fabry s disease and the role of fabrazyme® enzyme replacement therapy
Vietnam’s Competitiveness and the Role of the Private Sector potx
... Porter The Role of Business in Social Issues • Business cannot solve all of society s problems, nor bear the cost of doing so – There are many worthy causes • Business must approach its social agenda ... proactively and strategically • Business must address society and social issues where it can add the most value • Where is a company able to have the greatest impact on social issues versus other institutions? ... Plastic sacks, bags Synthetic rubber Motorcycles and Bicycles Parts of other motorcycles Motorcycles and Bicycles Bicycles and other cycles, non-motorized Specialty Office Machines Electrical and...
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Tài liệu Egypt''''s Water Warriors : Water Pollution in Egypt and the Role of NGOs in Reaching Integrated Management ppt
... facilities The use of fertilizers and pesticides has significantly increased after the construction of High Dam and causes weed flourishing, which increases evapotrans piration, blocks the waterways, ... participatory assessment exercises among stakeholders to identify and harness the wealth of knowledge, skills, resources and institutions of importance for integrated management of water resources that ... pollution2 sources in Egypt today are various and Industrial wastes are considered3 the major source On the other hand, about 90% of the rural populations have no access to sewer systems or wastewater...
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Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
... large, the main conclusions of the paper provide ground for a rather pessimistic assessment of the adjustment performances of Russian enterprises in 1996 Profit appears as a function of the capacity ... internal consistency of the data base as well as a series of relationships between the different variables, including profit This also makes possible the identification of four sub-groups of firms, with ... of Russian industrial enterprises, in relationship with the constraints they are facing and the adjustment strategies they show We focus on their relationship with banks, because of its strategic...
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Báo cáo khoa học: Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase A theoretical study using elementary flux modes Stefan Schuster and Dimitar Kenanov ppt
... which is difficult to assess in vivo, is involved in these pathways Since adenine is a substrate of ADPRT, the elevation of ATP in the absence of adenosine kinase shows that adenine must be released ... kinase Purine nucleoside phosphorylase Phosphoribomutase Phosphoribosylpyrophosphate synthetase D-Ribose-5P-isomerase S- Adenosylhomocysteine hydrolase Transaldolase Transketolase Triosephosphate ... -ketoribose þ homocysteine is here referred to as SAHH2 and is assumed to be irreversible because the disintegration occurs spontaneously The complete list of enzymes is given in Table Of course, the...
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Circuit theory of finance and the role of incentives in financial sector reform
... funds; they screen and select potential fund-users on the basis of creditworthiness, assess the quality, risk, and profitability of investment projects, allocate funds, monitor their use, and seek ... producers; along the circuit, the financial system governs the supply and demand of funds and, at the end of the process, it determines the condition for the closure of the circuit As discussed, the ... unnecessary to further improve the bank’ risk position s and counterparties, on their side, might consider for them unnecessary to further assess the riskiness of the bank Finally, the inadequacy of...
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Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc
... enterprises and Government s offices, VIFFAS has always made great efforts to catch the business needs and troubles and therefore create favorable conditions for activities of enterprises The association ... conditions for business associations, as well implemented strategies on developing and increasing the quality of trade services of the Ministry of Trade and the Ministry of Transport Being the intermediary ... Measures should have consensus on Import-Export regulations to prevent contrasts in contents of legal documents and forms of dealing with exports and imports Soon issue the Customs Act specifying the...
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Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"
... associated with seropositivity of pregnant women in Korea J Parasitol 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians ... among persons infected with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated ... Int J Med Sci 2009, 134 aged This is particularly true with regards to T gondii, where the consequences of infection can be very severe, while the risk of living with one s beloved cat is practically...
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Tài liệu Organization-internal Transfer of Knowledge and the Role of Motivation: A Qualitative Case Study pptx
... plants In the subsequent sections we discuss the possible explanations to transfer success and its relation to existing knowledge transfer theory THEORY Knowledge transfer theory has obvious overlaps ... measured in different ways Sometimes it is based on individual assessments about whether the transfer has been successful, requested through questionnaire surveys (Szulanski, 1996) In other studies, ... INTRODUCTION OF THE SIX CASE PLANTS The six plants studied share many features, like technology, machinery, skills levels (many operators and workers go to the same type of schools and colleges and they...
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Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx
... [1] These studies revealed that RecA protein binds to single strand overhangs generated as a result of processing at the DSB site In this presynaptic complex, RecA protein coats single stranded ... that stable changes are associated with homologous strands in the native state of the reaction and involve no protein removal steps Results Strand exchange activity of several recombinases have ... that the steady state changes were stable (Fig 4B, lines and 3) Under the conditions of the assay, deproteinizing 1502 agents SDS, EDTA and proteinase K had no effect on the emission intensity of...
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Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf
... refolding process in terms of assembly of fragments is discussed Results CD spectra Secondary structure of SNase and its mutants was determined by CD with spectrapolorimetry measurements The approximate ... unfolded to the folded state Feng et al [24] created the SNase fragments SNase(1–110), SNase(1–121) and SNase(1–135) and used them in NMR spectroscopy experiments to study the folding process They concluded ... and SNase(1–36) to show that the folding nucleation sites of SNase may start from the N-terminus [25] However, we used the C-terminal fragments SNase(1–140) and SNase(1–142) to show that SNase(1–140)...
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Assessing and Managing Rapid Credit Growth and the Role of Supervisory and Prudential Policies docx
... where there are weaknesses in banks’ and supervisors’ ability to assess and monitor the risks Strengthening the capability of banks and supervisors to better assess and manage indirect exposure ... borrowers use these instruments to cover their exchange and interest rate risks Box further discusses the various ways to assess the nature of credit growth More generally, assessing risks associated ... industries, sectors, or regions); • Use of periodic stress tests of banks’ balance sheets against interest rate, exchange rate, and asset price changes (by banks themselves as well as supervisory...
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DECISION MAKING AND THE ROLE OF ACCOUNTING pot
... knowledge of accounting measurement systems, concepts and standards is desirable The nature of accounting and its main functions Accounting is a service activity It uses words and symbols to communicate ... summarise, there is the establishment of implicit goals, the collection of information about the proposed business, and consideration of future consequences As the business proceeds, accounting ... individuals and business entities buy and sell shares people meet to swap, buy and sell hand-crafted and second-hand goods If accounting information is to be useful, it must be expressed in terms of: ...
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Báo cáo khoa học: Caenorhabditis elegans metallothionein isoform specificity – metal binding abilities and the role of histidine in CeMT1 and CeMT2 potx
... the heterometallic Zn,Cu–CeMT species; however, ESIMS analysis of the samples at acid pH makes it possible to delimit the Cu species present in the sample For the analysis of the apo-MT forms, ... confers a basic detoxification role to this isoform This hypothesis is also concordant with the effects observed in the fitness of C elegans MT-knockout organisms, where the lack of CeMT1 is more ... conditions ESI-MS data comprise theoretical and experimental molecular masses of the Cu–CeMT peptides In the case of Zn,Cu mixed-metal species, the theoretical molecular masses correspond to the homometallic...
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Báo cáo khoa học: The essential tyrosine-containing loop conformation and the role of the C-terminal multi-helix region in eukaryotic phenylalanine ammonia-lyases docx
... LLTFLSAGLINAVATNV LVLSHAAGI LILSHACGV LVRSHSSGV LVRSHSSGV LVRSHSAGV LIRCLLAGV 203 TITASGDLVP TITASGDLVP TISASGDLSP SVGASGDLIP SLGTSGDLGP SVGASGDLAP SLGASGDLAP TVGASGDLAP TVGASGDLAP SLGASGDLAP SVSASGDLIP ... ammonia-lyases Results and discussion Modeling the active conformation of the essential Tyr110-loop of parsley PAL Because of the uncertainty of the arrangement and the role of the essential Tyr110-loop ... following sections further simulations and experimental facts will be presented which may be interpreted by this hypothesis The hypothesis will also be extended to the analysis of the possible role of...
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Báo cáo khoa học: Local stability identification and the role of key acidic amino acid residues in staphylococcal nuclease unfolding ppt
... of their native conformation This hypothesis is supported by the CD results, showing that some secondary structure still exists in these mutants (Fig 1) Thermal analysis of protein unfolding Thermal ... concentration of 0.5 mgÆmL)1 Spectra were obtained as the average of five successive scans with a bandwidth of 1.0 nm and a scan speed of 20 nmÆmin)1 Steady-state tryptophan fluorescence measurements Measurements ... CD with spectrapolorimetry measurements Figure shows the superimposed far-UV CD curves of wild-type SNase and G substitute mutants All mutants other than E129G had similar spectra to the wild-type...
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Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt
... same eight similarly disposed residues Of these, five are able to interact with the )1 site of the substrate, whereas the other three assist in orienting the two catalytic glutamates [13] This ... crystal structure may be relevant The relative activities of the mutants tested showed the same trend for both the hydrolysis and transglycosylation assays The observation that the transglycosylation ... results in a significant loss of catalytic efficiency On the other hand, this loss of activity may be because E192, the catalytic acidbase, now has greater mobility It is possible that the loss of...
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WORKING PAPER NO. 218 THE ZERO-INTEREST-RATE BOUND AND THE ROLE OF THE EXCHANGE RATE FOR MONETARY POLICY IN JAPAN potx
... success The paper proceeds as follows Section reviews the estimated three-country macro model In section we discuss the consequences of the zero-interest-rate bound, first in case of a severe recession ... contract wage shocks that we will use for stochastic simulations is based on the estimated rules Thus, in the final section of the paper we report a sensitivity study that makes use of the estimated ... depreciating, the currency temporarily appreciates in real terms The economy only returns slowly to steady state once the shocks subside Of course, the likelihood of such a sequence of severe shocks is extremely...
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The impact of fodder trees on milk production and income among smallholder dairy farmers in East Africa and the role of research ppt
... another 90 farmers as potential adopters of shrubs Planters of shrubs were oversampled because the study was intended to assess the impact of fodder shrubs, thus requiring a significant number of ... of these differences, and (d) analysis of the cultivation and use of fodder trees across different wealth classes As such, the data cannot be used to infer the rate of adoption of shrubs 6 The ... additional litre of milk Seed systems Most species require nursery establishment; formalization of Numbers of planters of fodder shrubs private seed dealers and marketing of seed Dissemination of information...
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Báo cáo khoa học: Autophosphorylation of heme-regulated eukaryotic initiation factor 2a kinase and the role of the modification in catalysis doc
... results obtained should aid the clarification of the general role of autophosphorylation in catalysis by eIF2a kinases as well as the molecular mechanism of stress sensing In the present study, ... kinase (S- X-X -S ⁄ T), casein kinase (S ⁄ T-X-X-E) and glycogen synthase kinase (S- X-X-X -S) Phosphorylation of HRI by casein kinase has been described previously [23] These findings suggest that other ... J Igarashi et al sensing stress, these eIF2a kinases phosphorylate a common substrate, eIF2a at Ser51, leading to the termination of protein synthesis [3] HRI regulates the translation of hemoglobin...
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