facs of epc in rat blood samples
Báo cáo y học: "Invasive and noninvasive methods for studying pulmonary function in mice" ppsx
... parameters can be determined including breathing frequency, inspiratory and expiratory time as well as the maximum box pressure during inspiration and expiration None of these variables is specific ... benefits of noninvasive technology has renewed interest in analyzing expiratory tidal flow patterns as a tool in the assessment of airway obstruction Although noninvasive measurement of murine respiratory ... horizontal line at zeroflow separates inspiratory (Insp; upward; +) from expiratory (Exp; downward; -) airflow V, tidal flow VT, tidal volume TI, time of inspiration TE, time of expiration Figure...
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Báo cáo y học: "Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia" ppsx
... ELF amikacin concentration and ventilator settings (respiratory rate, peak inspiratory flow rate, mode of ventilation), presence of acute respiratory distress syndrome at the time of inclusion ... expiratory filter (Figure 1b) In this configuration, the aerosol was generated continuously (not only during inspiration), and nebulization of the dose was completed in approximately 15 to 20 minutes ... Reliability of mini-bronchoalveolar lavage for the measurement of epithelial lining fluid concentrations of tobramycin in critically ill patients Intensive Care Med 2007, 33:1519-1523 Goldstein I,...
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Báo cáo khoa học: " Erythropoietin response in critically ill mechanically ventilated patients: a prospective observational study" pot
... assisted in executing the study, analyzing the data, and drafting the manuscript MWQ and DEL participated in the original design and coordination of the study, and in writing the original protocol ... increase [7-9] Anemia of critical illness and blood management strategies in the ICU continue to be areas of active research Two recent trials [10,11] demonstrated a reduction in the number of ... hemoglobin 7.0 g/dl, goal 7–9 g/dl) transfusion strategy in 713 mechanically ventilated patients, representing a subgroup of a larger study [12] That study found no difference in the duration of mechanical...
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Optimal security design and dynamic capital structure in a countinous time agency model DEMARZO & SANNIKOV
... time t, he gains immediate income of ˆ ˆ λ ( dYt − dYt ) but loses β t ( dYt − dYt ) in continuation payoff Therefore, the payoff from reporting strategy Ŷ gives the agent the payoff of τ ⎡ τ −γ ... were continuous, as long as the marginal cost to the agent of increasing the drift remained constant at λ 26 Formally, (23) is needed in the proof of Proposition for Gt to remain a supermartingale ... to pay off the credit line before paying dividends, and, once the credit line has been paid off, to pay dividends rather than hoard cash to generate additional financial slack In the continuous-time...
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Reproductive senescence and dynamic oviposition behaviour in insects potx
... (Figs 2, 3) The fraction of insects becoming egg-limited is an increasing function of host availability k Insects that develop on hosts that support greater egg numbers (single host maximum clutches) ... 1988) to determine oviposition behaviour, keeping the deterministic setting The dynamic model explicitly incorporates the host encounter rate and thus allows clutch size to vary according to both ... ospring performance, and intergenerational ®tness Behav Ecol 5, 412±417 Minkenberg, O.P.J.M., Tatar, M and Rosenheim, J.A (1992) Egg load as a major source of variability in insect foraging and...
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Báo cáo hóa học: " Research Article Distributed and Collaborative Node Mobility Management for Dynamic Coverage Improvement in Hybrid Sensor Networks" doc
... “Analytical modeling of detection latency in mobile sensor networks,” in Proceedings of the Conference on Information Processing in Wireless Sensor Ntworks (IPSN ’06), April 2006 [8] T.-L Chin, P Ramanathan, ... nodes increases, it can be seen from Figure 12 that the rate of increase of the mean of the presence probabilities of the void cells also increases These observations validate the effectiveness of ... Computing and Networking, pp 139–150, July 2001 [20] G Barriac, R Mudumbai, and U Madhow, “Distributed beamforming for information transfer in sensor networks,” in Proceedings of the 3rd International...
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Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx
... determined preoperatively and again on day using an incapacitance meter (IITC, Inc.) Briefly, an incapacitance meter consists of two scales and specialized caging to encourage a rearing posture in ... Pathogenesis of sciatic pain: a study of spontaneous behavior in rats exposed to experimental disc herniation Spine (Phila Pa 1976) 2002, 27:1312-1317 Winkelstein BA, Weinstein JN, DeLeo JA: The role of ... Anti-TNF-alpha antibody reduces pain-behavioral changes induced by epidural application of nucleus pulposus in a rat model depending on the timing of administration Spine (Phila Pa 1976) 2007, 32:413-416...
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Dynamic performance improvement in boost and buck boost derived power electronic converters
... converter’s operating point This is due to linearization at the operating point during the modeling process As a result, the model parameters vary significantly when the operating point shifts In general, ... frequency-domain effects of RHP zero in the boost converter operating in CCM are explained in detail For the purpose of explanation, let us consider an ideal boost converter (Fig 1.1) having the following ... An increase in control input (duty ratio of S in Fig 1.1) initiated by a dip in the output voltage causes an increased output-capacitor-discharge-time This results in the output voltage dipping...
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Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice ppt
... expression of CB1 in isolated cortical neurons was affected in both strains of R6 transgenic HD mice It appeared that the amino terminus of mutant huntingtin containing an expanded polyglutamine tract ... abnormalities in cannabinoid signalling or modulation of dopamine signalling or both have been implicated in a number of neurodegenerative diseases including HD and Parkinson disease, and in other ... transgenic lines of HD mice include the length of the CAG repeat within the HD transgene and the site of integration of the transgene [10], which appears to lead to differences in the amount of protein...
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báo cáo hóa học: " The effect of consequent exposure of stress and dermal application of low doses of chlorpyrifos on the expression of glial fibrillary acidic protein in the hippocampus of adult mice" pptx
... http://www.occup-med.com/content/6/1/4 Page of Figure Photomicrograph showing the immunohistochemical staining of GFAP expression in stratum moleculare-lacunosum of the hippocampus in groups of mice at the end of experiment ... to be increased following toxic insult to the CNS in many studies A single subcutaneous injection (50 μg/kg bw, 1/2 LD50) of the cholinesterase inhibitor Sarin was found to significantly increase ... Kishk AM, Abou Donia MB: Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats J Toxicol Environ Health...
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báo cáo hóa học:" Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice" pot
... in the ovary was investigated following in vivo and in vitro administration of GnRH agonist in the intact cyclic mice Methods Animals All the experiments were conducted in accordance with principles ... (stained with haematoxylin-eosin) of cyclic mice showing histological changes following administration of different doses of GnRH-Ag: (A) The ovary of control mice showing normal corpus luteum ... mice Increase in the expression of caspase-3 and cleaved PARP proteins noticed in the mice treated in vivo with GnRH-Ag also showed increase in the number of atretic follicles in the ovary In an...
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Báo cáo hóa học: " Sleep quality in mechanically ventilated patients: comparison between NAVA and PSV modes" doc
... were clinically adjusted by the attending physician to obtain a tidal volume of mL/kg of predicted body weight and a respiratory rate ≤ 35 breaths/min For both modes of ventilation, inspiratory ... concerning the rate of fragmentation, the number of central apneas, and the number of ineffective patient efforts during PSV Another similar finding concerned the increased percentage of REM ... too low in COPD patients resulted in an increase in imposed work of breathing, which can be accounted for in the decrease in SWS and REM The Toublanc study offers no information on expiratory...
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Báo cáo y học: "The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice" docx
... protein (G protein), gamma 10 230657 Tmem69 Transmembrane protein 69 1.7 16008 Igfbp2 Insulin-like growth factor binding protein 1.7 73723 Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like ... protein 54 (Tmem54), coiled coil domain containing 28B (Ccdc28b) and testis-specific serine kinase (Tssk3) all to be downregulated Furthermore, we found zink finger and BTB domain containing (Zbtb8) ... or in some cases one minor focal infiltrate, whereas the number and the severity of infiltrates in the NOD congenic mice increased considerably In order to assess the effect that addition of...
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Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene ppt
... essential role in the formation of opioid tolerance [13] Co-administration of morphine with delta Page of Figure Antinociceptive effect of naloxone in MOR-KO mice determined using tail-flick tests before ... effects of naloxone (s.c.) or morphine at a dose of 10 mg/kg (s.c.) were determined separately in all 12 mice In order not to confuse the reader, we have deleted the data of morphine at a dose of ... protein (EGFP) gene into the sacral spinal cord of healthy wild type Imprinting Control Region (ICR) mice We found that a single injection provided sustained gene expression in the spinal cord for...
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Báo cáo y học: "Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport" doc
... PiT1-binding immunoadhesin generated by fusing the aminoterminal residues of the GALV (SEATO strain) Env, comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, ... were not stained with any of the three markers In the Substantia Nigra: no distinct binding of the GLUT1 ligand was detected, with the structure rather presenting a diffuse staining (data not ... SNpr CP GL Figure PiT2 immunostaining in normal mice A: PiT2 immunostaining in the cortex of a normal mouse In this representative image, the staining is detected in all cortical layers, with a...
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Báo cáo y học: "Response of the mouse lung transcriptome to welding fume: effects of stainless and mild steel fumes on lung gene expression in A/J and C57BL/6J mice" pot
... S100 calcium binding protein A9 [S100A9], etc.) other "later" gene interactions were surprising (Figures and 5) Perhaps the most intriguing finding regarding GMA-MS welding fume Page of 18 exposure ... corresponding sham alteration of genes under the higher level function of behavior and nervous system development and function These genes including D site of albumin promoter (albumin D-box) binding ... thereby delaying the recovery from welding fume-induced lung inflammation Additionally, our results provide unique insight into strain- and welding fume-dependent genetic factors involved in the lung...
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Báo cáo y học: "An intranasal selective antisense oligonucleotide impairs lung cyclooxygenase-2 production and improves inflammation, but worsens airway function, in house dust mite sensitive mice" ppsx
... 100 Methacholine (mg/ml) Figure reactivity to increasing concentrations of aerosolized methacholine Airway Airway reactivity to increasing concentrations of aerosolized methacholine Airway reactivity ... hyperreactivity Increasing doses of methacholine induced a dose-dependent rise in Penh in all experimental groups (Figure 4) The Penh increase was higher in the HDM-sensitized mice than in the non-sensitized ... protein expression and the assessment of its activity by measuring the production of one of its main products, PGE2 [41] Irrespective of the variable considered, the degree of inhibition of airway...
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Báo cáo y học: " Different effects of deep inspirations on central and peripheral airways in healthy and allergen-challenged mice" ppt
... Our results in the chronic airway inflammation are in line with those of Schweitzer et al [24], who showed that DI in Brown Norway rats, protected against MCh-induced increases in respiratory system ... given twice during the minute before assessment of lung mechanics, DI is defined as incremental increase and decrease of three times VT during a period of 16 s Mice not receiving DI, were given ... effectin healthy lung compliance (CL) presented as ∆CL Figureof deep inspirations (DI) of DI on mice; (A) lung resistance (RL) in mice given incremental doses of methacholine Effects Effects of...
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Báo cáo y học: " Equipment review: Pulmonary uptake and modes of administration of inhaled nitric oxide in mechanically-ventilated patients" ppt
... inspiratory NO concentration As shown in Fig 7, any change in the patient’s inspiratory drive resulting in variations in tidal volume, inspiratory flow and duration induced fluctuation in inspiratory ... concentration Continuous administration Principle This method of administration consists of delivering a continuous flow of NO (regulated by a nitrogen flow meter) into the proximal end of the inspiratory ... Y-piece; ci = continuous administration into the inspiratory limb; cy = continuous administration into the Y piece Published with permission [3] During inspiration, the bolus passes sampling sites at...
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Báo cáo y học: "Enteral feeding in the critically ill: comparison between the supine and prone positions A prospective crossover study in mechanically ventilated patients" pdf
... emptying and the ability of continued enteral feeding We studied tolerance of enteral feeding in mechanically ventilated patients in the prone position by measuring the gastric residual volume in ... caloric intake Interruption of enteral feeding may lead to insufficient nutrition It is therefore important to know whether enteral feeding can be continued in a position other than the supine position ... supine position Univariate ANOVA could not detect the use of pro-kinetics, sedation or the type of enteral nutrition as significant factors in explaining the amount of gastric residual volume in...
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