genetic effects of contaminant exposure and potential impacts on animal populations

... studies and murine studies [14] the expression of OPN was not inhibited by treatment with FP This lack of inhibition of OPN expression has also been observed in the serum, bronchial tissue and bronchoalveolar ... endothelial cells (glandular and vesicular) Similarly, OPN expression has Figure Percentage of osteopontin stained area in nasal biopsies pre- and peak season The percentage of the osteopontin stained ... immunohistochemical expression profile of osteopontin in normal human tissues using two site-specific antibodies reveals a wide distribution of positive cells and extensive expression in the central and peripheral...

Ngày tải lên: 08/08/2014, 21:20

... interpreted in terms of ligandinduced ATPase activation and concomitant transitions between substrate-binding and substrate-releasing conformational states The consecutive steps of the catalytic ... this question, we compared the effects of Pi analogues (Vi, BeFx, AlF4), trapping nucleotides at the catalytic site of Pgp, and of ATP depletion, on UIC2shift and UIC2/MM12.10 competition Accurate ... 2-deoxy-D-glucose The optimal concentration of Pi analogues (Vi, BeFx and AlF4) and ATP depleting agents were pretitrated in daunorubicin accumulation experiments The concentrations of the chemicals applied...

Ngày tải lên: 08/03/2014, 23:20

... change in the conformation of this loop Changes in the conformation of the backbone at this point and changes in the orientation of other side chains, as a result of the introduction of the large ... the protein was dimeric under our standard conditions of mgÆmL)1 and 15 °C Physiological conditions of ionic strength and temperature promoted the dissociation of both variants This is not surprising, ... in the CD spectrum of the wild-type enolase, which is seen on dissociation, is mimicked by a loss of W56 Discussion Fig Peptide bond CD of the monomeric and dimeric forms of wild-type yeast enolase...

Ngày tải lên: 16/03/2014, 06:20

... al of b-sheet, and even smaller amounts of a-helix [41] We therefore assume that the peptide layer on the DOPC and SM membrane surface consists of such a mixture of oligomers and secondary conformations ... membrane The large effects of SM and cholesterol on peptide insertion and aggregation are consistent with the reported occurrence of the amyloid precursor protein and Ab in neuronal membrane rafts ... high-resolution sensor Other experimental conditions were as in Fig (A) and (B) p-Polarized PWR spectra obtained for the bilayer in the presence of mM Zn ions, as a function of time, after the addition of...

Ngày tải lên: 30/03/2014, 11:20

... competition in the banking industry overall Concentration and Competition Within an existing regulatory environment and given national government control of inflation and monetary policy, competition ... adoption of e-banking Institutional factors Clients Government’s role: Regulation and infrastructure Effects of e-banking and payments infrastructure on efficiency and competition Cost and economies ... inflation and monetary policy, competition and concentration determine bank behavior and the countenance of appropriate risk levels Bank concentration and competition, both core elements of market...

Ngày tải lên: 03/06/2014, 00:59

... http://www.josr-online.com/content/1/1/9 Dose-response effect of growth factors on proliferation of human NP cells (10%FBS/F12) (n = 20) Figure Dose-response effect of growth factors on proliferation of human NP ... reduction of MTT by mitochondrial dehydrogenase to blue formazan product, which reflects the normal functioning of mitochondria and hence cell proliferation[8] Different culture conditions were ... the therapeutic potential in the treatment of disc degeneration, we investigated the effects of TGF-β1 and IGF-1 on the proliferation of human NP cells in single or combination by MTT colorimetric...

Ngày tải lên: 20/06/2014, 00:20

... i’s perception on migration and BCi is a vector of biophysical characteristics (disease/parasites and drought/famine) To model the impacts of cattle rustling and migration decision on herd size, ... cattle rustling Conclusions and implications This study intended to elucidate the effects of cattle rustling and other household characteristics on migration decisions and herd size amongst the pastoralists ... ASALs (Behnke and Scoones 1993), as it enables efficient use of rangeland resources through seasonal migration in search of pasture, water and mineral licks Thus, seasonal movement and nomadic...

Ngày tải lên: 20/06/2014, 23:20

... role of HDL has been extensively studied and is known as one of the strongest protectors against coronary artery disease [1] Consequently, the influence of PON1 polymorphism as a main component of ... HOMOZYGOTES −RR Figure Effect of paraoxonase genotype on paraoxonase activity and myocardial blood flow parameters Effect of paraoxonase genotype on (a) paraoxonase activity, (b) response to cold pressor ... ethics committee of the University of Lausanne Paraoxonase genotype and activity determination PON1 polymorphisms in positions 192 (glutamine ® arginine) and 55 (leucine ® methionine) were genotyped...

Ngày tải lên: 20/06/2014, 23:20

... amount of precipitation minus interception, infiltration, evaporation and storage losses (Hrádek 1988; Kemel 1996) First, the effects of drainage treatment and stand growth on changes in runoff ... restoration was considered as subsequence reflecting the development of regenerated forest stand Under such conditions, the fluctuation of runoff can be related to the loss and restoration of both ... the above-mentioned set of hydrographs shows a lower proportion of slow runoff (65–80%), higher proportion of accelerated runoff (17–30%) and a little lower proportion of rapid runoff (2–4%) The...

Ngày tải lên: 07/08/2014, 03:22

... a long nitridation times must be avoided because it leads to formation of AlN on the surface, which degrades the properties of the epilayer [6] 2.2 Silicon Carbide (SiC) The main advantage of ... a lattice mismatch of only 3.3% and it is very stable at high temperatures and also has excellent thermal conductivity But it is not commonly used because it is expensive and obtaining a clean ... substrate Where n s and n1, are the refractive indices of the substrate and the corresponding layer respectively, d1, is the geometrical thickness of the corresponding quarter wave layers and λ B is the...

Ngày tải lên: 07/08/2014, 14:20

... preparations of BSA could have some or all contaminants, possibly introduced during the preparation of BSA-V, removed by extraction procedures, and these contaminants may mimic the effect of serum ... alone (24.4%), phosphate alone (25.2%), and none (24.4%) 76 Kwang-taek Lim, Byeong-chun Lee, Sung-keun Kang and Woo-suk Hwang Exp Effects of glucose and/ or phosphate in s od iu m citra te Effects ... glucose concentration depends upon the culture medium; i.e., 1.0-1.5 mM in SOF [6] and TLP [11], and 5.56 mM in TCM199 The beneficial effects of co-culture included a reduced glucose concentration,...

Ngày tải lên: 07/08/2014, 17:22

... Smith F.A., Walker N.A., Effect of photon irradiance on the growth of shoots and roots, on the rate of initiation of mycorrhizal infection and on the growth of infection units in Trifolium subterraneum ... Press, Chicago and London, 1994 [19] Fetcher N., Strain B.R., Oberbauer S.F., Effects of light regime on the growth, leaf morphology, and water relations of seedlings of two species of tropical ... rapidly as soon as better conditions were restored, as observed on maize by Subramanian et al [43] and on wheat by Al-Karaki and Clark [2] Mycorrhizas seemed to affect the water relations of the seedlings,...

Ngày tải lên: 08/08/2014, 14:22

... studied in terms of emulsion stability and apparent viscosity The information obtained would provide the understanding of the function of sugar on the stability of coconut milk and could be used ... (100 magnification) of fresh coconut milk (a) and coconut milk containing 10% (b, c), 20% (d, e) and 30% (f, g) coconut sugar and 1.0% CMC and 0.8% Montanox 60 before (b, d, f) and after (c, e, ... Effects of fat and temperature on the apparent viscosity of coconut milk Journal of Food Engineering 64, 193–197 Sringam, S., 1986 Preparation and stabilization of coconut milk Food Science and Technology...

Ngày tải lên: 08/08/2014, 15:22

... assistance and cooperation of a number of individuals and organizations The staff at the California Department of Forestry LA Moran Reforestation Center were extremely helpful in rearing and maintaining ... acorns, 4-month-old seedlings and 1-yearold seedlings This project also examined the effects of trimming the radicles of germinated acorns on seedling morphology and field performance MATERIALS AND ... plot layout contained four blocks Within each block were ten rows of nine seedlings each Each row contained one randomly positioned seedling from each of the nine treatment combinations (three...

Ngày tải lên: 08/08/2014, 18:21

... Effects of high N-inputs near a chicken farm on nutrient status and vitality of Pinus sylvestris (L.) nutrient supply of P sylvestris, chemical constitution of the soil solution and NH concentrations ... causal rela- tionship between acid deposition, cation leaching, acidification of the tree’s rhizosphere, changes in soil chemistry and plant nutrition In addition to the proton deposition, N inputs ... function of acid deposition and Mg supply of the soil (Kaupenjohann, 1989) It is interesting to note that an increase of the acid load of the same soil (Fig 2) caused a higher release of both Mg and...

Ngày tải lên: 09/08/2014, 04:20

... association observed in both family- and population-based studies, replications in independent studies, and a high OR and/ or attributable risk [8] Among these criteria, validation of a genetic ... additional replications among separate sets of patients with different ethnic backgrounds, such as African and/ or Asian populations, would strengthen the confidence in any association study and ... regulation of genes induced by viral infection and immunostimulation, in addition to regulation of cell growth IRF5 was originally identified as a regulator of type I IFN gene expression [11]...

Ngày tải lên: 09/08/2014, 10:20

... significant effect on α2 expression The effects of DZ on α1, α3, and γ2 expression were the same as the effects of diltiazem on these subunits DZ sig- Gibson et al Journal of Biomedical Science ... understand the mechanism of neuroprotection, influence on cascades, and impact on behavioral outcome Evidence indicates the timing of administration of these drugs will be crucial Conclusions The ... 33) Animal care and experimental procedures were in accordance with the National Institute of Health Guide for the Care and Use of Laboratory Animals and the protocol was Gibson et al Journal of...

Ngày tải lên: 10/08/2014, 05:21

... demonstrated a direct participation of IGF2 in the reproductive function in mouse and farm animals [22,23] In addition, selection on lean growth and consequent decrease of fat percentage could reduce ... permanent environmental effect; γg = genetic correlation coefficient of NBA12 and NBA3+; γp = correlation coefficient between permanent effects of NBA12 and NBA3+ cDNA fragments of 485 and 479 bp, ... detected on exon In addition, two overlapping Muñoz et al Genetics Selection Evolution 2010, 42:23 http://www.gsejournal.org/content/42/1/23 Page of 10 γg 0.81 (0.06) and 874 for NBA3+ The number of...

Ngày tải lên: 14/08/2014, 13:21

... administration of non-coating EGFR DNA vaccine and the amount of CD8+ T cell tumor infiltration The effects of CD8+ T Cell- Depletion or CD4+ T Cell- De pletion on the Efficacy of Gene Gun Administration ... the of CD8+ T effects of non-coating EGFR DNA tion of CD8+ or CD4+cell-depletion or CD4+ cell-depleThe effectsgene gun administration (A) ProtocolTfor depleon The effects of CD8+ T cell-depletion ... mediating therapeutic efficacy of gene gun administration of noncoating EGFR DNA vaccine Discussion Figure Tumor infiltration of CD4+ and CD8+ T cells Tumor infiltration of CD4+ and CD8+ T cells Tumors...

Ngày tải lên: 14/08/2014, 19:22

... regression analysis of the effects of personal background and various dimensions of occupational stress on the QOL of Vietnamese care attendants (N = 264) Variables B Beta R2 ∆R2 t F Modelone SF-36 ... mean, and standard deviation were used to illustrate the distribution of Vietnamese care attendants based on their personal backgrounds and job responsibilities In addition, the Student’s t test and ... health and QOL Therefore, studies on the negative impact of occupational stress should focus not only on mental and physical health but also on the effects they have on QOL [10-13] Recent studies on...

Ngày tải lên: 08/08/2015, 19:23