further characterization of p450pyr and related mutants
Engineering soluble microenvironments in microfluidic systems
Ngày tải lên :
12/09/2015, 10:22
... stirring rate of (A) 700 rpm and (B) 1000 rpm Figure 16 controlled-release property of the GMs with a cross-linking density of (A) 5% and (B) 10% FITC-dextran of 9.5 kDa, 70 kDa and 150 kDa are ... activity, and (D) adiponection secretion for C3A, A549, HK-2 and HPA, respectively At 50-1000 ng/ml of EGF, the functions of C3A and A549 cells were stimulated by more than fold, and that of HPA ... function of C3A cells were inhibited by ~45%, that of A549 and HPA were stimulated by ~1.5 fold, and that of HK-2 were little affected (slight inhibitory effect of ~10%) Data are the mean ± s.e.m of...
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Overcoming mass transfer barriers in sandwich configuration for primary hepatocytes culture
Ngày tải lên :
27/11/2015, 12:39
... determinants of drug disposition Therefore, it is not surprising that characterization of the hepatic transport and biliary excretion properties of potential drug candidates is an important part of the ... secretion of toxins out of cell 13 body via several of transporters inside and formation of bile canaliculi outside With high excretory function and polarity re-establishing, we hypothesis that sandwich ... exchange of nutrients, products, and chemical signals with the bulk of the medium The two layers of support divide the sandwich culture assembly into two environments, the extra-sandwich and the...
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A STUDY ON techniques to teach english vocabulary for primary schools in quang ninh
Ngày tải lên :
11/12/2013, 23:53
... know and be able to use grammar of the language target, they are also hoped to familiar with collocation and understand the connotation meaning of the words This type is often used in speaking and ... province and found their reality The focus of survey questionnaires depended on the characteristics of teachers and students and the teaching and learning condition in these schools, and on the ... interest and involvements in lessons 3.Scope of the study In fact, there are lots of various techniques to teach English vocabulary for primary students It requires much of time and effort Furthermore,...
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The National Curriculum Handbook for primary teachers in England doc
Ngày tải lên :
02/04/2014, 05:20
... permission of the Controller of HMSO The additional information is copyright of the Qualifications and Curriculum Authority By agreement between the Controller of HMSO and QCA reproduction of any of ... distinguishing between right and wrong It should develop their knowledge, understanding and appreciation of their own and different beliefs and cultures, and how these influence individuals and societies The ... rights of being members of families and communities (local, national and global), and an ability to relate to others and to work with others for the common good They display a sense of belonging and...
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Tài liệu Evidence-Based Guidelines for Migraine Headache in the Primary Care Setting: Pharmacological Management of Acute Attacks doc
Ngày tải lên :
21/02/2014, 12:20
... frequency and severity of attacks, the presence and degree of temporary disability, and the profile of associated symptoms such as nausea and vomiting The patient’s history of, response to, and tolerance ... placebo-controlled study each for diclofenac-K,60 flurbiprofen,61 naproxen,62 piroxicam SL,63 pirprofen*,29 and proquazone*.64 Diclofenac sodium IM* was superior to placebo65 and low doses of acetaminophen IM*.66 ... C, Björkman R Diclofenac-K (50 and 100 mg) and placebo in the acute treatment of migraine Cephalalgia 1993;13(2):117-123 61 Awidi AS Efficacy of flurbiprofen in the treatment of acute migraine...
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Effective techniques to teach English for 1st graders at Vo Thi Sau primary school in Hai Phong city.
Ngày tải lên :
19/03/2014, 17:07
... beginning of sentence In English, we often use “please” to express the aims of request After studying, we see that command is used quite great in four kinds of sentence The percentage of command ranks ... the percentage of statement) Through chart No 3, it indicates that the percentage of Group is more than that of Group and command is used more than question and exclamation Command occupies from ... details of personal pronoun in the salutation of letters and in the body of letters: 2.1 The system of personal pronoun in the salutation: 2.1.1 The system of personal pronoun in the salutation of...
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Attitudes, barriers and facilitators for health promotion in the elderly in primary care doc
Ngày tải lên :
22/03/2014, 14:20
... the lack of time in daily practice, insufficient reimbursement of preventive and health promotion advice and scepticism about the effectiveness of health promotion in the elderly Lack of time, ... aspects of health promotion in the elderly B Financial aspects of health promotion in the elderly C Accessibility and target population D Role of GPs in health promotion in the elderly E Fields of ... demographic shift with an increase of chronic conditions and multimorbidity has increased the “tyranny of the urgent”, worsened by an increasing shortage of GPs in Switzerland [18] As another important...
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Báo cáo khoa học: Differential expression of liver and kidney proteins in a mouse model for primary hyperoxaluria type I pdf
Ngày tải lên :
23/03/2014, 03:20
... peroxisomal (FP) and cytosolic (FC) fractions Densitometry of western blot bands was performed and units of selected proteins were calculated A representative western blot band for each protein of each ... bisphosphatase and catalase, whereas liver enolase and carbonic anhydrase were downregulated Comparable amounts of b-actin were present in AgxtKO and wild-type cytosolic fractions, and the absence of AGT1 ... lg of total protein were applied to the basic end of the tube gel Cathodic and anodic buffers were 20 mm NaOH and 8.7 mm H3PO4, respectively Isoelectric focusing steps consisted of h at 100 and...
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Báo cáo khoa học: Novel b-1,3-, 1,6-oligoglucan elicitor from Alternaria alternata 102 for defense responses in tobacco docx
Ngày tải lên :
23/03/2014, 11:20
... concentration of 20 lgÆlL)1 was used The elicitor and DHBA solutions were mixed : (v ⁄v), and then a ⁄10 volume of 0.1% NaCl was added to the solution A 1.0-lL quantity of the solution of matrix and analyte ... the expression of known defense -related genes, which are typical of three different defense pathways: acidic and basic PR3 encoding chitinase enzymes of the PR protein family, PAL and CCoAOMT from ... (Table 2) and five serial dilutions of each first strand cDNA PCRs were performed through 25 cycles and resulted in amplification linearly related to RNA amounts The PCR mixture contained 0.4 lm of each...
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A study on techniques to improve English vocabulary for 3th graders at Quang Trung primary school in Hai Phong
Ngày tải lên :
26/03/2014, 00:16
... production of a phoneme can lead to misunderstanding This can be very frustrating for learner who may have a good command of grammar and lexis but have difficulty in understanding and being understood ... the writing of a word or words with the necessary letters and diacritics present in an accepted standard order It is one of the elements of orthography and a prescriptive element of alphabetic ... students of 3th graders According to data of above pie chart, main difficulties of teachers is lacking of workable teaching techniques and teaching condition Pictures and audiovisual aids are often...
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Báo cáo hóa học: " Mutation or loss of Wilms’ tumor gene 1 (WT1) are not major reasons for immune escape in patients with AML receiving WT1 peptide vaccination" ppt
Ngày tải lên :
18/06/2014, 16:20
... conception and design, acquisition of data, analysis and interpretation of data and wrote the manuscript; AL, AN and OS have made substantial contributions to acquisition of data, analysis and interpretation ... Dickinson) and data were analyzed using CellQuest software Results and Discussion Ten HLA-A2 positive patients with AML were analysed for mRNA expression levels of WT1 and for mutations of the WT1 ... loss of the HLA-A2 allele, we analyzed HLA-A2 expression on leukemic blasts of patients In all patients more than 90% of blasts stained positive for HLA-A2 In none of the patients a difference of...
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Báo cáo hóa học: " Research Article Three Novell Analog-Domain Algorithms for Motion Detection in Video Surveillance Arnaud Verdant,1 Patrick Villard,1 Antoine Dupret,2 and Herv´ Mathias3 e" pdf
Ngày tải lên :
21/06/2014, 07:20
... regard to noise and impact of parasitic capacitances A and B may be up to 1024 The so-formed matrix is bordered on one side by a vector of A switched capacitor analog processors A column of multiplexers ... algorithm Sn is the pixel gray level value and Mn the background estimation, and Vn the threshold of Δn Table 1: Motion detection performance of two state -of- the-art algorithms Grey level sequence ... computational resources of CIS architectures, thus eliminating true Markovian approaches Our idea is to get rid of constants related to the background of the scene The detection of grey level variations...
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Báo cáo hóa học: " Research Article Nonlinear Synchronization for Automatic Learning of 3D Pose Variability in Human Motion Sequences M. Mozerov, I" pot
Ngày tải lên :
21/06/2014, 19:20
... limb, and therefore we require a unique segment per each Hence, we compute the position of joints and (hip and neck joints) as the mean between the previously computed joints and 3, and and 9, ... mean performance, and σt and vt correspond to the computed standard deviation and mean direction of motion at each time step t, respectively Finally, to handle the cyclic nature of the waking action, ... representation of human motion which relates the precision of the model with its complexity in a natural way and makes it suitable for different kinds of applications which demand more or less...
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Báo cáo hóa học: " Research Article Adaptive Probabilistic Tracking Embedded in Smart Cameras for Distributed Surveillance in a 3D Model" doc
Ngày tải lên :
22/06/2014, 22:20
... model of the environment of interest, an easy plug “n” play style of adding new smart camera nodes to the network, the distributed tracking and person handover itself, and the integration of all ... implementation, as it can only handle unimodal pdfs and linear systems Also extended Kalman filters are not capable of handling multiple hypothises and are thus not that robust in cases of occlusions It became ... output of traditional cameras are used as live textures mapped onto the ground/walls of a 3D model However, the idea of a surveillance system consisting of a distributed network of smart cameras and...
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Guide for Sound Insulation in Wood Frame Construction Part 1 pot
Ngày tải lên :
08/08/2014, 13:21
... Page of 103 Preamble and Acknowledgement This Guide addresses flanking transmission of sound through wood framed construction Continuous structural elements and connections at the junctions of ... all buildings and its importance in determining the apparent sound insulation (that perceived by the occupants) depends on of the construction details of the walls, the floors and their junctions ... derivative of four industry-sponsored research projects conducted at IRC/NRC The focus and construction details were decided by a Steering Committee of technical representatives from each of the...
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Báo cáo y học: "Sigma-1 receptor agonist fluvoxamine for postoperative delirium in older adults: report of three cases" docx
Ngày tải lên :
08/08/2014, 23:21
... delirium A further study of fluvoxamine alone will be necessary Delirium is theorised to be a neurobehavioural manifestation of imbalances in the synthesis, release, and inactivation of a number of neurotransmitters ... beneficial effects of fluvoxamine against the postoperative delirium of these patients In order to confirm the role of sigma-1 receptors in the treatment of postoperative delirium, a randomised double-blind, ... mechanisms of action, although a further study will be necessary Drug treatment for postoperative delirium requires careful consideration of the balance between the effective management of symptoms and...
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Báo cáo khoa học: "Human vascular adhesion proteın-1 (VAP-1): Serum levels for hepatocellular carcinoma in non-alcoholic and alcoholic fatty liver disease" pdf
Ngày tải lên :
09/08/2014, 03:22
... because the levels of these adhesion molecules change in different states, the determination of their concentrations can be beneficial for the diagnosis and treatment and monitoring of diseases [9,12,16,17] ... specificity of 100% The threshold level of VAP-1 for diagnosis of HCC is a 100 ng/mL [20] The concentrations of VAP-1 measured by ELISA in healthy person were found to be between 21 and 89 ng/mL ... Kusunoki M: Circulating form of human vascular adhesion protein-1 (VAP-1): decreased serum levels in progression of colorectal cancer and predictive marker of lymphatic and hepatic metastasis J Surg...
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Báo cáo khoa học: "SemiDecreased 3D observer variation with matched CT-MRI, for target delineation in Nasopharynx cancer" pdf
Ngày tải lên :
09/08/2014, 08:22
... design and implementation of big brother software enabling analysis of the data, PN: observer, design of the study, FPam: Radiologist, interpretation of anatomical location of variation, design of ... addition of PET to CT-based delineation particularly decreased observer variation at the interfaces towards mediastinum and hilum and in the case of atelectasis Furthermore, the use of sagittal ... opinions of the anatomical target extension rather then visibility of a structure Results A total number of 400 delineations were analyzed The tumor volumes and standard deviations of these volumes...
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Báo cáo khoa học: "High-dose rate brachytherapy (HDRB) for primary or recurrent cancer in the vagina" docx
Ngày tải lên :
09/08/2014, 09:22
... serous endometrial cancer and had partial regression of the tumor Of the 17 patients achieving a CR, had local recurrence and had systemic recurrence at a median time of months (range 6–22 months) ... significant narrowing and shortening of vagina (length of residual vagina was about cm) Both these patients had proximal vaginal disease and had prior radiation therapy and their EQ for total ... uniformity and ratios between tumor and normal tissue is important advantage of HDR brachytherapy These advantages of HDRB over LDRB have to be weighed against the need to use a larger number of HDR...
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Báo cáo y học: " Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience" pdf
Ngày tải lên :
09/08/2014, 10:21
... size of osteophytes, and significant improvement in clinical indicators of pain and disease activity A first randomized controlled trial in patients with knee OA demonstrated a good safety profile ... structural damage process of OA but also plays an important role in pain transmission Results from in vitro studies and animal models of OA support the dominant role of IL-1β early in the disease ... of IL-1ra (150 mg, the maximum tolerated dose) [8] We performed a multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical response, safety, and tolerability of...
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