... for bias inthe results and is a limitation of the study Medical errors are among the leading causes of death inthe United States In its highly publicised report, the Institute of Medicine estimates ... those reported in a recent study of prescription errors in UK critical care units [12] There was no difference inthe mean APACHE II score inthe HWP and CPOE periods, indicating that it is unlikely ... using the Clinical Informacomputerised physician order entry (CPOE) using the Clinical Information System with 95% confidence intervals Hand-written prescribing (HWP) data collection began on the...
... intensivecare and general care units Crit Care Med 1997, 25:1289-1297 12 Herout PM, Erstad BL: Medication errors involving continuously infused medications in a surgical intensivecareunit Crit Care ... defined as calculated creatinine clearance less than 50 ml/minute The parameters needed to calculate the creatinine clearance were always available in both the PB-U and the C-U In addition to the ... these units, usually on a one-week basis One month after the completion of the study, the ICIS was implemented inthe two other remaining units Approval of the ethics committee was obtained; informed...
... D insufficient However, the prevalence of vitamin D insufficiency is even higher in subjects admitted to theintensivecareunit with critical illness We also demonstrate that vitamin D binding ... 25-hydroxyvitamin D lost inthe urine [24] This process is facilitated by megalin, a protein located on the renal epithelial cell which binds to the DBP-25-hydroxyvitamin D complex to facilitate the recovery ... healthy controls, as expected inthe setting of illness requiring intensivecare Both critically ill groups also had significantly lower serum albumin, indicating that the two groups had higher disease...
... characteristics of pathogens causing HAP intheIntensivecareunit of Bach Mai Hospital which is the area with the highest incidence density of healthcare associated infections among Vietnamese HCFs ... characteristics of pathogens causing HAP These findings suggest areas for intervention and for developing guideline for prevention and control of HAP in HCFs THESIS STRUCTURE The thesis consists of 129 ... be inhaled by susceptible individuals through the dissemination of either airborne droplet nuclei or small particles (< 5μm )in the respirable size range containing infectious agents that remain...
... tamponade following cardiothoracic surgery intheintensivecareunit Journal of Cardiothoracic Surgery 2011 6:79 Competing interests The authors declare that they have no competing interests Received: ... obtained during monitoring intheintensivecareunit (ICU) [5,6,8,9,11,13] When pericardial tamponade was suspected, 52% of our patients had a improvement of the CV SOFA score, with a rise in ... performed routinely Haemodynamic monitoring was routinely done with help of a catheter inthe radial artery and either a central venous catheter and/or a pulmonary artery catheter (n = 14) The latter...
... hepatitis C virus; ICU: intensivecare unit; IV: intravenous; NE: norepinephrine; RCT: randomized controlled trial Competing interests The authors declare that they have no competing interests Authors' ... continue for a long time without obvious adverse effects or major organ toxicity is, in our opinion, the most interesting finding in our report Therefore, we believe that this report is a meaningful ... care and edited the manuscript All authors read and approved the final manuscript Acknowledgements We want to thank the nursing and ancillary staff of theintensivecareunit at the Patras University...
... haemoglobin concentrations during the first 10 days of intensivecareunit (ICU) stay There was an average decrease of 16 g/l in haemoglobin concentrations in all patients admitted to the ICU over the ... Variation in red cell transfusion practice intheintensivecareunit Hébert et al For the bedside questionnaire, we determined the response rate at each institution by cross checking recorded ... if they initiated the request or if another physician requested the administration of red cells Physicians requesting the transfusion were then asked to identify the most important reason for the...
... existing monitors intheintensivecareunit Crit Care Med 1997, 25:614–619 Chambrin MC, Ravaux P, Calvelo D, Jaborska A, Chopin C, Boniface B: Multicentric study of monitoring alarms inthe adult ... of the patient from the ventilator produces the same audible alarm as a high level of minute ventilation Inthe first case, the alarm is vital for the patient and independent of any setting The ... sleep disruption in an intermediate respiratory careunit Sleep 1996, 19:707–710 Kam PCA, Kam AC, Thompson JF: Noise pollution inthe anaesthetic and intensivecare environment Anaesthesia 1994,...
... Care 10 11 12 13 14 15 16 17 18 19 20 21 22 August 2001 Vol No Kollef of nosocomial infection inintensivecare units in Europe: results of the European Prevalence of Infection inIntensiveCare ... reduction in its use, a sustained reduction inthe Kollef et al examined the influence of a scheduled change in antibiotic on the incidence of nosocomial infections among patients undergoing cardiac ... improve the efficacy of antimicrobial therapy by increasing the likelihood for adequate initial treatment of infections [6] Antimicrobial de-escalation There is increasing clinical evidence suggesting...
... succinylcholine administration, caused by stimulation of nicotinic receptors inthe autonomic ganglia (sympathetic and parasympathetic) and of cardiac muscarinic receptors [16] Furthermore, succinylcholine ... [16] Furthermore, succinylcholine increases plasma noradrenaline (norepinephrine) concentrations, resulting in cardiovascular effects Finally, the histamine-releasing properties of muscle relaxants ... cholinesterase, the interindividual variability in effect is as wide as with succinylcholine [18] Many studies have shown that rocuronium is a highly acceptable replacement for succinylcholine inthe ICU; therefore,...
... reducing resource utilization inthe surgical intensivecareunitIntensiveCare Med 2001, 27:1029-1036 Miller R, Goodman K: Ethical challenges inthe use of decisionsupport software in clinical ... Intermountain Respiratory IntensiveCareUnit and of the ShockTrauma/Intermountain Respiratory ICU, and to the Respiratory Care Department of the LDS Hospital, for collaboration during the past ... demeaning the clinical training of students and house officers, I Competing interests None declared Acknowledgements I am indebted to the medical, nursing, and respiratory therapy staffs of the Intermountain...
... implement changes in individual intensivecare units.” Indeed, physicians want to improve their delivery of care, but often lack an understanding of the basic theories that are necessary for their quality ... understanding of pathophysiology and pharmacokinetics, few clinicians or researchers possess formalized training in systems thinking, the process of quality improvement, concepts regarding changing ... at other sites Quality improvement intheintensivecareunit Perhaps one of the most provocative comments made by Chan et al [3] is found inthe abstract of their report: “… research evidence...
... resistances are questionable considering the remarkable stability of mecA inthe MRSA, vancomycinresistant determinants inthe enterococci, or integrons in nature, even inthe absence of antibiotic pressure ... and transposons, the more recently described integrons can capture multiple gene cassettes, express them, and then integrate them into the chromosome [7] The genes found in integrons often encode ... be obtained between hospital administration, health carers, and pharmacists: all prescribers have to follow the guidelines; the different regimens used inthe rotation must be chosen inthe light...
... Japan) The treating clinicians were blinded to the PCT results, and those performing the PCT assays were blinded to the clinical status of the patient The PCT results were not available during the ... aminotransferase, alanine aminotransferase, prothrombin time, activated partial thromboplastin time, albumin, transferrin and CRP); and arterial blood gas analysis The final determination of the ... diseases in an intensivecareunit (ICU) Method The study was approved by the Institutional Ethics Committees of the Pamukkale University Medical School Written informed consent was obtained from...
... Critical care: why there is no global bioethics J Med Philos 1998, 23:643-651 22 European Society of IntensiveCare Medicine: International Consensus Conference inIntensiveCare Medicine: Preliminary ... and sedation in dying intensivecareunit patients BMC Med Ethics 2002, 3:3 [http://www.biomedcentral.com/1472-6939/3/3] Campbell ML: Forgoing life-sustaining therapy: how to care for the patient ... strides have been made in defining ethical principles to guide end-of-life careinthe 35 years since a panel reached consensus on guidelines to define brain death [20] Nevertheless, it is important...
... Pitfalls of monitoring sedation inthe ICU with the bispectral index Anesthesiology 1998, 89:A461 Simmons LE, Riker RR, Prato BS, Fraser GL: Assessing sedation during intensivecareunit mechanical ... and bilirubin, alanine aminotransferase and creatinine (Vitalab Flexor, Dieren, The Netherlands) were determined at baseline (15 before start of the study), immediately after sedative infusion ... for sedation intheintensivecare unit? Crit Care Med 1999, 27:1663-1664 Frenzel D, Greim CA, Sommer C, Bauerle K, Roewer N: Is the bispectral index appropriate for monitoring the sedation level...
... without pain was treated either by reducing or by discontinuing the propofol (if being administered) or opioid infusion Pain was treated with an opioid bolus dose and an increase inthe opioid infusion ... were being made to enter the patient into the study The treatment period was defined as the following four phases: maintenance phase (from the start of the study drug until the start of the extubation ... cost savings [21,27] Remifentanil may permit improvement in patient comfort inthe ICU by optimizing the use of the opioid component by initiating and titrating the opioid infusion before administration...
... intheintensivecareunitThe circulating level of a given molecule depends on three factors: the rate of production and release of the molecule, the rate of its removal, and the volume within ... value for the diagnosis of infection Low flux membranes did not alter these figures after the start of The emergence of theintensivecareunit as a locus for providing supportive care for critically ... to be triggered by invasive infection, with the result that levels inthe circulation increase The magnitude of this increase is clearly large enough to offset the reduction in concentration that...
... together how to resolve them Inthe upcoming Critical Care theme issue on research ethics, we shall examine some of the common challenging ethical and legal issues that plague us within the ICU ... community to ensure the quality of research or the quality of the critiques/commentaries they publish? Can the publishers be held accountable or even liable for the impact of the articles they ... if the now capable patient says he/she would never have given consent to participate inthe first place? What does risk mean when the stakes are so high to begin with? The main source of funding...