genetic control of resistance mechanisms

... several genes [36-41] Observation of these traits contributes to a better Page of 11 Table 1: Infection models used in published studies of the genetic control of resistance to Salmonella in fowl ... Effect of genetic resistance of the hen to Salmonella carrier-state on incidence of bacterial contamination: synergy with vaccination Vet Res 2008, 39:20 Lambert W, Knox C: The inheritance of resistance ... unravelling of the Salmonella resistance genetic mechanisms The most limiting factors are and will clearly remain the fre- quent and inevitable lack of precision and reliability of phenotypic...

Ngày tải lên: 14/08/2014, 13:21

... improving wood quality in radiata pine, an understanding of the genetic variability of transition age is critical Few studies have examined the genetic mechanisms influencing transition age in fast growing ... latewood density, and latewood percentage of 9.4, 7.5 and 10.3 y, respectively; and the heritability of these traits ranged from 0.16 to 0.22 Genetic control of earlywood density, latewood density ... 20, 35, 49] The objectives of this study on radiata pine were to: (1) estimate age of transition from juvenile to mature wood; (2) quantify genetic control in time of transition from juvenile...

Ngày tải lên: 07/08/2014, 16:20

... knowledge of the role of genetics in determining a clone’s rooting ability before maturation occurs It is known from studies of rooting in other conifers that the genetic determination of rooting ... investigate the genetics control in a range of commercially important traits using genetic mapping approaches [6, 7] Rooting success of cuttings has a major impact on the cost of plantation establishment, ... sample of 144 clones from each family at each of four time points The objective of the time-course experiment was to allow timing of the assessment of rooting so that approximately 50% of clones...

Ngày tải lên: 08/08/2014, 00:22

... relationship between phenotypical and genetic values) as suggested by Keiding and Olsen [15] Another reason may be the lack of knowledge of the genetic control of traits in larch interspecific hybrids ... Standard errors of genetic parameters have been estimated by the Jacknife method [3] Genetic control of traits in larch hybrids 27 Table I Means and phenotypic coefficients of variation (CVp) ... about the possible genetic control of the main economical traits Two major aspects have been considered in this study: the first one relates to the relative genetic control of traits in hybrids...

Ngày tải lên: 08/08/2014, 01:22

... divergence of the tree from verticality At the same 565 Genetic control of wood quality Table I Definition, number of observations (n), mean value (mean) and phenotypic coefficient of variation (CVp) of ... the other fibre properties in our study In maritime pine, genetic control of fibre strength seems to be independent of the genetic control of fibre morphology Thus, if selection for fibre strength ... 44.70 37.52 38.45 36.69 34.18 43.71 39.17 46.06 567 Genetic control of wood quality Table III Decomposition of the genetic variance: significance of additive and dominance effects Source GCA df F...

Ngày tải lên: 08/08/2014, 14:20

... sialadenitis, and anti-nuclear antibodies By this strategy, the critical genetic interval, containing a gene (or genes) controlling the disease traits, could be reduced from approximately 70 to ... chromosome [1] Dissections of disease loci in models for autoimmune diseases have shown that one locus can contain more than one gene linked to disease [5,6] In one study, a locus of approximately 20 ... shared disease pathways in different models for autoimmune diseases controlled by the same genes within this interval On the basis of potential candidate genes located within the re-defined Aec2...

Ngày tải lên: 09/08/2014, 01:22

... sialadenitis, and anti-nuclear antibodies By this strategy, the critical genetic interval, containing a gene (or genes) controlling the disease traits, could be reduced from approximately 70 to ... chromosome [1] Dissections of disease loci in models for autoimmune diseases have shown that one locus can contain more than one gene linked to disease [5,6] In one study, a locus of approximately 20 ... shared disease pathways in different models for autoimmune diseases controlled by the same genes within this interval On the basis of potential candidate genes located within the re-defined Aec2...

Ngày tải lên: 09/08/2014, 13:22

... high was divided, even partially, DISCUSSION Genetic control of the ovariole number Drosophila, the study of the influence of irradiation on genesis of the female genital apparatus (Geigy, 1931; ... reduction of the number of ovarioles during the larval development, from primitive ovarioles only definitively formed ovariole This phenomenon is genetically controlled and is the result of a regressive ... start selection on the reduction of the ovariole number with this strain, in order to study the genetic control (chromosomal and epigenetical) in the determinism of to the ovariole number in Sitophilus...

Ngày tải lên: 09/08/2014, 18:21

... therapy because of the increase in the amount and survival of infused T cells found with this system Their system for the control of mammalian T-cell proliferation is based on a platform of assembled ... enhancing the persistence of transferred T cells include ablation of all white blood cells (myeloablative methods), such as total body irradiation and administration of toxic levels of interleukin (IL)-2 ... that limit the use of adoptive T-cell therapy for cancer For example, the failure of adoptive immuno­ therapy against cancers lies in the absence of tumorspecific sources of T cells [6] If such...

Ngày tải lên: 11/08/2014, 12:21

... calculated on the basis of the rate of accumulation of joint damage over a specific interval of time, and therefore an effect of I50V on severity may have been overlooked The pattern of IL-17 suppression ... IL-4R, did not control RA severity These findings suggest that a unique IL-4R polymorphism may predict disease outcome in RA Since tight control of the clinical activity of Page of RA substantially ... http://arthritis-research.com/content/13/1/R15 Page of the healthy control group genotypes There was a more pronounced suppression of the percentage of IL-17+ cells in the I/I genotype culture, as shown in the top row of Figure 3A,...

Ngày tải lên: 12/08/2014, 15:22

... regulated by a set of physiological and biological factors, some of which are listed here, whereas survival of newly produced neurons is controlled by a separate group of factors Several genetic loci ... [8] This study [5] sheds some light on the complexity of the genetic control of neurogenesis in the adult brain, but it leaves the elucidation of exactly how the identified genes contribute to neurogenesis ... progress in understanding how genetic variation might control dentate gyrus neurogenesis, it is important to consider the available information on the genetic control of neural precursor proliferation...

Ngày tải lên: 14/08/2014, 16:21

... help with proof-reading of the drafts of this thesis i Table of Contents Acknowledgements Page i Table of Contents ii-v Summary vi-vii List of Tables viii List of Figures ix-x List of Abbreviations ... GENETIC CONTROL OF VERTEBRATE MUSCLE CELL IDENTITY LIEW HOE PENG B.Sc (Hons), M.Sc (Env Engg.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY INSTITUTE OF MOLECULAR AND ... establishment of the body axes, formation of the three germ layers through gastrulation and the differentiation of all the cell types required to form the tissues and organs of the adult animal One of the...

Ngày tải lên: 14/09/2015, 14:03

... GENETIC CONTROL OF VIRULENCE IN ERWINIA CHRYSANTHEMI PV ZEAE MUMTAZ BEGUM BINTE MOHAMED HUSSAIN (B.Sc Hons.) (UNIVERSITY OF LEEDS) A THESIS SUBMITTED FOR THE DEGREE OF MASTERS OF SCIENCE ... Acknowledgement ii Table of Contents iii Summary ix List of Tables xii List of Figures xiii List of Symbols xvi Chapter General introduction 1.1 Taxonomy of E chrysanthemi 1.2 The host range of E chrysanthemi ... Generation of mutants of EC1 defective in AHL signalling 22 2.3 Generation of avirulent mutants of EC1 26 2.4 Southern blotting and hybridization 26 iii 2.5 Sequence analysis of tox- mutants of EC1...

Ngày tải lên: 07/10/2015, 10:02

... and hypertrophy (i.e an expansion of adipocyte volume as a result of the accumulation of lipids) Consequently, knowledge of the origin and molecular control of adipocyte progenitor commitment ... complete loss of body fat, are highly prone to developing insulin resistance and associated diseases There is a dearth of knowledge concerning the genetics and associated molecular mechanisms giving ... important for our understanding of what controls the expansion of fat mass in different individuals Moreover, it is also important to understand the origins of each of the different white and brown...

Ngày tải lên: 29/03/2014, 22:21

... organization of the loci of polygenic resistance to late blight in terms of number of QTLs and lengths of confidence intervals By reducing the number of resistance loci by a factor of six (from 144 QTLs ... level of conservation of the marker order, and thus, of genomic sequences all over the genome This stresses the very close genetic relationships of those genetic backgrounds and gives evidence of ... analysis of the genetic factors controlling a trait across genomes of different related species and even of different genera of a plant family can be very powerful to perform a map-based dissection of...

Ngày tải lên: 11/08/2014, 11:21

... to each of these diseases is currently recognised as an important mode of infection control The obligate outbreeding reproductive habit of perennial ryegrass [10] leads to high levels of genetic ... xlpcat-561cg xlpffta.1 Figure Genetic linkage maps of LGs 1–4 from the NA6 parental genotype of the F1(NA6 × AU6) cross Genetic linkage maps of LGs 1–4 from the NA6 parental genotype of the F1(NA6 × AU6) ... xlpthc.2 xlpmads4.2 Figure Genetic linkage maps of LGs 5–7 from the NA6 parental genotype of the F1(NA6 × AU6) cross Genetic linkage maps of LGs 5–7 from the NA6 parental genotype of the F1(NA6 × AU6)...

Ngày tải lên: 12/08/2014, 03:20

... predictive of loss of LTNP status and/or disease progression in of 8, and differentiated slow progressors from elite LTNP who retained potent virological control Sustained immunological suppression of ... frequency of nonprogression in this TAHIV cohort after 20 years of infection [7] Early studies on this cohort of TAHIV patients led to the identification of the Sydney Blood Bank Cohort (SBBC) of long-term ... analyses of the SBBC may support this suggestion [13,17] However, death from other causes has prevented the establishment of definitive proof of disease progression in some individ- Page of 14 (page...

Ngày tải lên: 13/08/2014, 05:21

... production prevails The potential dichotomy of mechanisms governing translation initiation of retroviruses is a topic of some controversy The use of cap-independent initiation at an internal ... replication [76] A recent study of the 5' UTR of 16 env RNA isoforms produced by alternative splicing identified that production of Vpu is largely dependent on inclusion of exons that exclude the upstream ... efficiency of heterologous reporter mRNAs, and the introduction of point mutations that reduce the free energy of TAR restores translation of a TAR-CAT reporter RNA in vitro [17,156] Addition of TRBP1...

Ngày tải lên: 13/08/2014, 05:21

... letnica from Albanian waters of Lake Ohrid The main objective of this study was to determine the genetic architecture of Albanian trout from analysis of the mitochondrial DNA control region (mtDNA CR), ... composed of a genetic mosaic of haplotypes, related to most of the other trout lineages of the Mediterranean area analysed and reported in other studies However, due to a complexity of past migrations, ... limit of the range of S farioides, and close to the type location of Prizren, which shares the same water shed Thus, the results from this study support the congruence of the distribution of the...

Ngày tải lên: 14/08/2014, 13:21

... or because of the particular genetic background of some inbred lines used intensively for the study of the fate of RSV tumors [10, 33, 39] Naturally, most of the studies on RSV tumor control consider ... allowing the analysis of underlying mechanisms and the search for new genetic markers of disease resistance traits Such tools are particularly developed in the chicken for the analysis of immunoresponsiveness ... involved in the control of tumor regression or progression This was in some cases because of the easiness to select for the trait or because of the observation of the segregation of different phenotypes...

Ngày tải lên: 14/08/2014, 13:22