findings from a randomized clinical trial
Báo cáo khoa học: Intermonomer cross-linking of F-actin alters the dynamics of its interaction with H-meromyosin in the weak-binding state ppt
... (p-PDM), ATP, ADP were from Sigma Chemical Co., (St Louis, MO) All other reagents were of analytical grade Ca2+-independent bacterial transglutaminase was a generous gift from K Seguro (Ajimoto ... adenosine 5¢[bc-imido] triphosphate (AMPPNP) complex was used as HMM ⁄ ATP state and HMM ⁄ ADP ⁄ AlF4 complex represents a stable analogue of HMM ⁄ ADP ⁄ Pi state The half-life of the ADP ⁄ AlF4 ... (Ajimoto Co Inc., Kawasaki, Japan) Proteins Rabbit skeletal muscle a- actin was isolated from an acetone powder of the hind-leg and back muscles of domestic white rabbits [28] HMM was prepared by chymotryptic...
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Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot
... AKETLDLRAHLKQVKKEDTEK AKESLDLRAHLKQVKKEDTEK GLCHPRVKVGNEYVTKG APKKDVKKPAAAAAAPAPAPAPAPAPAKPKEEKIDL APKKDVKKPAAAA PKYVKQATLKLAT Ó FEBS 2002 5090 V B Patchell et al (Eur J Biochem 269) a stock ... human ventricular MLC1 increased the contractility of intact and skinned human heart fibres [43] and a similar peptide added to rat cardiac myofibrils induced a supramaximal increase in the MgATPase ... Geisterfer-Lowrance, A. A.T., Kass, S., Tanigawa, G., Vosberg, H.P., McKenna, W., Seidman, C.E & Seidman, J.G (1990) A molecular basis for familial hypertrophic cardiomyopathy – a beta-cardiac myosin heavy-chain...
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descartes and the puzzle of sensory representation feb 2010
... (Alanen (1994), p 244); and “[…] material falsity would differ from formal falsity not because Cartesian sensations as qualia 37 Moreover, this interpretation of Cartesian sensations as qualia ... attempted to argue that Cartesian sensations are representational Even among those who agree that Cartesian sensations are representational, only a few try to provide an explicit account of what makes ... to maintain that abstract ideas are abstract objects really distinct from both the finite mind and particular objects, since it is possible to think of abstract ideas as general and innate ways...
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báo cáo sinh học:" The course of specialization in public health in Rio de Janeiro, Brazil, from 1926 to 2006: lessons and challenges Monireh Obbadi" ppt
... [dissertação de Mestrado] Rio de Janeiro: Escola Brasileira de Administração Pública, Fundação Getulio Vargas (EBA/FVG) 1985 Flexner A: Medical Education in the United States and Canada [A report ... Pública para os anos 90 Cad de Saúde Pública, RJ 1989, 5(4):361-364 Labra ME: O Movimento Sanitário nos anos 20 Da “Conexão Sanitária Internacional” Especialização em Saúde Pública no Brasil [dissertação ... Teixeira LA: Cobras, lagartos & outros bichos Uma história comparada dos institutos Oswaldo Cruz e Butantan Rio de Janeiro: Editora UFRJ Fiocruz 1993, 228 Santos LAC, Faria L: O ensino da saúde...
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báo cáo hóa học: "On the identification of sensory information from mixed nerves by using single-channel cuff electrodes" pot
... the ANN was not repeatable since it was initiated from random initial weights, and sought local minimum errors rather than global ones Instead, for the SVM it was repeatable and fast The SVM can ... Sanitaria of Spain Page 14 of 15 Author Details 1ARTS Lab, Scuola Superiore Sant'Anna, Piazza Martiri della Liberta' 33, Pisa, Italy, 2Institute of Neurosciences and Dept Cell Biology, Physiology and ... Universitat Autònoma de Barcelona (UAB), E-08193 Bellaterra, Barcelona, Spain, 3Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), E-08193 Bellaterra, Barcelona,...
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Báo cáo y học: "vitamin B12 status in patients of Turkish and Dutch descent with depression: a comparative cross-sectional study" pot
... homocysteine was released using the Fa BioRad kit (Bio-Rad Quantaphase kit; Bio-Rad Clinical Division, Hercules, Calif) Statistical analysis The patient features were analysed via descriptive statistics ... 7.95 a2 test clinical data and vitamins and tHcy A P value < 0.05 was viewed as statistically significant The statistical calculations were performed using the SPSS 11.5.1 software program (SPSS ... alignment and drafted the manuscript PvL participated in the sequence alignment and drafted the manuscript All authors read and approved the final manuscript http://www.annals-general-psychiatry.com/content/8/1/18...
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Báo cáo y học: "Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis" potx
... assessment and analysis of the protein data and participated in writing the manuscript AS, EB, and CBSW assessed and analyzed the mRNA data EPK critically read and edited the manuscript FE and RB participated ... high variability from animal to animal, resulting in a lack of statistical significance In AIA, therefore, the role of systemic TNF-α appears marginal, at least in relation to other cytokines, as ... antigen-induced arthritis (AIA) (day 0) or afterwards (at hours and on days 1, 3, and 6) Data were originally expressed as ng/mg total protein and then related to values of day (fold change; peak values...
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Báo cáo y học: "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis" docx
... animals and clinical onset occurs at approximately day 15 after immunization The paws of the rats were monitored daily for visual inflammatory signs such as erythema and swelling by means of a previously ... Netherlands), and a polyclonal ligand affinity-purified goat anti-rat IL-1β (AF-501-NA; R&D Systems, Inc., Minneapolis, MN, USA) The HMGB1 antibody was used at a final concentration of μg/ml, and ... and Analytical Sciences, Inc., Waltham, MA, USA) at the 3' end by means of terminal deoxynucleotidyltransferase (Amersham, now part of GE Healthcare, Little Chalfont, Buckinghamshire, UK) and...
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Báo cáo y học: "Treatment of stasis dermatitis using aminaphtone: Development of Buffalo Hump in the course of antiretroviral therapy including raltegravir and unboosted atazanavir: a case report and review of the literature" pot
... disorder and could constitute a background that contributes to the final appearance of buffalo hump after raltegravir plus atazanavir treatment Current data indicate that the etiology of HIV-associated ... to stavudine, lamivudine and nevirapine because of an episode of acute renal colic Our patient attended outpatient clinics on a regular basis, and was found to have a good immunological and virological ... the literature available to date regarding such a combination There are no publications today that describe a relationship between RAL and unboosted ATV therapy and the occurrence of Buffalo Hump...
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Báo cáo khoa hoc:" Prospective Epidemiological Observations on the Course of the Disease in Fibromyalgia Patients" doc
... about marital status, educational background, general state of health, functional and vegetative symptoms, anamnesis regarding pain of the locomotor system, pain behavior, functional disturbances ... disturbances in relation to the time of day and stress and activity Factors that are intrinsically associated with the disease, such as medication, satisfaction with life (visual analogue scale from 0–10; ... this same questionnaire again, together with a further questionnaire enquiring about treatments, clinical examinations, methods of treatment, inpatient treatment, planned treatment strategies, and...
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Báo cáo y học: " Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population" ppt
... eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid d Sum of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid and α-linolenic acid e Sum of arachidonic ... docosahexaenoic acid (DHA) and docosapentaenoic acid d Adjusted for age, total energy intake and dietary intake of vitamin B12, alcohol and dietary intake of fat other than eicosapentaenoic acid, ... importance A high intake ratio of omega-3:omega-6 fatty acids favor omega-3 fatty acid metabolism For example, high intake of omega-3 fatty acids partly replaces omega-6 fatty acids incorporation...
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Báo cáo y học: "The course of untreated anxiety and depression, and determinants of poor one-year outcome: a one-year cohort study" ppt
... specifically been validated, a study comparing PNCQ data from an Australian and a Dutch sample of primary care patients with anxiety and/or depression, showed many similarities between the given answers ... http://www.biomedcentral.com/1471-244X/10/86 Page of 10 Table Potential risk factors of a poor outcome in anxiety at T1: multilevel univariate and multivariate linear regression analyses Univariate Multivariate b SE Variance at GP-level ... our study employed observational data No conclusions about a causal relationship between care utilization and clinical outcome can therefore be drawn Our data are not suitable for determining the...
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Báo cáo y học: "Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different SOFA scores during the course of sepsis and MODS" pot
... observations CRP, C-reactive peptide; APACHE, Acute Physiology, Age, Chronic Health Evaluation Figure m, Males; f, female; SOFA, sepsis-related organ failure assessment; APACHE, Acute Physiology, Age, ... Critical Care 1999, Vol No Table The sepsis-related organ failure assessment (SOFA) score evaluation system of multiple organ dysfunction [12] Six organ systems are evaluated as a scale of 1–4 each ... however, analyzed the severity of multiple organ dysfunction rather than the severity of sepsis and systemic inflammation and there are no data available as to the relation of PCT concentrations and...
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Báo cáo y học: "Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D" pps
... coccidioidal antigens, SP -A and SP-D antigens and antibodies This work is supported by research grants from San Antonio Area Foundation from Semp Russ Foundation, and California Health Care Foundation, ... approved the final manuscript Acknowledgements Authors acknowledge the technical assistance of Adrian Donias and Amy Chein in animal studies We also thank Dr Rebecca A Cox (UTHSCSA, San Antonio, TX), ... designed and co-ordinated the study, performed assays and statistical analysis and drafted the manuscript JJC assessed lung pathology DMM prepared and immunized mice with FKS All authors read and approved...
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Báo cáo y học: "Prior mucosal exposure to heterologous cells alters the pathogenesis of cell-associated mucosal feline immunodeficiency virus challenge" docx
... FIV-gag was amplified from 150 ng of each sample with primers GagNCSU1-1247 sense (5'-GCTTAAAGCAATTGACGGCAGAGTATGATCG-3') and GagNCSU1-1417 anti-sense (5'-CCTCGAGATACCATGCTCTACACTGCATCC-3') as ... Laboratories) SPF cats were obtained, housed, acclimated, and cared for in accordance with the standards of the American Association of Accreditation of Laboratory Animal Care and The Ohio State ... pre/Ave background CPM at pre) × 100 Pre exposure data was normalized to 100% for each animal and data presented as change from baseline ELISA Serum antibody against FIV p24Gag was detected by adding...
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Báo cáo y học: " Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts" pdf
... Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, et al.: A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis ... were measured on day after diagnosis of ventilator-associated pneumonia in Group II Values are shown as median +/- 95% confidence interval (CI) and as mean +/- standard error Number of patients ... Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland...
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Báo cáo y học: "Soluble triggering receptor on myeloid cells-1 is expressed in the course of non-infectious inflammation after traumatic lung contusion: a prospective cohort study" pptx
... in bacterial infection: a meta-analysis Intensive Care Med 2009, 35:587-595 Porfyridis I, Plachouras D, Karagianni V, Kotanidou A, Papiris SA, Giamarellou H, Giamarellos-Bourboulis EJ: Diagnostic ... range Normally distributed values are presented as the mean ± standard deviation A two-tailed P value < 0.05 was considered statistically significant A correlation between sTREM-1 and the paO2/FiO2 ... study was approved by the local ethics committee (Ethik-Kommission, Johann Wolfgang Goethe-Universität Frankfurt am Main) Clinical treatment and data sampling Following initial trauma care and surgical...
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báo cáo khoa học: " Recent advances in the genetics of language impairment" docx
... 49 Yamakawa H, Oyama S, Mitsuhashi H, Sasagawa N, Uchino S, Kohsaka S, Ishiura S: Neuroligins and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations ... Watkins KE, Vargha-Khadem F, Gadian DG: Bilateral brain abnormalities associated with dominantly inherited verbal and orofacial dyspraxia Hum Brain Mapp 2003, 18:194-200 36 Liégeois F, Baldeweg T, ... development of human language [79] Characterization of these pathways and the way they overlap and interact will be an enormous task but one that is becoming increasingly feasible thanks to advances in...
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Báo cáo khoa học: Mechanism of the ring contraction process in vitamin B12 biosynthesis by the anaerobe Propionibacterium shermanii under aerobic conditions docx
... functionalities in precorrin-3x J Am Chem Soc 116, 4991–4992 11 Kurumaya K, Okazaki T, Seido N, Akasaka Y, Kawajiri Y, Kajiwara M & Kondo M (1989) A facile synthesis of d-aminolevulinic acid (ALA) ... spectrometer (Jasco Corp., Tokyo, Japan) The air pump was a Nisso INNOb4000 (Nisso Co., Saitama, Japan) Aerobic or anaerobic feeding experiments with [1-13C]ALA and [1-13C,1,1,4-18O3]ALA in P shermanii ... purchased from Cambridge Isotope Laboratories (Andover, MA, USA) [1-13C,1,1,4-18O3]ALA was synthesized by heating [1-13C]ALA with [18O]water (95–98 atom % 18O; purchased from Cambridge Isotope Laboratories)...
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