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Standard Form of Agreement for Design Services potx

Standard Form of Agreement for Design Services potx

Ngày tải lên : 23/03/2014, 22:20
... accordance with the laws of the United States and the state of _ without regard to its conflict of law provisions or the conflict of law provisions of any other jurisdiction In the event of a dispute ... together and signed, the custom proposal document and its attached terms and conditions comprise the binding agreement with the client With this in mind, the new focus of the AIGA Standard Form of ... REGARDLESS OF THE FORM OF ACTION, WHETHER IN CONTRACT, TORT OR OTHERWISE, SHALL BE LIMITED TO THE NET PROFIT OF DESIGNER IN NO EVENT SHALL DESIGNER BE LIABLE FOR ANY LOST DATA OR CONTENT, LOST PROFITS,...
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Tài liệu Supply the correct form of the verbs1 docx

Tài liệu Supply the correct form of the verbs1 docx

Ngày tải lên : 23/01/2014, 07:20
... a snake.were / wouldn't want 14 My brother managed to kill the snake just at the time when I (be) almost exhausted If he (be) a little late, I (kill) by the snake.was / had been / would have ... a snake 14 My brother managed to kill the snake just at the time when I (be) had been almost exhausted If he (be) had been a little late, I (kill) would have been killed by the snake 15 Had I ... in a snake 14 My brother managed to kill the snake just at the time when I were almost exhausted If he had beena little late, I would have killed by the snake 15 Had I know you were ill, I (visit)would...
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Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

Ngày tải lên : 18/02/2014, 06:20
... Furthermore, the pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16] In the case of BMP-9, the pro-peptide appears not to alter significantly the activity of the ... interested in the role of the 263 amino acid pro-peptide of BMP-2, because evidence accumulated over recent years has shown that the pro-forms of growth factors can modulate the activities of the mature ... patients [39], and a role of the receptor in the development of the arthritis has been discussed [26] The data presented here provide clear evidence that the pro -form of BMP-2 can interact with...
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Tài liệu Báo cáo khoa học: Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme ppt

Tài liệu Báo cáo khoa học: Regulation of dCTP deaminase from Escherichia coli by nonallosteric dTTP binding to an inactive form of the enzyme ppt

Ngày tải lên : 18/02/2014, 16:20
... in the main chain of the subunit, or in the interaction of subunits within the trimer that linked the conformation of residues 120–125 to the position of the active site lip and closure of the ... site lip prevented binding of the C-terminal residues over the active site, or the absence of the C-terminal residues caused the movement of the lip (Fig 1B) In addition, the Ca chain between amino ... the dTTP complex to accommodate the 5-methyl group of the thymine moiety As a result, the Ala124 carbonyl was moved from the 4-oxo ⁄ 4-amino group of the bound nucleotide and the side chain of...
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Tài liệu The 2012 Nexus Event – An Unknown Form Of Energy Is Coming Our Way pdf

Tài liệu The 2012 Nexus Event – An Unknown Form Of Energy Is Coming Our Way pdf

Ngày tải lên : 19/02/2014, 03:20
... to the ancient people Besides that, we hear about the hidden Astrology and the various aspects of the 12 signs of Zodiac, than about the effect which comes from the alignment of the Pole of our ... equator and the alignment of Earth with the center of the Milky Way This Cosmic Cross is considered as embodiment of the Sacred Tree, (The Tree of Life), a tree which is remembered in most of the ancient ... 28 March 2013 when in fact is the end of the Sun-Venus calendar and in the same time the start of Sixth Sun During this process from the direction of the center of the Milky Way a cosmic rays will...
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Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

Ngày tải lên : 19/02/2014, 06:20
... Although the SH3 domain of Noxo1 participates in regulation of Nox3, the role of the PX domain in Nox3 activity remains unknown In the process of cloning of human Noxo1, some spliced transcripts of the ... between the pair of primers (Fig 2A) The lengths of the PCR products of Noxo1b and Noxo1c were 225 and 240 bp, respectively To delineate the difference in the two products, we subjected the PCR ... To compare the amounts of the two variants expressed in the testis, we performed the PCR using the primers ‘d’ and ‘c’, where the cDNAs for both Noxo1b and Noxo1c are amplified as the insert region...
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Báo cáo khoa học: Crystal structures of the apo form of b-fructofuranosidase from Bifidobacterium longum and its complex with fructose pot

Báo cáo khoa học: Crystal structures of the apo form of b-fructofuranosidase from Bifidobacterium longum and its complex with fructose pot

Ngày tải lên : 06/03/2014, 00:21
... In the first step of the enzymatic reaction, a nucleophilic attack is performed on the anomeric carbon of the sugar substrate by the carboxylate of the Asp54 acting as the primary nucleophile, forming ... anomeric carbon of fructose The leaving group is carboxylate of Asp54 Dimerization The asymmetric units of the crystals of both the apo and complexed form of the enzyme consist of dimers with ... respectively The results of MS of recombinant b-fructofuranosidase are close to the theoretical value of the molecular mass A peak of molecular ion at m ⁄ z = 58 879 Da was observed on the MALDITOF mass...
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Báo cáo khoa học: DNA polymerase e associates with the elongating form of RNA polymerase II and nascent transcripts pot

Báo cáo khoa học: DNA polymerase e associates with the elongating form of RNA polymerase II and nascent transcripts pot

Ngày tải lên : 07/03/2014, 11:20
... coprecipitated only the slowly migrating form of RNA pol II (Fig 1) This suggested that Pol e associates with the RNA pol IIO isoform To characterize further the phosphorylation status of the RNA pol ... isoform IIO that exhibits reduced electrophoretic mobility compared with the IIA isoform Whereas the polyclonal antiRNA pol II antibody precipitated both the fast and slowly migrating forms of ... Following phosphatase treatment, the cellular fraction of RNA pol II that associated with Pol e showed increased mobility, corresponding to that of isoform IIA The isoform IIO was also lost from RNA...
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Báo cáo khoa học: Purification and structural study of the b form of human cAMP-dependent protein kinase inhibitor pdf

Báo cáo khoa học: Purification and structural study of the b form of human cAMP-dependent protein kinase inhibitor pdf

Ngày tải lên : 07/03/2014, 15:20
... regulation of the PKI and PKI isoforms of the inhibitor protein of the cAMP-dependent protein kinase J Biol Chem 272, 20011–20020 Byler, D.M & Susi, H (1986) Examination of the secondary structure of ... for further study The concentration of the proteins was determined by the method of Lowry et al [14] and the purity was examined by SDS/PAGE [15] Assay of human PKIb activity The activity of purified ... Characterization of PKI gamma, a novel isoform of the protein kinase inhibitor of cAMPdependent protein kinase J Biol Chem 272, 18169–18178 Gamm, D.M & Uhler, M.D (1995) Isoform-specific differences in the...
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INTERNATIONAL STANDARD Microbiology of food and animal feeding stuffs — Horizontal method for the detection of Salmonella spp docx

INTERNATIONAL STANDARD Microbiology of food and animal feeding stuffs — Horizontal method for the detection of Salmonella spp docx

Ngày tải lên : 07/03/2014, 16:20
... approval by at least 75 % of the member bodies casting a vote Attention is drawn to the possibility that some of the elements of this International Standard may be the subject of patent rights ISO ... International Standard are encouraged to investigate the possibility of applying the most recent editions of the normative documents indicated below For undated references, the latest edition of the normative ... examine the plates (9.4.3) for the presence of typical colonies of Salmonella and atypical colonies that may be Salmonella (see Note) Mark their position on the bottom of the dish Typical colonies of...
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Báo cáo khoa học: The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure pot

Báo cáo khoa học: The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure pot

Ngày tải lên : 07/03/2014, 21:20
... that of its unglycosylated form, though the DV and DGP values were almost the same The Pm value of proCPY was higher than that of its unglycosylated form This is due to the higher DV value of the ... that the precursor form was less thermally stable than the mature form, regardless of the carbohydrate moiety After the temperature was lowered from the highest temperature tested to 25 °C, the ... (Fig 1A), indicating that the thermal unfolding process of the precursor form follows a two-state transition The ratio of the unfolding enthalpy (DHcal) to the van’t Hoff enthalpy (DHv) was 1.05...
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Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx

Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx

Ngày tải lên : 16/03/2014, 10:20
... between the two proteins (as indicated by the values of DGwater, Cm and Tg) hence arise from the changes in the surface of the protein because of the interactions of the cofactor with the protein ... are comparable, the Tg values of the proteins vary slightly; there is a difference of almost C between the Tg values of the proteins, the value being higher for the holo form There have been ... in the range 15) 60 C The results of the analysis of these curves using the linear extrapolation model (LEM) are shown in Tables and and Fig 4AC There is a slight temperature dependence of the...
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Báo cáo khoa học: The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of b-glucosidase docx

Báo cáo khoa học: The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of b-glucosidase docx

Ngày tải lên : 22/03/2014, 21:20
... long half-life of the enzyme The inability to detect IFG in the brain of L444P GCase mice is most probably a result of the dose of IFG tartrate administered (20 mgÆkg)1Æday)1) and the relatively ... 499.6 for the C16:0 D3 inter- 1634 R Khanna et al nal standard For quantification, the area counts for each isoform were determined and summed to obtain the total GC area counts The ratio of the total ... stress, which, in turn, could affect the organ weights and plasma marker levels of these animals Whether the effects of IFG on the organ weights and plasma markers of inflammation in L444P GCase mice...
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Báo cáo khoa học: Common mode of DNA binding to cold shock domains Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus pot

Báo cáo khoa học: Common mode of DNA binding to cold shock domains Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus pot

Ngày tải lên : 23/03/2014, 09:21
... allowing them to re-associate as domain-swapped dimers Apart from differences in the course of the protein backbone at the point of transition, in the swapped dimer the overall structure of the functional ... with the nucleobases pointing towards the protein surface The 5¢-to-3¢ polarity of the ligand follows that of most other nucleic acid complexes of OB-fold proteins, starting in the vicinity of ... shields the hydrophobic nucleobases and the hydrophobic-binding platform of the protein below them from the polar solvent (Fig 2B) The sugar of T1 from chain C maintains a C4¢-exo pucker, whereas the...
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Báo cáo khoa học: Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4 doc

Báo cáo khoa học: Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4 doc

Ngày tải lên : 23/03/2014, 15:21
... structure of the soluble form of CLIC4 the backbone and side chain of Asn34 and the side chain of Lys24 This crystal contact stabilizes the structure of the leading side of the foot loop The putative ... the side chain of Asn81 The intervening residues of the C-terminal extension interact with the neighboring monomer via hydrophobic contacts Comparison with the structure of the soluble form of ... C-terminus, while Arg206 is on the top of the molecule, in the loop leaving helix and it points in the opposite direction to the other basic residues (Fig 2B) The structure of the NLS is almost identical...
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Báo cáo Y học: The presence of phosphate at a catalytic site suppresses the formation of the MgADP-inhibited form of F1-ATPase potx

Báo cáo Y học: The presence of phosphate at a catalytic site suppresses the formation of the MgADP-inhibited form of F1-ATPase potx

Ngày tải lên : 24/03/2014, 00:21
... observed in the presence of Pi [18] Here we examined the effects of Pi on the formation of the MgADPinhibited form of the a(W463F)3b(Y341W)3c subcomplex The extent of ADP inhibition of the a(W463F)3b(Y341W)3c ... addition of a3b3c to 1.2 mL of the assay mixture One unit (U) of activity is de®ned as the activity of lmol ATP hydrolysedámin)1 The ATPase activities at the initial phase (the slope of A340 between ... concentrations of MgADP plus various concentrations of potassium phosphate was measured Increasing concentrations of Pi prevented the formation of the MgADP-inhibited form of the a(W463F)3b(Y341W)3c...
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Báo cáo khoa học: "TWO THEORIES FOR COMPUTING THE LOGICAL FORM OF MASS EXPRESSIONS" doc

Báo cáo khoa học: "TWO THEORIES FOR COMPUTING THE LOGICAL FORM OF MASS EXPRESSIONS" doc

Ngày tải lên : 24/03/2014, 01:21
... (Note also the comprehensive denotation of edible) No other theory we know of can account for the validity of these two arguments Both of these theories take it that is wine is true of the (abstract) ... assigning the same logical form to both theories Nonetheless, the meaning postulates of the two theories will differ for these.) In addition to the sorts of examples stated above, both these theories ... true of unions of elements of the semilattice) These predicates are not only true of the conventional kinds but also of conventional servings such as the bottle of wine on the table or the 250ml...
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