exercise muscle damage and oxidative stress

... (HPLC) system to andrographolide (AGP), neoandrographolide (NAG), and 14-deoxy-11, 12-didehydroandrographolide (DDAG) contents, and the standardised extract was termed APAE and used for the study ... cytokines (TNF-a, IL-1b, and IL-6) and production of ROS and TBARS and enhanced the activities of AChE and BChE Furthermore, APAE enhanced the decrease in the levels and expression of hippocampal ... upregulation of these oxidative stress markers (Fig 5A and B) and improved learning and memory compared to LPS treatment alone Evidence suggests that upregulation of free radicals and other ROS with

Ngày tải lên: 13/01/2020, 04:28

... vitamin C and vitamin E on attenuating exercise-induced muscle damage and oxidative cellular damage in response to various types of exercise, such as prolonged exercise, high-intensity exercise, and ... vitamin C and e supplementation on muscle damage and oxidative stress in female athletes: a clinical trial Int J Prev Med 2013; 4: S16-23 51 Urso ML, Clarkson PM Oxidative stress, exercise, and antioxidant ... to a reduced state, and thereby suppress oxidative damage [1] The addition of vitamin E into dietary food has been demonstrated to protect against oxidative stress and muscle damage resulting from

Ngày tải lên: 15/01/2020, 07:34

... transformation (Figures and 5, and Additional files and 3), we used ANOVA The ANOVA (Figure 5A and Additional file 3) and repeated-measures ANOVA analyses (Figures and 5B, and Additional file 1) ... dehydration and to drastic oxidative stress conditions The single overexpression of HaHSFA4a, in the 35S:A4a seedlings, failed to induce tolerance to the severe dehydration and the drastic oxidative stress ... longevity and in synergistic effects on seedling tolerance to severe dehydration and oxidative stress José-María Personat, Javier Tejedor-Cano, Pilar Prieto-Dapena, Concepción Almoguera and Juan

Ngày tải lên: 27/05/2020, 01:25

... generated in saltaffected plant tissues in both roots and leaves [45,46], and the causal link between salinity and oxidative stress signalling and reactive species detoxification is becoming evident ... relative contribution of ionic, osmotic and oxidative stress components towards overall salinity stress tolerance in this species, both at the whole-plant and cellular levels In addition, transcriptional ... pH and K+ standards before and after use The electrodes were mounted on a 3D-micromanipulator (MMT-5, Narishige, Tokyo, Japan) and the tips of the electrodes were drawn close to each other and

Ngày tải lên: 27/05/2020, 01:49

... Phospho-aspirin-2 induces oxidative stress in TNBC A: PA-2 induced RONS in MDA-MB-231 and BT-20 cells after 1h treatment, as determined by DCFDA, DHE and MitoSOX Red staining and flow cytometry B: ... The induction of oxidative stress plays a key role in the anticancer effect of structurally related phosphoNSAIDs [9,42] PA-2 induces oxidative stress in TNBC cells in culture and in xenografts ... possesses chemotherapeutic and chemopreventive efficacy against TNBC in preclinical models, and establishes inhibition of EGFR, acetylation of p53 and induction of oxidative stress as critical mediators

Ngày tải lên: 05/11/2020, 01:26

... indicators measured by spirometry and flow-volume curve, and biomarkers of inflammation, allergy, and oxidative stress, between tone-handling workers and non-toner-handling workers We did not observe ... tests and the values of biomarkers in both models and In model 1, we treated tonerhandling work, the survey year, and the interaction between toner-handling work and survey year as fixed effects and ... low-concentration toner exposure group, and non-toner-handling group We also adapted a higher-fit model of the random intercept model and the random intercept and slope model for model If any significant

Ngày tải lên: 06/05/2021, 15:31

... modeling of health space based on metabolic stress and oxidative stress scores Cheolgyun Park1†, Youjin Kim2†, Chanhee Lee3, Ji Yeon Kim4, Oran Kwon2* and Taesung Park1,3*  Abstract  Background:  ... scores of metabolic stress and of oxidative stress Methods:  These scores were derived from three statistical models: logistic regression model, logistic mixed effect model, and proportional odds ... in two-dimensional space where the two axes represent oxidation and metabolism stress scores We choose oxidative and metabolic stress because they are the main processes in which the imbalance

Ngày tải lên: 31/10/2022, 04:00

... Bandouchova et al Acta Veterinaria Scandinavica 2011, 53:2 http://www.actavetscand.com/content/53/1/2 RESEARCH Open Access Biochemical responses and oxidative stress in Francisella ... such as uric and ascorbic acids and glutathione were assayed using square wave voltammetry and the results Bandouchova et al Acta Veterinaria Scandinavica 2011, 53:2 http://www.actavetscand.com/content/53/1/2 ... mice and common voles the LD 50 was calculated to be about and 38 CFU, respectively [19] Similar results of lower Bandouchova et al Acta Veterinaria Scandinavica 2011, 53:2 http://www.actavetscand.com/content/53/1/2

Ngày tải lên: 01/11/2022, 08:52

... metabolism, oxidative stress, and aging (Laoukili et al., 2007; Tuteja and Kaestner, 2007a; van der Horst and Burgering, 2007; Fu and Tindall, 2008; Hannenhalli and Kaestner, 2009; Kloet and Burgering, ... involved in the activation of genes that regulate oxidative stress resistance (Rodriguez-Colman et al., 2010), and induction of oxidative stress by H2 O2 and MD resulted in Fkhdependent cell cycle arrest ... transcription factors and Sir2 in response to oxidative stress Of note, a microarray analysis of oxidant-treated FKH1 and FKH2 deficient cells identified alterations in cell cycle and stress response

Ngày tải lên: 02/11/2022, 10:46

... of hypoxia and oxidative stress with mitochondrial dysfunction and cell damage in both dams and offspring, and upregulated inflammatory markers in offspring, which may render SE dams and their ... brain inflammation and oxidative stress Therefore, we hypothesise that there may be a causal link between cigarette smoke exposure (SE), increased inflammation, oxidative stress and mitochondrial ... common in both developed and developing countries3,4, and ~20–45% women smoke during pregnancy in Europe, Australia, South America, and South Africa3–5 Smoking and second hand smoking in pregnant

Ngày tải lên: 04/12/2022, 14:50

... receptor, and common processes are highlighted with the same color Both LXR and RXR agonism altered cholesterol biosynthetic processes, while LXR and PPARγ regulated triglyceride metabolism, and RXR and ... of Runx2 Increased expression of oxidative stress markers in osteoarthritic cartilage Txnip plays an important regulatory role in mediating oxidative stress and inflammation in a number of tissues ... PPARδ, and RXR, while four genes are commonly regulated by LXR, PPARδ, and PPAR γ Three genes are regulated by LXR, PPARγ, and RXR, and two genes are commonly regulated by PPARδ, PPARγ, and RXR

Ngày tải lên: 04/12/2022, 15:53

... beneficial effect on the prevention and treatment of peripheral neuropathy induced by oxidative stress Key words: Baicalein; Schwann cells; oxidative stress; DNA damage; apoptosis; Nrf2/HO-1 Introduction ... cells from DNA damage and apoptosis by oxidative stress are not yet clear Therefore, in this study, we investigated the protective effect of baicalein on cellular injury by oxidative stress using ... Nrf2-dependent HO-1 by baicalein in various cell and animal models plays an important role in the inhibition of DNA damage and/or apoptosis by oxidative stress [26,28-31] However, the potential mechanisms

Ngày tải lên: 15/01/2020, 22:53

... peroxidation and H2O2 and NO levels as a marker of oxidative and nitrosative stress were estimated in testicular tissue Previous studies authenticated the prominence of oxidative stress in the ... antioxidants and oxidative stress markers in testis Development of testicular impairment followed by CP exposure is mainly ascribed to free radical intervened oxidative distress and attenuation ... protects against cisplatin-induced DNA damage, oxidative stress and testicular injuries in adult male rats Tayyaba Afsar1, Suhail Razak2,3*, Muhammad Rashid khan1 and Ali Almajwal3 Abstract Background:

Ngày tải lên: 23/07/2020, 23:46

... glutathione and NADPH [7] Msn2 and Msn4 activate genes whose promoters contain the stress responsive element (STRE: CCCCT) after several environmental challenges, including oxidative stress Despite ... mitochondria 810 to oxidative stress, we evaluated H2O2 sensitivity of deletion mutants for the regulators most frequently associated with oxidative stress response: Yap1, Skn7, Msn2 and Msn4 Single ... involved in conveying an oxidative stress signal to the transcription factor Pos9 (Skn7) Mol Gen Genet 262, 437–447 Costa V & Moradas-Ferreira P (2001) Oxidative stress and signal transduction

Ngày tải lên: 16/03/2014, 14:20

... PFMT and ES (Table 6), two studies on PFMT and VW (Table 7), three studies on PFMT with BF and ES (Table 8), one study on PFMT, BF and VW, (Table 9), and one study on PFMT combined with ES, BF and ... objective and quality of life measures PFMT = pelvic floor muscle training PFMT+BF = pelvic floor muscle training with biofeedback PFMT+BF+ES = pelvic floor muscle training with biofeedback and electrical ... muscle training and electrical stimulation PFMT+VW = pelvic floor muscle training with vaginal weights PFMT +BF+ES+VW = pelvic floor muscle training with biofeedback, electrical stimulation and

Ngày tải lên: 28/03/2014, 14:20

... in isolated heart preparations [195] and subsequently shown to be associated with tissue damage in this and other organs, including the kidney and skeletal muscle [196,197], but not in others, ... Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury Cell Calcium 36, 257–264 441 Ca2+, mitochondria, ROS in neuronal disease C Chinopoulos and V Adam-Vizi 17 Andreyev AY, ... proteins residing in both the inner and outer mitochondrial membrane, that is activated by mitochondrial Ca2+ overloading and other factors including oxidative stress [88,89] In neurons the presence...

Ngày tải lên: 07/03/2014, 12:20

... hormone signaling, biotic and abiotic stress responses, and development [15,16], whereas high concentrations of ROS can result in oxidative stress and cause irreversible damage and hypersensitive response-like ... signaling pathways Results Expression of GhMPK2 was upregulated by oxidative stress and phytohormones To study the effect of oxidative stress and signaling molecules on the expression of GhMPK2, total ... transgenic plants to oxidative stress To observe the growth performance of tobacco plants under oxidative stress conditions, the wild-type and transgenic seeds were surface-sterilized and germinated...

Ngày tải lên: 14/03/2014, 23:20

... ROS production assay and real-time RT-PCR experiments, and participated in the study design and in drafting the manuscript JG isolated and set up the chondrocyte cultures and performed some experiments ... endothelial and smooth muscle cells under high-glucose conditions Circ Res 2005, 97:1001-1008 Cohen G, Riahi Y, Alpert E, Gruzman A, Sasson S: The roles of hyperglycaemia and oxidative stress in ... Results Basal and IL-1β-induced glucose transport and GLUT-1 content in normal and osteoarthritis chondrocytes Figure 1a reveals that the basal 2-DG uptake was identical in normal and OA chondrocytes...

Ngày tải lên: 09/08/2014, 14:21

... oxidative stress altered transactivation by EBNA1 and Tat in a manner opposite to the effect of hypoxia Differing effects of the oxidizing agents menadione and paraquot on Tat and EBNA1 EBV and ... Hypoxia alters transactivation by Tat and EBNA1 EBNA1 and Tat contain redox-sensitive cysteines that are essential for transactivation [18,28], and oxidative stress is known to alter the ability ... generation and thereby circumvent the difficulty in inducing oxidative stress by solely increasing pO2 [49] Menadione and paraquot are most frequently used to increase intracellular hydroxyl and superoxide...

Ngày tải lên: 12/08/2014, 04:20

... The Netherlands) Q-PCR of oxidative- stress proteins, copper metabolism and other related signaling molecules Q-PCR was performed on a total of 17 genes involved in oxidative stress and copper ... Doberman pinchers copper accumulates in time and, finally, will have its negative effect on copper metabolism and induce oxidative stress Oxidative stress has been ascribed to copper toxicosis ... toxicity is often associated with oxidative stress, we also measured several oxidative stress related gene-products To determine a possible damaging effect of the oxidative stress, we investigated proteins...

Ngày tải lên: 13/08/2014, 13:20