generalist in the short term or long term

... sensitivity of tumor cells to chemotherapy and radiotherapy by increasing the threshold for cell death induction [7] Therefore, the survival kinase Akt attracted major attention for the development ... cytarabine, idarubicine or etoposide, or with ionizing radiation, respectively [10,23] Therefore, in a final set of in vitro experiments, we analyzed whether treatment with the Akt-inhibitor ErPC3 ... Mcl-1 The rather low levels of Bcl-2 in the PC3 cells may explain why the radiation-induced down-modulation of Bcl-2 was of minor importance for the response of PC3-cells to radiotherapy and the...

Ngày tải lên: 09/08/2014, 09:20

... Youths with a clinically significant abnormal screening laboratory Youths who were actively suicidal, or if in the investigator's judgment participation in the study could place the youth at undue ... child with superior functioning) Safety assessments Substance use monitoring In order to monitor for substance use, urine toxicology screens were obtained at the screening visit, baseline visit, and ... of the following DSM-IV defined disorders: bipolar I or II disorder, psychotic disorder (history), obsessive-compulsive disorder (current), panic disorder (current), bulimia (current), or anorexia...

Ngày tải lên: 13/08/2014, 18:21

... showing Oxford scores against Postoperative Xray scores ‘Oxford Knee Scoring’ system Having said this although we were disappointed with our average Oxford core of 33, the average Oxford score ... component malpositioning and poor oxford scores This is in keeping Figure Plot of Oxford scores against the presence of medial knee pain in each patient with very recent work by the Oxford group who ... ignoring the presence of patellofemoral arthritis (if not clinically symptomatic) as suggested in the new guidelines by the Oxford group The vast majority of those patients in our study reporting...

Ngày tải lên: 20/06/2014, 07:20

... in the accuracy of distance estimations Therefore, for intermediate inbreeding values, the accuracy of distance estimations mainly depends on the number and on the degree of polymorphism of the ... within a breed) In order to infer the true history of populations, it is necessary to root the tree using an outgroup This work points out that, under the drift assumption, the major part of the ... yi ã As in Nei and Chakravarty [50], we not take into account the second and third terms of the Taylor expansion (in order to compute the second term we need to know the moment of the order of...

Ngày tải lên: 14/08/2014, 13:21

... brothers One (5)……… them is deaf.She is fond…(6)……watching cartoons which were made (7) Desney She goes to school (8)… the morning but(9) …Sartuday morning she doesn’t She always goes to school (10) ... doing ? ……………………………………………………………………………… 3.How does she go to school ? …………………………………………………………………………… V Rewrite the sentences with the same meaning 1.My brother is both clever and handsome My brother ... then answer the questions Maria lives (1)…a small town(2)… her grandmother.Everyday she gets (3)… early She is a good student She studies (4)……a big school.She has three brothers One (5)……… them...

Ngày tải lên: 21/04/2015, 09:00

... (patients and in Table 2) had clinical abnorof the intraventricular hemorrhage and included malities during the first days of life In infants one or more of the following: vomiting, seizures, in whom ... 16 infants appeared nor- hemorrhage originated from residual germinal mamal Of the infants in whom intraventricular trix in infants, and most probably originated from hemorrhage developed before ... posturing or abnormalities in Table The of the 12 infants of in hemorrhage/intraven- tricular hemorrhage as well as additional infants described previously in the literature are summahad rized in...

Ngày tải lên: 31/08/2015, 13:09

... 2.3.1 Elaboration In elaboration, the secondary clause gives more information to the information in the initial clause According to Halliday, (1994: 225) the secondary clause ‘does not introduce ... of the message, and the Rheme is the part in which the Theme is developed According to Eggins (1994: 275) the Theme typically contains familiar, or given, information, i.e information which has ... conjunction in the whole text; this can be explained by the fact that there is no need for it, as the story describes the thought of an old man waiting for his death in the same place in a clearing Finally,...

Ngày tải lên: 29/01/2014, 14:44

... 15 He led the way along a broad passage or corridor, with large paintings—for so they seemed to me—with a heavy curtain between each “These are very fine paintings,” I remarked, admiring a large ... than the last, that narrow-minded rivalry or jealousy seems to be ingrained in the sex, and though they improve in other respects, in that respect they get worse; it seems to get intensified as the ... appearance, as I have said, they were the same as we used in ’92; but though innocent enough to look at, they had more work in them than even the heads of the clubs In the centre of the ball was a small...

Ngày tải lên: 17/02/2014, 15:20

... tumor cell transduction is achieved with adenoviruses with RGD moieties in the HI loop of the fiber or in the KKTK domain of the fiber [30] Furthermore, mutation of the KKTK domain ablated binding ... mutation in the KKTK domain (AdTLGR) may reduce the potency of tumor targeting by the RGD modification in the HIloop [27] However, in contrast to earlier findings showing a decreased tumor cell ... needed in each group since individual tumors inside body cavity can be followed MRI allows also the use of non-subcutaneous tumor models for tumor growth follow-up Tumors grown in the correct organ...

Ngày tải lên: 18/06/2014, 16:20

... VEGF, suggesting a possible role for VEGF in the vascular heterogeneity of IPF [63] The question according to these findings is whether the increase in vascular density observed in the least fibrotic ... detected in the developing lung, suggesting that VEGF plays a central role in the formation of lung vasculature and also in the epithelial-endothelial interactions that are critical for normal lung ... In BAL fluid, VEGF levels actually correspond to VEGF levels of the epithelial lining fluid To estimate VEGF concentrations in epithelial lining fluid, investigators have taken into account the...

Ngày tải lên: 12/08/2014, 16:20

... technology, information technologists and medical engineers must determine the impact on existing hospital network infrastructure and medical devices There are those that argue that the intangible ... and Lapinsky Regardless of the potential risks, wireless technology is becoming increasingly prevalent in the critical care environment Hospitals are routinely using wireless solutions for patient ... monitoring, data collection, and enhanced communication Several companies are now offering wireless solutions for electronic-ICU applications, using either their own proprietary networks, or ‘piggybacking’...

Ngày tải lên: 13/08/2014, 08:20

... as the story develops Therefore, it is a must to analyse the title of the story The title of the story is Christina Rosenthal, searching for the meaning, Rosenthal is a Jewish name originating ... Nevertheless, the name Christina originates from Christian, a feminine form of 'Christian' from which the meaning and origin of the girl's name is derived The ideological intent of the story is ... reconciliation, intolerance, short- sightedness The combination among these words can create a rhetorical effect, making the impression of the rabbi's having regretful feeling As for the rabbi's feeling sorry...

Ngày tải lên: 02/03/2015, 14:22

... the flow of interpersonal and ideational meanings as they unfold in a text The textual meta-function reflects the meanings according to the choices for placing the information in the sentences, ... about the lives of the common people there The Last Leaf” is one of the most famous short stories of O‟Henry, appearing in the New York World Sunday Magazine The targeted readers, therefore, ... anaphoric anaphoric anaphoric 96-74-73-72 98-92-52-46-31-30-27 100-98-92-52-46-31- The (window) The (window) There The (brick wall) its The (vine) its they them The (doctor) such That (vine) The...

Ngày tải lên: 02/03/2015, 14:25

... as or (rather), in other words, that is to say, or in writing, i.e In the following example, “That clock doesn‟t go; it‟s not working‖, the second clause restates the meaning of the first one in ... was the absence of Flora, the little white goat who kept the horses company in the barn and in the fields||| The defining relative clause ―who kept the horses company in the barn and in the fields” ... study does not lie in the theoretical findings but on the basis of these it is to enlighten the analysis of the chosen story to understand the way the author constructs the text in terms of expansion...

Ngày tải lên: 10/07/2015, 14:23

... Mother was making a cake The girl was painting a picture Answers A poem was being written by Megha Clothes were being washed by the woman The house was being built by the masons A cake was being ... by mother A picture was being painted by the girl Be first to know when grammar rules change! Sign up to our newsletter here: englishgrammar.org (It's free) Powered by TCPDF (www.tcpdf.org) ...

Ngày tải lên: 11/07/2015, 10:18

... in mine in 34; in my garden in 35; forth in 49; in the market place in 49; in their gallery in 52; upon their stringed instruments in 54; round her in 58; down in 62; on the grass in 62; in his ... through the reeds of the river in 284; to the sea in 285; in the long grass in 290; in her heart in 290; at noon in 291; out in 292; to the Professor’s house in 302; in his hand in 302; in the doorway ... brow in 25; in my arm in 32; in the market place in 49; in their gallery in 52; on the grass in 62; in his hands in 63; in the air in 67; after a sunbeam in 69; in the oak-tree in 77, etc They...

Ngày tải lên: 14/07/2015, 11:53

... to these nouns However, when pointing forward in the text, readers can gain more information of these words All information stated afterward helps modify for the previous nouns, for instance, the ... article "the" in the story 23 The total number of the article "the" in the story is 709 ties, in which, "the" used as anaphoric reference takes up 424 ties, accounting for 60%; cataphoric reference ... that the main character of the story is a man Furthermore, the low frequency of occurrence of the first and the second their person prove that there are no or few dialogues in the story In contrast,...

Ngày tải lên: 15/07/2015, 12:57

... of the short story The Last Leaf” by O’Henry who is famous for short stories and their unexpected endings with the hope of exploring how the writer develop the text and what the purpose is Cohesive ... Cohesive Ties in the short story The Last Leaf” by O’Henry” as the title of my MA Thesis, using Halliday’s functional grammar as a theoretical framework 1.2 Aims of the Study The aim of this ... concepts for the study: linguistic system, metafunctions and cohesion in chapter two In chapter three, I will analyze the themerheme patterns and the main cohesive ties in the story 1.3 Scope of the...

Ngày tải lên: 10/08/2015, 19:48