evaluation and treatment of visual field loss and visual spatial neglect
![Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc](https://media.store123doc.com/images/document/14/rc/rp/small_luUKRIz7Xm.jpg)
Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc
... Maurice and Erwan Magueur is greatly appreciated This work was supported by grants from the Lorraine Region and Urban Community of Grand Nancy (CUGN) and from the French Ministry of Research and ... and Higher Education PI is a recipient of a Research Fellowship from the French Ministry of Research and Higher Education, and FTY and BEB are Directors of Research at the ´ ´ Institut National ... B[a]P and adipocytes resulting in delayed recovery after withdrawal of B[a]P Another possibility to be considered is that B[a]P may have a prolonged half-life as a result of chronic treatment and...
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BIOTECHNOLOGY MOLECULAR STUDIES AND NOVEL APPLICATIONS FOR IMPROVED QUALITY OF HUMAN LIFE potx
... Azlan1 and Toshio Omori1 of Systems Engineering and Science, Department of Bioscience and Engineering, Shibaura Institute of Technology, 2Department of Biotechnological Research, Ministry of Science ... increasing the pH and therefore the formation of glazing of struvite, carbonate of calcium and/ or apatite, causing the formation of kidney stones In the South-west coast of India, a group of scientists ... common approaches and polymerization techniques used to fabricate PEG scaffolds with 3D spatial and temporal and/ or spatial variations in physical, mechanical, and bio-functional cues of the native...
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Báo cáo y học: " Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4" pot
... identification of HTLV-3 and HTLV-4 in only four persons limits an evaluation of the disease potential and secondary transmissibility of these novel viruses [6,8,24] However, complete genomic sequences of ... intervals for the origin of HTLV-2 as it migrated out of Africa and Asia and into the Americas via the Bering land bridge and 40,000 – 60,000 ya as confidence intervals for the origin of HTLV-1 in Melanesia ... organization and characterization of the HTLV4(1863LE) structural and enzymatic proteins, and the LTR The genomic structure of HTLV-4(1863LE) was similar to that of other PTLVs and included the...
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Báo cáo y học: " Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy" pps
... effects of curcumin were mediated by down-regulating the sustained activation of PI3K/Akt and/ or IBa kinase (IBaK) and nuclear translocation of NF-B and STATs induced by growth factors (Figures and ... radiosensibilizing and chemosensibilizing effects on glioma cells via the up-regulation of p53, p21WAF1 and the inhibitor of growth (ING4), inhibition of NF-B and AP-1 transcriptional activities and stimulation ... cascade and GLI-1 expression [51] Additionally, it has also been reported that the treatment of PC3 cells with curcumin in vitro reduced the expression level and activity of CC motif ligand (CCL2) and...
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Tài liệu Plug and Play Splitter Architectures Drive Operational Savings doc
... churn, and easier maintenance and troubleshooting Early decisions to splice Many early FTTP deployments sparked concerns about loss budgets Since the use of connectors resulted in more loss than ... less loss and enabled the addition of more splitters as the network grew However, there were also a few downsides to splicing the F1 cables to the splitters The first issue is the amount of time ... to test both the F1 and the splitter would require breaking a splice, splicing connectors to both the F1 and the splitter, running the tests, cutting off the connectors, and re-splicing the F1...
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Tài liệu TRADITIONAL AND NOVEL RISK FACTORS IN ATHEROTHROMBOSIS pptx
... migration, and differentiation of EPCs and their homing to sites of vascular injury are complex and involve several mediators and receptors, such as P-selectin glycoprotein ligand-1, CXC chemokine, and ... narrowing and irregularity of the luminal surface in erosion The morphologic characteristics include an abundance of SMCs and proteoglycan matrix, expecially versican and hyaluronan, and disruption of ... Immunofluorescence images of thrombus on rabbit femoral artery Representative immunofluorescent microphotographs of thrombi 15 minutes after balloon injury of normal femoral artery and of atherosclerotic...
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Traditional and Novel Risk Factors in Atherothrombosis Edited by Efraín Gaxiola pot
... migration, and differentiation of EPCs and their homing to sites of vascular injury are complex and involve several mediators and receptors, such as P-selectin glycoprotein ligand-1, CXC chemokine, and ... narrowing and irregularity of the luminal surface in erosion The morphologic characteristics include an abundance of SMCs and proteoglycan matrix, expecially versican and hyaluronan, and disruption of ... Immunofluorescence images of thrombus on rabbit femoral artery Representative immunofluorescent microphotographs of thrombi 15 minutes after balloon injury of normal femoral artery and of atherosclerotic...
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Coronary Artery Disease – New Insights and Novel Approaches Edited by Angelo Squeri pdf
... particles vary in size and density, mainly because of differences in the number of apolipoprotein (apo) particles and the amount of Chol ester in the core of HDL molecule The majority of lipoprotein ... and syndrome X, as components of the metabolic syndrome37 Their presence is often accompanied by increased TGs and low HDL While overproduction of VLDLs by the liver and increased secretion of ... regulation of structure and function of both the heart and vessel wall Under pathologic conditions, the ability of the heart and vessel wall to generate Ang II is increased, because of increased...
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Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... increasing concentrations of TSAOe3T, resulting in loss of dimer stability of 4.0 and 3.2 kcalÆmol)1 for p66/p51 and p66/p66 forms of HIV-1 RT, respectively [44] This loss of energy is not sufficient ... salt bridge between D29 and R87 of one subunit and R8 of the other subunit Thermodynamic analyses of the dimeric PR molecule indicates a Gibbs energy of dimer stabilization of 10 kcal/mol at 25 ... intrinsically asymmetric Thermodynamic evaluations of the association between the p66 and p51 subunits of RT have estimated a Gibbs free energy of dimer stabilization of approximately 10–12 kcalÆmol)1,...
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Báo cáo khoa học: "Formal aspects and parsing issues of dependency theory Vincenzo Lombardo and Leonardo Lesmo" potx
... W ) and two integers g and v is a word object of the grammar Given a grammar G, the set of word objects of G is Wx(G)={ ~tXv/ IX, v_>0, xe W u {e} } A pair consisting of a category X (e C) and ... has a n u m b e r of elements which depends on the maximum length of the chain of predictions Since the number of rules is O(n), the size of the stack is O(n) The elements of T-stack contain ... formalism and an Earley-type parser with a polynomial complexity The introduction of non lexical categories in a dependency formalism allows the treatment of long distance dependencies and of free...
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Báo cáo khoa học: Investigation of leucine-rich repeat kinase 2 Enzymological properties and novel assays pptx
... implicated in PD, and understanding its properties and functions will aid in our understanding of disease pathology and progression Experimental procedures Chemicals and reagents All compounds and proteins ... that of G2019S LRRK2, which had an apparent Km of 134 ± lm (P < 0.01; Fig 4C) 35 LRRKtide 32P incorporation Activity of wild-type and G2019S mutant forms of LRRK2 A LRRKtide 32P incorporation of ... 20- Fig Characterization of LRRK2 proteins (A) Coomassie Bluestained gel of lg of each GST–LRRK2 protein preparation separated by SDS ⁄ PAGE (B) Western blot of 0.5 lg of wild-type (WT) LRRK2...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
... dominant nature of the disease suggests a toxic gain -of- function of the mutated protein that disrupts normal cellular functions and causes neuronal death [3] Loss -of- function of the wild-type ... transcription caspase-6, and caspase-3 Cleavage of Bid and release of cytochrome c and apoptosis-inducing factors from the mitochondria are also observed Coexpression of wild-type htt exon and Hippi decreases ... models, brains of transgenic animals, and post-mortem brains of HD patients [2] Aggregate formation is enhanced with the increase in the number of glutamines in vitro and in vivo, and is believed...
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Goethe and the Molecular Aesthetic ppt
... parts of the brain, so that there is an integration not only of various kinds of sensory data like touch and sight, but also of sensory data with higher order thinking processes and of both of these ... well-versed in his work and saw its relevance to her own, not only in terms of issues of biology but of issues of how science is done as well In both Natural Philosophy and The Mind and the Eye, she ... and the same can be said of Arber’s Both were interested in the relationships of organic parts to the whole, saw a connection between the objective and subjective, and took an idealist view of...
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Erectile Dysfunction – Disease-Associated Mechanisms and Novel Insights into Therapy Edited by Kenia Pedrosa Nunes potx
... is still NO, and the deep understanding of NO/cGMP signaling has supported, not only the molecular understanding of the tumescence, but also added significantly in the treatment of the ED, including ... Changes of adrenal hormones The role of adrenal hormones and their changes are not well established in the etiology of ED Studies have correlated the low levels of dehydroepiandrosterone with ED Androstenedione ... management of ED QoL is used to assess the overall well-being of a person Most of the medical treatments for ED now are focussing on improving QoL of patients (Althof, 2002) What is quality of life/...
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NUTRITIONAL ASPECTS and CLINICAL MANAGEMENT of CHRONIC DISORDERS and DISEASES doc
... Prevention and Treatment, Jana Parízková and Andrew Hills Alcohol and Coffee Use in the Aging, Ronald R Watson Handbook of Nutrition in the Aged, Third Edition, Ronald R Watson Vegetables, Fruits, and ... visiting professor at the Universities of Cape Town, Tel Aviv, and Lyon, and at the Pasteur and Weizmann Institutes He is a fellow of the American Association for the Advancement of Science and of the ... He is a member of numerous professional societies and has been on the editorial boards of The American Journal of Physiology, The Journal of Nutrition, and The American Journal of Clinical Nutrition...
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Báo cáo khoa học: Mechanistic aspects and redox properties of hyperthermophilic L-proline dehydrogenase from Pyrococcus furiosus related to dimethylglycine dehydrogenase⁄oxidase potx
... ion of FAD cofactor with an m ⁄ z peak of 787 identical to that of the authentic FAD standard The m ⁄ z peak at 825 represents the K+ adduct of released FAD cofactor The m ⁄ z peaks of 348 and ... detailed report of the kinetic and spectroscopic properties of this novel type of PRODH Results Analysis of a and b subunit sequences Sequence analysis of both subunits suggests the presence of an ADP-binding ... H]+ ion of both AMP and FMN, respectively, which result from partial hydrolysis of FAD cofactor during protein heat treatment The m ⁄ z peak of 496 represents the K+ adduct of the FAD cofactor...
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Báo cáo khoa học: Structural aspects and biological properties of the cathelicidin PMAP-36 pot
... 2005 FEBS M Scocchi et al Structure and antimicrobial activity of PMAP-36 Fig CD spectra of the synthetic PMAP36 peptides Spectra of PMAP-36(1–35)2 (A) and of the truncated fragment PMAP-36(1– ... TFE (– –), and with 25% (–ÆÆ–ÆÆ–) and 50% (v/v) TFE Table shows the antimicrobial activity of the monomeric and dimeric peptides towards several Gram-positive and Gram-negative bacteria and two ... ATCC 27853, and clinical isolates of P mirabilis, C albicans and C neoformans Bacteria and fungi were maintained on MH agar or on solid Sabouraud agar dextrose medium, respectively, and were subcultured...
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Imaging of the Breast – Technical Aspects and Clinical Implication Edited by Laszlo Tabar pptx
... used to increase spatial resolution, and thus improve lesion morphology evaluation and diagnostic accuracy In a proof -of- concept study, Kuhl et al compared the accuracy of both 1.5 and 3.0 Tesla ... intensity of T2-weighted images and the presence of cysts improved the diagnostic accuracy, with a sensitivity of 91% and a specificity of 65% (Baltzer et al., 2011) Fig Example of the added value of ... based on consensus opinions of professionals and experts from the executive committee of the Society of Breast Imaging and the members of the Breast Imaging Commission of the ACR These recommendations...
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Báo cáo khoa học: Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes Formation of modified and oxidized particles pot
... examined, modification of Trp and Lys was more rapid with GA than with MG and the loss of Lys appears to occur earlier than that of Trp in the MG system With GA the loss of these two amino acids ... and CA (Fig 1C) were completely consumed and CL (Fig 1D) partly consumed ( 70% and 20%, respectively) with a concomitant accumulation of CEO(O)H (Fig 1E) (loss of TOH significant at days, loss ... extensive loss of Trp fluorescence was detected with high concentrations of GA that was time- and concentration-dependent (Fig 4A) and these changes occurred in the absence of Cu2+; for 10 and 100...
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Báo cáo khoa học: "ON REPRESENTING GOVERNED PREPOSITIONS AND HANDLING "INCORRECT" AND NOVEL PREPOSITIONS" ppt
... (4) blends, and (5) substitution of a semantically appropriate preposition for a syntactically determined one A small percentage of the non-standard use of prepositions appears to be random 1.3 ... APPLICATIONS OF THIS WORK In a theoretical linguistics f o r u m (Blejcr and Flank 1988), we argued that these examples of the use of non-standard prepositions to mark arguments (1) represent the kind of ... of prepositional case marking, and thus facilitate handling non-standard and novel use of prepositions to mark arguments The second contribution is our typology of errors in preposition usage...
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