functional and clinical implications
Báo cáo khoa học: Two novel Mesocestoides vogae fatty acid binding proteins – functional and evolutionary implications doc
... Caenorhabditis elegans and Manduca sexta FABPs are good examples [24] The observed high expression of MvFABPs at the tegumental level has interesting implications in platyhelminth biology and parasite ... mica, Facultad de Ciencias, UdelaR, Montevideo, Uruguay) and Dr I Noguera (Department of Cell Biology and Kaplan Cancer Center, and the Raymond and Beverly Sackler Foundation Laboratory, New York ... acidic forms (pI 5.5 and 5.9) with the same mass, and a heavier basic one (pI 7.7) (Fig 5C) As the reported sequences not contain N-terminal residues, comparisons between calculated and experimental...
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THE CARDIOVASCULAR SYSTEM – PHYSIOLOGY, DIAGNOSTICS AND CLINICAL IMPLICATIONS pot
... CARDIOVASCULAR SYSTEM – PHYSIOLOGY, DIAGNOSTICS AND CLINICAL IMPLICATIONS Edited by David C Gaze The Cardiovascular System – Physiology, Diagnostics and Clinical Implications Edited by David C Gaze Published ... Morphology and Functional Changes of Intestine, Trophology Status and Systemic Inflammation in Patients with Chronic Heart Failure 383 G.P Arutyunov and N.A Bylova Chapter 20 Evaluation and Treatment ... pathophysiology, clinical presentation and implications of cardiovascular diseases The first chapter of this section explores the relationship of cardiovascular health and exercise from both the European and...
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Chromosomal Instability and Aging Basic Science and Clinical Implications doc
... along the way: my parents, Kay and Toshi, my teachers, and my husband, Rusty And to Mr William T Comfort, Jr., and the John A Hartford Foundation, whose kindness and interest in this project were ... Chromosomal Instability and Aging Basic Science and Clinical Implications edited by Fuki M Hisama Sherman M Weissman Yule Universify School ... instability in human diseases and model organisms We intend this book for students, scientists, and physicians interested in the biology of aging and human genetics, and for those studying genomic...
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Báo cáo hóa học: " Ventilator-induced lung injury: historical perspectives and clinical implications" docx
... mL/kg and PEEP of cmH2O) only 36 h after randomization [62] However, this study was not designed to address whether these decreases were associated with improved clinical endpoints and the clinical ... lung injury; and 3) studies modulating hormonal and metabolic pathways: inhibition of the renin-angiotensin system [92,93] and pretreatment with atorvastatin or simvastatin [94,95] Clinical relevance ... Ventilator-induced lung injury: historical perspectives and clinical implications Annals of Intensive Care 2011 1:28 Submit your manuscript to a journal and benefit from: Convenient online submission Rigorous...
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THE CARDIOVASCULAR SYSTEM – PHYSIOLOGY, DIAGNOSTICS AND CLINICAL IMPLICATIONS pot
... Morphology and Functional Changes of Intestine, Trophology Status and Systemic Inflammation in Patients with Chronic Heart Failure 383 G.P Arutyunov and N.A Bylova Chapter 20 Evaluation and Treatment ... coordinated operation of the heart and the associated blood vessels Knowing their ratios and considering the actual anatomic and functional status of the heart and the blood vessels in every phase, ... outstanding person! She was the General Manager of the Company CARDIOCODE-Finland She remains in our memory for ever 22 The Cardiovascular System – Physiology, Diagnostics and Clinical Implications...
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Báo cáo y học: "The role and clinical implications of G6PI in experimental models of rheumatoid arthritis" pptx
... the TCR transgenic K/B×N model and the situation in patients Some of the major clinical and immunological similarities and differences between CIA, the K/B×N model and G6PI-induced arthritis are ... importantly, depletion of CD4+ cell on days 11 and 14 (i.e when clinical symptoms are at their maximum) induces rapid remission of arthritis both clinically and histologically [93] Thus, in G6PI-induced ... Kamradt and Schubert Figure Arthritis scores of () DBA/1 wild-type, (᭹) DBA/1 FcγR common γ-chain deficient, and (᭡) DBA/1 FcγRIIB deficient mice Data are presented as mean clinical scores ± standard...
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Báo cáo khoa học: "SemiIntensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications" pptx
... reports No 50 and 62[13] The GTV-T and GTVN were delineated using information from the diagnostic CT and the Endoscopic Ultrasound (EUS) The clinical target volume (CTV) included the GTV-T and GTV-N ... Tissue Avoidance Table and Figure summarize the mean D5 and V40 values for the bladder, SB, and rectum IMRT planning produced significantly lower D5 and V40 values for the bladder and the SB (p < 0.05) ... Carpenter for editorial assistance, and Arantxa Zubiria y Charo Irigoyen for technical contribution Authors’ contributions JA and MM: idea and concept LA and LIR: design and development of study LIR:...
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Báo cáo y học: "Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications" doc
... glucose ≥6.1 mmol/L aEuropeans, Sub-Saharan Africans, and Eastern Mediterranean and Middle East (Arab) populations; bSouth Asians and Ethnic South and Central Americans HDL, high-density lipoprotein ... membrane On the other hand, the MAP kinase pathway begins with phosphorylation of Shc, Grb2/Sos and ras and results in the activation of extracellular signal-regulated kinase (ERK)-1 and ERK-2 Activated ... populations are presented in Table Clinical significance In view of the controversy about the clinical criteria and the lack of a unifying pathophysiologic process, the clinical significance of MetS...
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Báo cáo y học: " Changes in health-related quality of life and clinical implications in Chinese patients with chronic cough" pot
... accurately analyzed, which is useful for assessment of cough severity and therapeutic efficacy, and can help to guide clinical practice and research in chronic cough Cough symptom score, generic instruments ... got a standard score of 0-100 [12] Among them, PF, RF, BP and GH make up the physiological domain, and these items derive the physical component summary (PCS) In contrast, RE, VT, MH and SF comprise ... correlation between LCQ and capsaicin cough threshold, which was similar to the results reported by Birring [6] and Chang [30] It may be due to the different implications of HRQOL and capsaicin cough...
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Báo cáo y học: "Clinical review: Sleep measurement in critical care patients: research and clinical implications" pdf
... practicality and a compromise between frequency and accuracy will be necessary No – extensive observation required of eyelid positioning, respiration, and eye and body motility and responses ... conceived the clinical study, enrolled patients, collated the data, analysed and interpreted results, and conceived and undertook the literature review CM completed the statistical analysis and contributed ... Results are presented as number and percentage, mean and standard deviation (SD), or median and interquartile range (IQR), as appropriate APACHE II, Acute Physiology and Chronic Health Evaluation...
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Báo cáo y học: "Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection" pptx
... [12], many unresolved questions remain regarding the exact virulence and clinical implications of drug-resistant viral mutants, and how to use this information to make treatment decisions This is ... the emergence of K65R viral mutants, (iii) what are the clinical implications of K65R mutants, and (iv) what is the role of CD8+ cells and continued tenofovir treatment in controlling viremia ... groups had similar viral RNA levels in plasma and infectious titers in PBMC, and a similar decline in absolute counts and percentages of CD4+ T lymphocytes and CD4+/CD8+ T cell ratios during the first...
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Báo cáo y học: "Bench-to-bedside review: Bacterial pneumonia with influenza - pathogenesis and clinical implications" pdf
... in pandemic influenza: implications for pandemic influenza preparedness J Infect Dis 2008, 198:962-970 Hers JF, Masurel N, Mulder J: Bacteriology and histopathology of the respiratory tract and ... Netherlands 3Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, PO Box 22700, 1100 DE, Amsterdam, The Netherlands Published: ... 37:186-196 Crusat M, de Jong MD: Neuraminidase inhibitors and their role in avian and pandemic influenza Antivir Ther 2007, 12:593-602 Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell...
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Unraveling genomic instability in multiple myeloma mechanisms, biological and clinical implications
... et al 2003c) found N-RAS and K-RAS mutations, respectively, in 17% and 6% of tumors, whereas Kuehl and Shaughnessy found N-RAS and K-RAS mutations, respectively, in 14% and 17% of tumors (personal ... the following specific aims: a) Describe the landscape and clinical relevance of genomic complexity using aCGH Rationale and Hypothesis Current understanding of MM genetics is hampered by inadequacies ... 1q gain (44% and 48% respectively) and 8p loss (27% and 28% respectively) had almost identical prevalence in both HRD and NHRD MM Figure 2.2 Penetrance plot of chromosome gains and losses by...
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coma science - clinical and ethical implications - s. laureys, et al., (elsevier, 2009)
... Research and the University, and University ` Hospital of Liege in helping to make the conference and this book possible and hope that our joint efforts will ultimately improve the care and understanding ... consciousness science carry substantial implications for our understanding of our place in nature, the specific objectives of coma science impose clear and present clinical and ethical challenges Here are ... (‘‘brain death’’) Bedside clinical and laboratory tests to determine brain death have been standardized and subjected to evidence-based analysis Their description is clinically crucial but is...
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Báo cáo sinh học: " Etiopathology of chronic tubular, glomerular and renovascular nephropathies: Clinical implications" docx
... dysfunction and inflammation leading to fibrosis and reduced filtration; (ii) creating hypoperfusion and ischemic scenarios compromising renal blood flow, and tubular and glomerular function; and (iii) ... selectivity and permissivity of the glomerular filtration barrier becomes altered, and the glomerular structure collapses and leads to sclerosis and scarring, reduced glomerular flow and filtration, ... increase of cytosolic calcium and inositol phosphate, prostaglandin synthesis and cellular contraction and long-term alterations such as proliferation, hypertrophy and ECM production [159] These...
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báo cáo hóa học: " Clinical implications of gait analysis in the rehabilitation of adult patients with "Prader-Willi" Syndrome: a cross-sectional comparative study ("Prader-Willi" Syndrome vs matched obese patients and healthy subjects)" docx
... adiposity- structural and functional limitations of obesity and implications for movement Obesity Rev 2002, 3:35-43 Must A, Strauss RS: Risks and consequences of childhood and adolescent obesity ... were obese and overweight Mean Body Mass Index (BMI) and Standard Deviation (± SD) were 41.3 ± 6.0 kg/m2 (range 29.3–50.1 kg/m2) Standing height was determined by a Harpenden Stadiometer and expressed ... "Istituto Scientifico Ospedale S Giuseppe" and they underwent clinical assessments and attended a rehabilitation program All patients showed the typical PWS clinical phenotype [16] Cytogenetic analysis...
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báo cáo hóa học:" Etiopathology of chronic tubular, glomerular and renovascular nephropathies: Clinical implications" pdf
... dysfunction and inflammation leading to fibrosis and reduced filtration; (ii) creating hypoperfusion and ischemic scenarios compromising renal blood flow, and tubular and glomerular function; and (iii) ... selectivity and permissivity of the glomerular filtration barrier becomes altered, and the glomerular structure collapses and leads to sclerosis and scarring, reduced glomerular flow and filtration, ... increase of cytosolic calcium and inositol phosphate, prostaglandin synthesis and cellular contraction and long-term alterations such as proliferation, hypertrophy and ECM production [159] These...
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Báo cáo khoa học: "Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications" doc
... study, drafted the paper and performed the statistical analysis, ACZ participated in the statistical analysis and drafted the paper, MAP contributed to the immunostainings and clinical data collection, ... of the female tract and the fourth most common cancer in women following breast, colorectal and lung cancer in the Western world [19] A substantial decrease in the incidence and mortality of endometrial ... the association of CAR expression and staining intensity with various clinicopathological parameters, tumor proliferative capacity and patient survival Patients and Methods Patients Forty-one endometrial...
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Báo cáo khoa học: "Clinical review: The implications of experimental and clinical studies of recruitment maneuvers in acute lung injury" pptx
... volumes, and the forces generated by repeated opening and collapse lead to upregulation of an inflammatory response, with release of cytokines and chemokines and activation of neutrophils and macrophages ... RMs can increase oxygenation and lung volume in collapsed prone lungs However, the benefits of RMs in terms of oxygenation and lung recruitment in ARDS patients and in experimental models with ... lung injury, and the long-term benefits and safety of RMs will depend on the extent of this effect Experimental evidence on recruitment maneuvers In saline lavaged rabbit lungs, Bond and coworkers...
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Báo cáo y học: "Science review: Extracellular acidosis and the immune response: clinical and physiologic implications" potx
... with sepsis induced by cecal ligation and puncture [46] Eighteen hours after cecal ligation and puncture, we randomly assigned 24 rats to three groups In groups and we began an 8hour intravenous ... 5–10 and 10–15 mEq/l, respectively We measured MAP, arterial blood gases, electrolytes, and plasma nitrate/nitrite levels at 0, 3, and hours MAP remained stable in group but decreased in groups and ... understanding of how pHo affects this response is necessary to interpret data from studies of immunomodulation; to avoid unintended immunomodulation in clinical and laboratory settings; and to...
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