... human and rat CB1 receptor The CB2 antibody was raised against a sequence between the N-terminal and the first transmembrane domain of the protein of the human and rat CB2 receptor The specificity of ... marrow stem cells, are the most potent antigen-presenting cells of the immune system They play a central role in the initiation of primary immune response and in the enhancement of secondary immune ... for AEA, PalEtn and 2AG, respectively Analysis of cannabinoid receptors and fatty acid amide hydrolase To determine the presence of the cannabinoid receptors (CB1 and CB2) and of the fatty acid...
Ngày tải lên: 22/02/2014, 07:20
... The spin axes of the Sun and the planets 7.4.1 Spin axes and the Solar Nebula Theory 7.4.2 Spin axes and the Modern Laplacian Theory 7.4.3 Spin axes and the Accretion Theory 7.4.4 Spin axes and ... Newton the basic structure of the solar system and the laws that govern the motions of the bodies within it have been well understood One central body, the Sun, containing most of the mass of the system ... picture of the origin and evolution of the solar system is the Capture Theory developed by the author and colleagues since the early 1960s This explains the basic structure of the solar system...
Ngày tải lên: 17/03/2014, 13:35
Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx
... 90–15) and 255 (M+ – 131) The loss of mass 131 results from the scission of the C1–C2 and C4–C5 bonds Figure 4C illustrates mass spectra of isolated 7-DHP-MO-TMS, and the synthesized standard The ... (Invitrogen), and the isolation of RNA followed the manufacture’s protocol The synthesis of first-strand cDNA was performed using the Superscript preamplification system (Invitrogen) Either lg of total ... investigation on the cutaneous expression of each of the components of the P450scc enzymatic system In addition, we tested reconstituted and mitochondrial P450scc systems for their ability to...
Ngày tải lên: 23/03/2014, 13:20
woolfson m.m. origin and evolution of the solar system
... The spin axes of the Sun and the planets 7.4.1 Spin axes and the Solar Nebula Theory 7.4.2 Spin axes and the Modern Laplacian Theory 7.4.3 Spin axes and the Accretion Theory 7.4.4 Spin axes and ... Newton the basic structure of the solar system and the laws that govern the motions of the bodies within it have been well understood One central body, the Sun, containing most of the mass of the system ... picture of the origin and evolution of the solar system is the Capture Theory developed by the author and colleagues since the early 1960s This explains the basic structure of the solar system...
Ngày tải lên: 24/04/2014, 17:26
Báo cáo sinh học: "Parasite immunomodulation and polymorphisms of the immune system" ppsx
... deeper understanding of the intimate co-evolution of pathogens and the immune system 10 11 12 13 14 Acknowledgements The author’s research is supported by grants from the Wellcome Trust, the Medical ... pathogens demanding conflicting response patterns, the fine-tuning effect of multiple allelic variants allows the immune system to be variably calibrated across the population In the absence of infection, ... to the development of damaging immune reactions in autoimmunity and allergy The identification of precise genetic variants controlling both parasite susceptibility and immunopathology offers the...
Ngày tải lên: 06/08/2014, 19:20
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 1 pps
... understanding of the anatomy and function of the ear and the auditory nervous system, and it discusses the cause and treatment of hearing disorders Most books on hearing focus either on the anatomy ... comprehensive coverage of disorders of the auditory system emphasizing the interaction between pathologies of the middle ear and the cochlea and the function of the nervous system and vice versa Hyperactive ... function of the cochlea than of any other sensory organ C H A P T E R Anatomy of the Ear ABSTRACT 10 The ear consists of the outer ear, the middle ear and the inner ear The outer ear consists of the...
Ngày tải lên: 11/08/2014, 06:21
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 2 ppsx
... at the entrance of the ear canal compared with the sound pressure that is measured in the place of the head The effect of the head on the sound at the entrance of the ear canal is related to the ... ratio between the effective area of the tympanic membrane and the area of the stapes footplate, but the lever ratio of the middle ear bones also contributes The ratio of areas of the BOX 2.2 SOUND ... remarkable in the light of the FIGURE 2.12 (A) Average displacements of the umbo, the head of the stapes and the lenticular process of the incus (B) The lever ratio at 124 dB SPL at the tympanic...
Ngày tải lên: 11/08/2014, 06:21
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 4 potx
... between the classical and the non-classical auditory pathways While the ICC is a part of the classical ascending auditory system the ICX and the DC are parts of the non-classical auditory system The ... in the ventral parts of the MGB of the thalamus, the nonclassical sensory pathways use the dorsal and medial division of the MGB as relay (Fig 5.10) [122] These divisions of the MGB receive their ... of the fourth ventricle (Fig 5.15B) [72] The other part of the olivocochlear system projects mainly to the contralateral cochlea and the fibers of that system travel deeper in the brainstem The...
Ngày tải lên: 11/08/2014, 06:21
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 6 pot
... The caudal portion of the floor of the lateral recess is the (dorsal) surface of the dorsal cochlear nucleus and the rostral portion of the floor of the lateral recess is the dorsal surface of ... difference between the latency of the N1 of the AP and that of the response from the intracranial portion of the auditory nerve is the travel time in the auditory nerve from the ear to the recording ... the latency of the first peak in the dipole and the length is the relative strength of the dipoles Note the short distance between the two first dipoles (peak I and II of the ABR) and the third...
Ngày tải lên: 11/08/2014, 06:21
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 7 pot
... and standard error of the mean are shown as a function of the intensity of the noise The TTS was measured 20 s after the end of the exposure In this study the noise exposure consisted of a band ... basis of the elevation of the hearing threshold in disorders of the middle ear and the cochlea but the effect on the function of the nervous system may affect speech discrimination Impairment of speech ... decreases the input to the cochlea and thereby decreases the contraction of the stapedius muscle, and that in turn causes the input to the cochlea to again increase, and that increases the contraction...
Ngày tải lên: 11/08/2014, 06:21
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 8 docx
... increase the sensitivity and frequency selectivity of the ear (cf Chapter 3) The widening of the tuning of the basilar membrane broadens the “slices” of the spectrum of broad band sounds from which the ... this view of flexibility of the function of the auditory system That injury and loss of cochlear hair cells can cause profound changes in the structure and function of the central auditory system ... perpendicular to the surface of the flat portion of the incudo-stapedial joint and that does not cause any movement of the incus and thus no displacement of the tympanic membrane If the pressure in the perilymphatic...
Ngày tải lên: 11/08/2014, 06:21
ANATOMY, PHYSIOLOGY, AND DISORDERS OF THE AUDITORY SYSTEM - PART 9 pdf
... range of sound intensities [58] The number of channels that are required depends on the resolution of coding of the intensity of sounds in these frequency bands [184] If the resolution of the coding ... corresponding to the F1 frequency and the other corresponding to the frequency of F2 The rate of the impulses is that of F0 for voiced sounds, and a quasi-random rate (average of 100 pps) for ... determined on the basis of the output of 16 band-pass filters The output of the six band-pass filters with the largest amplitudes is coded in the impulses that are applied to the electrodes in the cochlea...
Ngày tải lên: 11/08/2014, 06:21
Minsky on the reregulation and restructuring of the financial system
... Commission, UK Financial Services Authority, and, in the United States, the Office of the Comptroller of the Currency, the Securities and Exchange Commission, and the Federal Reserve. For their joint review, see SSG 2008. ... system, the cost of such resolution to the general fund of the Treasury, and the potential of such seizure and resolution for increasing excessive risk taking going forward). In the view of Joshua Rosner (2011), there is a fundamental flaw in the OLA process caused by the fact ... of life), the Act mandates the formulation of so‐called “living wills” in the form of the preparation of resolution plans and credit exposure reports. The Act calls upon the Board of Governors of the Fed to require nonbank financial companies and bank ...
Ngày tải lên: 23/09/2015, 08:52
Design and analysis of the intake system of a formula SAE car
... Near the end of the compression stroke, the spark ignites the compressed air-fuel mixture, raising the temperature of the gases in the cylinder to the range of few thousands of degrees, and increasing ... supplied to the engine, otherwise known as the “charge” of the engine In the scenario where the only method of charging the engine is by the vacuum pressure created by the expanding of the combustion ... intake system, to reduce the impact of the air restrictor on the entire engine system Location of Engine The dominant design of the Formula SAE race car has the engine located in the rear of the...
Ngày tải lên: 04/10/2015, 10:25
Basic immunology functions and disorders of the immune system
... each of these features is discussed in more detail THE EARLY INNATE IMMUNE RESPONSE TO MICROBES The principal barriers between the host and the environment are the epithelia of the skin and the ... affinity of the leukocyte integrins for their ligands on the endothelium Concurrently, TNF and IL-1 act on the endothelium to stimulate expression of ligands for integrins The firm binding of integrins ... Potential for immunotherapy of cancer FIGURE 1-1 The importance of the immune system in health and disease This table summarizes some of the physiologic functions of the immune system Note that...
Ngày tải lên: 04/08/2016, 15:18
Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion pdf
... the lung (Fig 2) [9] The kyphotic curvature of the spine and the anteroposterior diameter of the chest increase with aging, thereby decreasing the curvature of the diaphragm and thus its force-generating ... in the compliance of the chest wall, the lung, and the respiratory system between an ‘‘ideal’’ 20-year-old (A) and a 60-year-old subject (B) Note increase in RV and FRC and decrease in slope of ... small 471 aging of the respiratory system 70 60 FRC % TLC 50 40 RV 30 20 10 10 20 30 40 50 60 70 Age (years) Fig Progressive and linear increase in RVand FRC between the ages of 20 and 60 years...
Ngày tải lên: 05/03/2014, 21:20
Report and Recommendations of the Cross-border Bank Resolution Group potx
... for the resolution of cross-border financial groups However, the development of mechanisms for the sharing of financial burdens for the resolution of future Report and Recommendations of the ... funding and deposit insurance or other guarantee coverage; Determination of the competent authority for the resolution proceedings of all component parts of the group and for the coordination of these ... jurisdictions and the law and policy in those jurisdictions In the EU/EEA, the European Directives on the Reorganisation and Winding-up of Credit Institutions of April 2001 and of Insurance Undertakings of...
Ngày tải lên: 06/03/2014, 09:20
PROTOCOL ON THE STATUTE OF THE EUROPEAN SYSTEM OF CENTRAL BANKS AND OF THE EUROPEAN CENTRAL BANK pdf
... 17 of the Act concerning the conditions of Accession of the Czech Republic, the Republic of Estonia, the Republic of Cyprus, the Republic of Latvia, the Republic of Lithuania, the Republic of ... equal to the sum of: — 50% of the share of its respective Member State in the population of the Community in the penultimate year preceding the establishment of the ESCB; — 50% of the share of its ... annual report on the activities of the ESCB and on the monetary policy of both the previous and the current year to the European Parliament, the Council and the Commission, and also to the European...
Ngày tải lên: 06/03/2014, 10:20
manual on the application of the haccp system in mycotoxin prevention and control pdf
Ngày tải lên: 17/03/2014, 16:20
Báo cáo khoa học: "REVERSIBLE AUTOMATA AND INDUCTION OF THE ENGLISH AUXILIARY SYSTEM" doc
... out of 44 variants and the passive system from 14 out of 22 The entire active system is learnable once examples of each form of each verb and each modal have been seen, plus one example to fix the ... force the separate tre.atment of active versus passive forms Then if, say on considerations of frequency of occurrence, exceptions were externally handled and the infrequent The auxiliary system ... inferential power and the proper handling of exceptions For l-reversible inference, 45 of the verb sequences of length three or shorter will yield the remaining nine such strings and nonc longer...
Ngày tải lên: 24/03/2014, 01:21