... endeavor to be responsive to changing public health needs and to the scientific and technological opportunities that come our way. Our Vision A Nation free from the suffering and death due to cancer ... and test techniques to screen people for risk factors using gene assessment and imaging technologies, clinical pr esentation, and data on lifestyle, family histor y , and environmental factors. ... Standards and Technology and the U. S. Food and Drug Administration to establish the Nanotechnology Characterization Laboratory (NCL). Scientists at the NCL perform preclinical efficacy and toxicity...
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... availability of toilets, increased advocacy and education will be necessary to convince people to use the toilets, to create separate male and female toilets in schools, and to promote proper ... families and communities, and individuals who work hard to contribute to those communities. Too many of these individuals die before having a fair chance at life, and many more live, but are left to ... recognizing symptoms of dehydration and properly managing diarrhoea, and on promoting these practices to mothers. It is usually diarrhoea which first brings babies into contact with doctors and the...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) pptx
... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) Harrison's Internal Medicine > Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss Definitions ... more chronic, and they may vary from mild to very severe. The site of hemolysis may be predominantly intravascular or extravascular. With respect to mechanisms, HAs may be due to intracorpuscular ... mild hereditary spherocytosis or with cold agglutinin disease may be diagnosed after years. This is due in large measure to the remarkable ability of the body to adapt to anemia when it is slowly...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 2) docx
... 5 mM) goes hand in hand with the gradual loss of cellular organelles and of biosynthetic abilities. In the end the erythroid cell undergoes a process that has features of apoptosis, including ... pyknosis and actual loss of the nucleus. Reticulocytes Increased Bilirubin Increased (mostly unconjugated) LDH Increased (up to 10X normal with intravascular hemolysis) Haptoglobin Reduced to ... lactate dehydrogenase (LDH), increased aspartate transaminase, and reduced haptoglobin. Urobilinogen will be increased in both urine and stool. If hemolysis is mainly intravascular, the telltale...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) pptx
... Chronic iron overload will cause secondary hemochromatosis; this will cause damage, particularly to the liver, eventually leading to cirrhosis, and to the heart muscle, eventually causing heart failure. ... components in the red cell: (1) hemoglobin, (2) the membrane-cytoskeleton complex, and (3) the metabolic machinery necessary to keep (1) and (2) in working order. Here we will discuss diseases of ... pathophysiologic process common to all HAs is an increased red cell turnover. The gold standard for proving that the life span of red cells is reduced (compared to the normal value of about 120...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) ppt
... glycosylated, and they carry antigenic determinants that correspond to blood groups. Underneath the membrane, and tangential to it, is a network of other proteins that make up the cytoskeleton. The ... (including ankyrin and the so-called band 4.1 and band 4.2), which thus connect these two structures intimately. Figure 101-2 Diagram of red cell membrane/cytoskeleton. (For explanation ... instead autosomal recessive (with the patient being homozygous). Figure 101-3 Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) Hemolytic Anemias Due to Abnormalities...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) doc
... Anemias and Anemia Due to Acute Blood Loss (Part 6) Peripheral blood smear from patients with membrane-cytoskeleton abnormalities. A. Hereditary spherocytosis. B. Hereditary elliptocytosis, ... elliptocytosis, heterozygote. C. Elliptocytosis, with both alleles of the α-spectrin gene mutated. [From L Luzzatto, in J Gribben and D Pravan (eds): Molecular Hematology, 2d edition. Oxford, Blackwell, ... Blackwell, 2005; with permission.] Table 101-3 Inherited Diseases of the Red Cell Membrane- Cytoskeleton Gene Chromoso mal Location Protei n Produced Disease( s) with Certain Mutations Comment s...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) docx
... prophylaxis postsplenectomy is controversial. 4. HS patients often may require cholecystectomy. It used to be considered mandatory to combine this procedure with splenectomy, but this may not ... HE causing clinical disease is similar to that of HS. However, an asymptomatic form, referred to as Southeast Asian ovalocytosis, has a frequency of up to 7% in certain populations, presumably ... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) Clinical Presentation and Diagnosis The spectrum of clinical severity of HS is broad....
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) pdf
... Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) Abnormalities of the Glycolytic Pathway (Fig. 101-1) Since ... jaundice; the jaundice persists and is usually associated with a very high reticulocytosis. The anemia is of variable severity; sometimes it is so severe as to require regular blood transfusions; ... be delayed, and in some cases it is made in young adults—for instance, in a woman during her first pregnancy, when the anemia may get worse. In part the delay in diagnosis is due to the fact...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 9) ppsx
... directly and via reduced glutathione (GSH), defends these cells against oxidative stress. G6PD deficiency is a prime example of an HA due to interaction between an intracorpuscular and an extracorpuscular ... decrease in G6PD activity in most tissues, this is less marked than in red cells, and it does not seem to produce symptoms. Figure 101-4 Diagram of redox metabolism in the red cell. G6P, glucose ... system, or both. The diagnosis of HA is usually not difficult, thanks to the triad of normo-macrocytic anemia, reticulocytosis, and hyperbilirubinemia. Enzymopathies should be considered in the...
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) pps
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) doc
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 12) doc
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 13) pptx
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 14) pps
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 15) potx
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 16) ppt
Ngày tải lên: 07/07/2014, 04:20
Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 17) potx
Ngày tải lên: 07/07/2014, 04:20
C++ - I/O Streams as an Introduction to Objects and Classes
... beginning to the end (for now) No backing up to read something again (OK to start over) Just as done from the keyboard Writing to a file Sending output to a file Done from beginning to end ... Files? Files allow you to store data permanently! Data output to a file lasts after the program ends An input file can be used over and over No typing of data again and again for testing Create ... up to write something again( OK to start over) Just as done to the screen Slide 6- 5 Copyright â 2007 Pearson Education, Inc. Publishing as Pearson Addison-Wesley I/O Streams I/O refers to...
Ngày tải lên: 12/09/2012, 22:49