fail safe and fail dangerous for models

... children These safeguards include federal regulations and international standards for research conduct and systems for research review and monitoring The safeguards also provide for the application ... Press Safe and Effective Medicines for Children: Pediatric Studies Conducted Under the Best Pharmaceuticals for Children and the Pediatric Research Equity Acts Safe and Effective Medicines for ... Conclusions SAFETY AND EFFICACY ASSESSMENTS IN STUDIES CONDUCTED UNDER BPCA AND PREA Sources of Information About Safety and Efficacy Results in Pediatric Drug Studies Assessing and Monitoring Safety...

Ngày tải lên: 23/03/2014, 00:20

Ngày tải lên: 12/05/2014, 15:38

... correction achieve the maximum accuracy and safety for the patient The systematic/random errors at initial set-up were 1.4/ 3.0, 2.1/4.1 and 2.3/3.2 mm in the LR, SI and AP axes, respectively After set-up ... were 14.8%, 10.7% and 14.5% in the mean dose, V20 and V12.5 of the lungs; 19.9%, 33.3%, 29.6% and 21.1% in the mean dose, V30, V20 and V10 of the liver; 21.9%, 42.9%, 23.8% and 20.5% in the mean ... calculated For each patient individually the mean (systematic error) and standard deviation (random error) of all errors were calculated The systematic uncertainty Σ is defined as the standard deviation...

Ngày tải lên: 09/08/2014, 09:22

... row and column m + to create M (delete column m + in H) k and note that represented where and I has order m — Clearly, i is of full-column rank and is a candidate for X k k When x and ... dominance and epistasis Models which include only additive effects and covariates for inbreeding (eg, Hudson and Van Vleck, 1984) are rough approximations The proper treatment of inbreeding and dominance ... gametes, i > j, k, m, k > m, and parent gametes ofi are x and y The proofs of these formulae are due to properties involving sums of expectations and conditional expectations For example: are where...

Ngày tải lên: 14/08/2014, 20:20

... target language words For SCFG models and sequential tagging models, a node also corresponds to a source span and non-terminal type, but for word-based and phrase-based models, the relationship ... generic addition and multiplication operation, ⊕ and ⊗, and their identities and Multiplication and addition must be associative Multiplication must distribute over addition, and v ⊗ The design ... 30 candidates at each node and no further pruning All decoders produced a BLEU score between 31.4 and 31.6 (small differences are accounted for by different tie-breaking behavior and OOV handling)...

Ngày tải lên: 07/03/2014, 22:20

... shipping document for both dangerous and non -dangerous goods, the following rules apply: • List the information for the dangerous goods before the non -dangerous goods and under the heading Dangerous ... Marking Dangerous Goods Containers of dangerous goods must have safety marks and labels applied before they can be shipping In general, dangerous goods safety marks must be visible, legible and displayed ... the movements of the dangerous goods and therefore, bears the least responsibility for the safety of the shipment The receiver is responsible for the following: • Ensuring the dangerous goods are...

Ngày tải lên: 23/03/2014, 08:21

... Zealand, the United States and Canada) and 48% of those in developing countries (i.e., Africa, Latin America and the Caribbean, Asia excluding Japan, and Oceania excluding Australia and New Zealand) ... the one hand, and social disapproval and discrimination against PLHIV having children, on the other hand [4,6,7,38] As Gogna et al point out: [T]raditional gender roles and expectations and the ... children and family structures; and choosing to reserve resources to care for children they already have or for themselves and their partners [6,7,14,39,51] Building reproductive choice for WLHIV...

Ngày tải lên: 20/06/2014, 08:20

Ngày tải lên: 13/08/2014, 20:21

... instructions The actual EIA test has sensitivity and specificity for HBsAg of 100% and 99.94%; for anti-HBc of 99.53% and 99.5%; and for anti-HCV of 100% and 99.8%, respectively as claimed by producers ... an urgent issue in order to set standards for safe blood transfusion where HBV infections are endemic ELISA test is considered as standard test for testing HBV and HCV in developing countries However, ... type 1a and 1b [127] Genotypes 1, 2, and of the Hepatitis C virus (HCV) are widely distributed throughout Western countries and the Far East (Japan, China, Taiwan, and Thailand) Types and are...

Ngày tải lên: 03/03/2015, 21:05

... for multiple projects, including probabilistic earthquake and climate risk models for the Americas and Europe She earned a BS in civil and environmental engineering from Stanford University and ... information Strong, Safe, and Resilient  •  http://dx.doi.org/10.1596/978-0-8213-9805-0   xi   xii Foreword through an open-source platform for projects on urban development, risk financing, and ... Strong, Safe, and Resilient DIREC TIONS IN DE VELOPMENT Environment and Sustainable Development Strong, Safe, and Resilient A Strategic Policy Guide for Disaster Risk Management in East Asia and...

Ngày tải lên: 08/08/2015, 19:23

... mean and variance of demand are known Roels and Perakis [96] generalized this model to incorporate additional moments and information on the shape of the demand On the other hand, if the demand ... when µ = randn(N, 1), σ = 62 rand(N, 1) 4.2 85 Gap and CPU time for different parameters u when µ = randn(N, 1), σ = 85 4.3 Gap and CPU ... develop compact MILP formulations for the minmax regret problem (2.4) (refer to Yaman et al [121] and Kasperski [76]) The minmax regret models handle support information and assumes that the decision-maker...

Ngày tải lên: 10/09/2015, 09:29

... (i.e., n = and n = 10) are studied For each scenario, 30 instances are randomly generated and solved by CPLEX and proposed GRASPs, respectively Both GRASP_1 and GRASP_2 are coded in Matlab and executed ... existing models for the problems of quayside CHAPTER INTRODUCTION operations and provide the revised model and new algorithms for solution (see the work in Chapter 4); • Extend the existing models ... that apart from the aforementioned analytical models for BAP, simulation techniques have also been applied to handle the problem, such as the works by Legato and Mazza (2001) and Henesey et al (2004)...

Ngày tải lên: 10/09/2015, 15:48

... Yingzhu and Wang Runzhi, for their care and support in Singapore I am deeply indebted to my parents for their unconditional love and to my wife Dr Han Zheng for her understanding, support, and loving ... A+B v1 v2 AB (2.1) where A and B are substrates, AB denotes the formed complex, and v1 and v2 represents CHAPTER BACKGROUND AND RELATED WORK 20 the association rate and dissociation rate respectively ... them for being kind, friendly, and fun My time at NUS has been wonderful because of all of them Finally, I want to thank my family I thank my cousins, Liu Mei and Cai Xiaoming, and my uncle and...

Ngày tải lên: 10/09/2015, 15:48

... ), and Biases 𝜎 2𝜈 and Mean Square Errors (MSE) of estimator ˆ1,𝑛 𝛼1 for 𝑑 = 2, 𝜎 = 𝜎 2𝜈 1, 𝛼 = 5, 𝛼1 = 7.5 and 𝜙2,1 (x/𝛾 𝑛 ) 80 Table 3.1 means of the estimators and standard ... Percentiles (standard errors in parentheses), Means and Stan√ √ dard Deviations (SD) of 𝑛(ˆ1 𝛼1,𝑛 − 𝜎 𝛼2𝜈 )/( 2𝜎 𝛼2𝜈 ), and Biases 𝜎 2𝜈 and Mean Square Errors (MSE) of estimator ˆ1,𝑛 𝛼1 for 𝜎 = 1, ... Percentiles (standard errors in parentheses), Means and Stan√ √ dard Deviations (SD) of 𝑛(ˆ1 𝛼1,𝑛 − 𝜎 𝛼2𝜈 )/( 2𝜎 𝛼2𝜈 ), and Biases 𝜎 2𝜈 and Mean Square Errors (MSE) of estimator ˆ1,𝑛 𝛼1 for 𝜎 = 1,...

Ngày tải lên: 11/09/2015, 10:01

... of random forests for modeling and mapping forest canopy fuels for fire behavior analysis in Lassen Volcanic National Park, California, USA For Ecol Manage 279:77À89 Pourghasemi HR, Goli Jirandeh ... important factor for forest fire occurrence is land use type The relationships between forest fire locations and land use types show that 99.06% of forest fire falls on dense forest area with ... methods and techniques for forest fire susceptibility and risk mapping have been proposed and tested Many studies have evaluated forest fire using geographic information system (GIS) and remote...

Ngày tải lên: 25/04/2016, 07:43

Ngày tải lên: 04/10/2012, 10:02

Ngày tải lên: 04/10/2012, 10:02

... Dictionary for Regulatory Activities (MedDRA) Version 7.0 Reported AEs were monitored and recorded throughout the study and for 30 Page of 12 (page number not for citation purposes) Child and Adolescent ... Ritalin LA (8.7), and improvement for girls (16.3) was nearly double the improvement noted for boys Page of 12 (page number not for citation purposes) Child and Adolescent Psychiatry and Mental Health ... (Concerta, Ritalin LA, and Metadate CD), age (6-9 year olds and 1012 year olds), and gender Scores for the AIM-C Child Impact Scale, Family Impact Scale, Medication Tension/Worry Scale, and MissedDoses...

Ngày tải lên: 25/10/2012, 10:06

... January and February, it was safety Travelling the roads was difficult and unpredictable and very unsafe And so families felt trapped Because it was life-threatening for them to go on the roads and ... use standard encounter forms at all AMPATH clinic visits recording http://amrs.iukenya.org/download/forms, information from patient interviews and exams on paper forms Data from the paper forms ... referral clinic and at 17 rural and outlying outpatient clinics.[20,23] A computerized medical record system supports clinical care and research,[24] and the outcomes and adherence of adult and pediatric...

Ngày tải lên: 25/10/2012, 10:31

... miscarriages, and livedo reticularis Materials and Methods We focused on the secondary prevention of stroke with APS, and compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation ... committee of Tokai University, and prior informed consent was obtained from all patients who were eligible to participate Randomization was performed using a randomly generated score Results ... Int J Med Sci 2010, with APS We therefore compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke...

Ngày tải lên: 26/10/2012, 09:48