excitation—the process of eliciting the action potential
Báo cáo y học: "Repolarization of the action potential enabled by Na+ channel deactivation in PSpice simulation of cardiac muscle propagation" ppt
Ngày tải lên :
13/08/2014, 23:20
... showing how variations in the delay time (RC time constant), controlling the activation of the second black box (BB-2), affected the duration of the action potentials (APD50) The records were obtained ... circuit for regulating the shape of the cardiac AP (e.g to produce the typical spike and plateau of the cardiac action potential) Appendix The circuit shown in Figure depicts the novel circuit design ... closer comparison to the physiological waveform for the cardiac action potential In this circuit, BB-1 mimics the function of the fast Na+ channel and BB-2 mimics the function of the slow Na+ channel...
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báo cáo hóa học: " Behaviour of motor unit action potential rate, estimated from surface EMG, as a measure of muscle activation level" potx
Ngày tải lên :
19/06/2014, 10:20
... contribute to the signal MUs may partly lie within the detection area and it depends on the location of the center of the MU whether it is included in the estimate of the number of MUs or not Furthermore, ... algorithms, the first step of decomposition is the detection of MUAPs in the signal The second step consists of the assignment of the detected MUAPs to the MU that generated them (classification) Other ... good estimate of the number of MUAPs in the simulated signals, all MUs had to be located within the detection area of the electrode; else, the number of MUs that contributed to the signal could...
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Báo cáo y học: "Boundary effects influence velocity of transverse propagation of simulated cardiac action potentials" potx
Ngày tải lên :
13/08/2014, 23:20
... simulated cardiac action potentials as a function of the ratio of relative edge Plot of transverse velocityTable 2) Plot of transverse velocity of propagation of the simulated cardiac action potentials ... function of the ratio of relative edge area to interior area (see Table 2) of the time sequence of firing of the various chains The stimulated chain always begins to respond first, but there is ... with the exception of failure of one chain (the most distal A-chain) in the retrograde direction (Table 1) Therefore, in the largest model, there is an increase in probability of failure of one...
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UK MARKET POTENTIAL FOR SLOVENIAN WINE - CASE STUDY OF THE INTERNATIONALISATION PROCESS OF THE SLOVENIAN WINE PRODUCER pdf
Ngày tải lên :
08/03/2014, 04:22
... dependant upon the following factors: the size of the firm, the age of the firm, the technology level of the firm, the age of the CEO, occurrence of planning and the perceived dynamism in the firm’s ... relationships in the UK, the mode of entry, determination and commitment of the people to the goal etc will determine whether they can convince the UK consumer that the product is the right one The most ... stability of profits” However, despite the underlying profit making motive, there can be further discussion of the proactive and reactive motives, since this might influence the success of the company’s...
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Investigations into the chemopreventive potential of stilbenes, indolinones and isoindigos synthesis and mode of action studies
Ngày tải lên :
11/09/2015, 09:06
... circumventing the metabolic susceptibility of the OH group Of the various bioisosteres available, the indolin-2-one was chosen for the present work because of the synthetic accessibility of this moiety ... with a strong base The 18 reaction of the ylid with the carbonyl group of the benzaldehyde yielded the stilbene, as shown in Scheme 2-1 Scheme 2-1: The mechanism of Wittig reaction X Ph3P X HC ... product The synthesis of the 3-substituted indolin-2-ones (1-48) was carried out in the presence of the base piperidine as catalyst Under these conditions, the enol tautomer of oxindole forms the...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
Ngày tải lên :
26/10/2012, 10:04
... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... hydrolysis-resistant, synthetic S-analogs of natural O-glucosides involved in the biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism ... larvae of beetles (Chrysomelidae) Their synthesis has been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences...
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Another Piece of the Action
Ngày tải lên :
06/11/2012, 16:13
... that exact same moment of time There was the smell of the perfume she had chosen that day, the quality of her voice, the people that were in the corridor at the same time, and the way she had looked ... to the background sounds, like doors opening or closing, the hum of life support, and the quality of the air, there was also the internal dialogue he had been thinking, his emotional state, the ... time one of them would reproduce the works of Shakespeare Shakespeare was one thing, but two groups of monkeys knocking out a Preamble to the Constitution? Even on Earth the Constitution of the United...
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The Inbuilt Potentiality of Creation
Ngày tải lên :
01/11/2013, 08:20
... understanding of the fertile potentiality of the laws of nature will require a recognition of the role of their holistic, informational aspects? Once again, one encounters the inescapable degree of ambiguity ... Chapter 1) Together, these constitute a cumulative case for theism in which the God hypothesis does a number of pieces of explanatory work On the other hand, the conjecture that there are many, ... 10, 2004 The Inbuilt Potentiality of Creation 2:25 253 issue, the scales begin to tilt There are many other reasons for belief in God – the deep intelligibility of the world (a kind of cosmological...
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Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf
Ngày tải lên :
19/02/2014, 12:20
... analyzed by MALDI-TOF MS The addition of the protease is considered the zero time point The relative intensities of the peaks from the mass spectra were used to calculate the fraction of Pyr-ONC (M23L), ... (M23L) (theoretical molecular mass 11 801.60), and expressing it as the fraction of hydrolyzed (Met1)-ONC (M23L) Figure shows the results of the characterization of the hydrolysis reaction as ... (M23L) by the addition of AAP, as described in the Materials and methods Completion of the hydrolysis was confirmed by the disappearance of the (Met1)-ONC (M23L) signal in the MALDI-TOF mass spectra...
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Tài liệu Báo cáo khoa học: Involvement of two positively charged residues of Chlamydomonas reinhardtii glyceraldehyde-3-phosphate dehydrogenase in the assembly process of a bi-enzyme complex involved in CO2 assimilation doc
Ngày tải lên :
19/02/2014, 16:20
... molecular modelling of all mutant GAPDHs indicate no changes of the global structure of the mutants To test whether the interactions of these mutants with the other partners of the GAPDHCP12PRK ... the solvent and could thus be potentially involved in the interaction with the other partners of the GAPDHCP12PRK complex The model of wild-type GAPDH from C reinhardtii, like the structure of ... Comparison of the kinetics of these mutants with those of the wild-type recombinant GAPDH shows that the behaviour of R197A mutant is not affected by the mutation, suggesting that the active site and the...
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
Ngày tải lên :
20/02/2014, 11:20
... that the cytotoxic activity of the latter monomers was due to the presence in these proteins of disulde bonds, with their potential chemical instability It is well known that in the presence of ... reaction with methyl aminoethanethiosulfonate of the sulfhydryls exposed by selective reduction of the Table Monomeric derivatives of BS-RNase LC50 is the protein concentration producing 50% of ... the inhibitory action of CRI We tested the cytotoxic activity of the monomeric derivatives described above on malignant SVT2-3T3 broblasts by measuring cell survival after 48 h of growth in the...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
Ngày tải lên :
20/02/2014, 11:20
... which synthesizes components of the cuticle, may offer a useful target for studies into the mechanism of the development and molting process in the roundworms Investigation into the effects of fluoride ... staining), and that the inhibition of PPasecatalyzed PPi hydrolysis by these inhibitors, is likely to prevent the synthesis of the new cuticle from the hypodermis and/or ecdysis of the old cuticle ... ecdysis of an old cuticle and deposition of the components of a new cuticle that are synthesized in the hypodermis and are secreted across the hypodermal membrane into the space between it and the...
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Tài liệu Báo cáo khoa học: "The Structure and Process of Talking About Doing" pdf
Ngày tải lên :
21/02/2014, 20:20
... our model of the role of point of view in problem solving SUMMARY We have reported here a three pronged approach to the study of problem solving action and report: I) the collected of data on ... solving, 2) development of a process model of these behaviors, and 3) use of coding techniques to extract traces of "critical phenomena" from the transcripts for evaluating the model So far, we ... types of problem solving phenomena: the changes in the problem solver's organization of the problem ("point of view"), and systematic multl-utterance structures used to express the forms of inference...
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NATIONAL REPORT OF MALAYSIA ON THE FORMULATION OF A TRANSBOUNDARY DIAGNOSTIC ANALYSIS AND PRELIMINARY FRAMEWORK OF A STRATEGIC ACTION PROGRAMME FOR THE BAY OF BENGAL potx
Ngày tải lên :
06/03/2014, 15:21
... TAI The Straits of Singapore The Straits of Singapore The Straits of Malacca The Straits of Singapore The Straits of Singapore The Straits of Malacca The South China Sea The South China Sea The ... information on the use of, and threats to, the Malaysian coastal and marine resources off the Straits of Malacca and the adjacent waters of the Andaman Sea and the Indian Ocean In the process, an attempt ... is in the Andaman Sea at the northern tip of the Straits, while the shallowest is at the One Fathom Bank in the south The current predominantly flows in a northwest direction with rates of to...
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No DREAMers Left Behind - The Economic Potential of DREAM Act Beneficiaries potx
Ngày tải lên :
08/03/2014, 06:20
... potential barriers to achieving legalization By examining the historical trends of these barriers’ effects on the educational attainment of immigrant groups, the report estimates the number of ... the U.S at a young age, and in many cases the U.S is the only country they know and the one with which they most identify They have a strong desire to contribute to it more fully Passage of the ... family incomes below 200 percent of the federal poverty level, and 35 percent have limited English proficiency The majority of them are currently in the workforce These characteristics present challenges...
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Báo cáo Y học: Characterization of a low redox potential laccase from the basidiomycete C30 pptx
Ngày tải lên :
08/03/2014, 09:20
... On the other hand, when tested at their respective optimum pH values, the two isoforms are the most active at the same temperature of 55 °C The amino acid sequences deduced from lac1, the gene ... the differences in kinetics observed may be the consequence of the variability of certain of the amino acids involved in the substrates channel in specific enzymes A substantial variation in the ... the folding of the T1 copper pocket of the two enzymes, such as that mentioned above to explain their difference in T1 potential, could also account for their specific interaction with the substrates...
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Báo cáo khoa học: "A NEW VIEW ON THE PROCESS OF TRANSLATION" pdf
Ngày tải lên :
09/03/2014, 01:20
... translation Because the prepositional phrase is a modifier of the main process (indicated by the role feature and the fact that the main process and the modifier are siblings in the IS representation) ... the projects involved, and the structure of the German-Engllsh transfer mechanism, offering specific examples of the transfer process for some of the features present in the IS analysis It is also ... roleconfigurations are mapped The UMG concepts then The Nature of the Transla- tion Process It is important from a conceptual point of view to keep apart the three levels of representation involved...
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the importance and impacts of costing method on the process of managerial decision making
Ngày tải lên :
13/03/2014, 14:20
... increase the number of the ending inventories as well as the profit of the organizations as mentioned above This not only can be considered as a strategy of the new comers to attract the investments ... profits of the companies without pressure of selling products They need another way to differentiate their business with other Therefore, besides of applying only absorption costing method, they ... Sometimes, the ending inventories of these companies can be more than 50% of the total number of products that they produce each month This is because the percentage of depreciation in value of raincoats...
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the importance and impacts ofcosting method on the process of managerial decision making
Ngày tải lên :
13/03/2014, 14:20
... most of the analysis is based on the studies of other researchers so it can be debatable and difficult for users to apply in the reality 28 The major limitation of this study is the use of secondary ... making process of the managers This will be the answer to the question: “whether the cost accounting method can have any 41 significant impacts on the decisions of managers, and what is the importance ... INTRODUCTION In this chapter, the whole picture about the ideas of this thesis will be depicted, and these help users easy to follow and link them to each other to figure out the potential relationship...
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Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
Ngày tải lên :
16/03/2014, 00:20
... the basis of the Ping Pong mechanism, the acetylation rate (k2) of NAT2 by the acetyl donor is independent of the transacetylation rate (k4) of the arylamine substrate Because the values of k4 for ... Trp177 and the imidazole of the catalytic triad His159 in the papain-like Cys proteinase [44] Mutations of the Trp to either Tyr, Phe, Ile or Ala (the strength of the Hisaromatic interaction decreases ... truncations, the availability of the Tyr190 mutants makes it feasible to conduct cell-based studies of the effects of the stability of the acetylated enzyme intermediate on the N-acetylation of aromatic...
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