... theoretical or geometric stress- concentration factor for determination of the true state of stress in the vicinity of stress raisers. THEORETICAL (GEOMETRIC) STRESS- CONCENTRATION FACTOR, t K AND ... “actual” stress resulting from a geometric stress raiser, a theoretical stress- concentration factor is applied to the nominal stress. For a part subjected to a normal stress, the true stress ... Theoretical stress- concentration factor Nominal normal stress t K σ = = Similarly, we can also estimate the highly localized amplification of shear stress in the vicinity of a geometric stress concentration, ...
Ngày tải lên: 27/01/2014, 05:20
... Helicobacter pylori acidic stress response factor HP1286 is a YceI homolog with new binding specificity Lorenza Sisinni 1,2 , Laura ... stomach. Indeed, it was demonstrated to be overexpressed under acidic stress conditions, together with other essential virulence factors. Here we describe its crystal structure, determined at 2.1 ... in human neutrophils. Eur J Immunol 33, 840–849. L. Sisinni et al. Structure of acidic stress response factor HP1286 FEBS Journal 277 (2010) 18961905 ê 2010 The Authors Journal compilation ê...
Ngày tải lên: 16/02/2014, 14:20
stress concentration
... strain concentration factor K f Effective stress concentration factor for cyclic loading, fatigue notch factor K i Effective stress concentration factor for impact loads K σ Effective stress concentration ... −0.600h/r TABLE 6-1 Stress Concentration Factors 299 CHAPTER 6 Stress Concentration 6.1 Notation 255 6.2 Stress Concentration Factors 256 6.3 Effective Stress Concentration Factors 259 Neuber’s ... in stress near a stress raiser, the stress concentration factor or theoretical stress concentration factor is defined as the ratio of the calculated peak stress to the nominal stress that would...
Ngày tải lên: 24/05/2014, 20:37
analysis and determination of the stress intensity factor of load-carrying cruciform fillet welded joints
... final crack propagation. 6.1.3 Calculation of the Stress Intensity Factors. When a propagating crack is considered, the stress intensity factors and crack growth direction must be calculated ... welded joints, stress concentrations occur at the weld toe or at the weld root, which make these regions the points from which cracks may initiate. The values of stress intensity factor (K I ) ... or cold lab crack) on the stress intensity factor (K I ) under a constant load. The applied edge stress for the model was based on the development of the yield stress over the net cross-section....
Ngày tải lên: 24/05/2014, 20:40
finite element simulation and analysis of local stress concentration in polymers with a nonlinear viscoelastic constitutive model
Ngày tải lên: 29/11/2014, 07:00
Tài liệu Báo cáo khoa học: The heat shock factor family and adaptation to proteotoxic stress pdf
... protection against proteotoxic stress, including heat shock and oxidative stress. In Escheri- chia coli, heat shock genes are under the control of a specific transcription factor, r32, which directs ... shock factor function and regulation in response to cellular stress, growth, and differentiation signals. Gene Expr 7, 271– 282. 8 Nakai A (1999) New aspects in the vertebrate heat shock factor ... & Sistonen L (2007) Heat shock factors at a crossroad between stress and development. Ann NY Acad Sci 1113, 15–27. 13 Nakai A (2009) Heat shock transcription factors and sensory placode development....
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: A genetic screen identifies mutations in the yeastWAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation docx
... that weak-acid stress response requires two major components, a dedicated stress regulator and the Pdr12p efflux pump. The defective War1-42 p mutant is no longer phosphorylated upon stress and C. ... colonies were re-screened for their Pdr12p protein concentrations by immuno- blotting. Although several mutants showed reduced Pdr12p concentrations under stress conditions (data not shown), only two ... are phosphorylated upon stress, although they are already active in the absence of sorbate stress (Fig. 4A). Therefore, in constitutively active War1p variants, sorbate stress is tightly linked to...
Ngày tải lên: 19/02/2014, 00:20
THE MECHANISMS REGULATING THE TRANSCRIPTION FACTOR ATF5 AND ITS FUNCTION IN THE INTEGRATED STRESS RESPONSE
Ngày tải lên: 24/08/2014, 11:17
Phân tích nhân tố khám phá (Exploratory Factor Analysis) bằng SPSS
... quan sát var i có factor loading lớn nhất nằm tại cột nào thì biến quan sát var i thuộc về nhân tố đó. Biến gss7 có factor loading lớn nhất bằng 0.769 và biến gss8 có factor loading lớn nhất ... International, Inc, Factor loading là chỉ tiêu để đảm bảo mức ý nghĩa thiết thực của EFA (ensuring practical significance). Factor loading > 0.3 được xem là đạt được mức tối thiểu, Factor loading ... chuẩn factor loading > 0.3 thì cỡ mẫu của bạn ít nhất phải là 350, nếu cỡ mẫu của bạn khoảng 100 thì nên chọn tiêu chuẩn factor loading > 0.55, nếu cỡ mẫu của bạn khoảng 50 thì Factor...
Ngày tải lên: 24/10/2012, 09:05
Báo cáo y học: "Influence of Cyclodextrin Complexation with NSAIDs on NSAID/Cold Stress-Induced Gastric Ulceration in Rats"
... experiencing restraint and cold stress alone (X200); B: from rats experiencing restraint and cold stress, and treated with β-CD; C: from rats experiencing restraint and cold stress, and treated with ... protective agents against ga- strointestinal disorders initiated by restraint and cold stress, or by restraint and cold stress and the co-administration of either indomethacin or pirox- icam. Consequently, ... of effect on stress- ulceration. J Pharmacol Exp Ther. 1989; 251: 435-8. 4. Savran B, Görgün CZ, Zengil H. Circadian reactivity rhythm of rat gastric mucosa to restraint-cold stress and indomethacin:...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"
... synthesis was increased by oxidative stress (55). From our study, the increased concentration of TBARS and decreased concentration of TAS supports the oxidative stress in anoxia. In this study ... leading to neuronal damage in anoxia. The increased concentration of TBARS and decreased concentration of TAS supports the oxida- tive stress in anoxia and reperfusion and suggests a possible ... (11-12), through activation of the JNK pathway (13) or by activation of nuclear factor- K B (NF- K B) transcription factors (14). The ability to control ROS is thus critical in neurodegenerative...
Ngày tải lên: 26/10/2012, 09:07
Báo cáo y học: "Serum cholesterol concentration associated with aspirin esterase activity in older people: preliminary data"
... activity levels were correlated signif- icantly and positively with those of total cholesterol concentrations (Table 1). Moreover, both variables showed a significantly and independently positive ... 0.05. DISCUSSION The present study’s main finding is that the changes in serum total cholesterol concentrations are clearly associated with those of aspirin esterase activ- ity during a period ... be elucidated, our data showing its significant correlations with the changes in cholesterol concentrations may open new avenues for exploration of aspirin metabolism. Our present results...
Ngày tải lên: 26/10/2012, 09:39