excitotoxic and other lesions of the rat striatum

... density of each experimental point Therefore, according to the RSDM analysis [21], most of the 15N–1H vectors of the TTF-1 HD core move at the rate of the overall rotational correlation frequency, and ... Fig The localization of the experimental points in Fig along the correlation line is directly related to the distribution of the energy between the overall tumbling and the internal mobility, and ... cross-relaxation rate; that is, it is largely determined by the heteronuclear NOE and thus it is most sensitive to high-frequency motions of the protein backbone On the other hand, the value of J(xN)...

Ngày tải lên: 18/02/2014, 16:20

... i.e., the smallest observation, the lower quartile and the upper quartile cutting off the lowest and highest 25% of the data, respectively, the median which is the middle value of the data and the ... denotes the conversion of the Au(III), X the value of any of the five parameters of each broth, Cov(X, Y) the covariance value and rxy the correlation coefficient of X and Y with a range of [-1, ... A0, A1 and A2 are absorbance of the blank, the sample and the control, respectively The SR50 value, which denotes the concentration of the leaves required to remove 50% DPPH radicals in the solution,...

Ngày tải lên: 21/06/2014, 17:20

... been evolved for the MMPs in potentially malignant and malignant lesions of the head and neck Further research is required for the development of their potential diagnostic and therapeutic possibilities ... aims to review the role, polymorphic association, gene expression of ECM and possible therapeutic aspects of MMPs and TIMPs in potentially malignant and malignant lesions of the head and neck Classification ... Classification of MMP gene family and their substrates Currently, 24 different types of MMPs have been identified among vertebrates, 23 of them have been found in humans [21-23] The members of the MMP...

Ngày tải lên: 10/08/2014, 05:21

... most haemorrhages of the white line and cows that had calved 4-6 months ago had most haemorrhages of the sole Other risk factors The age of the stall was correlated with several of the factors that ... studies, and the risk factors detected in the study can only be indicative of associations to help generate hypotheses The low number of recorded cases of dermatitis and sole ulcers made the detection ... whereas the prevalence of lameness, remarks to the carpus and the tarsus and different claw lesions is given in Table Twenty nine percent of the heifers had one or more remarks to the hind claws The...

Ngày tải lên: 12/08/2014, 15:21

... each band on the basis of its size, to normalize the intensity of the staining for the different sizes of the fragments The final percentage content of each MHC gene in the total sample was then ... relaxation time is the time from the peak to one-half of the maximum generated force; fatigue is the ratio of force generated at s after the initiation of protocol to the initial force generated *P ≤ ... beyond the influence of a pure increase in the workload on the muscle In addition to being the first demonstration of a decrease in the expression of the IIb MHC isoform in an animal model of emphysema,...

Ngày tải lên: 12/08/2014, 18:20

... SLEEP AND THE AWAKENING VII THE COUNTRY OF CRATERS, THE PATH OF SKULLS, AND THE SNAKE VIII - THE CATACLYSM THE PRIESTESS "LOOK AND FORGET" IX FORTY YEARS! THE AWAKENING THE SALTING OF THE GREAT ... respite, for the bushes were few, and I could find no sign of others or of t'samma And so for days I wandered, finding a few of the berries here and there, often half maddened and stupefied by them, ... front of us, and another and another and a tiger- wolf (hyena) lurched its gorged and ungainly carcass down the farther slope The fire was alive, but those that had built and lit it were dead of...

Ngày tải lên: 06/03/2014, 03:21

... sheets and 8, the AAA domain helix and the C-terminal helix) However, the majority of these proteins are likely to be other meiotic clade AAA ATPases and have the AAA domain helix and the C-terminal ... not the b domain The distinguishing feature of members of the meiotic clade of AAA ATPases is the SRH motif, which differs from that of other AAA ATPases [24] The pair of Arg residues in the ... important One of these, the TRP sequence, includes the start of the C-terminal helix as well as the structured loop between the 1440 ATPase domain and the C-terminal helix and in the 3D structure...

Ngày tải lên: 07/03/2014, 05:20

... amino acids and cysteines Tagging of Ntcp mutants by the FLAGÒ motif To determine whether the wild-type and the mutant proteins are expressed and located on the surface of the oocytes, the cDNA ... domains model), is involved in taurocholate transport of the human isoform [21] We therefore looked for the role of each of the eight cysteines of the rat Ntcp for taurocholate transport Finally, threonines, ... humans and rats begins by uptake across the basolateral membrane of hepatocytes via the high affinity, Fig Detection of the presence of Ntcp proteins in the cell membrane of X laevis oocytes by the...

Ngày tải lên: 17/03/2014, 09:20

... further uptake and preserving or enhancing their excretion The discovery of bile acids as ligands of the orphan liver receptor FXR [14] led to the concept of FXR-mediated regulation of Ntcp and Bsep ... and b-estradiol; 50 lmolÆL)1 each of phenobarbital, rifampin, and tamoxifen Assay conditions were the same as described in Fig *P < 0.05 the specific band Supershifted bands were rather weak and ... Paine, A.J (1993) Alteration of transcription factor mRNAs during the isolation and culture of rat hepatocytes suggests the activation of a proliferative mode underlies their dedifferentiation...

Ngày tải lên: 17/03/2014, 23:20

... the vernacular of many of those providing the information and of many of the ultimate users of the study results Figure A presents a simplified model of the fate and transport of science in environmental ... dozen There was an effort to ensure balance in the group of respondents for any particular case study, but because of the relatively small number of respondents and the non-random nature of the ... pedestrian As a group, the cases tend toward the “high-profile” end of the distribution of EPA decisions Nevertheless, among the case studies, there is some variability in the political and economic stakes...

Ngày tải lên: 24/03/2014, 05:20

... nutrient content may then be further increased during the storage, transportation and preparation of the foodstuffs prior to reaching the plate of the consumer An understanding of the various factors ... methods of the crop or livestock product analysed (including the name of any certifying body) - specification of the cultivar of crop, or breed of livestock - a statement of which nutrient(s) and other ... alerted to the review process and the availability of the review protocol A draft of the final report was reviewed and approved by the independent review panel 4.2 Search strategy Search strategies...

Ngày tải lên: 28/03/2014, 19:20

... part of the “Land of Israel” and that it is their religious duty to settle in the West Bank They are the pioneers of the settlement movement and typically live in settlements in the northern and ... on the claim that they serve the “natural growth” needs of a settlement.24 The creation of an outpost close to a settlement expands the amount of land under the mother settlement's control The ... Area C under the Oslo Accords) and the majority are located along the eastern strip of the West Bank.31 The declaration of land as a nature reserve severely restricts all other use and all development...

Ngày tải lên: 29/03/2014, 08:20

... report the effects of these mutations on the thermodynamic properties of the FAD and also their consequences on the kinetics of FAD reduction The thermodynamic properties of the wild-type and mutant ... bleaching of the absorption in the region of the two major absorption bands of the flavin, while there is development, and then decay, of absorption at longer wavelength due to the formation of the ... cofactors, and also of the haems in the case of NOS and P450 BM3 In spectroelectrochemical titrations of the isolated domains, the lack of overlapping spectral contributions from other cofactors...

Ngày tải lên: 30/03/2014, 14:20

... lasted the entire duration of the study [9,10] In view of the pivotal nature of these studies, it is important to understand the nature of these improvements and factors that may influence them ... over time as the left-hand panel (error bars are standard error) The right-hand plots are from a repeated measures analysis of the effects of treatment over the years of the study and are pair-wise ... per year, the SGRQ deteriorated: 2.8 (95% CI 2.1 to 3.6) units/year Early withdrawal and SGRQ There was a clear effect of both baseline SGRQ and rate of deterioration during the study on the likelihood...

Ngày tải lên: 12/08/2014, 13:22

... and design of the study, performed the animal experiments and revised the manuscript carefully RRW contributed to the conception of the study and the data interpretation, and revised the manuscript ... interpretation of the data LK performed the histological analysis, calculated the data and made substantial contribution to the analysis and interpretation of the data WB contributed to the conception and ... performed the animal experiments and wrote the first draft of the manuscript SW performed the histological analysis, calculated the data and made substantial contribution to the analysis and interpretation...

Ngày tải lên: 12/08/2014, 15:20

... F99K, F99N, F99Q, F99H, F99A), none of them reversed the inhibitory effect of H69E on protease maturation (not all the mutants are shown here) and many of them further suppressed autoprocess activity ... point Page of mutations between NL4-3 and wtpse protease, our data suggested that the inhibitory effect of H69E on protease autoprocessing is influenced by other residues C95 and other residues ... following the removal of inhibitors [37] Reducing agent DTT enhances protease maturation, and oxidizing agents delay protease maturation of the immature virions These results suggest an oxidation -and- reduction...

Ngày tải lên: 12/08/2014, 23:23

... among the lobes of the liver were observed in AG28262 treated rats The largest increase in ALT mRNA was in the caudate lobe, followed by the right medial, and lastly the left lateral lobe The caudate ... inhibitor, in treated rats in the absence of morphological changes in the liver The results of this investigation suggests that the source of increased serum ALT in AG28262 treated rats is due to an ... recorded The left lateral, right medial and caudate lobes of the liver were collected, weighed, and examined for gross lesions Liver lobes were selected based upon the differential distribution of the...

Ngày tải lên: 13/08/2014, 13:20

... incorporate information other than the past history of earnings into their forecasts of future earnings If there were an increase in the importance o f other information to firm valuation then the ... at the theoretical values o f the coefficients The coefficients depend on the persistence o f abnormal eamings and the persistence o f other information I hypothesize that the persistence of ... model and hypotheses Section describes the research design and reports the results o f empirical tests of the roles of eamings and other information in firm valuation Section describes the research...

Ngày tải lên: 30/09/2015, 16:44

... mentioned The men, especially the husband and the grandfather, sip alcohol and tell their family members what they see and hear or remind them of right or wrong things in life The others also ... difficult The oldest or the husband of the family sits at the head of the table and others sit in descending order according to age or wherever they like The meal starts when everyone has their own ... denoting the objects covered by the scope of the notion expressed in the word, and the significative function is the function of expressing the content of the respective notion The function of rendering...

Ngày tải lên: 15/04/2013, 15:11

... “Introduction” states the rationale of the study, Semantics can be simply defined as the study of meaning It defines the aims, objectives and the significance, presents the is central to the study of communication ... Another name for strategies might condition of the atmosphere E.g, warm weather, cold weather, wet be attitudes Many proverbs rely on antithesis: "Out of sight, out weather, dry weather, etc of ... comprehensive literature review of the research Chapter 3: “Methodology and Procedures” mentions the method and procedures of the research Chapter 4: “Findings and Discussions” is the main frame of need...

Ngày tải lên: 26/11/2013, 13:21