exercise therapy for the overweight adult
Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier
... is the major contributor for the clearance of NPs, thus the reducing rate of MPS uptake could be considered as the best strategy for prolonging the circulation of NPs (Li & Huang, 2008) Therefore, ... added to the above solution, and the mixture was subsequently stirred at 54°C for 48 h The reactant was precipitated with distilled water, and then washed with distilled water and methanol The solid ... exhibit the longer blood circulation time than free EPI in vivo 556 H.-B Tang et al therefore, a steric stabilization may occur and provide the stability of the PANs It may also be important information...
- 7
- 391
- 0
Tài liệu Copper and Fiber Labeling Software and Labeling Sheets docx
... contains labels for the front and back of the hinged label SH ADCLS-TFP1RUA Adhesive label for ADC’s 2RU TFP Fiber Panel Each label sheet contains labels for the front and back of the hinged label ... ADCLS-TFP2RUA Adhesive label for ADC’s 5RU TFP Fiber Panel Each label sheet contains labels for the front and back of the hinged label SH ADCLS-TFP5RUA 3/08 • 106049AE SH Adhesive label for ADC’s patch cords ... sheet for left side of block SH ADCLS-NGF192LCAL Adhesive label for ADC’s 192 Fiber NGF Blocks Each label sheet contains label sheet for right side of block SH ADCLS-NGF192LCAR Adhesive label for...
- 4
- 534
- 0
Tài liệu Stability and Control of Large-Scale Dynamical Systems pptx
... whereas Matrosov allows for the components to be dened in the entire state space The latter formulation allows for the components of the vector Lyapunov functions to capture the whole state space ... subsystems The behavior of the aggregate or composite (i.e., large-scale) system can then be predicted from the behaviors of the individual subsystems and their interconnections The need for decentralized ... subsystems The behavior and properties of the aggregate large-scale system can then be deduced from the behaviors of the individual subsystems and their interconnections Often the need for such...
- 389
- 723
- 0
Tài liệu The Decline of Traditional Banking: Implications for Financial Stability and Regulatory Policy doc
... terest income and therefore overstates the decline in the profitability of traditional banking Another indicator of the decline in the profitability of traditional banking is the fall in the ratio of ... been conducted by the Bank for International Settlements (the “Promisel Report”), the Bank of England, the Group of Thirty, the Office of the U.S Comptroller of the Currency, the Commodity Futures ... Can these activities be effectively regulated? The challenges posed by these questions are no different for derivatives than they are for other banking activities IMPLICATIONS FOR POLICY The...
- 21
- 552
- 0
Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
... shift of the C-terminal helix away from the helices that contain the mutations, with the ˚ largest movements on the scale of A The motion is rigidbody, in the sense that the helices themselves ... you are selecting for, and the degree to which these correspond is always up for debate On the other hand, our exploration of protein sequence space is desperately meagre at the moment, and methods ... insufficient for identification of the vanishingly small amounts of selected proteins from a library The best practical solution conceived to date is the linkage of nucleic acid encoding the protein to the...
- 14
- 584
- 0
Đề tài " Stability and instability of the Cauchy horizon for the spherically symmetric Einstein-Maxwell-scalar field equations " doc
... equations The reader can recover the full result of the proposition from the estimates for ν in Section For the slighter weaker result then, by virtue of the co-area formula, it suffices to bound the ... uniquely determines the solution The conditions for predictability are then related to the behavior of the unique solution of the initial value problem on the boundary of this region In the following ... arguments, a local existence theorem, and the domain of dependence theorem for the function space defined by the above norm guarantee the existence of a unique solution to the initial value problem...
- 55
- 318
- 0
Báo cáo khoa học: Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding pot
... both their thermodynamic and kinetic stability [10,12], suggesting the involvement of the cysteine pair in the thermal stabilization of both enzymes In the present study, we demonstrate that the ... glycine, respectively) Therefore, the stability imparted to the native protein structure could be almost marginal On the basis of these observations, it is possible to hypothesize that CXC plays ... damage of the other disulfide bonds of the protein To demonstrate the active role of CXC motif in the oxidative folding process, we carried out the unfolding of SsMTAPII, PfPNP and their CXClacking...
- 7
- 496
- 0
Báo cáo khoa học: Effect of flanking bases on quadruplex stability and Watson–Crick duplex competition pptx
... using the nearest-neighbor method The DSITC for duplex formation decreased with the increase in the number of anking bases from to However, there was deviation from the decreasing DSITC values for ... to preformed quadruplex DHITC is the enthalpy change and DSITC is the entropy change for duplex formation DGITC is the free energy change for duplex formation and was determined using the relationship ... sequences at both their ends The study shows that the presence of anking bases affects the thermodynamic stability of the G-quadruplex With an increase in the ank length, the increase in the more favorable...
- 13
- 638
- 0
Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc
... 3) indicates that the free-energy profile for the thermostable protein would be a flattened version of that for the protein from the mesophile Thus, the thermostable protein would have a more shallow ... been reported in the literature For each protein, the source organism, its maximum growth temperature, the fold of the protein, the presence of cofactors, the oligomeric state, and the protein databank ... contribute to the high stability of AaFd1 Like the A aeolicus Fd proteins, the [4Fe)4S] Fd from the hyperthermophile, Thermotoga maritima (TmFd) and the di-cluster [3Fe)4S] ⁄ [4Fe)4S] Fd from hyperthermophilic...
- 11
- 507
- 0
Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf
... affect the intrinsic fluorescence of the DK9 variant, the higher the surface exposure and flexibility of their side-chains to the solvent the smaller the intrinsic fluorescence of the enzyme The smaller ... and +9% for WT and DK9 mutant thrombin, respectively These results suggest that the Na+-binding loop in the K9-deleted mutant retains the intrinsic affinity for the cation, although the conformational ... expresses the acylation rate By contrast, the decrease in the DK9 Km value is consistent with better accommodation of the substrate into the catalytic pocket of the unprotonated form of the mutant,...
- 11
- 553
- 0
Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx
... representing the change in activation enthalpy, heat capacity and entropy of formation of the TSE for folding (U-à) Reported errors reflect the quality of the nonlinear least squares fit to the experimental ... are clearly evident in the NOESY data for WT*, P37A, P38A and A37A38 Further, Ile36 NH has the characteristic upfield shift that confirms that the C terminus of the helix and the C-capping motif are ... that the Ala38 methyl group occupies the same hydrophobic pocket as the side chain of Pro38 Modelling the structure with Ala substitutions imposed on the backbone conformation of WT* shows that the...
- 11
- 549
- 0
Báo cáo Y học: Processing, stability, and kinetic parameters of C5a peptidase from Streptococcus pyogenes pptx
... kV in the linear mode for proteins and 25 kV in the reflector mode for peptides In general, 200 single spectra were accumulated for improving the signal/noise ratio and analyzed by use of the DATA ... investigate the kinetic parameters for peptide cleavage by C5a peptidase, we synthesized two derivatives of the 19-mer parent peptide These include the 16-mer SQLRANISHKDMQLGR and the 12-mer VVASQLR ... and selected for the presence of the desired mutation by loss of a SpeI restriction site The presence of SerfiAla mutation at position 512 was also confirmed by sequencing the scpA gene The resultant...
- 13
- 487
- 0
FINANCIAL LIBERALIZATION, MACROECONOMIC (IN)-STABILITY, AND PATTERNS OF DISTRIBUTION pptx
... target either the nominal exchange rate or the interest rate, leaving the determination of the other to the interplay of the market forces The overwhelming evidence accumulated from the developing ... and the monetary base was to be totally dependent on the purchases of foreign exchange by the CB Together with lower limits for the net international reserves and upper limits for PSBR as performance ... rates for the two indices at the end of 2000 Furthermore it programmed a 20% increase in the nominal TL price of a basket of 1US$+0.77 Euro Upper limits for the net domestic assets of the Central...
- 73
- 449
- 0
Báo cáo khoa học: Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein potx
... distinguishes them from their mesophilic and thermophilic counterparts is their lower thermal stability [66] This could therefore be one explanation for the reduced stability that we observed for sbTTR ... was the low thermostability of the ecTRP protein, with a Tm value approximately 26 °C below the values for both sbTTR and hTTR (Fig 7) The inability of ecTRP to form fibrils at low pH can therefore ... respectively, for 72 h The fibril heights were estimated to be 2.8 nm for hTTR, 3.5 nm for sbTTR, and 4.0 nm for ecTRP The white scale bar is 500 nm (B) Left: EM image of ecTRP from the same...
- 13
- 419
- 0
Báo cáo khoa học: Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2 pdf
... of the tetramers in the unit cell are related to each other by this vector This was confirmed by the solved structure, in which, for each of the four tetramers in the unit cell, there is another ... sites The reasons for the concentration of the modifications to these areas in 3D space are currently not known, but they could include the accessibility of these areas towards modifications, their ... mgÆmL)1, and the crystal structure values for Rg, excluded volume and Dmax are as given by CRYSOL The theoretical I(0) was calculated for the crystal structure based on the I(0) of BSA The SAXS excluded...
- 14
- 431
- 0
power system stability and control chuong (1)
... sags 10%, then the cause of the sag is on the load side of the current monitor point If the current increases or decreases 10–20% during a 10% voltage sag, then the cause of the sag is on the source ... voltage waveforms Some machines compare portions of successive waveforms, and capture the waveform if there is a significant deviation in any portion of the waveform Others capture waveforms if there ... significant clues to the source of the event For example, if the event is a voltage sag, the minimum voltage may be the same for an event caused by a distant fault on the utility system, and for a nearby...
- 8
- 522
- 3
power system stability and control chuong (2)
... publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use No part of this book ... together the core of knowledge from all of the many topics encompassed by the field The chapters are written primarily for the electric power engineering professional who is seeking factual information, ... accomplished the goals that were set Their contributions are, of course, most key to the success of the work I gratefully acknowledge their outstanding efforts Likewise, the expertise and dedication of the...
- 14
- 498
- 5
power system stability and control chuong (3)
... turbines, but when the money ran out, they were looking for other research projects The government funded a number of test turbines, from the 100 kW MOD-0 to the 2500 kW MOD-2 These ran for brief periods ... write a check to the owner at the end of the month, rather than the other way around The utilities not like this arrangement They want to buy at wholesale and sell at retail They feel it is unfair ... consumption by the home and the other energy production by the turbine The owner would pay the regular retail rate, and the utility would pay their estimate of avoided cost, usually the fuel cost...
- 10
- 611
- 3
power system stability and control chuong (4)
... cathode through the outer circuit At the cathode the oxygen molecule interacts with the hydrogen ion and the electron from the outside circuit to form water The performance of the PEM fuel cell ... Only then can each H atom release an electron to form a hydrogen ion (Hþ) which travels to the cathode through the electrolyte At the same time, the free electron travels from the anode to the ... in the form of usable steam or hot water For a power plant, the number of fuel cells can vary from several hundred (for a 40-kW plant) to several thousand (for a multi-megawatt plant) In the...
- 8
- 328
- 0
Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25