... addition of the exopeptidase). Preparative activation Activation of (Pyr)-ONC (M23L) was performed as described in the Materials and methods. The presence of pyroglutamyl at the N-terminus of the ... for the activation of ONC has no detrimental effect on the conformational stability of the enzyme. Cytotoxic activity The effect of (Met1) removal on the cytotoxic properties of ONC was examined ... terms of reactivity to the matrix and their ionization properties, will not differ significantly. Thus, the relative intensities of the different peaks constitute a fair estimate of the fraction of...
Ngày tải lên: 19/02/2014, 12:20
... the formation of half-a- complex or one unit ( one tetramer of GAPDH, one dimer of PRK and one molecule of CP12) essential to the formation of the native complex by dimerization of this unit [29]. ... that the association of wild-type GAPDH with CP12 resulted in a modification of the kinetic parameters of GAPDH probably through conformation changes of the enzyme upon binding of CP12 [28]. The ... overall structure of these mutants is not different from that of the wild type. The rsmd values obtained for the superimposition of the C a atoms of the wild-type GAPDH wit h those of K128A and K128E...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... Center of Molecular Biosciences, University of the Ryukyus, Senbaru, Okinawa, Japan; 3 Laboratory of Global Animal Resource Science, Graduate School of Agricultural and Life Sciences, University of ... and presence of increasing concentrations of inhibitors for 10 days, and the number of molting larvae was determined. Molting was manifested by shedding of the L3 cuticle. Numbers of molted larvae ... molting process of A. suum L3 to L4 in vitro, virtually none had been characterized in relation to the actual mechanism of the molting process in this roundworm [56]. The basic structure of the...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: "The Structure and Process of Talking About Doing" pdf
... model of the role of point of view in problem solving. SUMMARY We have reported here a three pronged approach to the study of problem solving action and report: I) the collected of data ... solving and talk about problem solving, 2) development of a process model of these behaviors, and 3) use of coding techniques to extract traces of "critical phenomena" from the transcripts ... y0 w1 h1" alt="" "point of view" for a problem solver at each point in the problem solving from a record of the problem solving report and a record of moves made. Then, we use this...
Ngày tải lên: 21/02/2014, 20:20
Feedback Control of MEMS to Atoms potx
... is the subject of Chaps. 7 through 9. Position control of MEMS actuators is presented in Chap. 7, closed-loop operation of precision MEMS gyroscopes is covered in Chap. 8, and the control of particle ... agglomeration (merging of two particles into one), breakage (division of one particle to two) as well as nucleation of particles of size r ≥0 and particle feed and removal. The rate of change of the continuous-phase variables ... Multiscale Modeling and Control of HVOF Thermal Spray Coating Processes 2.3.1 Multiscale Modeling of Coating Microstructure The past decade has witnessed a shift of synthesis to processing in nanotechnology research,...
Ngày tải lên: 05/03/2014, 11:20
UK MARKET POTENTIAL FOR SLOVENIAN WINE - CASE STUDY OF THE INTERNATIONALISATION PROCESS OF THE SLOVENIAN WINE PRODUCER pdf
... and off-trade, the biggest of which was the takeover of Safeway by Morrisons in 2004 for £3 billion (Dennis, 2003, p.15). Waitrose, the supermarket arm of the John Lewis Partnership, offers ... reaches its optimal ripeness. Fast grape processing enables the set quality of wine, whilst the technology represents a major part of it. All of the processes are carefully controlled; documenting ... the biggest of which being that of market selection. Albaum, Duerr and Strandskov define export market selection as »the process of opportunity evaluation leading to the selection of foreign...
Ngày tải lên: 08/03/2014, 04:22
Báo cáo khoa học: "A NEW VIEW ON THE PROCESS OF TRANSLATION" pdf
... challenging aspect of this trans- lation process. The translation process is achieved by employing three principal levels of transfer, which are described in detail below. The product of this multi-level ... corresponding grammatical features of the Nigel grammar; e.g. ET-D active/passive to Nigel active- process/ passive -process. This type of transfer is very close to the idea of IS =~ IS transfer in ... the air of hav- ing a range of often tried and well known, but essen- tially unsatisfactory solutions. One whole class of questions relates to what should be preserved in a translation process, ...
Ngày tải lên: 09/03/2014, 01:20
the importance and impacts of costing method on the process of managerial decision making
... decision making process, all of expenses which are incurred in the accounting year of 2008-2009 will be analyzed. After introducing all of related information about costs of 40 Required of next ... 2009). But this does not mean all of information are useful for our decision making process. Overload of information, the motives and bias of providers, remoteness of information and complex transactions ... and impacts of accounting methods on managerial decision making process In order to find out the importance of different cost accounting method on the decision making process of managers,...
Ngày tải lên: 13/03/2014, 14:20
the importance and impacts ofcosting method on the process of managerial decision making
... “Pharmaceutical Company of Ha Tinh”. In 2001, implementation of the policy of the State and the People’s Committee of Ha Tinh Province 4726/QD-UB-DN the transformation of ownership pharmaceutical ... are the costs of activities performed on each individual unit of a product or service. Overtime, additional units of output produced will lead increase the cost of activities of running the ... effects of owning or leasing facilities? In order to answer theses and many other questions, managers must base on a lot of information systems processed by different sciences; one of them...
Ngày tải lên: 13/03/2014, 14:20
Báo cáo khoa học: Characterization of the dimerization process of a domain-swapped dimeric variant of human pancreatic ribonuclease pdf
... expression of the partial heat capacity of the protein relative to the heat capacity of the protein in the native state. Fig. 6. Analysis of the open interface of the dimeric form of PM8 (DPM8). ... Assessment of the degree of swapping of the N-terminal domain in PM8E103C. Results of SDS ⁄ PAGE analysis, under redu- cing conditions of the divinyl sulfone (DVS) cross-linking reaction of PM8E103C, ... independently of the swap- ping. To this end, the open interface of PM8 was engineered by introducing a Cys residue that would allow the binding of the protomers by means of a disulfide bridge. Analysis of...
Ngày tải lên: 16/03/2014, 13:20
MERCHANDISING – MODERN TECHNIQUE USED IN THE PROCESS OF GOODS SALES docx
... type of sale. Promoting the idea that merchandising is, first of all, “perfect knowledge of the sales point”, the French specialists consider that the rational use of each linear meter of furniture, ... Necessity. It refers to the decision of buying both of the consumer and of the seller. The buying decision of the seller is more difficult as a too small quantity of a certain product creates stock ... importance, in the key point of the sales (the shop), the issues and techniques of merchandising are the preoccupation of both traders and producers, who often support the efforts of the traders, by...
Ngày tải lên: 16/03/2014, 15:20
tem study on the formation process of tio2 nanotubes
... process and mechanism of TiO 2 nanotube is different from that of carbon nanotubes. Study on its formation process will helpful to understand the mechanism of formation of TiO 2 nanotubes ... formation process of TiO 2 nanotubes in the concentrated NaOH solution was investigated. The results indicated that TiO 2 nanotubes are formed in the stage of alkali treatment of polycry- ... 419 TEM Study on the Formation Process of TiO 2 Nanotubes Jing Wei ZHANG, Xin Yong GUO, Zhen Sheng JIN*, Shun Li ZHANG, Jing Fang ZHOU, Zhi Jun ZHANG* Lab of Special Functional Materials,...
Ngày tải lên: 20/03/2014, 13:08
Báo cáo khoa học: The oxidation process of Antarctic fish hemoglobins pot
... oxidation of AFHbs leads to the formation of a significant amount of a reversible hemichrome form. This finding, which is in line with a preliminary analysis of the oxidation process of Hb1Tn [8], ... determined the crystal structure of one of the intermediates of the oxidation process of this Hb [9]. This intermediate is characterized by a different binding state of the a and b chains. A CO molecule ... the T state form of HbTb was crystallized by Fermi and coworkers by simply lowering the pH of the carbomonoxy form of the protein to 6.0 [19]. In the early stages of the oxidation process (2–9 h,...
Ngày tải lên: 23/03/2014, 12:20
RISE OF THE AESTHETIC EXPERIENCE AND THE PROCESS OF GLOBALIZATION ppt
... technique of beautification, but represented the trigger for the legitimating of pervasive interference of all of the domains of rationality. The process of globalization causes the weakening of the ... aesthetic aspect of experience as about the experiential nature of the aesthetic. 1 RISE OF THE AESTHETIC EXPERIENCE AND THE PROCESS OF GLOBALIZATION ALEKSANDAR ČUČKOVIĆ Faculty of Economics, ... concepts of modern culture have been aestheticized, then we can find the reason for that process at the complexity of the term “aesthetic experience”. To understand the meaning of the process of...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: "THE PROCESS OF COMMUNICATION IN FACE TO FACE VS. COMPUTERIZED CONFERENCES; A CONTROL EXPERIMENT USING BALES INTERACTION PROCESS ANALYSIS" pot
... sympathy or offers of assistance; urging harmony and cooperation. These are all overt attempts to improve the solidarity of the group. Note that there is a significantly greater amount of "showing ... results of the 24 analyses of variance which examined observed differences between communi- cation modes for each of the two rases. The first two colu~us show the mean percentage of co~nunications ... Arono~Âch and Turoff, 1980) we show that the observed differences in interaction profiles are highly correlated w~h the abillty of a group to reach con- sensus and wirer the quali~y of group decision...
Ngày tải lên: 24/03/2014, 01:21
Báo cáo khoa học: "Lexical Selection in the Process of Language Generation" ppt
Ngày tải lên: 24/03/2014, 02:20
THE ENVIRONMENTALLY BENIGN PULPING PROCESS OF NON-WOOD FIBERS pptx
Ngày tải lên: 24/03/2014, 05:20
Báo cáo khoa học: Unfolding process of rusticyanin Evidence of protein aggregation ppt
Ngày tải lên: 30/03/2014, 15:20