facilitating good glycemic control and quality of life deborah young hyman
Tài liệu Growth and nutritional status of children with homozygous sickle cell disease ppt
... (weight and height ,5th centile) led to a rapid and sustained increase in growth and a reduction of pain crises and episodes of infection.15 The authors found no lipid malabsorption and a normal ... race-matched controls (11–40 yrs) There was delay in onset of menarche and age at first pregnancy, decreased fertility and an increased incidence of abortion and premature delivery In a separate group of ... study of 86 SS patients under 20 years of age reported weight and height ,10th centile in 40% and 31% of cases, respectively, and the weight deficit persisted after puberty.43 In a follow-up of...
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báo cáo hóa học: " Quality of life among adolescents with sickle cell disease: mediation of pain by internalizing symptoms and parenting stress" pdf
... PD, PJ R, Cohen-Kettenis PT, Imhof SM: Health-related quality of life of child and adolescent retinoblastoma survivors in the Netherlands Health and Quality of Life Outcomes 2007, 5:65 Vance YH, ... to the conception and design of the study, acquisition of data, analysis and interpretation of data, and drafting and revision of the manuscript She has given final approval of this version for ... Hydroxyurea and sickle cell anemia: effect on quality of life Health & Quality of Life Outcomes 2006, 4:59 Maikler VE, Broome ME, Bailey P, Lea G: Children's and adolescents' use of diaries for...
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Báo cáo y học: " The use of partial exchange blood transfusion and anaesthesia in the management of sickle cell disease in a perioperative setting: two case reports" pot
... haemoglobin and a haematocrit of 0.09 HPLC revealed an HbS fraction of 32.3%, HbA2 of 2.3%, and HbF of 1.1% He had to undergo several surgeries, including sequestrectomies, drilling of the medullary ... of unit of red blood cell 4.4 0.21 General anaesthesia to insertion of central venous line 3.9 0.18 Transfusion of unit of red blood cell 5.2 0.24 Sequestrectomy tibia, transfusion of units of ... transfusion of units of red blood cells In addition to classical triggers, the activation of endothelial factors, immunological responses and other factors modulate the onset and course of the disease and...
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Báo cáo y học: " Depression and loneliness in Jamaicans with sickle cell disease" potx
... of societal and health care providers’ response to these persons [9,21] No studies have looked at the co-existence of depression and loneliness in SCD and it is hypothesized that depression and ... such as fatigue and loss of energy, a higher cut-off of 17 was utilized Logistic regression was used to examine the relationship between independent variables and depression, and multivariate ... years), with equal proportions of males and females in each subgroup (Table 1) A significantly greater proportion of the controls had higher levels of educational attainment and was employed The mean...
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Báo cáo y học: "Asthma is a risk factor for acute chest syndrome and cerebral vascular accidents in children with sickle cell disease" ppt
... far reaching and could make enormous impacts on the morbidity, quality of life and mortality of many patients Competing interests A randomized, placebo-controlled trial of 43 episodes of acute chest ... The cases and controls were well-matched for age, gender and type of hemoglobinopathy (Table I) The cases (21 males and 27 females) consisted of 42 children with HgbSS and with HgbSC The control ... chart review of 48 children with asthma and sickle cell disease and compared them to a control group of 48 children with sickle cell disease alone The 48 children with sickle cell and asthma represented...
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Tài liệu Parental Attitude to Children with Sickle Cell Disease in Selected Health Facilities in Irepodun Local Government, Kwara State, Nigeria doc
... any time and psychosocial trauma of the knowledge of imminent death More importantly, the victims may be unable to realize/ actualize his dreams in life and there is denial of some rights and privileges ... Sometimes there is an overwhelming sense of frustration, the blame of self and also of partners and feelings of inadequacies are not uncommon but for the majority of parents, these are transient emotions ... of clinics for their children by the researchers and hospital heads so that they could be explained to the objectives of the study, given assurance of confidentiality of information offered and...
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Tài liệu Understanding Growth Failure in Children With Homozygous Sickle-Cell Disease doc
... measures of weight, height, and BMI The purpose of this article is to explore the patterns of growth in children and adolescents with SCD, as well as to gain insight into the multifactorial causes of ... intake of vitamins D and E, folate, calcium, and fiber was suboptimal for the total sample of children with SCD-SS As high as 85% of children fell below the estimated average requirement Intake of ... baseline dietary intake of zinc was not significantly different between the zinc and control groups (Zemel et al., 2002) The results of these studies examining vitamin D, vitamin A, and zinc status suggest...
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Tài liệu THE MANAGEMENT OF SICKLE CELL DISEASE ppt
... penicillin by months of age, and parents should be educated about the importance of urgent medical evaluation and treatment for febrile illness and for signs and symptoms indicative of splenic sequestration ... availability, quality, and integration of all five components of the neonatal screening system: screening, follow-up, diagnostic testing, disease management and treatment, and evaluation of the entire ... conditions and have a normal life expectancy The inheritance of SCT should have no impact on career choices or lifestyle SCT is found in percent of African Americans and is also prevalent in persons of...
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Hydroxyurea for the Treatment of Sickle Cell Disease docx
... The methodological quality of the MSH was excellent (Jadad score of 5, out of a maximum of 5) and that of the Belgium study was moderate (Jadad score of 3), because the method of masking was not ... Research and Quality Jean Slutsky, P.A., M.S.P.H Director, Center for Outcomes and Evidence Agency for Healthcare Research and Quality Barry Kramer, M.D Director, Office of Medical Applications of ... Institutes of Health Office of Medical Applications of Research (OMAR) and the Agency for Healthcare Research and Quality (AHRQ) requested that the Evidence-based Practice Center (EPC) of the Bloomberg...
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Management of Sickle Cell Disease in Children doc
... extremes of heat and cold Often, no cause is identified CPG 21-1 Management of Sickle Cell Disease in Children Page of 15 Inclusion Criteria: • Sickle cell patients presenting with signs of VOC ... Streptococcus pneumoniae and Haemophilus influenzae type B If special measures are not taken, 15-20% of infants and young children with sickle cell anemia die before the age of 5, usually of septicemia ... q4h, and before and after each pain medication and non-pharmacologic intervention (heating pads, warm baths, other comfort measures such as imagery and distraction) Encourage ambulation and activity...
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Psychological complications in sickle cell disease pptx
... management of patients with SCD and offered as standard care to help improve their general quality of life References Adams, P.C & Speechley, M (1996) The effect of arthritis on the quality of life ... other factors such as mood and activities (Anie & Steptoe, 2003), and inappropriate painrelated behaviour or coping strategies (Elander et al, 2004) Quality of life Activity and functioning Impaired ... 2002b) (Fig 1) In spite of this, SCD pain, clinical status and health service utilization seem to make only a limited contribution to understanding the pattern of poor quality of life, suggesting that...
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báo cáo hóa học: " A psychometric evaluation of the PedsQL™ Family Impact Module in parents of children with sickle cell disease" pptx
... 20 21 22 23 24 25 Sales E: Family burden and quality of life Qual Life Res 2003, 12(Suppl 1):33-41 Helgeson VS: Social support and quality of life Qual Life Res 2003, 12(Suppl 1):25-31 Moskowitz ... determinant of caregiver report of pediatric asthma quality of life Ann Allergy Asthma Immunol 2002, 89:572-577 Spilker B: Quality of Life and Pharmacoeconomics in Clinical Trials Lippincott Williams and ... reliability, and validity Qual Life Res 2006, 15:203-215 Raat H, Landgraf JM, Oostenbrink R, Moll HA, Essink-Bot ML: Reliability and validity of the Infant and Toddler Quality of Life Questionnaire...
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báo cáo hóa học: " Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease" docx
... citation purposes) Health and Quality of Life Outcomes 2009, 7:75 ence of painful crises in SCD is a very prevalent and severe complication of the disease [38,39], and those with higher pain ... Health and Quality of Life Outcomes 2009, 7:75 ical complications in patients with SCD mainly result from the impact of pain and symptoms on their daily lives and society's attitudes ... Quality of Life Assessment: development and general psychometric properties Soc Sci Med 1998, 46(12):1569-1585 WHOQOL Group: Development of the World Health Organization WHOQOL-BREF quality of...
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báo cáo hóa học:" Spectrum of musculo-skeletal disorders in sickle cell disease in Lagos, Nigeria" doc
... sites 60 (60.0%) of these were males and 40 (40.0%) were females, giving a male: female ratio of 1.5:1 The ages of all the patients ranged between and 45 years, with a mean of 14.2 ± 11.5 years ... to represent 6-11% of bone and joint manifestations of SCA [11,31,32] The relatively higher value of 15.3% found in this study may not be unrelated to the preponderance of young patients, who ... doubt that there is upward surge in life expectancy of SCA patients due to better understanding and correct management of the complications [6] Also provision of modern diagnostic facilities such...
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báo cáo hóa học:" Double disadvantage: a case control study on health-related quality of life in children with sickle cell disease" potx
... health-related quality of life? Results of a systematic review Qual Life Res 2001, 10:347-357 26 Varni JW, Limbers CA, Burwinkle TM: Parent proxy-report of their children’s health-related quality of life: ... drafted and revised the manuscript JO, HH and MP supervised execution of the study and revised the manuscript MAG designed and supervised execution of the study, interpreted the data and drafted and ... Impact of family income and sickle cell disease on the health-related quality of life of children Qual Life Res 2009, 18:5-13 18 McClellan CB, Schatz J, Sanchez C, Roberts CW: Validity of the...
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báo cáo hóa học:" Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease" doc
... citation purposes) Health and Quality of Life Outcomes 2009, 7:75 ence of painful crises in SCD is a very prevalent and severe complication of the disease [38,39], and those with higher pain ... Health and Quality of Life Outcomes 2009, 7:75 ical complications in patients with SCD mainly result from the impact of pain and symptoms on their daily lives and society's attitudes ... Quality of Life Assessment: development and general psychometric properties Soc Sci Med 1998, 46(12):1569-1585 WHOQOL Group: Development of the World Health Organization WHOQOL-BREF quality of...
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Báo cáo y học: "Treatment of stasis dermatitis using aminaphtone: Collapsing glomerulopathy in sickle cell disease: a case report" pps
... 2) is a morphologic variant of FSGS characterized by segmental and global collapse of the glomerular capillaries, marked hypertrophy and hyperplasia of podocytes and severe tubulointerstitial ... (IgG), IgA, IgM, C1q, C3, fibrin, albumin and and l chains A diagnosis of CG was considered and lupus was excluded Extensive searches for the main causes of CG were negative Parvovirus B19 (PVB19) ... form of FSGS is a histologic variant which is characterized by mesangial hypercellularity and resultant collapse of the glomerular capillaries Page of Numerous hypotheses for the pathogenesis of...
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Báo cáo y học: " Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease" pot
... fluidity of the bilayer Additionally, there is increased ion permeability, inactivation of membrane enzymes and receptors, and covalent cross-linking of lipid Once molecules such as O2– and H2O2 ... transfer of electrons between Fe and O2, leading to the production of O2– Auto-oxidation of hemoglobin, which occurs to a small extent physiologically, leads to the production of methemoglobin and ... toxic effects because of their ability to react with proteins, nucleic acids, and lipids [16] reports Within RBCs, one of the mechanisms of O2– formation is via the deoxygenation of hemoglobin During...
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Báo cáo y học: "Case Report: Psychosis in an adolescent with sickle cell disease" pps
... frightened and agitated but well dressed and groomed There was loosening of association in his speech and he had abnormality of thought possession He had paranoid beliefs directed at the house-help and ... and step-mother and experienced visual hallucinations Orientation in place, person and time was good Immediate and long term memory were good but short term memory was impaired and he could not ... this episode of mental illness, made good grades and was planning further studies O.J was described as reserved with few friends, often kept to himself, did not like group activities and occupied...
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schaum's easy outline molecular and cell biology - william stansfield, raul j cano, jaime s. colome
... microtubules of the spindle bundle and function to distribute chromosomes as cells proliferate Propagation and maintenance of any piece of DNA requires the presence of one or more origin of replication ... back and forth from a central core of proteins called a scaffold Dephosphorylation of topoisomerase II and other proteins causes dissociation of the scaffold and results in the decondensation of ... of a substrate, two major electron carriers, NAD+ and FAD, become reduced to NADH and FADH2 One complete turn of the TCA produces three molecules of NADH, two molecules of CO2, one molecule of...
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