extent of lymph node dissection in esophageal cancer

... be of interest [5,16,17] The decision-making should balance the possibility of gaining long-term survival against the risk of complications, worsening the outcome and decrease in quality of life ... covered within the limitations of the TNM-system and modifications have been suggested [23] Additional pathology information, including lymph node data, would be of interest when reporting from ... has the aim of identifying the patients with metastatic disease A positive finding has a major impact on the individual and does often lead to changes in the treatment strategy The findings are...

Ngày tải lên: 09/08/2014, 07:22

... Wolmark N: Sentinel -lymph- node resection compared with conventional axillary -lymph- node dissection in clinical node- negative patients with breast cancer: overall survival findings from NSABP ... formation included BMI, tumor size, number of involved nodes, total drainage before drain removal and time to drain removal [38] This is the first investigation in an American institution, evaluating ... following axillary dissection for breast cancer: risk factors and lack of influence of bovine thrombin J Surg Onc 1997, 64:27-31 Divino CM, Kuerer HM, Tartter PI: Drains prevent seromas following...

Ngày tải lên: 09/08/2014, 02:20

... probability of survival in invasive breast cancers [24] In conclusion, we found that the incidence of sentinel lymph node metastasis in cases of pure DCIS was 0.39% This incidence was lower than that in ... IDC-predominant invasive lesion with positive sentinel nodes, patients had dislocation of cancer cells along the biopsy scar Discussion In this study, we found that the incidence of sentinel lymph node ... encouraged the use of sentinel lymph node biopsy in pure DCIS, does not argue that sentinel lymph node biopsy should be carried out in all cases of pure DCIS [9] In their literature, only 22% of all DCIS...

Ngày tải lên: 09/08/2014, 03:21

... from the lymph node begins at the cortical sinus 21 1.7.4 Determinants of lymphocyte entry into cortical sinuses during lymph node egress 23 iii 1.7.5 Proper egress of lymphocytes ... adoptive transfer of lymphocytes 46 2.9 Quantification of S1P in skin draining lymph nodes, lymph fluid and plasma by mass spectrometry 48 2.9.1 Collection of lymph node, lymph and plasma ... positioning of the lymph nodes at various locations in the body Lymph nodes are positioned at the convergent points of afferent lymphatic vessels that drain antigen containing tissue fluid (lymph) ...

Ngày tải lên: 02/10/2015, 17:14

... para-aortic lymphadenectomy in cancer of the ovary Baillieres Clin Obstet Gynaecol 1989, 3(1):131-42 Chen SS, Lee L: Incidence of para-aortic and pelvic lymph node metastases in epithelial carcinoma of ... Y, Ebina Y, Watari H, Yamamoto R, Minakami H, Sakuragi N: Lymphatic mapping and sentinel node identification as related to the primary sites of lymph node metastasis in early stage ovarian cancer ... staging of ovarian cancer Gynecol Oncol 1995, 59(1):25-33 Carnino F, Fuda G, Ciccone G, Iskra L, Guercio E, Dadone D, Conte P: Significance of lymph node sampling in epithelial carcinoma of the...

Ngày tải lên: 09/08/2014, 03:23

... gastric cancer increases with the number of lymph nodes removed [7] Number of patients Lymph nodes Anastomosis Although previous studies have indicated that the lymphnode ratio (LNR), which is defined ... N-ratio in minimizing stage migration phenomenon in gastric cancer patients with insufficient number or level of lymph node retrieved: results from a Chinese mono-institutional study in 2159 ... potentially curative resection with examination of an inadequate number of lymph nodes Competing interests The author declares that she has no competing interests The following factors were correlated with...

Ngày tải lên: 09/08/2014, 04:21

... hand-stained by routine Hematoxylin and Eosin (H&E) staining The remaining tissue of each resulting 0.2 cm SLN tissue section, encompassing 75% of the thickness of that tissue, is then sent for routine ... 11/7/2002 in Helsinki, Finland This signifies that ILC makes up an astonishing 27.2% of all the breast cancers seen in Helsinki, Finland This is in stark contrast to the maximum of 10% to 15% of ILC ... analysis of all SLNs during breast cancer surgery in patients with ILC should remain the standard of care in order to reduce the risk of the need of a later, separate axillary lymph node dissection...

Ngày tải lên: 09/08/2014, 04:21

... role of sentinel lymph node biopsy procedure in a study where sentinel nodes, all of which were in the internal iliac lymph nodes of 15 out of 16 patients (93.7%) were identified by lymphoscintigraphy ... Sentinel node biopsy in early vulvar cancer Br J Cancer 2000, 82:295-299 Sliutz G, Reinthaller A, Lantzsch T, Mende T, Sinzinger H, Kainz C, Koelbl H: Lymphatic mapping of sentinel nodes in early ... one in the inguinal lymph nodes [34] In a study by O'Boyle et al 17% of the sentinel nodes were found in the common iliac area, 62% in the external iliac, 4% in the internal iliac, and 17% in...

Ngày tải lên: 09/08/2014, 07:21

... examined [37] In general, examination of an increased number of LNs results in greater chances of identifying LN metastases, thus minimizing under-staging [14,27,32-34] In our investigation of ... probability of finding positive LNs increased with increasing numbers of LNs examined In contrast, Bui et al [22] and Wong et al [15] found no substantial increase in LN positivity with increased ... AJ: Lymphatic mapping and focused analysis of sentinel lymph nodes upstage gastrointestinal neoplasms Arch Surg 2000, 135:926-932 45 Saha S, Nora D, Wong JH, Weise D: Sentinel lymph node mapping...

Ngày tải lên: 10/08/2014, 21:23

... sentinel lymph node biopsies for sarcomas and carcinomas in pediatric patients Cancer 2008, 1;112:2052-9 Maduekwe UN, Hornicek FJ, Springfield DS, et al: Role of sentinel lymph node biopsy in ... rate of lymph node metastasis in these tumours Previous studies have reported that the incidence of lymph node metastasis in such tumours is between 16.7 and 80% [5,10,11] A positive SLNB in these ... distribution of cases In patients with intermediate thickness melanoma, SLNB has become widely accepted as a minimally invasive method of staging the regional lymph nodes [14,15] When SLNB is performed in...

Ngày tải lên: 13/08/2014, 15:21

... routinely performed in all institutions Differences between CEA and Page of CK-19 qRT-PCR as detected in two cases reflect the heterogeneity of marker expression in lymph node metastases of CRC ... prototype of the RD-100i, 63 LN from CRC patients were investigated with both H&E staining and OSNA None of the LN was HE+/OSNA- and of the 63 LN were HE-/OSNA+, resulting in upstaging of two patients ... analysis of 3-4 LN within 30-40 minutes and 12 LN within hours For the reason that increasing numbers of investigated LN correlate with a more accurate tumour staging, high throughput methods are indispensable...

Ngày tải lên: 18/06/2014, 16:20

... and Treatment of Cancer QLQC30: a quality -of- life instrument for use in international clinical trials in oncology J Natl Cancer Inst 1993, 85(5):365-376 Bottomley A, Aaronson NK: International ... quality -of- life measurement in randomized clinical trials in breast cancer – taking stock Journal of the National Cancer Institute 2003, 95(4):263-281 Montazeri A: Health-related quality of life in ... domains of the EQ-5D have only three response levels, making it difficult to pick up small changes in health In addition, in the subgroup of patients reporting no change and the subgroup reporting...

Ngày tải lên: 18/06/2014, 19:20

... cutting area by root rot regardless of previous damage to stems caused by game The extent of root rot was even greater in two stands without deer barking damage, in the vicinity of the village of ... Class Extent of rot damage healthy, no signs of fungal attack on the stump cutting area small area of hard rot up to 10% of stump area, marginal soft rot up to 5% large hard rot, small soft rot ... salvage fellings was a windthrow in most cases and also bark beetles in small plots These spots were usually extended into Table Classification of stumps according to the degree of root rot damage...

Ngày tải lên: 07/08/2014, 10:21

... AM, Guindi M, Hornby J, Xu W, Ringash J, Keshavjee S, Chen E, Haider M, Darling G: Phase trial of preoperative irinotecan plus cisplatin and conformal radiotherapy, followed by surgery for esophageal ... Mayer R: Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781 J Clin Oncol 2008, 26(7):1086-92 ... alone in esophageal cancer patients: is it time for additional evidence? World Journal of Surgical Oncology 2011 9:41 Submit your next manuscript to BioMed Central and take full advantage of: •...

Ngày tải lên: 09/08/2014, 01:24

... and/ or field of surgery in the mediastinum) was not reached in both groups (Table 4) The role of CRT and surgery in Table 2: Final histopathological stages of tumors and lymph nodes in resected ... preoperative CRT causes down-staging in esophageal cancer In addition, we found that lymph node status is a predictor of outcome where patients with ≥ positive lymph nodes have poorest survival (Figure ... DeMeester TR: Predicting systemic disease in patients with esophageal cancer after esophagectomy: a multinational study on the significance of the number of involved lymph nodes Ann Surg 2008,...

Ngày tải lên: 09/08/2014, 03:21

... bacterial contamination by an aerobic and anaerobic bacteria are common causes of diarrhea after the radiation treatment of gynecological cancer Maintaining intestinal integrity during radiotherapy ... changes in intestinal flora mediated through fermented milk intake FEMS Immunol Med Microbiol 1994, 10:55-64 19 Salminen E, Elomaa I, Minkkinen J, Vapaatalo H, Salminen S: Preservation of intestinal ... shigella [11] In vitro studies have indicated that part of this effect may be due to lactobacillus strains [12-15] Since dysbiosis of the intestinal flora may be a promoting factor in radiotherapy-related...

Ngày tải lên: 09/08/2014, 08:23

... III rectal cancer [11], the role of adjuvant pelvic RT in rectal cancer with synchronous liver metastasis has not been defined In this study, we investigated the clinical implications of adjuvant ... consisted of irinotecan at 180 mg/m2 on day one with leucovorin at 400 mg/m administered as a two hour infusion before 5-FU at 400 mg/m2 being administered as an intravenous bolus injection, ... whole pelvis including the tumor bed and pelvic lymph nodes and a boost dose of to 12.6 Gy was delivered to the tumor bed in a 1.8 Gy daily fraction Boost volume consisted of areas of initial tumor,...

Ngày tải lên: 09/08/2014, 09:20

... illustration of the protein with important areas such as substrate binding domains, Leucine zipper, ATP-binding domains, FAT domain and PI3K domain [17] together with exonic information (The size of the ... PI3K domain, substrate binding domains and ATPbinding domains, is illustrated in Figure Single marker associations Risk for developing breast cancer The association between any variant in the ATM ... both in monomeric (active) and dimeric (inactive) state [16] The protein contains several important domains such as 1) the C-terminal protein kinase domain (PI3K-domain), 2) the substrate binding...

Ngày tải lên: 09/08/2014, 10:21

... for the influence of stage of esophageal cancer, the average hand-grip strength was similar in patients having early and advanced esophageal cancer. (p value is 0.961) Advanced esophageal cancer ... Respiratory failure requiring re-intubation was found in 12 patients, pneumonia in patients, pleural effusion requiring tube drainage in 5, anastomotic leak in and other conditions in patients Surgical ... adenocarcinoma The locations included patients in the upper third, 31 patients in the middle third and 14 in the lower third All underwent surgery for cure intent, including en-bloc resection of the...

Ngày tải lên: 10/08/2014, 09:22

... regulating the activities of phosphotyrosine phosphatases [23] In the current study, we examined XAF1 mRNA and protein expression in four cell lines, and determined regulatory effects of somatostatin ... somatostatin and Octreotide in prostate cancer cell lines To examine the regulatory effects of somatostatin and Octreotide on XAF1 mRNA and protein expression, prostate cancer cell lines (LNCaP, ... features of prostate cancer progression from early stages to androgen independent stages, could mimic the development of prostate cancer clinically Understanding the regulating effects of XAF1 during...

Ngày tải lên: 10/08/2014, 10:20