and therefore ... traits included total daily distance (kilometers) and total daily exercise time (minutes) that were recorded every 24 h, and average daily running speed (meters/minute) obtained by dividing distance...

Ngày tải lên: 14/08/2014, 13:21

... Papua, adjacent to PNG and outlying populations in the Aru Islands and Ceram) Commonly used seed material in Vietnam plantations includes origins from provenances in both QLD and PNG (Kha 2003) Provenances ... progeny tests were established at Ba Vi in Hanoi Province and Son Duong, Tuyen Quang Province, both in northern Vietnam and Bau Bang in Binh Duong province in southern Vietnam Site conditions, experimental ... age and age 4, f is the vector of random family within genetic group effects, and e is the vector of random residuals XB ; XP ; ZW ; ZN ; ZT and ZF are incidence matrix relating m, p, w, n, t and...

Ngày tải lên: 18/08/2016, 15:47

... analysis is done by individual genetic profiling (genetic fingerprinting), determining the interrelations between different individuals and evaluating their allele frequency in populations Microsatellite ... with inbreeding coefficients in both populations and interpopulations 30 Analysis of Genetic Variation in Animals The inbreeding coefficient of the whole population (FIT = Factor of Inbreeding in ... be divided into: i) inbreeding coefficient of individuals in relation to a subpopulation which includes individuals (FIS = Factor of Inbreeding relative to subpopulation); ii) inbreeding coefficient...

Ngày tải lên: 28/06/2014, 08:20

... RA, and ARD, respectively (including all data and no family discrimination) TWR decreased as ring number increased The maximum and minimum values were 15.6 mm, at ring 3, and 3.5 mm, at ring ... in radiata pine decreased from the pith outward until a minimum was reached about the ninth growth ring from the pith followed by an increase in genetic control with further increase in age In ... Figure Average values and standard errors for (A) tree ring width (TRW); (B) ring area (RA) and (C) average ring density (ARD) by cambial age 545 Genetic variation of ring density and growth A Table...

Ngày tải lên: 08/08/2014, 14:20

... years of ageing and roburin C over the first 30 years, before each declines again in older wood Grandinin and roburin E show less clear patterns, but in general concentrations remain approximately ... vescalagin and castalagin may transform directly or indirectly to dimers The rapid decline in vescalagin corresponds with an increase in concentrations of these dimers Roburin D (vescalagincastalagin) ... ellagitannins (fig 1) Purified samples of vescalagin, castalagin, grandinin and roburin A (kindly provided by Dr Scalbert, INRA, Paris) allowed confirmation of their identification and were used...

Ngày tải lên: 08/08/2014, 18:21

... regions was of minor imwas portance MATERIALS AND METHODS (for details see Aas, 1988) Oaks chosen from 30 different stands in and Poland (stands of pedunculate oak, sessile oak and mixed stands; the ... 0=extremely cordate to 4= tapering); 7) number of lobes; 8) sinus-veins (relative frequency of lateral veins running to sinuses in the middle portion of the leaf; values obtained ranged from to 1.0 ... of lamina (mm); 3) width of lamina (mm); 4) shape of lamina (width at 0.25 length of lamina / width at 0.75 length); 5) depth of sinuses (index value); 6) leaf base (5 shape values ranging from...

Ngày tải lên: 08/08/2014, 19:21

... unreliably stained and could not be considered The more cathodal zone exhibits bands differing in mobility and staining intensity In addition, a null allele was observed Thus, this zone was interpreted ... for L laricina (Cheliak and Pitel, 1985; Ying and Morgenstern, 1990) and at IDH for L laricina (Cheliak and Pitel, 1985) as well as for L occidentalis (Fins and Seeb, 1986) Lewandowski and Mejnartowicz ... segregation ratios and close analogy to results from other isozyme investigations in larch (Cheliak and Pitel, 1985; Fins and Seeb, 1986; Lewandowski and Mejnartowicz, 1990a, b; Ying and Morgenstern,...

Ngày tải lên: 08/08/2014, 23:22

... felling regeneration and the tropical shelterwood system were adopted Survival and growth of seedlings from different species were on studied under different thinning intensities The variations in ... species and its relative place in a forest succession It therefore seemed of interest to further the knowledge on these species by studying morphological variations in leaves and branching pattern in ... the beginning of the shading experiment, there were between 30 and 40 plants per species and per treatment The number of plants remaining at the end of the experiment is given in tables II and III...

Ngày tải lên: 08/08/2014, 23:22

... as calpains This system is involved in some growth and Genetic variation in local Romanian pigs 423 metabolic processes [7] There is evidence for the decreasing activity of CAST with age and a ... is the most prevalent in the Landrace (0.72), Pietrain (0.67) and Duroc (0.63) This genotype was absent in Chinese breeds [7] and is relatively low in the Bazna (0.38) and Mangalitsa (0.27) breeds ... prolificacy and was also found in commercial dam lines of Large White origin [32] It is assumed that it is derived from early importation of Chinese pigs into England prior to the 1800s and crossbreeding...

Ngày tải lên: 09/08/2014, 18:21

... between strains at synonymous and amino-acid-altering sites and given that about 70% of coding sites are amino-acid altering Thus, 82% of hybridizations should contain no mismatches The remaining probes ... protein response, including protein disulfide isomerase, PDI1 [28], which is required for oxidative protein folding in the endoplasmic reticulum [29] These genes, in addition to functioning in ... Protein folding Stress response Stress response RNA binding Inorganic cation transporter Cell growth and/ or maintenance 35S transcript processing Cell-wall organization and biogenesis Protein folding...

Ngày tải lên: 09/08/2014, 20:20

... role of TIMP proteins in inhibiting effects of metalloproteases SNPs in these genes can conceivably play a role in COPD development Unraveling the genetics of MMPs and TIMPs in COPD development ... 0.03, TIMP1 Ile158Ile in males 0.01, in females 0.01, and TIMP1 Phe124Phe in males 0.50, and in females 0.53 All SNPs were in Hardy Weinberg equilibrium The SNPs in MMP9 were in high LD (r2 >0.8) ... with FEV decline, but this was not replicated in the second independent population, indicating that the role of genetic variation in MMP2 on rate of FEV1 decline is still debatable In contrast...

Ngày tải lên: 12/08/2014, 13:22

... The findings in the present study indicate that certain genetic variation in this gene is influencing the occurrence of allergic rhinitis Altogether, this renders the S100A7 protein a good candidate ... at amino acid position 28 This SNP is located in exon and is coding for the N-terminal EF-hand In contrast to most of the other S100 proteins, S100A7 is not able to bind calcium in this EF-hand ... protein has previously been suggested to play a role both in innate immunity and in allergic inflammation [6,7,23] and we have detected marked differences in the levels of this protein in nasal...

Ngày tải lên: 12/08/2014, 15:21

... TGLA227, HEL5, HEL9, and BM315 in Jinnan, BM2113 and HEL13 in Chinese Holstein, TGLA227 in Luxi, INRA005 in Jiaxian, and HEL9 and INRA005 in Yanbian, which were in Hardy-Weinberg equilibrium (P ... Relationships and origin of Chinese bovine breeds In Bovine Breeds in China, published in 1986, 28 Chinese native breeds were classified into three groups i.e humpless, semi-humped, and humped types ... the genetic diversity in Chinese bovine breeds The mean PIC content in the eight studied populations was between 0.85 and 0.90, the Chinese Holstein breed showing the lowest value and the Qinchuan...

Ngày tải lên: 14/08/2014, 13:21

... understanding of native pinewood biology in Scotland In addition, policy recommendations concerning the seed sourcing of Scots pine in Scotland will be made 29 Mating system in Scots pine (Pinus ... documented variation in levels of inbreeding depression within larger populations in Finland: outcrossing rates in northern populations were somewhat lower than in the south, but inbreeding depression ... the maintenance of healthy pinewoods in Scotland that the patterns of adaptive variation in Scots pine across the country are investigated and taken into account when defining transfer guidelines...

Ngày tải lên: 30/09/2015, 05:57

... strains Group 1, infected with strain A, showed a very large decrease in viral load within nine weeks of infection whereas group 2, infected with strain B, maintained high viremia One major finding ... whereas HIV research is gradually turning to the investigation of more intrinsic interactions between host and viral proteins Session 4: Viral infection and innate immunity Chairs: C Soderberg-Naucler ... postinfection The following observations were made in SIVagm-infected AGMs: 1)A significant increase in TGFb1 and Foxp3 gene expression beginning in the first week after infection, coinciding...

Ngày tải lên: 13/08/2014, 09:21

... pair with specific viral mRNA targets AS-ONs inhibit viral protein production by both blocking viral mRNA translation and triggering its degradation Since the discovery of viral inhibition effect ... of rhinovirus serotypes in human cells in vitro [1921] Administration of soluble ICAM-1 and MAbs in human clinical trials had indeed achieved reduction in symptoms, but did not prevent the incidence ... targeting on viral mRNA Targeting viral mRNA is one of the most active areas of research and development Several strategies have emerged over the years and are being tested pre-clinically and clinically...

Ngày tải lên: 18/06/2014, 22:20