evidence of airborne transmission of the severe acute respiratory syndrome virus

... Asia in 2003. The causa- tive agent of SARS is a coronavirus-related virus [1,2]. The genome sequence of the SARS virus is only mod- erately similar to that of other species of coronaviruses [3] ... phosphorylation. Effect of RS motif phosphorylation on oligomerization of the N protein To better understand the effect of RS motif phosphor- ylation on the biological function of the N protein, we Fig. 3. The translation ... Journal compilation ª 2008 FEBS 4157 Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation...

Ngày tải lên: 23/03/2014, 07:20

... tail of the spike protein of most coronaviruses, mediates the intracellular retention of the spike protein. This motif is missing from the spike protein of the severe acute respiratory syndrome- coronavirus ... could confer certain advantages during the replication of the severe acute respiratory syndrome- coronavirus. Background The recent severe acute respiratory syndrome (SARS) epi- demic, which affected ... will indicate that the severe acute respiratory syndrome- coronavirus modulates the surface expression of the spike protein via a different mechanism from other coronaviruses. The interaction between...

Ngày tải lên: 18/06/2014, 22:20

... tail of the spike protein of most coronaviruses, mediates the intracellular retention of the spike protein. This motif is missing from the spike protein of the severe acute respiratory syndrome- coronavirus ... could confer certain advantages during the replication of the severe acute respiratory syndrome- coronavirus. Background The recent severe acute respiratory syndrome (SARS) epi- demic, which affected ... will indicate that the severe acute respiratory syndrome- coronavirus modulates the surface expression of the spike protein via a different mechanism from other coronaviruses. The interaction between...

Ngày tải lên: 20/06/2014, 04:20

... determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong. Lancet, 2003. 361:1761-6. 68. Pan S.F., et al. Cardiac arrest in severe acute respiratory syndrome: analysis of ... Effectiveness of non-invasive positive pressure ventilation in the treatment of acute respiratory failure in severe acute respiratory syndrome. Chest (in press) 44. Liu X.Q., et al. Management of critical ... Pattern of Disease in Patients with Severe Acute Respiratory Syndrome. Am J Roentgenol, 2004. 182:493-498. 64. Lew T.W., et al. Acute respiratory syndrome in critically-ill patients with severe acute...

Ngày tải lên: 03/11/2012, 10:20

... binding with the small molecule involves a larger molecular interface in the case of the former helicase. Further- more, the absence of the S259 OH group in the mutated viral enzyme prevents the formation ... Similarly, the structures of heli- case S ⁄ L and L ⁄ F mutants were obtained, and the atomic coordinates of the lowest energy structures of the wild-type form of SARS-CoV helicase are available from the ... interfere in the interaction of the enzyme with its natural substrates. The presence of the leucyl side chain in the protein mutant appears to cause steric hindrance to bananin binding, leaving the traffic...

Ngày tải lên: 28/03/2014, 23:20

Ngày tải lên: 12/08/2014, 23:20

Ngày tải lên: 12/08/2014, 18:21

Ngày tải lên: 08/08/2014, 12:22

Ngày tải lên: 12/08/2014, 01:22

... presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, ... efforts in the next few years will focus on responding to the needs of the ten countries with the highest number of pregnant women with HIV. It is in these countries, where 75% of the need for ... 000 80% The bar indicates the uncertainty range around the estimate. Percentage of pregnant women living with HIV receiving antiretrovirals to reduce the risk of mother-to-child transmission of...

Ngày tải lên: 14/03/2014, 09:20

Ngày tải lên: 13/08/2014, 03:20

... sequencing of a total of 6946 bp, which include the ata genes most likely implicated in the biosynthesis of this moiety of A201A. Evidence for the functional identification of three of these genes ... it. Further sequencing of the ata cluster could provide an insight into the biosynthetic pathway of the other moieties of A201A and provide probes which may be useful to identify genes of the hygromycin ... identical to those of the similar genes of the pur cluster. In Actinomyc- etes, this approach has led to the functional characterization of genes implicated in the biosynthesis of a variety of antibiotics...

Ngày tải lên: 21/02/2014, 01:21

... quality model to estimate the dispersion function, the accuracy of the estimated emissions will depend on the ability of the model to reproduce the dispersion of the pollutants. Until now, ... in the emission factors of VOCs for LDVs and HDVs. The emission factors calculated in this study are generally higher compared to the results of the other studies around the world. Only the ... observed at this period of the day. From 2 pm to 6 pm, the wind direction is oblique to the street axis and the wind speed is higher than in the morning. At these hours of the day, tracer ...

Ngày tải lên: 05/03/2014, 16:20

... absolutely ignorant of the meaning of the words Soul, Spirit, Intelligence: how, then, can we logically reason from the presence of the one to the existence of the other? I reject, then, even when ... further delay, that the hopes of the friends of association were groundless. Thus, then, the gentlemen of the Academy disavow, in their session-chamber, their announcements from the tripod! There ... seeking for the meaning and content of the idea of God; and that the tradesmen of the university will impute to me the impiety of demonstrating the non-value of their philosophical products, when...

Ngày tải lên: 15/03/2014, 07:20

... the death of holder thereof and before the maturity of the certificate, or before the certificate having reached maturity has been discharged, the nominee shall on the death of the holder of ... may be, appoint the person to receive payment of the amount due on the account in the event of death of the depositor or depositors, as the case may be, during the minority of the nominee. ... (iii) the period from the date of opening the account to the date of death of the depositor or surviving depositor, as the case may be, is not less than two years. (iv) The age of the depositor...

Ngày tải lên: 15/03/2014, 10:20

... itoescanserveasmechanicalvectors of PRRSVandcan transport the virus atleast2.4kmfromaninfectedfarm. The site of retentiono f the virus in the flyis the GItractand the rate of viraldecayovertimeisinfluencedbyquantity ingestedandenvironmentaltemperature.Inordertopreventspread of PRRSVvia insects the followingstepsarer ... Once the evacuationperiodisover, the interiordoorcanbeopenedallowing personnel/pigstoenterinside the facility orleave the facilityvia the external door. Aview of the baffleinletin the chamber Note: The doubledoorsystem ... is recommendedtoenhancedetection of peracuteinfections. Samples collectedlatein the isolationperiodcanalsobetestedby ELISAfor the presence of PRRSVantibodies. o With the advent of the bloodswabtechnique,AIcenterscanproactively monitor...

Ngày tải lên: 22/03/2014, 12:20

... you, the hypotheses of time, space, motion, thought, and the laws of thought. Then you may verify the hypothesis of pauperism, the hypothesis of inequality of conditions, the hypothesis of universal ... association, the hypothesis of happiness, the hypotheses of monarchy and republicanism, the hypothesis of Providence! . . . . A complete criticism of God and humanity. I point to the programme of the ... WHAT, THEN, IS THE TRUTH IN RELATION TO US, AND WHAT IS THE CHARACTER OF CERTAINTY? As if the Academy had said to us: You shall verify the hypothesis of your existence, the hypothesis of the...

Ngày tải lên: 29/03/2014, 12:20

... by tetramer staining in three of the four patients, although the frequencies of tetramer-positive cells were rather low in 2 of them as they did not exceed 0.2% of CD8+ T cells which was much lower ... protein either in the interferon-gamma ELISPOT assay or in the proliferation assay in five of the seven patients (figures 1 and 2). None of the 4 patients who remained negative in the anti-HCV ELISA ... [26,31,32]. Nevertheless, for the manage- ment of acute hepatitis C patients our study supports the concept to investigate the kinetic of HCV-viremia for 2–3 weeks before an antivirial therapy is considered...

Ngày tải lên: 18/06/2014, 18:20

... governmental activities in the statement of activities are different because: Governmental funds report capital outlays as expenditures. However, in the statement of activities the cost of those assets ... compensation liability reported in the statement of activities do not require the use of current financial resources and therefore are not reported as expenditures in the governmental funds until ... Accrual and other adjustments 2,338,525 12,655,143 Excess (deficiency) of revenues over expenditures – GAAP basis $ (22,934,844) $ 12,186,380 The following reconciles the excess of revenues...

Ngày tải lên: 18/06/2014, 20:20

... by tetramer staining in three of the four patients, although the frequencies of tetramer-positive cells were rather low in 2 of them as they did not exceed 0.2% of CD8+ T cells which was much lower ... [26,31,32]. Nevertheless, for the manage- ment of acute hepatitis C patients our study supports the concept to investigate the kinetic of HCV-viremia for 2–3 weeks before an antivirial therapy is considered ... clearance in the absence of anti-HCV. HCV-RNA levels, ALT levels and T cell responses are shown. Coloured bars show the sum of SI values of the proliferation assay and the sum of specific interferon-gamma...

Ngày tải lên: 20/06/2014, 01:20