evaluation of diagnostic and prognostic significance of current and potential markers
Skewness preference and measurement of abnormal returns, a comparative evaluation of current vs proposed event study paradigm
... by Friend and Blum (1970), Black, Jensen, and Scholes (1972), Miller and Scholes (1972), Fama and Macbeth (1973), and Blum and Friend (1973) suggest that the slope of the CAPM is lower and the ... where ctj and pi are the intercept and the slope, respectively, of the straight line defined on the [ E(Rmt), £(/?„) ] plane, and Rit and Rmt are the rates o f return on the iIh security and the ... with permission of the copyright owner Further reproduction prohibited without permission Skewness Preference and Measurement of Abnormal Returns: A Comparative Evaluation of Current Vs Proposed...
- 121
- 142
- 0
Evaluation of Current RDF Database Solutions ppt
... 2.2 shows, rdfDB and YARS not support SPARQL, these databases will not be part of the further evaluation Based on the evaluation in [7] the achieved evaluation of ARC, Redland and Virtuoso are ... consists of a set of parser and writer for the handling of RDF data This is for instance used by the Storage And Inference Layer (Sail) API for initializing, querying, modifying and the shut down of ... the expressiveness of SPARQL queries and the performance of the frameworks / applications SPARQL consists of four different query forms: SELECT, ASK, CONSTRUCT and DESCRIBE This evaluation is restricted...
- 17
- 381
- 0
Báo cáo khoa học: "Equipment review: The success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation" potx
... induction of apoptosis (e.g tumor necrosis factor and Fas ligand) [24], interleukin-6 [25], and other biochemical indices of inflammation have been proposed as diagnostic markers of sepsis and SIRS ... comes from the work of Rivers and coworkers [6], but there are also a number of optimization studies using forms of goal-directed therapy and SvO2 from groups such as that of Polonen [7] that ... least certain categories of patients (e.g those with a history of recent myocardial infarction) In the largest RCT to evaluate the use of the PAC, Sandham and coworkers [48] randomly assigned 1994...
- 11
- 381
- 0
Báo cáo y học: "Meeting the challenges of drug discovery: a multidisciplinary re-evaluation of current practices" pptx
... human patients with the aim of establishing tissue- and serum-based markers for both diagnostics and functional classification of disease He described the capture of cell-surface proteins via ... gene-expression profiling, in vitro assays and literature sources The power of the method was illustrated by the identification and use of kidney biomarkers as early predictors of nephrotoxicity ... properties, and more predictable toxicity profiles, which often mean a faster path to successful proofof-concept clinical trials Burley and Park 330.3 comment summarized the relative predictability of...
- 3
- 244
- 0
Screening and evaluation of the anticancer potential of scorpion venoms and snake venom l amino acid oxidase in gastric cancer
... SCREENING AND EVALUATION OF THE ANTICANCER POTENTIAL OF SCORPION VENOMS AND SNAKE VENOM L-AMINO ACID OXIDASE IN GASTRIC CANCER DING JIAN (B.S.c) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... discovery for animal venoms and toxins An increasing number of studies have shown the anticancer effects of venoms and toxins of snakes, scorpions and others in vitro and in vivo, which were achieved ... inhibition of cancer growth, arrest of cell cycle, induction of apoptosis and suppression of cancer metastasis However, more evidence is needed to support this concept and the mechanisms of anticancer...
- 226
- 584
- 0
EVALUATION OF CHALCONES FOR POTENTIAL ANTI INVASIVE PROPERTIES AGAINST BREAST CANCEL CELLS
... Effects of chalcones, ISL and PMA on viability of MDA-MB-231 cells 40 Figure 2.3 Effects of chalcones, ISL and PMA on viability of MCF-7 cells 44 Figure 2.4 Effects of chalcones and ... started with the evaluation of the cytotoxicity profiles of the chalcone analogs in MDA-MB-231 and MCF-7 breast carcinoma cells, followed by selection of relatively non-cytotoxic doses (5 and 10 μM) ... effects of chalcones and ISL on uPA secretion and expression level in PMA-induced MDA-MB-231 cells 65 Figure 3.6 Effects of CC7 and CC9 on transcriptional expression of MMP-9, MMP-7, MMP-13 and...
- 127
- 185
- 0
báo cáo khoa học: " Storage protein profiles in Spanish and runner market type peanuts and potential markers" pps
... standards The arrow ( protein band ) indicates the protein band with a molecular weight of 35 kDa and the arrow ( Ara h4, and iso-Ara h3 [13] (Fig 4) Interestingly, all amino acid sequences of ... subunits consist of the acidic polypeptides and the basic polypeptides [17] The uniformity of the one-dimensional SDS-PAGE protein profiles within the runner type and Spanish type cultivars and breeding ... Service and Peanut Foundation, and by funds provided by Scientific Cooperation Research Program of U S Department of Agriculture-Foreign Agricultural Service between U.S and China Mention of trade...
- 9
- 291
- 0
báo cáo hóa học:" Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma" docx
... p21/WAF1, and MDM2 in 181 pairs of HCC on the basis of different clinical parameters, including the gender, age, tumor size, number of tumors, HBsAg, pathologic grade, and serum level of AFP of the ... Figure Expression of p53, p21/WAF1 and MDM2 in HCC by IHC Expression of p53, p21/WAF1 and MDM2 in HCC by IHC The hematoxylin and eosin (H&E) stained sections show a solid area of hepatocellular ... http://www.translational-medicine.com/content/7/1/110 relation between p53 expression and the survival time of the patients (P = 0.275) Further analysis of the prognostic value of combining p21 and MDM2 expression in HCC was undertaken...
- 8
- 611
- 0
Báo cáo hóa học: " Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma''''" doc
... Oct4/ Sox2, clinicopathological characteristics and prognosis of hypopharyngeal squamous cell carcinoma Page of Table The expressions of Oct4 and Sox2 and their relationships with clinicopathological ... between the onset of treatment and the date when recurrence or metastasis was diagnosed OS, LRC and DFS probabilities were estimated by the KaplanMeier method and the significance of differences ... this article as: Ge et al.: Prognostic significance of Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma Journal of Translational Medicine 2010 8:94 Page of Submit your next manuscript...
- 7
- 493
- 0
Báo cáo hóa học: " Evaluation of the diagnostic indices and clinical utility of qualitative cardiodetect® test kit in diagnosis of ami within 12 hours of onset of chest pain in the emergency department" pptx
... as: Hisamuddin NAR and Suhailan M: Evaluation of the diagnostic indices and clinical utility of qualitative cardiodetect®® test kit in diagnosis of ami within 12 hours of onset of chest pain in ... sensitivity of serial measurements of multiple markers nears 100%, whereas the sensitivity of a single measurement of any biomarker at the time of Hisamuddin NAR and Suhailan M International Journal of ... criteria for the definition of AMI includes a combination of two out of three characteristics composed of clinical history, a rise and fall of cardiac biomarkers, and ECG changes Despite being...
- 9
- 463
- 0
Báo cáo khoa học: "Diffuse anorectal melanoma; review of the current diagnostic and treatment aspects based on a case report" doc
... (GIST), paragangglioma and neoplasm of melanocytic origin The positive expression of the HMB-45 and S-100 protein antibodies set the diagnosis of the malignant neoplasm of melanocytic origin (malignant ... concerning size, fixation and ulceration of the tumor and proctosigmoidoscopy may be suggestive of anorectal melanoma Figure Microscopic view of the permanent section Microscopic view of the permanent ... Figure The excised specimen of our case The excised specimen of our case disease and which should be the best surgical treatment for it? Finally, in what way the prognostic and clinicopathological...
- 4
- 311
- 0
Báo cáo khoa học: "Evaluation of clinical, laboratory and morphologic prognostic factors in colon cancer" ppsx
... symptoms and major medical problems of patients; laboratory data and neoplastic markers values; location, size, endoscopic appearance and preoperative staging of the tumour; operation type, degree of ... also that radical resection and type of operation are important prognostic factors In a recent Table 2: Results of multivariate analysis of clinical and laboratory data of patients with colon cancer ... predicting survival and recurrence and provide the grounds for further work in order to assess the prognostic significance of various clinical, laboratory, patho-morphological markers and to define...
- 7
- 452
- 0
Báo cáo khoa học: "Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients" doc
... http://www.ro-journal.com/content/6/1/100 Page of 10 Figure Prognostic value of TATI concentrations in tumour tissue and serum ROC curves showing estimations of the prognostic value of t-TATI in surgically obtained tissue (A) and s-TATI ... the latter, and an impaired survival is in line with previous results, and further supports the potential utility of TATI as a prognostic biomarker in patients with cancer of the colon and rectum, ... role of s-TATI as a prognostic biomarker in CRC For s-TATI, the optimal cut-offs derived from CRT analyses were identical to optimal cut-offs according to ROC curve analyses and s-TATI remained prognostic...
- 10
- 404
- 0
Báo cáo khoa học: "Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back" pot
... the prognostic value of MGMT-promoter methylation and IDH1 mutational status, we analyzed both markers in a homogenous group of 160 patients with primary GBM treated with radiation and TMZ and ... clinical analysis of the dataset CH and AvD performed the histopathological and molecular analysis SC, JD, CH and AA analyszed the prognostic relevance of the molecular data SC and CH wrote the ... infiltrating gliomas of the WHO grades II and III and in secondary GBM but only in around % of primary GBM (11;18-22) In our series we identified in of 140 patients (3 %) IDH-1 mutations Currently, it...
- 18
- 365
- 0
Báo cáo y học: "Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis" doc
... study of diagnostic value were included in a prospective study of prognostic factors in early RA Two years of follow-up data were available for 98 of 134 patients Results for radiographic and clinical ... CFFCP3) and to compare their sensitivity and specificity in RA and other disease groups with the commercial CCP2 test The prognostic value of these chimeric ACPAs also was studied in a cohort of patients ... population and reacted with some CCP2-negative sera [20] The aim of the present study was to evaluate the diagnostic yield of three ELISA tests based on this CFFCP1 peptide and Page of (page number...
- 9
- 317
- 0
báo cáo khoa học: "Expression and prognostic significance of cancer-testis antigens (CTA) in intrahepatic cholagiocarcinoma" ppt
... extent of immunostaining in sections and further graded into four groups: + : < 5% of tumor cells stained; ++ : 5-25% of tumor cells stained; +++ : > 25-50% of tumor cells stained; ++++ : > 50% of ... committee of our institutions, and informed consent was obtained from each patient A total of consecutive 102 patients with IHCC who underwent curative resection at Department of Hepatobiliary and ... al Journal of Experimental & Clinical Cancer Research 2011, 30:2 http://www.jeccr.com/content/30/1/2 The aims of the current study were to analyze the expression of MAGE-A1, MAGE-A3/4 and NY-ESO-1...
- 6
- 414
- 0
báo cáo khoa học: "Prognostic significance of STAT3 and phosphorylated STAT3 in human soft tissue tumors - a clinicopathological analysis" ppt
... malignant potential of soft tissue tumors and can be piloted as diagnostic marker in soft tissue tumors In the current study we observed a distinct pattern of STAT3 and pSTAT3 expression in soft tissue ... between STAT3 Page of Figure Expression of immunohistochemical markers, STAT3 (A, C, E) and p-STAT3 (B, D, F), in benign (A and B); intermediate (C and D); malignant (E and F) soft tissue tumors ... characteristics and expression of STAT3 in malignant soft tissue tumors Clinicopathological significance of STAT3 expression in soft tissue tumors In our study, the expression of STAT3 in soft tissue...
- 9
- 433
- 0
báo cáo khoa học: "Topoisomerase II alpha gene copy loss has adverse prognostic significance in ERBB2-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts" ppsx
... agents With the recent approval of Trastuzumab for the adjuvant treatment of BC and expanding its use, the importance of exploring molecular markers in the vicinity of ERBB2 is increased [43,44] ... manuscript BT and RR gathered and interpreted clinical data LM and KJ performed the FISH analysis and interpreted the data AZ and SB performed statistical analysis and helped to format and interpret ... M, Durand M, Avril A, Coindre JM, Parwaresch R: Prognostic significance of Ki-67 and topoisomerase IIα expression in infiltrating ductal carcinoma of the breast a multivariate analysis of 863...
- 10
- 375
- 0
Báo cáo khoa học: "Evaluation of Clinical and Laboratory Variables as Prognostic Indicators in Hospitalised Gastrointestinal Colic Horse" pdf
... euthanised and excluded from the study Of the final 92 horses 30 horses were warmblooded riding horses, 15 Norwegian coldblooded trotters, 15 Standard-bred trotters, 16 Thoroughbreds and 16 horses of ... were: (i) Recurrent pain despite heavy analgesic treatment and/ or (ii) Rec- 111 tal findings of distended small intestines and/ or (iii) Rectal findings corresponding to displacement of the large ... hospital according to a standard protocol Further, clinical and laboratory variables obtained during the stay in hospital were used as the basis of further treatment of the patient and not used in the...
- 10
- 237
- 0
Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... observation of cyclic edema demonstrated the success of the treatment and the need for its control, but we had no idea of the high prevalence of edema in the more advanced grades of cellulite The lack of ... complaints of any type of venous disease and had associated diagnoses of cellulite were included in the study Patients with body mass indexes > 25, Grade I cellulite and other causes of edema were ... were excluded An evaluation for idiopathic cyclic edema is routinely made in the diagnosis of cellulite, in obesity and in other evident causes of clinical edema The diagnosis of idiopathic cyclic...
- 3
- 462
- 1
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25