family caregivers and members of the community

... and -D, structure and function L J Reigstad et al endothelial growth factors (VEGF) and the family is therefore often referred to as the PDGF ⁄ VEGF family The PDGF family of growth factors The ... perivascular lymphoid cell infiltrates of the lung and fibrosis in the liver [110] Conclusions The novel members, PDGF-C and -D, of the PDGF subfamily of the cystine knot family of growth factors are potent ... removal of the CUB domains and thereby activation of the growth factor domains PDGF-C and -D contain both the CUB and growth factor domains when they are secreted and proteolytic cleavage is therefore...

Ngày tải lên: 19/02/2014, 07:20

... illustrating the arrangement of all domains in the five-domain members of the GH 13, can be taken as an approximation of the first three domains in the four-domain members It also shows the typical ... cluster of Bacillus and Thermoanaerobacter CGTases and the remaining enzymes The positions of the two CGTases from K pneumoniae and Nostoc sp PCC-9229 are, however, in agreement with the values of ... part of the same enzymes (Figs and 4) can be seen in the present study The four- and five-domain members of GH 13 can be Fig The proposed relationship between four- and five-domain GH 13 members...

Ngày tải lên: 08/03/2014, 08:20

... by the recent findings that different members of the HSF family are able to interact, both structurally and functionally, thereby impacting the actions of their partners The interplay among the ... interactions and post-translational modifications HSF1 is the prototype of all HSFs and the mammalian counterpart of the single HSF of yeasts, nematodes and fruit flies [3,27–29] Deletion experiments of the ... knockout of Hsf1 and Hsf4, the abnormal levels of FGF-7 returned to normal, and proliferation and differentiation of the epithelial cells were stabilized These findings indicate that HSF1 and HSF4...

Ngày tải lên: 18/02/2014, 04:20

... cotyledons and mature leaves, whereas, in the flowers, the anthers, connectives and filaments and the base and tip of the stigmata were stained Similar to BPM2, BPM3 and BPM5 promoter:GUS lines, the root ... cotyledons and in the central cylinder of the root, but not in the lower parts of the hypocotyl (a) Rosette leaves were stained in the vascular tissue of the leaf blade, whereas the petiole and older ... with members of the ERF ⁄ AP2 family (A) Y2H assays demonstrate the assembly of BPM1(1–189) and BPM3 with RAP2.4 and RAP2.13, respectively (B) Schematic drawing of the BPM1 fragment used for the...

Ngày tải lên: 18/02/2014, 06:20

... H Shimano Physiology and pathophysiology of the SREBP family SREBP-1c and lipogenesis The SREBP family consists of three isoforms: SREBP1a, SREBP-1c, and SREBP-2 Each isoform has a different ... Physiology and pathophysiology of the SREBP family H Shimano at G1 [19] In particular, p21 is a direct target of SREBP [20] The role of SREBP-1a in the regulation of cell growth and the cell cycle ... conditions of overnutrition, SREBP-1c expression is elevated, and consequently, the levels of nuclear SREBP-1c protein and lipogenesis are enhanced in the liver and adipose tissues Intake of energy...

Ngày tải lên: 18/02/2014, 13:20

... employed and the presentation of the material in this publication not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any ... However, the published material is being distributed without warranty of any kind, either expressed or implied The responsibility for the interpretation and use of the material lies with the reader ... management of childhood illness: caring for newborns and children in the community v Contents: Manual for the community health worker Facilitator notes Photo book: identify signs of illness...

Ngày tải lên: 21/02/2014, 14:20

... lg of protein) of YYY49 and YYT42 contained approximately and ng of hHSF2, and those of YYT50 and YYT17 contained approximately 0.01 and 0.1 ng of hHSF4, as judged by the intensity of each band ... hHSF4–VP16, without changing the magnitude of the heat shock response (cp3) The mutational analysis of the CRYGA and CRYGC HSEs suggests that the nucleotide sequences and configuration of nGAAn-like units ... promoters These results show that the configuration of nGAAn units in the promoter is important in determining which hHSF members are involved in the regulation of the gene Footprint analysis of the...

Ngày tải lên: 07/03/2014, 00:20

... Resolution of the structure of NADP+-bound FeR revealed that the nicotinamide moiety of NADP+ faces the re-side of the isoalloxazine ring, and that the 2Â-P-AMP moiety is held in the groove between the ... Pro154, Ile156 and Pro161 of the other monomer Similarly, Gly175Ala181 forms an anti-parallel intermolecular b sheet with the b12 of the other monomer, and towards the C-terminus, the subsequent ... of the logarithms of the concentration ratios for oxidized and reduced forms of the mediator versus that of recombinant avoredoxin Reduction titration of avoredoxin by NAD(P)H The reduction of...

Ngày tải lên: 07/03/2014, 02:20

... important One of these, the TRP sequence, includes the start of the C-terminal helix as well as the structured loop between the 1440 ATPase domain and the C-terminal helix and in the 3D structure ... alignments of some of the proteins listed in the PFAM database that contain the Vps4 C-terminal oligomerization domain (PF09336) The sequence of the SRH of each protein is also shown The sequence of the ... clade AAA ATPases and have the AAA domain helix and the C-terminal helix, but not the b domain The distinguishing feature of members of the meiotic clade of AAA ATPases is the SRH motif, which...

Ngày tải lên: 07/03/2014, 05:20

... 205 and 215 nm, indicating that Rv1399c is composed of 22% of a-helices, 25% of b-strand and 39% of random coil The catalytic triad is located at the bottom of a small ˚ ˚ pocket, 20 A length and ... by the amides of Ala163, Gly89 and Gly90, the latter’s being found in the HGGG consensus sequence motif characteristic of members of the HSL family [35] Our model shows that the architecture of ... experimentally Indeed, the presence of Arg213 along with the proximity of the charge relay Asp260 within the active site could be responsible for the modification of the catalytic properties of the catalytic...

Ngày tải lên: 07/03/2014, 16:20

... modelling The aim of the present work was to study the diversity of trypsins in the digestive gland of P argus, with focus on: (a) the position of lobster trypsins within the brachyurins family and ... the wall of the binding pocket and allow the access of bulky residues, like Arg and Lys, whereas the basic side chain of these residues is stabilized by Asp189 (chymotrypsin numbering) near the ... in all other clones PaTry4 was the largest and the least anionic of all trypsins found in P argus No cationic form of the enzyme was found in this work The coding regions of PaTry1a and PaTry1b...

Ngày tải lên: 23/03/2014, 03:20

... of degenerate and specific primers and by rescreening the cDNA libraries The partial clones of XHIVEP2 and -3 covered 5.9 and 3.2 kb of the respective 3¢ ends and included 3¢-UTRs and poly(A)-tails ... representation of the full length XHIVEP1 and the Myc-tagged (MT) deletion mutants Black and white boxes indicate the position of the Znf domains and the serine-rich stripe, respectively The relative ... over the proteins, including several serine-rich stretches [9] The 8578 bp cDNA sequence of XHIVEP1 contains 242 bp of the 5¢-UTR, an open reading frame of 7734 bp and 602 bp of the 3¢-UTR The...

Ngày tải lên: 30/03/2014, 13:20

... participated; the participant was required to be the primary caregiver of the child, and had to be willing to participate throughout the course of the study and to complete the questionnaires at Weeks and ... female, usually mothers, with a mean age of 37.1 years (Table 1) The majority of the subjects were white Because only one of the adults taking part in the study was not the parent of the participating ... coordination of the study and helped to draft the manuscript RD participated in the design and coordination of the study XL contributed statistical analysis and helped to draft the manuscript RA and LA...

Ngày tải lên: 18/06/2014, 22:20

... SMP, IAP, JWV and PJA conceptualized the rationale and design of the study, ACS and CMV performed the statistical analysis and interpretation of the data, ACS, SMP and PJA drafted the manuscript ... cross-cultural adaptation, the group of specialists stated that the concept of the impact of childhood cancer on the quality of life of the families used for development of the original instrument was ... Health and Quality of Life Outcomes 2008, 6:35 the health-related quality of life of parents/guardians The score is computed as the sum of the 20 item scores on the Physical, Emotional, Social and...

Ngày tải lên: 18/06/2014, 22:20

... direct role in the disruption of the immune response of the infected lepidopteran larva, but rather that they contribute to the manipulation of lepidopteran host larval growth and development ... Variations in the number of transcripts during the first day after parasitism have also been suggested for members of this gene family by Northern-blot analysis [14] Altogether, these results ... co-localizes with the rep5 segment and secondly with another segment of lower size (Figure 1, rep6 lane) The faint hybridization band obtained with the rep7 probe had a size similar to that of the lower...

Ngày tải lên: 20/06/2014, 01:20

... participated; the participant was required to be the primary caregiver of the child, and had to be willing to participate throughout the course of the study and to complete the questionnaires at Weeks and ... female, usually mothers, with a mean age of 37.1 years (Table 1) The majority of the subjects were white Because only one of the adults taking part in the study was not the parent of the participating ... coordination of the study and helped to draft the manuscript RD participated in the design and coordination of the study XL contributed statistical analysis and helped to draft the manuscript RA and LA...

Ngày tải lên: 20/06/2014, 16:20

... important to the lives of the riverines and the presence of these tools in every visited house may be an indicator of the relative abundance of the species in the reserve Feathers of the bare-faced ... of the caoutchouc epoch, in the second half of the XXth century, many residents of the reserve had migrated to the cities, leading to a decrease of the local population, and a diminution of the ... effectively estimate the population size of these species, hence their conservation status, and to deepen our understanding of the role of Cracidae in the forest equilibrium of this region of the Oriental...

Ngày tải lên: 10/08/2014, 09:21

... and five orders, finds acceptance as food by the locals Out of the 81 species, are representatives of the Odonata, 17 of the Orthoptera, 16 of the Hemiptera, 15 of the Hymenoptera and 24 of the ... rainfall of 3000 mm and temperatures ranging from 5°C in the month of December to 38°C in the month of July The total population of the district, which is inhabited by not only members of the Galo, ... stages of insects taken are quite similar between the two tribes However, the total number of species consumed by the Nyishi Bangni of the East Kameng district is higher than that of the Galo of the...

Ngày tải lên: 10/08/2014, 09:21

... medicinal by members of the Irular, Mudugar and Kurumbar tribes of the Western Ghats of Kerala [60] Except for the Ao Naga of Nagaland [49] and the Nyishi and Galo of Arunachal Pradesh the use of the ... Naga of Nagaland use the same material to improve the overall vitality of a person and the fat of this reptile to treat rheumatism and pains of the joints [49,59,60] The flesh of the crow is used ... use the fat of the crow in cases of smallpox and malaria [27] Members of the Nyishi and Galo tribes use the gall bladder of the mithun (Bos frontalis) in potions to stop dysentery, cough, and...

Ngày tải lên: 10/08/2014, 09:21

... performed the literature search and assisted in the writing of the manuscript MJW oversaw the study and assisted with the writing of the manuscript All authors read and approved the final version of the ... interpretation of patient samples Authors’ contributions TWC was involved in the design of the study, assisted in the literature search and wrote and revised the manuscript DF was involved in the design of ... laboratory, radiological and clinical details of these cases and our own are shown in Table Of the 21 cases retrieved in our literature search, 57% of the patients were men, and overall the patients’ median...

Ngày tải lên: 10/08/2014, 23:21