from tibo to rilpivirine the chronicle of the discovery

... Introduction: The Essence of Life and the Labyrinth of the Genome The Invention of Biotechnology 1.1 The Origins of Biotechnology 1.2 The Emergence of a New Concept of Life 1.3 From Zymotechnology to Biotechnology ... 92 From Biotechnologyto Genomes:A Meaning for the Double Helix x The Foundations of the Heralded Revolution 3.1 From the Frontiers of Genetics to the Birth of Molecular Biology 3.2 The Secret of ... testifled to the vision of a science of the artificial l This tranhmihsion of the intenial movement of decomposition inside matter is at the heart of Liebig’s theory IL denieh any essential role to the...

Ngày tải lên: 08/04/2014, 12:48

... the ball forward But because the system is too complex to take into account all the factors involved— the speed of the ball, the speed of the wheel, the precise angle at which the ball hits the ... matter how the earth moves with respect to the background of distant stars, the speed of light remains the same This mystery of the speed of light and the existence, or nonexistence, of the ether was ... catalogs of books Many of these catalogs contain references to their own titles, as well as to those of other books But some of these catalogs not refer to themselves The librarian decides to make...

Ngày tải lên: 09/04/2014, 16:38

... between the direction of the magnetic field H and the direction of the magnetization M of the bar magnet [11] The product pl is the magnetization M of the bar [13] The work done by the torque gives ... Nevertheless, the Land´ g-factor results from the calculation of the first-order e perturbation of the energy of an atom when a weak external magnetic field acts on the sample [15,16] Normally, the ... Magnetic Moment of a Sample of N Atoms In a simple paramagnet, the atoms not interact with each other, and the ˆ only contributions to the Hamiltonian H come from their interaction with the applied...

Ngày tải lên: 04/06/2014, 15:18

... difficult to get the hang of it The difficulty stems not from there being lots of complicated rules to learn, but from the fact that there are so few In the field of probability it is not possible to ... opened to reveal the prize (or lack of it) The 14 From Cosmos to Chaos question is, when offered the choice, should the contestant stay where he is, swap to the other door, or does it not matter? The ... 0.50 The last two columns show the contributions of each arrangement to the probability of success of either playing for the drop or the finesse The drop is slightly more likely to work than the...

Ngày tải lên: 11/06/2014, 01:04

... “Marketing is not the art of finding clever ways to dispose of what you make Marketing is the art of creating genuine customer value It is the art of helping your customers become better off The marketer’s ... Change or die When the rate of change inside the company is exceeded by the rate of change outside the company, the end is near.” Tom Peters’ advice: To meet the demands of the fastchanging competitive ... customer questions Marketing is a larger process of systematically figuring out what to make, how to bring it to the customer’s attention and easy access, and how to keep the customer wanting to...

Ngày tải lên: 28/06/2014, 12:20

... “Marketing is not the art of finding clever ways to dispose of what you make Marketing is the art of creating genuine customer value It is the art of helping your customers become better off The marketer’s ... Change or die When the rate of change inside the company is exceeded by the rate of change outside the company, the end is near.” Tom Peters’ advice: To meet the demands of the fastchanging competitive ... customer questions Marketing is a larger process of systematically figuring out what to make, how to bring it to the customer’s attention and easy access, and how to keep the customer wanting to...

Ngày tải lên: 28/06/2014, 12:20

Ngày tải lên: 06/07/2014, 15:31

Ngày tải lên: 06/07/2014, 15:34

... (0.8 to 0.9) 0.9 (0.8 to 0.9) 15 to 24 1.8 (1.8 to 1.9) 2.0 (1.9 to 2.1) 1.9 (1.9 to 2.0) 25 to 34 4.1 (4.0 to 4.2) 4.7 (4.6 to 4.8) 4.4 (4.3 to 4.5) 35 to 44 10.1 (9.9 to 10.2) 12.8 (12.6 to 13.0) ... (52.6 to 56.6) 58.2 (55.8 to 60.7) 56.2 (54.7 to 57.7) >1 18.7 (18.0 to 19.5) 22.7 (22.0 to 23.5) 20.8 (20.24 to 21.3) to 1.9 (1.8 to 2.1) 2.3 (2.2 to 2.5) 2.1 (2.0 to 2.2) to 14 0.8 (0.9 to 0.9) ... 11.4 (11.3 to 11.5) 45 to 54 23.5 (23.2 to 23.7) 31.9 (31.6 to 32.2) 27.6 (27.4 to 27.8) 55 to 64 55.9 (55.5 to 56.4) 71.1 (70.5 to 71.6) 63.2 (62.9 to 63.6) 65 to 74 133.6 (132.8 to 134.5) 174.2...

Ngày tải lên: 13/08/2014, 15:22

... It also aims to improve the quality of life of the elderly by offering them the chance to remain active, including the chance to work Remodeling society to incorporate the needs of the elderly ... technology to meet the needs and wants of the target market 16 The significance of this is keyed to the expected rise in the number of single elderly households in Japan (see The agenda of ageing: The ... significant that the government has made the decision to turn these sectors into growth-driving industries Talking about the way to secure efficiency in the system, the quality of the workforce...

Ngày tải lên: 06/12/2015, 23:07

... confined to certain motor nuclei of the central nervous system (CNS) From the very beginning, these findings pointed to a possible neuromodulatory role for UII The aim of this review is to provide ... analysis of the receptor’s primary sequence shows striking similarities to the somatostatin receptor family, most notably in the transmembrane domains The pharmacological relatedness of somatostatin ... laboratory from rats show only diffuse URP mRNA expression in certain areas of the medulla oblongata that are not known to project to the PPT There will be a need to produce selective tools (antibodies,...

Ngày tải lên: 19/02/2014, 07:20

... to account for such factors In addition to examining the transfer of skills from Spanish to English, this study sought to examine the effects of level of Spanish literacy and oral English proficiency ... to examine the effects of performance on the Spanish reading components at the end of second grade on the rate of growth in English passage comprehension between the end of second grade and the ... comprehension The study focused on the extent to which the levels of skill achieved in these components of early reading in Spanish could predict the types of gains these children would make over the course...

Ngày tải lên: 24/02/2014, 18:20

... at the base of his policies in 1917 and after It was the commitment at the core of his concept of the dictatorship of the proletariat, and thus at the core of the major political features of the ... the morrow of the revolution Rather, there was a number of transitional steps to socialism: the first step in the revolution by the working class is to raise the proletariat to the position of ... Marxists It is to these critics we must turn for an appreciation of the dangers of Marx's project The pursuit of Utopia, or the adherence to Utopian ideals before about the time of the First World...

Ngày tải lên: 31/05/2014, 00:40

... that the value of the odds ratio can be used to interpret the internal variations in the use of descriptors among the respondents, that is, their expertise Thus, the respective estimate of the ... farmers (Table 2) These are the differences in the use of generic descriptors (p-value 0.05), and damage to maize descriptors (p-value 0.05) In the case of both of these descriptors, non-orphans ... categories: on one hand there are characteristics linked to the form of the living things (kind of pests; morphology and locomotion), and on the other hand there are descriptors linked to the functional...

Ngày tải lên: 10/08/2014, 09:21

... to say to everybody, / thanks them, / thanks them for coming” (16) The image of the mother becomes a universal image of grieving The repetition of “sometimes” and “thanks them” seem to slow the ... whilst the private is elevated to the mythic realm Critics of Glück’s poetry have tended to focus on the voice of the poet and not on the narrative structures of the books In the introduction to ... in the family, resulting in their avoidance of the possibilities of the present, the poet too has been guilty of the same But unlike her parents, the poet also learns that to dwell on forms of...

Ngày tải lên: 06/10/2015, 21:22

... within the modernizing imperial family of man I attend to narrative structure, and to the kind of stories that get told and retold about the Irish, so as to reveal both the regularity of English ... state of Irish society Because efforts to legitimate English rule in Ireland so often involve disputed rights to land and property, the relation of fathers to sons, of mothers to daughters, and of ... child of Union punishes its mother from within and threatens its father, too, ‘‘across the water’’ () The ‘‘legacy’’ () of force and violence, the poem suggests, is more of the same: the crossing...

Ngày tải lên: 21/09/2012, 10:39

... such as the port of entry, the names of the importer and exporter, a detailed description of the goods, the quantity of the goods, the value of the goods, the currency, and the country of origin ... market of the company’s products is North Vietnam The area’s consumption accounted for up to 87% of the total sales of the company in 2011 The Central Vietnam and the others took up the last 13% of ... deciding all company’s activities The two vice-directors assist the director in running the company They are responsible to the director for the functioning of their department Võ Thị Khánh Chi...

Ngày tải lên: 24/07/2013, 09:11

... just be too busy to document what they know due to the complexity of the task and the time that it takes to complete it There is also the possibility that social actors might be unwilling to articulate ... Schultze, 1998) There is therefore an imperative to capture the ontological and epistemological perspectives of IS developers if the product of their development efforts are to be fully understood IMS’s ... unwilling to articulate how they go about their business simply because in so doing they run the risk of making themselves dispensable As indicated, the reluctance of users to express their knowledge...

Ngày tải lên: 20/12/2013, 19:15

... contribution of the systematic factor and the regulation to the total timely variation of the exposure is 17.24% and, therefore, 82.76% of the variation is due to idiosyncratic effects These effects ... however the explanatory power, measured by the R2 , is relatively low (4.08% compared to the R2 of the corresponding within- regression of 30.48%), for the other banking groups (apart from the regression ... due to changes in the systematic component of the exposure to interest rate risk μ(t) or whether the composition of banks in the sample (α(t) − α(t − 1)) has changed, or whether changes in the...

Ngày tải lên: 16/02/2014, 06:20

... Clerks of the Roads, viz.:—Two of the Northern Road, two of the Chester Road, two of the Eastern Road, and Two of the Western Road In 1677, there were, in addition to these Roads, the Bristol Road ... sent to the Right Hon Wm Pitt, representing the great benefits received from the plan, and requesting a continuance of the same, together with the extension of the same plan to other parts of the ... cost of conveyance was only a small item in the expenses of the Post Office The Mayor of Bath proposed the toast of "the Visitors," and said that they had amongst them two representatives of the...

Ngày tải lên: 17/02/2014, 02:20