floor ceiling effects in children with sickle cell disease

... by pain from your joint in bed at night?' and I10 'Has pain from your joint kept you awake during your night-time sleep?' were explored in separate analyses The model with item I6, resulted in ... remaining standing for 30 minutes increase your pain? 1.38 -4.25 (0.73) -2.39 (0.29) -1.22 (0.16) -0.07 (0.11) I2 What degree of difficulty you have bending and rotating your affected joint? ... analysis resulted in P items being retained and eleven items being removed including the one item already removed due to having greater than 10% missing data (see Table where items in bold were removed)...

Ngày tải lên: 18/06/2014, 18:20

... were observed in the NOESY spectrum of the mixture, an interaction of the two single domains and the formation of one single Cu(I)-containing domain with the involvement of both domains could be ... intact protein and separated domains would also argue against this proposal [26] Luminescence titration series also provide noteworthy information Luminescence intensities increased almost linearly ... two-domain protein, for example, is composed of a Cu(I)4S9 cluster in the N-terminal b-domain and a Zn(II)4S11 cluster in the C-terminal a-domain [10,11] Examples for solely Cu(I) binding MTs...

Ngày tải lên: 07/03/2014, 09:20

... kind which yield information on number rings and their class groups In this paper, we begin by deriving a general law of composition on 2×2×2 cubes of integers, from which we are able to obtain ... be interested in studying commutative rings R with unit whose underlying additive group is Zn for n = 2, 3, 4, and 5; such rings are called quadratic, cubic, quartic, and quintic rings respectively.6 ... discriminant of a binary quadratic form equals the discriminant of the corresponding quadratic ring Restricting the above result to the set of primitive quadratic forms, and noting that, in the...

Ngày tải lên: 14/03/2014, 22:20

... returned, at dinner-time, he carried the brick, enveloped in many series of papers, beginning with the coarsest kind and ending with the finest kind; and each of the wrappers was fastened with its ... grandfather, facing page 20, is from a photograph by Sir David Brewster, taken in St Andrews in 1846 or 1847 The subject sat in his own garden, blinking at the sun for many minutes, in front of the ... for a long time in front of a certain candy-shop window, in which was displayed a little regiment of lead soldiers, marching in double file towards an imposing and impregnable tin fortress on...

Ngày tải lên: 23/03/2014, 05:20

... used in the rescue of recombinant influenza will function only in primate or avian cells [5-7] In order to rescue influenza using the RNA pol I transcription machinery in canine cells, cloning ... vaccines for human vaccination is in most cases an egg-base process, many vaccine manufacturers are actively developing cell- based influenza vaccine capabilities Cell- based influenza vaccine ... sequencing kit (USB) Cell culture and transfection MDCK cells were originally obtained from the American Type Culture Collection and were maintained in MEM supplemented with 10% fetal bovine serum...

Ngày tải lên: 18/06/2014, 18:20

... behavior during reaching and grasping can be understood from the endpoint behavior, the action representation shown in Figure does not include the monitoring of fingers and grasping as a continuous ... perception In reach and grasp movements, the end-point, as the major interactor with the environment and the action goal, becomes the common planning anchor Reaching trajectories involving multiple joints ... understanding of embodied interaction and the development of interactive interfaces Embodied interaction stresses the importance of knowledge gained through the body’s experience interacting with...

Ngày tải lên: 19/06/2014, 08:20

... used in the rescue of recombinant influenza will function only in primate or avian cells [5-7] In order to rescue influenza using the RNA pol I transcription machinery in canine cells, cloning ... vaccines for human vaccination is in most cases an egg-base process, many vaccine manufacturers are actively developing cell- based influenza vaccine capabilities Cell- based influenza vaccine ... sequencing kit (USB) Cell culture and transfection MDCK cells were originally obtained from the American Type Culture Collection and were maintained in MEM supplemented with 10% fetal bovine serum...

Ngày tải lên: 20/06/2014, 01:20

... h–1) kinetics of the thinned and control trees for two days per year (DOY) Days are chosen with similar PET Heavy line: PET; black lines: thinned oaks; grey lines: control oaks; grey line with ... transpiration diverged strongly with linearity with increasing PET (Fig 5), with an inflexion point around PET = mm d–1 The T/PET relationship was therefore characterised linearly for PET < mm d–1 (Tab ... ΣT/ΣPET inter-annual variation with oak LAI is larger in the thinned plot, whereas in the control one, ΣT/ΣPET increases with oak LAI Yet, both plots ΣT/ΣPET relationships with LAI are consistent with...

Ngày tải lên: 08/08/2014, 00:22

... drain was placed Finally the resected specimen was removed through this incision The fascial and skin incisions were closed with absorbable sutures The total procedure time was 180 minutes The total ... the hardware, drapes, and maintenance of the robotic system The robotic approach in gastrointestinal tract surgery has also a learning curve period regard to suturing technique, but we believe ... Finally, the robotic approach to the complex hepatobiliary surgery is feasible and safe in selected patients Three-dimensional visualization, articulating instruments, and fine-motion filtering...

Ngày tải lên: 09/08/2014, 03:22

... feel severe right ankle pain without any trigger events Although treatment, including physiotherapy and NSAID administration, was initiated in another clinic, the pain in his ankle progressively ... About nine months earlier, he began to feel severe right foot pain without any trigger events Although treatment, including physiotherapy and NSAID administration, was initiated in another clinic, ... increase in radioactivity in the bones of his foot (Figure 5C) These clinical findings were consistent with CRPS I according to the criteria [2] described for our first patient Lumbar bone mineral...

Ngày tải lên: 10/08/2014, 23:22

... identified in the developing human hypothalamus where the protein may be involved in neuropeptide vesicle trafficking [7,8] Children with newly-diagnosed CF have transiently-elevated intracranial ... genetic disease in the Caucasian population, with an incidence of one in 1500 to one in 4000 live births [1] An association between CF and Chiari malformation has been previously reported in eight ... following day At one-year follow-up with the Cystic Fibrosis Clinic and the Neurosurgery Service, our patient was continuing to well with no signs or symptoms of increased intracranial pressure or problematic...

Ngày tải lên: 10/08/2014, 23:22

... cavity was lined with a variable thickness of non keratinized stratified squamous epithelium with arch-shaped appearance and exocytosis in the underlying connective tissue was severely infiltrated ... treatment plan in DD [13] Another approach for the treatment of teeth with DD has included peri-apical surgery and retrograde filling, which is recommended in teeth with long roots [13,14] Since these ... Ground section view with stereomicroscope showing normal coronal dentin and irregular dentine obliterating the pulp chamber pulp necrosis and peri-apical abscess Follow-up and routine conservative...

Ngày tải lên: 11/08/2014, 14:21

... is in compliance with all ethical standards in Page of medicine Informed consent, including the publication of the study, was obtained from all patients according to the Declaration of Helsinki ... http://arthritis-research.com/content/13/4/R119 Introduction Specific autoantibodies in systemic rheumatic diseases are useful biomarkers associated with certain diagnoses and/or clinical manifestations [1] Several autoantibodies, including ... dominant nucleolar staining compared with their nuclear staining Case had ACA in addition (Figure 1B panel 5) Levels of anti-RNAP III were tested by ELISA comparing cases with atypical presentation...

Ngày tải lên: 12/08/2014, 17:22

... of increasing quantities of ΔNH2p65-tag protein in the 3T3-p65ko cell line – maintaining the p65wttag protein concentration as invariable – showed that NFκB-dependent activation increased in ... 1,0 Figure Binding affinity assay of p65wt-tag and ΔNH2p65-tag to IκBα by using in vitro translated proteins Binding affinity assay of p65wt-tag and ΔNH2p65-tag to IκBα by using in vitro translated ... the HIV-1 LTR contains several additional DNA binding domains that bind other cellular transcriptional factors, only NF-κB and Sp1 binding sites are really indispensable for initiation of HIV-1...

Ngày tải lên: 13/08/2014, 05:21

... 0.005 *Including both HIV-1 single and HIV-1 + HIV-2 dual infections †Including only HIV-2 single infections ‡ MRR = Mortality rate ratio, comparing with HIV-negative § CI = confidence interval ... participating † CI = confidence interval All retrovirus-associated mortality We compared mortality for co-infected individuals with mortality for single infected individuals Among 1,069 individuals with ... identifying diseases associated with HTLV-I infection in this area We have previously found that dual retroviral infections are more common in women than in men, and that the prevalence increases with...

Ngày tải lên: 13/08/2014, 05:22

... ribonucleoprotein A2/B1 dynactin zinc finger protein 265 Ras-related GTP binding C ubiquitin carboxyl-terminal esterase L5 destrin gam m a-am inobutyric acid receptor associated protein arsA (bacterial) ... light-chain subunit of dynactin complex (p24); dynactin complex involved in vesicle movement; dynactin complex interacts with NuMA and dynein in order to tether microtubules at the spindle poles ... Conclusion The Tax oncoprotein is considered the cause for mitotic aberrations in HTLV-I infected cells In addition to binding checkpoint factors and interfering with the MSC function, we propose...

Ngày tải lên: 13/08/2014, 09:20

... Note the Merino dam effects will be absorbed into this last term The genotype of the F1 sire is assumed to be Qq, with Q originating from the Awassi line and q from the Merino line Since there ... rate using combined linkage and linkage disequilibrium mapping Genetics 2002, 161(1):373-379 Meuwissen THE, Goddard ME: Mapping multiple QTL using linkage disequilibrium and linkage analysis information ... birth in spring till the end of autumn, a period of no growth or decline coinciding with winter, and a subsequent cycle between 52 and 98 weeks The points of change in growth (break points) were...

Ngày tải lên: 14/08/2014, 13:21

... English a teaching b teaches c teach d doesn't teaches > b 150 We have much in the rainy season a rainy b rain c raining d rains > b 151 The Bakers lunch a having b is having c are having d has ... in / on b one / in c in / in d at / in > c 124 Her birthday is August the third She always gets a lot of presents her birthday a on / on b in/ in c on / in d in / at > a 125 Nam is learning ... Can d Must > a 110 The weather is hot in Vietnam a in winter b in summer c in spring d in autumn > b 111 Mr Dickson is very tall and big He needs a raincoat a large size b short c long and...

Ngày tải lên: 05/11/2012, 09:18

... (NH4)2CO3 + Câu 10 Chọn A liên kết ion Cl- NH Câu 11 H2N-CH2-COOH3N-CH3 sản phẩm phản ứng glyxin metyl amin H2N – CH2 – COOH + CH3-NH2 → H2N-CH2-COOH3N-CH3 => Chọn D Câu 12 khối lượng bình brom tăng ... giảm nồng độ chất cân dịch chuyển theo chiều làm tăng nồng độ chất Câu 16 Chọn C glixerin trioleat este glixerin axit oleic có cấu tạo: (CH3- [CH2]7 – CH = CH- [CH2]7 - COO)3C3H5 => có phản ứng ... Dương – Sơn Dương – Tuyên Quang Câu 48 Chọn D Vì điều kiện nên tỉ lệ thể tích tỉ lệ số mol => Crackinh mol A mol hỗn hợp khí Y MY = 12.2 = 24 => mY = 24.3 = 72g Theo định luật bảo toàn khối lượng...

Ngày tải lên: 30/06/2013, 01:27

... attention, such as skiing, snowboarding, skydiving, hang-gliding, rock climbing, backpacking, and adventure tourism Some recreational activities are made illegal such as gambling and drug use Research ... the best answer by circling the letter A, B, C or D (2.0 pts) They are whispering to avoid by their friends A being heard B hearing C to be heard D being hearing Watching television is one ... B collecting C to collect D collected In some Western countries, many old-age parents like to live in a house because they want to lead independent lives A printing B guest C nursing D private...

Ngày tải lên: 02/07/2013, 01:25