... activity by assessing the requirements for restoration of the activity of the mutant Results The intracellular localization of Rev and mutants The intracellular distribution of the M4 and the M4 derived ... shown instate panels to the left (panels a-e) The intracellular steady state localization of the wild type Rev and mutants is shown in the panels to the left (panels a-e) The panels to the rights ... detection of Rev and the M4 mutants There was no significant difference in activity of wild type Rev or the NOS-M4 and M4-M4 mutants whether the reporter contained RRE or six IIB high affinity binding...
Ngày tải lên: 13/08/2014, 09:21
... chain management in the presence of EMs because this study investigates inventory control problems in the presence of an EM 2.1.1 E-Business and supply chain management Geoffrion and Krishnan ... and there are almost infinite participants in EMs, a company can always find supply and demand information in an EM to carry out spot shop - 29 - Chapter An inventory system in the presence of ... challenging problems Swaminathan and Tayur (2003) pointed out that companies should understand the advantages of their current supply chains and new channels so that they can manage the material and...
Ngày tải lên: 16/09/2015, 15:53
THE ACOUSTOMAGNETOELECTRIC CURRENT OF a RECT ANGULAR QUANTUM WIRE WITH AN INFINITE POTENTIAL IN THE PRESENCE OF AN EXTERNAL MAGNETIC FIELD
... understand the properties of quantum wire material We have obtained the AME current I in the RQW with an infinite potential in the presence of an external magnetic field The dependence of the expression ... have analytically investigated the possibility of the AME effect in the RQW with an infinite potential We have obtained analytically expressions for the AME effect in the RQW with an infinite ... electrons, the temperature and the cross-sectional area of the RQW The curve of the AME current I strongly increases when the low temperature and the large value range of the acoustic wave number qz The...
Ngày tải lên: 30/10/2015, 20:58
Báo cáo sinh học: " The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon" doc
... than the poliovirus IRES Including the extension into the coding region into the SD-1 IRES resulted in 1.5–3 fold increase in translational efficiencies irrespective whether the cell line is of ... in which the mutation was introduced (Fig 6) In mutant M7 disrupting base changes of mutant M6 were repaired by introducing complementary bases in the opposite strand (Fig 6) Interestingly, the ... mutational analysis of stem and stem of the putative pseudoknot indicate the relevance of this region of tertiary structure for BVDV translation Strength of the BVDV strain SD-1 IRES in cell lines of...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " The internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codon" ppt
... than the poliovirus IRES Including the extension into the coding region into the SD-1 IRES resulted in 1.5–3 fold increase in translational efficiencies irrespective whether the cell line is of ... in which the mutation was introduced (Fig 6) In mutant M7 disrupting base changes of mutant M6 were repaired by introducing complementary bases in the opposite strand (Fig 6) Interestingly, the ... mutational analysis of stem and stem of the putative pseudoknot indicate the relevance of this region of tertiary structure for BVDV translation Strength of the BVDV strain SD-1 IRES in cell lines of...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học: " Topological confinement in an antisymmetric potential in bilayer graphene in the presence of a magnetic field" pptx
... oscillator strength for the ® transition In contrast to the single kink profile the shift in the intragap energies of the kink-antikink potential leads to a non-zero value for the oscillator strength ... as function of (a,c) the y-component of the wavelength ky = ky l and (b,d) the external magnetic field B0 The inset in (a) shows the wavespinors for kyl = proximity of an antikink induces a strong ... zero and non-zero magnetic field The insets in panels (a),(b) show the wavespinors of the levels (1) and (3) corresponding to the points with zero oscillator strength arises due to the coupling of...
Ngày tải lên: 21/06/2014, 02:20
ON THE HALL EFFECT IN PARABOLIC QUANTUM WELLS WITH AN IN PLANE MAGNETIC FIELD IN THE PRESENCE OF a STRONG ELECTROMAGNETIC WAVE (LASER RADIATION)
... using Hamiltonian (4) and the procedures as in the works [9-14], we obtain the quantum kinetic equation for electrons in the single (constant) scattering time approximation Then utilizing the ... of the Hall conductivity as well as the HC The influence of EMW is interpreted by the dependence of the Hall conductivity and the HC on the amplitude E0 and the frequency Ω of the EMW besides the ... well as the Hall coefficient utilizing the quantum kinetic equation method in the presence of a strong EMW II.2 Expressions for the Hall conductivity and the Hall coefficient In the presence of a...
Ngày tải lên: 31/10/2015, 10:41
Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
... in the presence of 100 lM MPTP (B), in the presence of 200 lM MPTP (C), in the presence of 100 lM MPP+ (D), in the presence of 200 lM MPP+ (E), in the presence of 100 lM MPTP and 50 lM dopamine ... solid line), in the presence of 100 lM neurotoxin ( , dotted line), in the presence of 200 lM neurotoxin ( , dotted line) and in the presence of neurotoxin and 50 lM dopamine (h, dashed line) • 1692 ... (F), in the presence of 200 lM MPTP and 50 lM dopamine (G), in the presence of 100 lM MPP+ and 50 lM dopamine (H) and in the presence of 200 lM MPP+ and 50 lM dopamine (I) Discussion MPTP infusion...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Bond Market Structure in the Presence of Marked Point Processes doc
... self-financing portfolio if and only if certain integral equations of the first kind (the “hedging equations”) have solutions Furthermore, the integral operators appearing in these equations (the ... of counting processes (Jarrow–Madan also consider the interplay between the stock- and the bond market) In the present paper we focus primarily on the case of an in nite mark space, but the interest ... apply part of the present theorem We now turn to the issue of so called “martingale modelling”, and remark that one of the main morals of the martingale approach to arbitragefree pricing of derivative...
Ngày tải lên: 16/02/2014, 02:20
Tài liệu Báo cáo khoa học: NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles doc
... respectively retained in the centre of the interhelical linker and at the C-terminus of micelle-associated VpUcyt Position of VpUcyt relative to the micelle NMR signal intensities of individual VpUcyt ... iterative manner The input of the first cycle consisted of the 3D NOESY data, the amino acid sequence of VpUcyt and the chemical shift list reflecting the sequence-specific resonance assignment Intermediate ... chains of the Ser53 and Ser57 in the interhelical linker, forming a highly conserved phosphorylation motif, are visualized in ball-and-stick format In contrast to the well-defined helices and the...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt
... generation in the course of the continuously monitored reactions were analysed as described in the Materials and methods For the reactions in the absence of fatty acids, or in the presence of oleate and ... (triangles) A Fig Kinetic parameters of plasmin in the presence of fatty acids The values of kp and Km were determined from the amidolytic assay of plasmin activity, according to Model I, in the ... resulted in a decrease, of up to two-fold, in the kp of plasmin Considering the recently described reversible nature of the plasmin inhibition by oleic acid [3] and the changes of the kinetic parameters...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc
... activity of the reaction intermediate, FVaint This facilitated the determination of loss of FVa cofactor activity during the initial stage of inactivation and minimized the in uence of the k306 ... heparin inhibits cleavage at Arg506 and stimulates initial cleavage at Arg306, inactivation of Fig Kinetic analysis of the inactivation of FVa by APC in the presence and absence of heparin Initial ... heparin binding To verify that the inhibition of APC-mediated FVa inactivation by heparin is related to the ability of heparin to bind APC, we used recombinant mutants of APC harboring mutations in...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine pptx
... proton transfer, in the transition state, via the catalytic histidine The concerted proton transfer would be between the serine and the leaving group and later between the water and the serine Cyclic ... substrate, of the human BuChE mutant E197Q The solid circles indicate the measured kcat values, the solid squares indicate the measured bkcat values, and the lines are the result of fitting the measured ... use the histidine to shuttle protons: first, between the serine and the leaving group; and then between the attacking water and the serine In its role as a proton shuttle, the catalytic histidine...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt
... [21–25], and DGD° values in the presence of these osmolytes are given in Table However, DGD° values of RNase-A in the presence of alanine, serine, lysine, b-alanine, taurine and dimethylglycine have ... efficiency in the presence of this group of osmolytes Interestingly, there is a linear relationship between DDGD° and Dlog(kcat ⁄ Km) in the presence of methylamines and sugar However, the slopes of the ... different In fact, the slope in the presence of sugar osmolytes is 10 times less than that in the presence of methylamines A higher slope in the case of methylamines will mean that the total...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc
... biosynthesis of androstadienol in humans (A) and pigs (B) does not require prior formation of 17a-OH-preg and DHEA The lack of androstadienol synthesis in the presence of lM of ketoconazole (C), an inhibitor ... P450c17 is involved in the biosynthesis of androstadienol Effect of cyt b5 on DHEA and androstadienol biosynthesis In order to determine the effect of cyt b5 in P450c17 16-ene-synthase and 17a-hydroxylase/17,20-lyase ... pick them up On the other hand, the orphan receptor ligands are most probably produced locally in the various tissues Because of the small volume of the cell, the production of a little amount of...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNase pptx
... structural analysis of an analog of an intermediate formed in the ratedetermining step of one pathway in the oxidative folding of bovine pancreatic ribonuclease A: automated analysis of 1H, 13C, and ... of the interchain disulfide bridges in the recombinant sample [11] The kinetics of the N-terminal arms swapping in the P19A-BSRNase is comparable to that of BS-RNase (Fig 5B) Interestingly, the ... NMR, CD and differential scanning microcalorimetry, and an investigation of the kinetics of swapping of all variant dimers in comparison with that of the parent protein mutations are underlined)...
Ngày tải lên: 16/03/2014, 23:20
large-scale hydrothermal synthesis of wo3 nanowires in the presence of k2so4
... of KNO3 With an increase in the content of KNO3, the dimension of nanoparticles only became smaller Similarly, the nanorods and nanoparticles were obtained in the products with the addition of ... is also an important factor influencing the crystallization process and the growth of the WO3 nanowires With the addition of different inorganic salts, the compositions and the corresponding properties ... pressure, and composition of the solution [21] The formations of nanowires first need the anisotropy during the growth process for the nanoparticles In our experiments, the presence of the salts...
Ngày tải lên: 20/03/2014, 13:04
WORMS: IDENTIFYING IMPACTS ON EDUCATION AND HEALTH IN THE PRESENCE OF TREATMENT EXTERNALITIES ppt
... These results are largely robust to including the proportion of Group pupils in the surrounding area as the explanatory variable, rather than the total number of Group pupils in the surrounding ... deworming, why a large minority of children did not take the free deworming drugs, and the role of drug cost, social learning, and other behavioral factors in influencing take-up of deworming drugs ... it is worth noting that Thein-Hlaing, Thane-Toe, Than-Saw, Myat-Lay-Kyin, and Myint-Lwin’s (1991) study in Myanmar finds large height gains among treated children within six months of treatment...
Ngày tải lên: 22/03/2014, 15:20
Báo cáo khoa học: Kinetic analysis of zymogen autoactivation in the presence of a reversible inhibitor pptx
... is quantitative, the increase in trypsin activity shows the appearance of newly processed trypsin during the reaction, and the y scale (ordinate) in Fig can then be expressed as the amount of active ... autoactivation in the presence of 100 lM p-amindinobenzamidine As seen in this figure, the presence of p-amindinobenzamidine lengthened the lag time considerably Similarly, the values of à à Km , kcat and ... indicating that the dominant effect of the Ca2+ concentration appears Fig Autocatalytic activation of trypsinogen by trypsin in the absence or presence of p-amindinobenzamidine (A) Effect of trypsinogen...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: "What’s There to Talk About? A Multi-Modal Model of Referring Behavior in the Presence of Shared Visual Information" potx
... theoretical understanding of human referring behavior in the presence of shared visual information They suggest that shared visual information of the task objects and surrounding workspace can ... understanding of how humans make use of various forms of shared visual information in their everyday communication The development of an integrated multi-modal model of referring behavior can improve ... in the left hand panel The advantage of this setup is that it allows exploration of a number of different arrangements of the shared visual space For instance, we have varied the proportion of...
Ngày tải lên: 24/03/2014, 03:20