expression of target genes is uncorrelated to that of bystanders

Báo cáo y học: " Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during " pps

Báo cáo y học: " Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during " pps

Ngày tải lên : 14/08/2014, 21:20
... regulation of miRNA expression during development The number of sequence reads for a particular miRNA is known to be proportional to the molecular abundance of that species [33] Thus, the number of sequence ... the seed sequence common to the bantam miRNA family, which is known to function in apoptosis [41] Further, we found that this novel miRNA is clustered on chromosome IV together with another four ... CAU C U U U U mir-2217 Figure Validation of the expression of novel miRNAs Validation of the expression of novel miRNAs (a) Validation of the expression of novel miRNAs by RT-PCR Error bars represent...
  • 15
  • 279
  • 0
Báo cáo Y học: Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues docx

Báo cáo Y học: Expression of the aspartate/glutamate mitochondrial carriers aralar1 and citrin during development and in adult rat tissues docx

Ngày tải lên : 24/03/2014, 04:21
... the loss of citrin in the kidney of patients with CTLN2 This raises a general question of whether the two isoforms are expressed in the same tissues and cell types and whether these isoforms play ... indicate that the two isoforms are widely expressed throughout embryogenesis with a dynamic expression pattern The characteristic expression of aralar1 in skeletal muscle and citrin in liver is only ... Therefore, the expression pattern of both citrin and aralar1 in rat is consistent with that described for human and mouse tissues [6,8,18] The data on the mRNA distribution of the AGC isoforms were...
  • 8
  • 432
  • 0
Báo cáo y học: "Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthriti" pptx

Báo cáo y học: "Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthriti" pptx

Ngày tải lên : 09/08/2014, 07:20
... which is missing in OA tissue This is why this smear is not found in Figure 2, lane 2, where aggrecan is lost (M Paulsson, personal communication) With the help of light microscopic immunohistochemistry, ... preparation of tissues The abortion material and the cartilage specimens were transported to the laboratory in histidine-tryptophane-ketoglutarate solution at 4°C to ensure good preservation of the tissues ... articular cartilage of late-stage osteoarthritis Osteoarthritis Cartilage 2001, 9:654-663 34 Tesche F, Miosge N: New aspects of the pathogenesis of osteoarthritis: the role of fibroblast-like...
  • 10
  • 480
  • 0
Báo cáo khoa học: Oxidative stress and apoptotic events during thermal stress in the symbiotic sea anemone, Anemonia viridis potx

Báo cáo khoa học: Oxidative stress and apoptotic events during thermal stress in the symbiotic sea anemone, Anemonia viridis potx

Ngày tải lên : 30/03/2014, 10:20
... involved in the initiation phase of apoptosis contributing to cell death signaling [27] Programmed cell death is known to model tissue during embryogenesis, to remove damaged cells, protect against ... activity was totally abolished The induction of an apoptosis-like phenomenon in A viridis subjected to a heat stress was confirmed by the analysis of DNA fragmentation in anemone tissues, using ... bleaching in animal tissue of A viridis The occurrence of oxidative stress in the animal tissue (ectoderm and gastroderm) and freshly isolated zooxanthellae of A viridis was monitored during heat...
  • 13
  • 415
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 2 docx

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 2 docx

Ngày tải lên : 21/06/2014, 10:20
... polarization distortions and is an isotropic thermal lens A contribution to this lens is made by the temperature dependence of the refraction index and “isotropic” part of the photoelastic effect ... Fig Cross-section of magneto-optical crystal: r, φ are polar coordinates; θ is angle of inclination of the crystallographic axis; Ψ is angle of inclination of eigen polarization of thermally induced ... Γ(r,φ) is Γ(r ,ϕ ) = EC x / EC 2 (13) , where EС is the complex amplitude of the field at point С− Of major interest is the integral depolarization γ (the isolation degree of the FI is 1/γ) that is...
  • 40
  • 296
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 4 doc

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 4 doc

Ngày tải lên : 21/06/2014, 10:20
... of pump beam passes through the crystal can be increased to and even more, if to use a lens with appropriate focal distance in front of Yb:YAG crystal Results of comparison of effectiveness of ... also found that switching of the laser from CW regime to Q-switched regime was accompanied as well by misalignment of laser resonator because of appearance of optical wedge in acousto-optical ... easy way to shorten the blind area is to broaden the receiver’s field of view (FOV), but this increases the background noise and decrease the dynamic range of lidar echo Another method is to set...
  • 40
  • 408
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 6 pot

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 6 pot

Ngày tải lên : 21/06/2014, 10:20
... number of laser pulses Then it is understood that higher total ignition energy is necessary for a leaner mixture One hundred percent ignition is accomplished in the fuel-lean mixture of A/F of 17.2 ... Plaza Tokai (2006-2009) We thank Dr Fujikawa of Toyota Central R&D Labs., Inc for technical discussion of combustion and Mr Mizutani of the equipment development division of IMS for fabrication of ... (5): it is assumed to have a flat-top profile in the vertical direction while it has a smooth symmetric profile in the horizontal ξ-direction, with a peak on axis This is a consequence of the...
  • 40
  • 239
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 10 pdf

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 10 pdf

Ngày tải lên : 21/06/2014, 10:20
... about 40 to 100 This order of magnitude is due to the hypthesis that the gap region is the same and that the pixel edges are perfectly sharp The smoothing of the phase between pixels has to be considered ... size is too big, the blurring of the mask will give rise to substantial diffraction effects As the spatial profile of a wavelength on the mask is the Fourier transform of the spatial profile ... dimensions Due to this coupling, no simple expression of the pulse shaper response function H(ω) can be given without the strong hypothesis that this effect is negligeable To illustrate this effect,...
  • 40
  • 191
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 11 pptx

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 11 pptx

Ngày tải lên : 21/06/2014, 10:20
... arm of each of the two collimators is equal to the output arm of each of the two condensers With reference to Fig 10, the term "input arm" refers to the two collimators and indicates the distance ... interval With respect to the off-plane mount, the efficiency of the same grating is lower by a factor two to three This confirms the advantage of the off-plane mount in terms of high throughput ... atoms, but not because of the increase of the number of the gas atoms Gas atoms moved from the position of higher temperature to that of lower temperature, which resulted in that the gas density...
  • 40
  • 320
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 12 pptx

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 12 pptx

Ngày tải lên : 21/06/2014, 10:20
... potential of vanadium is 14.65 eV, but the cut-off is at the 71st harmonic (11.20 nm wavelength), with photon energy of 110 eV That is, the second ionization potential of vanadium is lower than that of ... in the spectrum correspond to the cutoff of trajectory pairs C and D Why does not a step (cutoff) for pair B appear? This is related to the field strength at time of ionization, indicated with ... cut-off energy of vanadium is higher than that of silver The estimated maximum cut-off energy of vanadium was 85.6 eV by using the cut-off rule equation and assuming that the Up is the same as that...
  • 40
  • 224
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 13 pptx

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 13 pptx

Ngày tải lên : 21/06/2014, 10:20
... Z-axis is the axis of propagation of the driving beam, and the X-axis is the axis vertical to the Z-axis This axis is defined by the walk-off direction of the second harmonic with respect to the ... fabricated the target so that a slab silver target was next to the nanoparticle target, with the two target surfaces at the same height This target was placed on to the target holder, so that they ... the polarization of the main pulse This also allows one to distinguish the plasma emission from the HHG HHG is highly sensitive to laser polarization, since the trajectories of the recolliding...
  • 40
  • 253
  • 0
Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 14 pdf

Advances in Solid-State Lasers: Development and Applicationsduration and in the end limits Part 14 pdf

Ngày tải lên : 21/06/2014, 10:20
... keV of Fig Because both of the photon energy E and the total radiated energy I is proportional to γ , the number of the radiated photons I / E is independent of γ For an electron bunch of nC ... Scattering: Toward Intense Attosecond Pulse 519 3.1 Solid target In the case of a solid target for distributed electrons (Lee et al, 2005), the time intervals that radiations take to a detector can ... Relativistic Nonlinear Thomson Scattering: Toward Intense Attosecond Pulse 523 Eq (26) also shows why the direction of the beam velocity ( θ b ) is set to be different from the axis of the beam distribution...
  • 40
  • 217
  • 0
Báo cáo y học: " The angiogenic factor midkine is regulated by dexamethasone and retinoic acid during alveolarization and in alveolar epithelial cells" potx

Báo cáo y học: " The angiogenic factor midkine is regulated by dexamethasone and retinoic acid during alveolarization and in alveolar epithelial cells" potx

Ngày tải lên : 12/08/2014, 14:20
... purpose of this study was to examine regulation of MK expression by GC and RA during postnatal alveolar formation in neonatal rat pups We hypothesized that MK expression in both lungs and in isolated ... percent of control RNA Isolation Total RNA was obtained from snap-frozen tissue maintained on ice during isolation Tissue (~250 mg wet weight) was mechanically homogenized and total RNA was isolated ... normalized to percent of control Statistical Analysis Statistical comparisons between groups were carried out using ANOVA with Fisher's exact test and Bonferroni correction for individual comparisons...
  • 10
  • 231
  • 0
Báo cáo khoa học: "Transfer of immunoglobulins through the mammary endothelium and epithelium and in the local lymph node of cows during the initial response after intramammary challenge with E. coli endotoxin" ppt

Báo cáo khoa học: "Transfer of immunoglobulins through the mammary endothelium and epithelium and in the local lymph node of cows during the initial response after intramammary challenge with E. coli endotoxin" ppt

Ngày tải lên : 12/08/2014, 18:22
... amounts of free IgG2 was reduced due to enhanced binding to IgG2 specific surface receptors of the neutrophils [40] The relative transfer of IgG2 from tissue into milk was almost identical to that of ... inflammatory reaction endotoxin from Escherichia coli was infused into the mammary gland Endotoxin is considered the key factor in E coli mastitis and intramammary infusion of purified endotoxin is ... lymph node (Fig 2B) This indicates a factor that is limiting the diffusion of IgM compared to that of BSA A plausible explanation is that the large size of the Ig M molecule makes passage through...
  • 10
  • 332
  • 0
Assessment of testis development during induced spermatogenesis in the european eel anguilla anguilla

Assessment of testis development during induced spermatogenesis in the european eel anguilla anguilla

Ngày tải lên : 04/09/2015, 12:44
... novel quantification of testis development Eels in the experiments were sacrificed weekly and testis tissue was sampled for histological analysis of spermatogenesis Testis development was followed ... progression of spermatogenesis and the duration of the spermiation period The objective of the present study was to assess testis development in European eels during induced spermatogenesis, including ... The GSI of males that showed signs of depletion dropped rapidly, whereas the gradual decrease in SMI indicated that spermatogenesis FIGURE Photomicrographs (scale bar = 100 μm) of three histological...
  • 14
  • 377
  • 0
Tài liệu HEALTH CONTINUUM AND DATA EXCHANGE IN BELGIUM AND IN THE NETHERLANDS docx

Tài liệu HEALTH CONTINUUM AND DATA EXCHANGE IN BELGIUM AND IN THE NETHERLANDS docx

Ngày tải lên : 16/02/2014, 20:20
... prescription This is no longer efficient An analysis of the activities of this kind of hospitals shows that only 24% of the time is dedicated to the basic hospital function: patient care and stay 76% of ... Netherlands Abstract The goal of this paper is to contribute to the improvement of the quality of care For physicians, it is a problem that they are often not aware of gaps in their knowledge and ... management It is only genuine to propose the registration of new data when the data of the existing NMDS or other related data sets seem insufficient to update existing indicators or to develop...
  • 136
  • 563
  • 0
Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc

Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc

Ngày tải lên : 19/02/2014, 12:20
... summation is carried out over the range of appreciable values of F The values of center of spectral mass of tryptophan were converted into degree of denaturation/dissociation (ap), according to the ... promote significant binding of bis-ANS to any of the particles, with the exception of T45S, which bound a small amount of bis-ANS, increasing, by twofold, the emission of the probe (Fig 7B) M88V ... analysis suggests that the hydroxyl group of Thr45 makes H-bonds with N6 and N7 of A-4 [47] Moreover, the lack of binding of bis-ANS in this mutant, following treatment with urea, suggests that...
  • 11
  • 609
  • 0
Health Continuum and Data Exchange in Belgium and in the Netherlands doc

Health Continuum and Data Exchange in Belgium and in the Netherlands doc

Ngày tải lên : 05/03/2014, 23:20
... prescription This is no longer efficient An analysis of the activities of this kind of hospitals shows that only 24% of the time is dedicated to the basic hospital function: patient care and stay 76% of ... Netherlands Abstract The goal of this paper is to contribute to the improvement of the quality of care For physicians, it is a problem that they are often not aware of gaps in their knowledge and ... management It is only genuine to propose the registration of new data when the data of the existing NMDS or other related data sets seem insufficient to update existing indicators or to develop...
  • 136
  • 592
  • 0