fertility teratogenicity and in utero effects on the fetus

Báo cáo y học: " Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements" pot

Ngày tải lên : 13/08/2014, 05:21

... proteins on bona fide exogenous retroviruses on the one hand and intracellular retroelements on the other Results and discussion Restriction of murine and human infectious ERVs by APOBEC3 proteins ... simply to be the consequence of the restriction that initially controlled the progenitor infectious IAPE invading the rodent ancestor, with the effect being maintained in the evolution of the endogenized ... trinucleotide motifs [26,31,33] On the other hand, the G-to-A substitutions in the HERV-K copies are most frequently observed in the GG context (see arrow in Figure 3B), which corresponds to the...

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Age- and sex-related effects on the neuroanatomy of healthy elderly pdf

Ngày tải lên : 05/03/2014, 21:20

... effect on brain atrophy on the same sample, what seems contradictory with their findings concerning the CSF and may indicate a problem in volume estimation that could possibly originate from the ... high in the angular and superior parietal gyri, in the orbital part of the prefrontal cortex, and in the hippocampal region By contrast, the rate of GM losses appeared marginal in areas such as the ... decrease of GM in healthy elderly Note that this area has been reported in functional neuroimaging studies as mainly involved in maintaining information in working memory (see Tisserand and Jolles,...

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Globalization and its effects on the development of educational service in Vietnam

Ngày tải lên : 23/04/2013, 11:16

... education and training We will distinguish between schooling, vocational training and tertiary education (UNESCO, 2003) in the national context, and foreign education in the international context: ... requiring further training Thus, continued participation in export markets requires continuous skill upgrading through training There is also increasing interest in the impact of global value chains ... institutes often supply the training program for local workers in international standards In conclusion, the increase in FDI into Vietnam not only increases the demand for quantity but also increases...

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Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx

Ngày tải lên : 16/03/2014, 01:20

... ATP-binding domain of HSP70 is essential for the inhibition of H2O2-induced activation of caspases-9 and -3 and apoptosis (A) The effects of HSP70 and its deletion mutant proteins on the activation ... ATPbinding domain, the peptide-binding domain, and the EEVD motif Although the EEVD motif is considered to be involved in the chaperone function of HSP70, and was assumed to mediate cytoprotection ... signalregulating kinase (ASK1) and the inhibition of ASK1-induced apoptosis in vitro [28] Furthermore, the ATP-binding domain of HSP70 is critical for sequestering AIF in the cytosol [29] In the present...

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Báo cáo y học: " Effects of carbohydrate, branched-chain amino acids, and arginine in recovery period on the subsequent performance in wrestlers" potx

Ngày tải lên : 11/08/2014, 23:21

... BCAA and arginine during the post-match period had no effect on the performance in the following simulated match in wrestlers In addition, BCAA and arginine did not provide additional insulinemic ... insulin-dependent phase by inducing insulin secretion [14, 15] The consumption of leucine and arginine along with glucose could result in higher insulinemic response compared to glucose alone in healthy subjects ... between the CHO and CHO+AA trial in either glucose or insulin concentration at any time point The AUC of plasma glucose and insulin concentrations were also similar between the 13 CHO and CHO+AA...

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Báo cáo y học: "Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis" doc

Ngày tải lên : 12/08/2014, 11:23

... molecules candidate mediators of T-cell inhibition The involvement of iNOS and COX-2 in inhibition of T-cell proliferation was demonstrated by the addition of inhibitors of these enzymes - GW274150 and ... for these two T-cell inhibitors in T-cell proliferation inhibition In addition, we could demonstrate that IL-17, in synergy with IFN-g, can induce the expression of iNOS, COX-2, and PD-L1 in MSCs ... and indomethacin [8,36], respectively - to the co-cultures The addition of these inhibitors resulted in the abrogation of the inhibition of Tcell proliferation by wild-type MSCs (Figure 3e) The...

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Báo cáo y học: "Survivors of war in the Northern Kosovo (II): baseline clinical and functional assessment and lasting effects on the health of a vulnerable population" ppsx

Ngày tải lên : 13/08/2014, 14:20

... difference in the strength of dominant and nondominant hands was less in victims Five victims had no strength in either hand; two had no strength in the right hand, and one had none in the left hand Only ... personal information and elicit trauma experience Information on physical functioning and activity, participation in social life and environmental factors was obtained in further interviews using ... to record the location, following the guidelines of the Istanbul Protocol: the UN manual on the effective investigation and documentation of torture and other cruel, inhuman or degrading treatment...

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The analysis of theme and rheme in little house on the prairie = sự phân tích về đề ngữ và thuyết ngữ, thông qua truyện ngôi nhà nhỏ trên thảo nguyên

Ngày tải lên : 22/12/2013, 12:59

... Interpersonal Themes, on the other hand, reveal something of the attitude of the speaker or the writer And Textual Theme is the link between the clause contains that Theme and the rest of the discourse ... position in the clause But the initial position, that it is the first constituent that constitutes the Theme, has now been made more obvious for understanding: the Theme extends from the beginning ... Theme can be identified according to the theory of functional linguistics: topical, Interpersonal, and textual Topical Themes have to with the information conveyed in the discourse Interpersonal...

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Tài liệu Báo cáo khóa học: Trichostatin A reduces hormone-induced transcription of the MMTV promoter and has pleiotropic effects on its chromatin structure pptx

Ngày tải lên : 19/02/2014, 12:20

... translational positioning being induced by TSA Our observations suggest that nucleosome repositioning during hormone induction [6] is not solely explained by GR binding to the GRE sequences within the ... methylation assay in the MMTV promoter in the noninduced state Addition of hormone resulted in a drastic reduction in DMS methylation (protection) over the glucocorticoid response elements In agreement ... method allows easy detection of DNA–protein interactions via the N7 position of guanines in the major groove and via the N3 position of adenines in the minor groove The DMS cleavage pattern was...

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Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf

Ngày tải lên : 07/03/2014, 03:20

... ´ and Sigma (Poznan, Poland) Construction of fusion proteins The human dopamine D1 and D2 receptor genes were cloned into the pcDNA3.1(+) plasmid and used as the starting point to construct the ... subunit of the G protein and not in the other case Although there is discussion in the literature concerning the possibilities of photoconversion of YFP into a CFP-like species during acceptor ... D2R2, D2R3) These experiments were performed to determine the in uence of the introduced mutations on the localization of the receptor proteins and the degree of their colocalization Figure 2A,B...

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Báo cáo khoa học: Spectroscopic and kinetic properties of the horseradish peroxidase mutant T171S Evidence for selective effects on the reduced state of the enzyme potx

Ngày tải lên : 07/03/2014, 21:20

... demonstrated the sensitivity of the proximal region in determining the electronic and structural properties of the haem pocket In the present study we attempt to obtain further insights into the ... of the porphyrin ring itself together with the bending modes of the propionyl and vinyl substituents of the haem Class III peroxidases normally exhibit only one Fe-Im band, in contrast to the ... by the Thr171Ser mutation was obtained from comparison of the electronic absorption and RR spectra of the wild type and Thr171Ser either in the presence of the aromatic donor BHA or at alkaline...

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Dry mouth and its effects on the oral health of elderly people pptx

Ngày tải lên : 14/03/2014, 20:20

... functions in the oral and gastrointestinal environment Saliva aids in swallowing, oral cleansing, speech, digestion and taste When salivary hypofunction and xerostomia occur, transient and permanent ... dehytion of the serous-producing salivary cells occurs dration), medications (both prescription and nonvia a process termed “apoptosis.” Within one week prescription), head and neck irradiation and ... accompanying infection A swollen parotid gland can displace the earlobe and extend inferiorly over the angle of the mandible, whereas an enlarged submandibular gland is palpated medial to the posteroinferior...

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Investigation of au and in as solvents for the growth of silicon nanowires on si(1 1 1)

Ngày tải lên : 16/03/2014, 15:17

... formation between indium and gold, we will consider in the following the effects of different diffusion coefﬁcients of gold and indium on silicon, the solubility of substrate atoms in the two ... Fig Binary phase diagrams; top: In Si and bottom: Au–Si Since the state of the substrate surface after desorption and the vacuum conditions are the same during evaporation of gold and indium, the ... surface The size and distribution of gold and indium droplets on the silicon surface that we observed by SEM and TEM after cooling down (Figs 1–3) may be therefore reasonably explained considering the...

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thermal treatment effects on the material and gas-sensing properties of room-temperaturetungstenoxidenanorodsensors

Ngày tải lên : 20/03/2014, 13:11

... relative intensity is very similar On the other hand, the intensity distribution of the diffraction peaks in the range of 32–35◦ can provide a clue to distinguish between triclinic and monoclinic ... corresponding to W6+ and W5+ oxidation states Table summarizes the parameters used in the deconvolution of W 4f XPS peaks, i.e the binding energy of the W 4f7/2 , FWHM and relative contribution of the ... conﬁrmed to exist within the ﬁlm probably due to the incorporation of carbon atoms originated from carbon-containing chemicals used in the synthesis processes, together with a considerable amount...

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Marijuana Effects on the Endocrine and Reproductive Systems pptx

Ngày tải lên : 22/03/2014, 12:20

... structures and biochemical processes starting in the nucleus with DNA and terminating with the RNA molecule Dr Stein then reviewed his studies on the effect of cannabinoids on the genome, and on gene ... modifications in cellular function Since cannabinoid-induced alterations in gene expression can result from changes in the organization of genetic sequences and/ or in the manner in which genetic information ... Marijuana Effects on the Endocrine and Reproductive Systems ACKNOWLEDGMENT This monograph is based upon papers and discussion from the RAUS Review Conference on the Endocrine and Reproductive Effects...

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Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf

Ngày tải lên : 23/03/2014, 21:21

... Inuence of the NaCl on TOP and neurolysin activities The inuence of NaCl concentration on kcat/Km values of TOP and neurolysin activities on the peptides containing Ala, Val, Asp and Ile at the ... neurolysin with the substrate containing Val On the other hand, deviations from the linearity were observed in the experiments with TOP above 25 C (Fig 1), and breaks in the plots were veried in the ... shielding of charges present in the enzymes and in the substrates, as suggested the results obtained with the peptide containing X ẳ Asp (Table 4) Finally the activation of TOP and neurolysin by increasing...

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Impacts of nutrition and human services interventions on the health of elderly and disabled persons in public housing docx

Ngày tải lên : 28/03/2014, 17:20

... having the condition Heart disease, hypertension, or stroke (40% and 35%) and trouble seeing (34% and 38%) are the second most reported conditions among the treatment and control groups We find ... treatment for their chronic conditions Cost is the most commonly cited barrier to obtaining healthy foods One-fifth of people in the treatment and control groups report shrinking portion sizes and/ or ... Services The concept of linking housing and supportive services is not new In establishing the Congregate Housing Services Program (CHSP) in 1978, the US Congress noted that “congregate housing,...

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Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Ngày tải lên : 31/03/2014, 08:20

... CNX and CRT than with BiP Effects of interactions between TSHR and CNX and CRT We then attempted to determine the effects of these interactions on the maturation of the receptor CNX is an integral ... TSHR (Fig 4) The association with CNX and/ or CRT therefore seems contribute to the stability and/ or the maturation of the TSHR To obtain further insights into the contribution of CNX and CRT to ... vasopressin receptor and gonadotropin receptor), interactions have been found to occur with various molecular chaperones, but the effects of these interactions on the maturation of these receptors...

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Báo cáo hóa học: "The impact of psychosocial and organizational working conditions on the mental health of female cleaning personnel in Norway" doc

Ngày tải lên : 20/06/2014, 00:20

... factors: Working alone /in a pair /in a team Working alone Working in a pair Working in a team Missing Total Contact with colleagues at the workplace Every day Every week/minimum once a month More ... seeking professional help, taking medication, and change in functioning [29] Twentyfive questions, which measure the frequency and intensity of symptoms during the past week, are scored on a ... of control over working conditions, and a lack of promotional prospects [13,25-27] Nevertheless, most existing studies have focused narrowly on the ergonomic and chemical hazards of the cleaning...

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Báo cáo hóa học: " Size and temperature effects on the viscosity of water inside carbon nanotubes" pptx

Ngày tải lên : 21/06/2014, 06:20

... all the computational consumption on the concerned information Results and discussion Figure shows the relative viscosity of water confined in SWCNTs versus the diameter at 298, 325, and 350 K The ... of the hydrogen bonds of water confined in SWCNTs with the diameter The relative amount is the ratio of the amount of the hydrogen bonds of the confined water to the amount in the bulk water In ... and 325 K These increments in the transition region can be ascribed to the structural configuration of the water molecules inside the (8, 8) and (9, 9) SWCNTs Figure presents the configurations...

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